Timothy P.L. Roberts, PhD

Timothy P.L. Roberts, PhD

Timothy P.L. Roberts, PhD, is Vice-chair of Research for the Department of Radiology and the Oberkircher Family Endowed Chair in Pediatric Radiology at Children's Hospital of Philadelphia.

Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

Education and Training

Fellowship

Postdoctoral Fellow - Department of Radiology, University of California San Francisco, San Francisco, CA

Undergraduate Degree

BA in Natural Sciences - Cambridge University, Cambridge, UK

Graduate Degree

PhD - Cambridge University, Cambridge, UK
MA - Cambridge University, Cambridge, UK

Titles and Academic Titles

Vice Chair of Research, Department of Radiology

Oberkircher Family Endowed Chair in Pediatric Radiology

Professor of Radiology, Perelman School of Medicine at the University of Pennsylvania

Departments and Services

Publications

Papers

2017

Ouyang M, Liu P, Jeon T, Chalak L, Heyne R, Rollins NK, Licht DJ, Detre JA, Roberts TP, Lu H, Huang H.  Heterogeneous increases of regional cerebral blood flow during preterm brain development: Preliminary assessment with pseudo-continuous arterial spin labeled perfusion MRI.  Neuroimage. 2017 Feb. 147:233-242.

Port RG, Gaetz W, Bloy L, Wang DJ, Blaskey L, Kuschner ES, Levy SE, Brodkin ES, Roberts TPL.  Exploring the relationship between cortical GABA concentrations, auditory gamma-band responses and development in ASD: Evidence for an altered maturational trajectory in ASD. Autism Res. 2017 Apr; 10(4) 593-607.

Leary SES, Park JR, Reid JM, Ralya AT, Baruchel S, Wu B, Roberts TPL, Liu X,     Minard CG, Fox E, Weigel BJ, Blaney S.  Pediatric phase 1 trial and pharmacokinetic study of trebananib in relapsed solid tumors ADVL1115: A Children’s Oncology Group Phase 1 consortium report.  Clin Cancer Res. [Epub ahead of print] 2017 July 27.

Owen JP, Bukshpun P, Pojman N, Thieu T, Chen Q, Lee J, D’Angelo D, Glenn OA, Hunter JV, Berman JI, Roberts TP, Buckner R, Nagarajan SS, Mukherjee P, Sherr EH.

Brain MR Imaging Findings and Associated Outcomes in Carriers of the Reciprocal Copy Number Variation at 16p11.2. Radiology [Epub ahead of print] 2017 Aug 8.

2016

Edgar JC, Fisk CL 4th, Liu S, Pandey J, Herrington JD, Schultz RT, Roberts TP. Translating adult Electrophysiology Findings to younger patient populations: difficulty measuring 40-Hz auditory steady-state responses in typically developing children and children autism spectrum disorder. Dev Neurosci 2016 38(1):1-14.

2015

Jenkins J 3rd, Chow V, Blaskey L, Kuschner E, Qasmieh S, Gaetz L, Edgar JC, Mukherjee P, Buckner R, Nagarajan SS, Chung WK, Spiro JE, Sherr EH, Berman JI, Roberts TP: Auditory Evoked M 100 Response Latency is Delayed in Children with 16p11.2 Deletion but not 16p11.2 Duplication. Cereb Cortex Feb. 2015 Notes: [Epub ahead of print]

Edgar JC, Heiken K, Chen YH, Herrington JD, Chow V, Liu S, Bloy L,  Huang M, Pandey J, Cannon KM, Qasmieh S, Levy SE, Schultz RT, Roberts TP:  Resting-state alpha in autism spectrum disorder and alpha associations with thalamic volume. J Autism Dev Disord. 45(3): 795-804, March 2015.

Port RG, Anwar AR, Ku M,Carlson GC, Siegel SJ, Roberts TP: Perspective MEG biomarkers in ASD: pre-clinical evidence and clinical promis of electrophysiological signatures. Yale J Biol Med. 88(1), 25-36 March 2015.

