The purpose of this study is to find out how the brain learns to move in infants with and without brain injury. Some infants with brain injury later have cerebral palsy (CP), a condition that makes it hard for infants to learn how to move and control their balance, and others do not. Three groups of infants will participate- infants who had a brain injury and are at high risk for CP, infants who had a brain injury and are not at high risk for CP, and infants who are typically developing.

The purpose of this study to learn more about the brain function of females with Rett Syndrome and how it compares to the brain function of typically developing females. The primary investigator of the study is Dr. Eric Marsh. For our research to be successful we need to partner with families who have a typically developing daughter between the age of 1 and 17. If your child agrees to help us with our study she will be asked to:

• Complete intelligence testing
• Receive an Evoked Potential measurement - this is a non-invasive procedure similar to an EEG.
• Complete yearly follow up visits

We want to study brain responses during simulated driving and are currently looking for participants 12-17 years old or those who have had brain surgery. To do so, we'll have eligible participants come to CHOP for some non-invasive (safe) brain scans and drive using a simulator. If you are interested in learning more about the study, please contact Victoria Kaufman at kaufmanv@chop.edu or 267-425-4150.