Klinefelter and Other X and Y Chromosome Variations Program
Children and adolescents who have been diagnosed with Klinefelter syndrome and other X and Y chromosomes variations receive comprehensive care in the Klinefelter Program at Children's Hospital of Philadelphia (CHOP), where we address their changing needs from infancy through early adulthood.
We provide assessment, treatment and care planning — all during a single clinic appointment.
Our approach to care is highly individualized, based on the symptoms and needs of each child at each stage of their development and and in response to family concerns.
To address psychosocial needs of children and families, we offer ongoing support with a dedicated psychologist and social worker. Psychology and social work follow-up appointments are coordinated to occur at the same time as endocrine visits. Psychology visits are also available by telehealth.
How we serve you
Our deep understanding of chromosome variations guides the initial evaluation and follow-up care. Your child will be monitored for any complications, such as high cholesterol levels, diabetes or osteoporosis. We also watch for signs of puberty and developmental differences and offer treatment and referrals if your child needs them.
Why choose CHOP
The Klinefelter Program is part of CHOP’s Adrenal and Puberty Center, which has expertise in treating children with an array of conditions that may affect puberty and gonadal function. The Adrenal and Puberty Center is under the Division of Endocrinology and Diabetes, which has been consistently ranked among the very best in the country by U.S. News & World Report.
Meet your team
Your child benefits from having easy access to all members of our team, including clinicians and counselors from Endocrinology, Psychology, Genetics, Social Work and Reproductive Medicine.
Klinefelter and Other X and Y Chromosome Variations Program resources
We have created resources to help you find answers to your questions on chromosome variations so you feel confident in the care you are providing your child.
Patient stories
Preparing for your appointment
Our care will evolve as your child grows. See what you can expect from us at different stages of your child's development.
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