Berman JI, Liu S, Bloy L, Blaskey L, Roberts TP, Verma R: Alpha-to-gamma phase-amplitude coupling methods and application to autism spectrum disorder. Brain Connect.  5(2): 80-90, April 2015

Chang YS, Owen JP, Pojman NJ, Thieu T, Bukshpun P, Wakahiro ML, Berman JI, Roberts TP, Nagarajan SS, Sherr EH, Mukherjee P. White matter changes of neurite density and fiber orientation dispersion during human brain maturation. PlOS One 10(6) June 2015.

Edgar JC, Fisk Iv CL, Berman JI, Chudnovskaya D, Liu S, Pandey J, Herrington JD, Port RG, Schultz RT, Roberts TP. Auditory encoding abnormalities in children with autism spectrum disorder suggest delayed development of auditory cortex. Mol Autism. 2015 Dec 30 (6):69.

2014

Breuer L, Dammers J, Roberts TP, Shah NJ.: A constrained ICA approach for real-time cardiac artifact rejection in magnetoencephalography. IEEE Trans Biomed Eng. 61(2): 405-14, Feb. 2014.

Gaetz W, Bloy L, Wang DJ, Port RG, Blaskey L, Levy SE, Roberts TP: GABA Estimation in Brains of Children on the Autism Spectrum: Measurement Precision and Regional Cortical Variation. Neuroimage 86: 1-9, February 2014.

Roberts TP, Heiken K, Zarnow D, Dell J, Nagae L, Blaskey L, Solot C, Levy SE, Berman JI, Edgar JC.: Left Hemisphere Diffusivity of the Arcuate Fasciculus: Influences of Autism Spectrum Disorder and Language Impairment. AJNR Am J Neuroradiol. 35(3): 587-92, March 2014.

Roberts TP, Paulson DN, Hirschkoff E, Pratt K, Mascarenas A, Miller P, Han M, Caffrey J, Kincade C, Power B, Murray R, Chow V, Fisk C, Ju M, Chudnovskaya D, Dell J, Golembski R, Lam P, Blaskey L, Kuschner E, Bloy L, Gaetz W, Edgar JC: Artemis 123: development of a whole-head infant and young child MEG system. Front Hum Neurosci 8: 99, March 2014.

Owen JP, Chang YS, Pojman NJ, Bukshpun P, Wakahiro ML, Marco EJ, Berman JI, Spiro JE, Chung WK, Buckner RL, Roberts TP, Nagarajam SS, Sherr EH, Mukherjee P; Simons VIP Corsortium: Aberrant white matter microstructure in children with 16p11.2 deletions. J Neurosci. 34(18): 6214-23, April 2014.

Victoria T, Jaramillo D, Roberts TP, Zarnow D, Johnson AM, Delgado J, Rubesova E, Vossough A.: Fetal magnetic resonance imaging: jumping from 1.5 to 3 tesla (preliminary experience). Pediatr Radiol. 44(4): 376-86, April 2014.

Brennan J, Lignos C, Embick D, Roberts TP.: Spectro-temporal correlates of lexical access during auditory lexical decision. Brain Lang. 133: 39-46, June 2014.

Edgar JC, Lanza MR, Daina AB, Monroe JF, Khan SY, Blaskey L, Cannon KM, Jenkings J 3rd, Qasmieh S, Levy SE, Roberts TP: Missing and delayed auditory responses in young and older children with autism spectrum disorders. Front Hum Neuroscience 6: 417, June 2014.

Ingalhalikar M, Parker WA, Bloy L, Roberts TP, Verma R.: Creating multimodal predicators using missing data: Classifying and subtyping autism spectrum disorder. J Neurosci. Methods 235C: 1-9, June 2014.

Breuer L, Dammers J, Roberts TP, Shan NJ.: Ocular and cardiac artifact rejection forreal-time analysis in MEG. J Neurosci Methods 15: 105-14, Aug 2014.

