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Bronchiolitis Clinical Pathway – Emergency Department and Inpatient – Additional Treatment Considerations

Bronchiolitis Clinical Pathway – Emergency Department and Inpatient – Additional Treatment Considerations

Additional Treatment Considerations

May be considered in infants with significant respiratory distress that is not alleviated sufficiently by supportive care interventions.

Albuterol Studies have not demonstrated a consistent benefit for albuterol treatment in infants with typical bronchiolitis. An albuterol trial may be considered in children with features suggestive of possible asthma (recurrent wheezing, age > 12 mos, prior inhaled corticosteroid use).

Albuterol should not be continued if the child does not respond to test dose.
If responsive to albuterol test dose, may continue:
  MDI Frequency of every 1-4 hrs as needed
  Intermittent nebulization Frequency of every 2-6 hrs as needed
Racemic Epinephrine
  • α and β adrenergic agonist
  • Consider use in infants with increasing severe respiratory distress
  • Requires MD order/bedside assessment for administration
HFNC
  • HFNC is indicated to reduce work of breathing in infants with bronchiolitis or other lower respiratory conditions. Evidence of benefit for children > 12 mos is lacking.
  • Initiation of HFNC should be based on severe respiratory distress on repeated assessments not resolved with suctioning and supportive care.
    • Pausing to reassess has been shown to successfully reduce unnecessary use of HFNC.
    • Prior to initiation in ED, Attending assessment required.
  • HFNC should be titrated to minimum settings required to relieve work of breathing, usually 1.5-2 L/kg/min with a weight-based maximum.
  • HFNC is an expensive and resource-intensive therapy which should be weaned off as soon as possible once infants are improving.
  • Enteral feeding is safe and effective for infants receiving HFNC unless worsening with signs of impending respiratory failure.
Antibiotics
Hypertonic Saline
  • Current research does not support a role for routine use of hypertonic saline in the ED or inpatient unit.
  • Consider initiating a hypertonic saline regimen (standing every 6-8 hrs) in children with a prolonged hospital stay or those not showing improvement over the first
    48 hrs of admission.

 

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