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Research Studies

Division of Gastroenterology, Hepatology and Nutrition Research Studies

Find research studies available to children cared for by the Division of Gastroenterology, Hepatology and Nutrition team.

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Eligible age

Diet and Motility in IBS

This study seeks to characterize dietary intake in children with IBS and explore severity of symptoms and quality of life. This study uses the G-Tech wireless patch system to define patterns of gut motility in patients with IBS and associate these patterns with dietary intake and GI symptoms. Participants will wear the patches for 7 days as a part of the study. They can be worn under clothing and participants can continue daily activities other than swimming, bathing (although they can shower), and exercising. Stool and urine samples will also be collected to explore the gut microbiome and its association with IBS symptoms, diet, and patterns of gut motility.

We are looking to partner with patients with a confirmed diagnosis of IBS between 8 and 18 years of age who are undergoing dietary modifications such as a low-FODMAP (fermentable oligosaccharides, disaccharides, monosaccharides and polyols) diet.

Phase: Pilot

Actively recruiting: Yes

Category: Adults, Children, One-Time Visit Studies

HEALTHY BITES

Teens ages 14-17 with BMI in the 85th percentile or above and without diabetes are invited to participate in the HEALTHY BITES Research Study. The purpose of this research study is to find out if we can develop a mobile health approach that can improve diet quality in teens.

Phase: Pilot

Actively recruiting: Yes

Category: Children, One-Time Visit Studies, Remote (Online / Phone Call Only) Studies

Hypnotherapy in Functional Abdominal Pain Disorders

The purpose of this study is to find out if a video-guided hypnotherapy (VGH) program will improve the symptoms of those with a functional abdominal pain disorder (FAPD). This program uses guided relaxation, intense concentration, and focused attention to achieve a heightened state of awareness. These techniques can be used to help some people change certain behaviors, and it is also used to treat chronic pain. VGH does not feature direct in-person interaction with a psychotherapist (mental health professional), but rather recorded sessions that can be viewed at any time at the discretion of the patient. This study will use the video-guided hypnotherapy program that has been developed by Jeffrey Lazarus, MD, FAAP. Dr. Lazarus is a general pediatrician with an extensive background in the use of clinical hypnosis in children. He has been certified as an Approved Consultant by the American Society of Clinical Hypnosis.

Phase: Pilot

Actively recruiting: Yes

Category: Adults, Children, Remote (Online / Phone Call Only) Studies

Pediatric IBD Fatigue Index, and the Pediatric IBD Disability Index Study

Kids with IBD (inflammatory bowel disease) often struggle with tiredness and difficulty doing everyday activities, which can make life harder, but there aren't good tools to measure these problems in children. This study aims to create special tools to measure fatigue and disability in kids aged 2-18. Researchers will talk to kids and their parents to find out what issues matter most and use this information, along with medical records, to design the tools. The goal is to help doctors track these problems better and improve care for children with IBD. This study is being done in collaboration with the Shaare Zedek Medical Center. Participants will be compensated for their time and effort, upon completion of the interview.

Phase: Phase I

Actively recruiting: Yes

Category: Adults, Children, One-Time Visit Studies, Remote (Online / Phone Call Only) Studies

Sleep and Growth Study 2

The Childrens Hospital of Philadelphia is seekinghealthy adolescents between the ages of 12-13, who are currently in the 7thgrade,to participate in the Sleep and Growth Study 2. The purpose of this research is to learn more about the changes in sleep and body size in adolescents as they transition from middle to high school. Participants will be asked to visit CHOP so that we can measure their bone density. Following this visit, participants will wear a sleep tracker over a 2-week period and speak to a team member by phone on three occasions about the types of food eaten in the previous 24 hours. If you and your child agree to participate, the study will involve 3 visits over approximately 2 years. All participants are compensated for their time and effort.For more information and study details, please call 215-590-2383, ext. 1, or emails_grow@chop.edu.

Phase: Phase I

Actively recruiting: No

Category: Children, Healthy Controls

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