Qureshi AY, Mueller S, Snyder AZ, Mukherjee P, Berman JI, Roberts TP, Nagaraja SS, Spiro JE, Chung WK, Sherr EH, Buckner RL; Simons VP Consortium: Opposing brain differences in 16p11.2 deletion and duplication carriers. J Neurosci. 34(34): 11199-211, August 2014.

Ghanbari Y, Bloy L, Shankar V, Edgar JC, Roberts TP: Functionally driven brain networks using multi-layer graph clustering. Med Image Comput Comput Assist Interv. 17(Pt. 3): 113-20, 2014.

Port RG, Gandal MJ, Roberts TP, Siegel SJ, Carlson GC: Convergence of circuit dysfunction in ASD: a common bridge between diverse genetic and environmental risk factors and common clinical electrophysiology. Front Cell Neurosci. 8(18): 414, Dec. 2014.

2013

Monroe JF, Grinn M, Pinkham A, Loughead J, Gur RC, Roberts TP, Chiristopher Edgar J. : The fusiform response to faces: Explicit versus implicit processing of emotion. Human Brain Mapp 34(1): 1-11, Jan. 2013.

Saunders JA, Tatard-Leitman VM, Suh J, Billingslea EN, Roberts TP, Siegel SJ: Knockout of NMDA Receptors in Parvalbumin Interneurons Recreates Autism-Like Phenotypes. Autism Res. 6(2): 69-77, April 2013.

Gaetz W, Liu C, Zhu H, Bloy L, Roberts TP.: Evidence for a motor gamma-band network governing response interference. Neuroimage 74: 245-53, July 2013.

Glade Bender JL, Lee A, Reid JM, Baruchel S, Roberts T, Voss SD, Wu B, Ahern CH, Ingle AM, Harris P, Weigel BJ, Blancey SM: Phase I Pharmacokinetic and Pharmacodynamic Study of Pazopanib in Children with Soft Tissue Sarcoma and Other Refractory Solid Tumors: A Children's Oncology Group Phase I Consortium Reports. J Clin Oncol 31(24): 3034-43, July 2013.

Berman JI, Lanza MR, Blaskey L, Edgar JC, Roberts TP: High Angular Resolution Diffusion Imaging Probabilistic Tractography of the Auditory Radiation. AJNR Am J Neuroradiol. 34(8): 1573-8, August 2013.

Edgar JC, Khan SY, Blaskey L, Chow VY, Rey M, Gaetz W, Cannon KM, Monroe JF,Cornew L, Qasmieh S, Liu S, Welsh JP, Levy SE, Roberts TP: Neuromagnetic Oscillations Predict Evoked-Response Latency Delays and Core Language Deficits Autism Spectrum Disorders. J Autism Dev Disord. Aug 2013 Notes: [Epub ahead of print]

Ghanbari Y, Bloy L, Edgar JC, Blaskey L, Verma R, Roberts TP: Joint Analysis of Band-Specific Functional Connectivity and Signal Complexity in Autism. J Autism Dev Disord. Aug 2013 Notes: [Epub ahead of print]

de Blank PM, Berman JI, Liu GT, Roberts TP, Fisher MJ.: Fractional Anistropy of Opic Radiations is Associated with Visual Acuity Loss in Optic Pathway Gliomas of Neurofibromatosis Type 1. Neuro Oncol 15(8): 1088-95, Aug. 2013.

Roberts TP, Lanza MR, Dell J, Qasmieh S, Hines K, Blaskey L, Zarnow DM, Levy SE, Edgar JC, Berman JI: Maturational differences in thalamocortical white matter microstructure and auditory evoked response latencies in autism spectrum disorders. Brain Res 1537: 79-85, Nov 2013.

Owen JP, Ziv E, Bukshpun P, Pojman N, Wakahiro M, Berman JI, Roberts TP, Friedman EJ, Sherr EH, Mukherjee P.: Test-Retest Reliability of Computational Network Measurements Derived from the Structural Connectome of the Human Brain. Brain Connect 3(2): 160-76, 2013.

