Pediatric Comprehensive Bone Marrow Failure Center
Families come to the Pediatric Comprehensive Bone Marrow Failure Center at Children's Hospital (CHOP) of Philadelphia to receive a diagnosis, get a second opinion, or establish a comprehensive treatment plan. Bone marrow failure syndromes are diagnostically and therapeutically challenging, and the clinical expertise at CHOP can be helpful in making an individualized plan of care for your child.
Shwachman-Diamond Syndrome: Elizabeth’s Story

Born with a rare condition affecting her bone marrow, 2-year-old Elizabeth has large care teams at CHOP and her local hospital who coordinate to keep her growing and happy.
Why Choose Us?
The Pediatric Comprehensive Bone Marrow Failure Center has a history of excellence in bench-to-bedside clinical care, providing advanced genomic diagnostics and actionable scientific discovery.
Conditions We Treat
We offer complete diagnostic, therapeutic and support services for children with acquired and inherited bone marrow disorders including those listed here, and other inherited bone marrow failure syndromes.
Our Programs and Services
Children treated by the Bone Marrow Failure Program at CHOP will benefit from our expertise in genomic diagnostics and our state-of-the-art stem cell transplant facility.
Our Team
Meet the specialists who will care for your child and family while in treatment for a bone marrow failure disorder.