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Pediatric Comprehensive Bone Marrow Failure Center News

Every person on your child’s team has the same goal: to see your child thrive. We provide medical care, emotional counseling and much more.

New patients, referrals and second opinions

Children’s Hospital of Philadelphia Researchers Discover that Acute Myeloid Leukemia Can Permanently Reprogram Stem Cells Through Inflammation

Mar 31, 2025

New research from Children’s Hospital of Philadelphia (CHOP) uncovered a previously unknown side effect of Acute Myeloid leukemia (AML), the second most common blood cancer in children, that leaves a long-lasting imprint on healthy blood-forming stem cells, influencing immune responses long after the disease has entered remission. The results were published recently in the journal Cancer Letters.

Children’s Hospital of Philadelphia Preclinical Study Unveils Promising New Treatment Approach for Fanconi Anemia Patients

Jan 28, 2025

In a preclinical study, researchers at Children’s Hospital of Philadelphia (CHOP) demonstrated a novel treatment strategy for patients with Fanconi anemia (FA), a rare genetic disease resulting in loss of blood-forming stem cells in the bone marrow. The researchers successfully used in situ mRNA delivered directly into the body by lipid nanoparticles (LNPs) to target bone marrow cells and transiently restore stem cell function in patients with FA.

Joe Oved, MD, Joins the Comprehensive Bone Marrow Failure Center at CHOP

Jul 15, 2019

Dr. Oved brings deep expertise to the group, having completed scientific and clinical training that included tenures as a Fulbright Fellow with the Weizmann Institute in Israel, the NYU School of Medicine with two years as a Howard Hughes Medical Fellow, followed by a residency in Pediatrics at NYP Weill Cornell Medical College.

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