Monroe JF, Griffin M, Pinkham A, Loughead J, Gur RC, Roberts TP, Christopher Edgar J. The fusiform response to faces: Explicit versus implicit processing of emotion. Hum Brain Mapp (2013) 34(1):1-11

2012

Roberts TP, Heiken K, Khan SY, Qasmieh S, Solot C, Blaskey L, Parker WA, Verma R, Edgar JC. Delayed magnetic mismatch negativity field, but not auditory M100 response, in Specific Language Impairment Neuroreport 2012

Cornew L, Roberts TP, Blaskey L, Edgar JC: Resting-state oscillatory activity in autism spectrum disorders. J Autism Dev Disord. 42(9): 1884-94, Sept. 2012.

Gaetz W, Roberts TP, Singh KD, Muthukumaraswamy SD: Functional and structural correlates of the aging brain.  Relating visual cortex (V1) gamma band responses to age-related structural change. Human Brain Mapping 33(9): 2035-46, Sept. 2012.

Nagae LM, Zarnow DM, Blaskey L, Dell J, Khan SY, Qasmieh S, Levy SE, Roberts TP: Elevated Mean Diffusivity in Left Hemisphere Superior Logitudinal Fasciculus in Autism spectrum Disorders Increases with more Profound Language Impairment. AJNR Am J Neuroradiol 33(9): 1720-5, Oct. 2012.

Saunders JA, Gandal MJ, Roberts TP, Siegel SJ: NMDA antagonist MK801 recreates auditory electrophysiology disruption present in autism and other neurodevelopmental disorders. Behav Brain Res. 234(2): 233-7, Oct. 2012.

Ghanbari Y, Bloy L, Batmanghelich K, Roberts TP, Verma R: Dominant component analysis of electronphysiological connectivity newtworks. Med Image Comput Comput Assist Interv. 15(Pt. 3): 231-8, 2012.

Ingalhalikar M, Parker WA, Bloy L, Roberts TP, Verma R: Using multiparametric data with missing features for learning patterns of pathology. Med Image Comput Comput Assist Interv. 15(Pt. 3): 468-75, 2012.

Ingalhalikar M, Smith AR, Bloy L, Gur R, Roberts TP, Verma R: Identifying sub-populations via unsupervised cluster analysis on multi-edge similarity graphs. Med Image Comput Comput Assist Interv. 15(Pt. 2): 254-61, 2012.

Bloy L, Ingalhalikar M, Eavani H, Schultz RT, Roberts TP, Verma R. White matter atlas generation using HARDI based automated parcellation. Neuroimage. (2012) 59(4): 4055-63.

Gaetz W, Roberts TPL, Singh KD, Muthukumaraswamy SD. Functional and structural correlates of the aging brain: Relating visual cortex (V1) gamma band responses to age-related structural change. Human Brain Mapping (2012) 33(9):2035-46

2011

Tavabi K. Embick D, Roberts TP. Word repetition priming-induced oscillations in auditory cortex: a magnetoencephalography study. Neuroreport (2011) 22(17):887-91.

Bloy L, Ingalhalikar M, Eavani H, Roberts TP, Schultz RT, Verma R. HARDI based pattern classifiers for the identification of white matter pathologies. Med Image Comput Comput Assist Interv. (2011);14(Pt 2):234-41.

Tavabi K, Embick D, Roberts TPL, Spectral-temporal analysis of cortical oscillations during lexical processing. Neuroreport (2011) 22(10):474-8

Ingalhalikar M, Parker D, Bloy L, Roberts TP, Verma R.  Diffusion based abnormality marks of pathology: Toward learned diagnostic prediction of ASD.  Neuroimage, (2011) 57:918-27.

Gaetz W, Edgar JC, Wang DJ, Roberts TP. Relationg MEG measured motor cortical oscillations to resting y-Aminobutyric acid (GABA) concentration. Neuroimage (2011) 55(2):616-21

Roberts TP, Cannon KM, Tavabi K, Blaskey L, Khan S, Monroe JF, Qasmieh SA, Levy SE, Edgar JC.  Auditory Magnetic Mismatch Field Latency: A Biomarker for Language Impairment in Autism.  Biol. Psychiatry (2011)  70:263-9.

Bernhardt A, Wilson MW, Settecase F, Evans L, Malba V, Martin AJ, Saeed M, Roberts TP, Arenson RL, Hetts SW. Steerable Catheter Microcoils for Interventional MRI: Reducing Resistive Heating. Acad Radiol. (2011) 18(3):270-6

Settecase F, Hetts SW, Martin AJ, Roberts TP, Bernhardt AF, Evans L, Malba V, Saeed M, Arenson RL, Kucharzyk W, Wilson MW. RF Heating of MRI-Assisted Catheter Steering Coils for Interventional MRI. Acad Radiol (2011) 18(3):277-85

2010

Gandal MJ, Edgar JC, Ehrlichman RS, Mehta M, Roberts TP, Siegel SJ.  Validating gamma oscillations and delayed auditory responses as translational biomarker of autism: Biol Psychiatry (2010) 68(12):1100-6

Kassner A, Roberts T, Moran, Silver, Mikulis D. rTPA increases BBB disruption in AIS: An MR imaging permeability study. AJNR 30(10):1864-9

Schwartz ES, Edgar JC, Gaetz WC, Roberts TP.  Magnetoencephalography,  Pediatr Radiol (2010) Jan:40(1):50-8

Roberts TP, Khan SY, Rey M, Monroe J, Cannon K, Blaskey L, Woldoff S, Qasmieh S, Gandal M, Schmidt G, Zarnow DM, Levy SE, Edgar JC; MEG Detection of Delayed Auditory Evoked Responses in Autism Spectrum Disorders: Towards An Imaging Biomarker for Autism: Autism Res. (2010) Feb; 3(1); 8-18  

Chen YH, Edgar JC, Holroyd T, Dammers J, Thönnessen H, Roberts TP, Mathiak K. Neuromagnetic oscillations to emotional faces and prosody.  Eur J Neurosci. (2010) 31(10):1818-27 

Port  RE, Bernstein LJ, Barboriak DP, Xu L, Roberts TP, van Bruggen N:      Noncompartmental kinetic analysis of DCE-MRI data from malignant tumors:                  Application to glioblastoma treated with bevacizumab. Magn Reson Med (2010) 64(2), 408-417 

Ingalhalikar M, Kanterakis S, Gur R, Roberts TP, Verma R.  DTI based diagnostic prediction of a disease via pattern classification.  Med Image Comput Comput Assist Interv. (2010); 13(Pt 1): 558-65.

2009

Chen Y, Dammers J, Boers F, Leiberg S, Edgar JC, Roberts TP, Mathiak K.  The Temporal Dynamics of Insula Activity to Disgust and Happy Facial Expressions: A Magnetoenecphalography Study. Neurolmage (2009) Oct. 1;47(4):1921-8

Schmidt G, Roberts T, Oram Cardy JE, Rey M. Decision on Absence of M100 Source Asymmetry in Autism Associated with Language Functioning.  NeuroReport (2009) Jul 15; 20(11):1037-41

Roberts TP, Khan S, Dell J, Blaskey L, Zarnow D, Levy S, Edgar JC. Developmental Correlation of Diffusion anisotropy with Auditory Evoked Response. NeuroReport  (2009) 20(18):1586-91

2008

Schwartz ES, Dlugos DJ, Storm PB, Dell J, Magee R, Flynn TP, Zarnow DM, Zimmerman RA, Roberts TP.  Magnetoencephalography for Pediatric Epilepsy: How We Do It. Am J Neuroradiol Feb.13,(2008)as 10.3174/ajnr.A1029

Roberts TP, Schmidt, Egeth M, Blaskey L, Rey M., Edgar JC, Levy S.   Electrophysiological signatures: Magnetoencephalographic studies of the Neural correlates of language impairment in autism spectrum disorder. Int. J. Psychophysiol. (2008)  Feb;68:149-160.

Oram Cardy JE, Flagg EJ, Roberts W, Roberts TP. Auditory evoked fields predict Language ability and impairment in children.  Int J. Psychophysiol. (2008) Feb;68:170-175.

Sitartchouk I, Roberts HC, Pereira AM, Bayanati H, Waddell T, Roberts TP. Computed Tomography Perfusion Using First Pass Methods for Lung Nodule Characterization. Invest Radiol.  (2008) Jun;43(6):349-358.

2007

Ladabaum U, Roberts TP, McGonigle D. Gastric fundic distension activates fronto-limbic structures but not primary somatosensory cortex: a functional magnetic resonance imaging study. Neuroimage 34(2):724-32 (2007)

Haider MA, Sitartchouk I, Roberts TP, Fyles A, Hashmi AT, Milosevic M. Correlations between dynamic contrast-enhanced magnetic resonance imaging-derived measures of tumor microvasculature and interstitial fluid pressure in patients with cervical cancer. J. Magn Reson Imaging 25(1):153-9 (2007)

Settecase F, Sussman MS, Roberts TP. A new temperature-sensitive contrast mechanism for MRI: Curie temperature transition-based imaging. Contrast Media Mol Imaging (2007)

Roberts TP, Schwartz ES.  Principles and implementation of diffusion-weighted and diffusion tensor imaging.  Pediatr Radiol. Aug; 37(8); 739-748 (2007)

Roberts  TP, Mikulis D.  Neuro MR: Principles.  J Magn Reson Imaging Oct;26(4): 823-27 (2007)

Settecase F, Sussman MS, Wilson MW, Hetts S, Arenson RL, Malba V, Bernhardt AF,  Kucharczyk W, Roberts TP. Magnetically-assisted remote control (MARC) steering of endovascular catheters for interventional MRI: a model for deflection and design implications.  Med Phys Aug;34(8):3135-42 (2007)

Mikulis DJ, Roberts TP. Neuro MR: Protocols.  J Magn Reson Imaging Oct;26(4):838-47 (2007)

2006

Gage N, Robert TP, Hickok G. temporal resolution properties of human auditory cortex. Reflections in the neuromagnetic auditory evoked M100 component. Brain Res 1069(1):166-71 (2006)

Flagg EJ, Oram Cardy JE, Roberts TPL. MEG detects neural consequences of anomalous nasalization in vowel-consonant pairs. Neurosci Lett 397(3):263-8 (2006)

Bitar R, Leung G, Perng R, Tadros S, Moody AR, Sarrazin J, McGregor C, Chritakis M, Symsons S, Nelson A, Roberts TPL. MR pulse sequences: what every radiologist wants to know but is afraid to ask. Radiographics. 26(2):513-37 (2006)

Lange T, Dydak U, Roberts TP, Rowley HA, Bjeljac M, Boesiger P. Pitfalls in Lactate Measurements at 3T. AJNR Am J Neuroradiol. 27(4):895-901 (2006)

Oram Cardy J, Flagg E, Roberts W, Brian J, Roberts TPL. Magnetoencephalography identifies rapid temporal processing deficit in autism and language impairment. Neuroreport. 16(4):329-332 (2005)

Martin AJ, Saloner DA, Roberts TP, Roberts H, Weber OM, Dillon WP, Cullen S, Halbach V, Dowd CF, Higashida RT. Carotid stent delivery in an XMR suite: immediate assessment of the physiologic impact of extracranial revascularization. Am. J. Neuroradiol. 26:531-7 (2005)

Oram Cardy J, Flagg E, Roberts W, Roberts TP. Delayed mismatch field for speech and non-speech sounds in children with autism. Neuroreport 16(5):521-5 (2005)

Inouchi M, Kubota M, Ferrari P, Roberts TP. The elicitation of phonological and semantic neuromagnetic field components by non-words in human auditory sentence comprehension. Neurosci Lett. 380:116-121 (2005)

Roberts TPL, Liu F, Kassner A, Mori S, Guha A. Fiber density index correlates with reduced fractional anisotropy in white matter of patients with glioblastoma. Am. J. Neuroradiol. 26(9):2183-6 (2005)

Kubota M, Inouchi M, Ferrari P, Roberts TP. Human magnetoencephalographic evidence of early syntactic responses to c-selection violations of English infinitives and gerunds by L1 and L2 speakers. Neurosci Lett. 384:300-304 (2005)

Preda A, Turetschek K, Daldrup H, Floyd E, Novikov V, Shames DM, Roberts TP, Carter WO, Brasch RC. The Choice of Region of Interest Measures in Contrast-Enhanced Magnetic Resonance Image Characterization of Experimental Breast Tumors. Invest Radiol. 2005; 40(6):349-354.

Haider MA, Milosevic M, Fyles A, Sitartchouk I, Yeung I, Henderson E, Lockwood G, Lee T-Y, Roberts TPL. Assessment of the tumor microenvironment in cervix cancer using dynamic contrast enhanced CT, interstitial fluid pressure and oxygen measurements. Int J. Radiat. Oncol. Biol. Phys. 2005; 62(4):1100-1107

Kassner A. Roberts T, Taylor K, Silver F, Mikulis D. Prediction of hemorrhage in acute ischemic stroke using permeability MR imaging. AJNR Am J Neuroradiol 26(9):2213-7 (2005)

Preda A, Novikov V, Moglich M, Floyd E, Turetschek K, Shames DM, Roberts TP, Corot C, Carter WO, Brasch RC. Magnetic resonance characterization of tumor microvessels in experimental breast tumors usinga  slow clearance blood pool contrast agent (carboxymethyldextran-A2-Gd-DOTA) with histopathological correlation. Eur Radiol. 15(11):2268-75 (2005)

Roberts T. Technical and practical considerations for permeability modeling of dynamic contrast enhanced MRI. Acad Radiol 12:S34-7 (2005)

Flagg EJ, Cardy JE, Roberts W, Roberts TP. Language lateralization development in children with autism: insights from the late field magnetoencephalogram. Neurosci Lett 386(2):82-7 (2005)

2004

Oram Cardy J, Ferrari P, Flagg E, Roberts W, Roberts, TPL. Prominence of M50 auditory evoked response over M100 in childhood and Autism. Neuroreport, 15(12):1867-1870 (2004)

Roberts TPL, Flagg E, Gage NM. Vowel categorization induces departure of M100 latency from acoustic prediction. Neuroreport, 15(10):1679-1682 (2004)

Turetschek K, Preda A, Novikov V, Brasch RC, Weinmann HJ, Wunderbaldinger P, Roberts TP. Tumor microvascular changes in antiangiogenic treatment: assessment by magnetic resonance contrast media of different molecular weights. J Magn Reson Imaging. 20(1):138-44 (2004)

Kassner A, Roberts TP. Beyond perfusion: cerebral vascular reactivity and assessment of microvascular permeability. Top Magn Reson Imaging. 15(1):58-65 (2004)

Rowley HA, Roberts TP. Clinical perspectives in perfusion: neuroradiologic applications. Top Magn Reson Imaging. 15(1):28-40 (2004)

Lim CC, Roberts TP, Sitoh YY, Hui F. Rising signal intensity observed in extra-axial brain tumours - a potential pitfall in perfusion MR imaging. Singapore Med J. 44(10):526-30 (2003)

Wiart M, Fournier LS, Novikov VY, Shames DM, Roberts TP, Fu Y, Shalinsky DR, Brasch RC. Magnetic resonance imaging detects early changes in microvascular permeability in xenograft tumors after treatment with the matrix metalloprotease inhibitor prinomastat. Technol Cancer Res Treat. 3(4):377-82 (2004)

Kubota M, Ferrari P, Roberts TPL, Human neuronal encoding of English syntactic violations as revealed by both L1 and L2 speakers. Neurosci Lett. 368(2):235-40 (2004)

Preda A, Novikov V, Moglich M, Turetschek K, Shames DM, Brasch RC, Cavagna FM, Roberts TP. MRI monitoring of Avastin™ antiangiogenesis therapy using B22956/1, a new blood pool contrast agent, in an experimental model of human cancer. J Magn Reson Imaging. 20(5):865-873 (2004)

2003

Gage N, Siegel B, Callen M, Roberts TPL, Cortical Sound Processing in Children with Autism Disorder: An MEG Investigation. Neuroreport, 14:2047-2051 (2003)

Gage N, Siegel B, Roberts TPL, Cortical Auditory System Maturational Abnormalities in Children with Autism Disorder: An MEG Investigation. Dev Brain Res, 144:201-209 (2003)

Martin A, Weber, O, Saeed M, Roberts TPL, Steady-state imaging for visualization of endovascular interventions. Magn. Reson. Med 50: 434-438 (2003)

Inouchi M, Kubota M, Ferrari P, Roberts TPL, Magnetic mismatch fields elicited by vowel duration and pitch changes in Japanese words in humans: comparison between native- and non-speakers of Japanese. Neurosci Lett 353:165-8 (2003)

Kubota M, Ferrari P, Roberts TPL, Magnetoencephalography detection of early syntactic processing in humans: comparison between L1 speakers and L2 learners of English. Neurosci Lett 353:107-110 (2003)

Burn PR, Haider MA, Alfuhaid T, Brown MP, Roberts TPL, Proton magnetic resonance spectroscopy as a potential tool for differentiating between abdominal fluid collections. J Magn Reson Imag 18:740-4 (2003)

Disbrow EA, Hinkley L, Roberts TPL, Ipsilateral representation of oral structures in human anterior parietal somatosensory cortex and integration of inputs across the midline.J Comp Neurol 467:487-95 (2003)

McKenzie AL, Nagarajan SS, Roberts TPL, Merzenich M, Byl NN, Somatosensory representation of the digits and clinical performance in patients with focal hand dystonia. Am J Phys Med Rehabil. 82(10):737-49 (2003)

Schiffbauer H, Berger MS, Ferrari P, Freudenstein D, Rowley HA, Roberts TPL. Preoperative magnetic source imaging for brain tumor surgery: a quantitative comparison with intraoperative sensory and motor mapping. J Neurosurg. 2002 Dec; 97(6):1333-42. Reprinted in Neurosurg Focus. 2003 Jul 15; 15(1):E7.

Roberts TPL, Rowley HA. Diffusion weighted imaging in stroke. Eur. J. Radiol. 45:185-194 (2003)

Weiss WA, Burns MJ, Hackett C, Aldape K, Hill JR, Kuriyama H, Kuriyama N, Milshteyn N, Roberts T, Wendland MF, DePinho R, Israel MA. Genetic determinants of malignancy in a mouse model for oligodendroglioma. Cancer Res. 2003; 63(7):1589-95.

Turetschek K, Preda A, Floyd E, Shames DM, Novikov V, Roberts TP, Wood JM, Fu Y, Carter WO, Brasch RC. MRI monitoring of tumor response following angiogenesis inhibition in an experimental human breast cancer model. Eur J Nucl Med Mol Imaging 30(3):448-55 (2003)

Tang L, Mantle M, Ferrari P, Schiffbauer H, Rowley HA, Barbaro NM, Berger MS, Roberts TP. Consistency of interictal and ictal onset localization using magnetoencephalography in patients with partial epilepsy. J Neurosurg 98(4):837-45 (2003)

Koyama S, Akahane-Yamada R, Gunji A, Kubo R, Roberts TP, Yabe H, Kakigi R. Cortical evidence of the perceptual backward masking effect on /l/ and /r/ sounds from a following vowel in japanese speakers. Neuroimage 18(4):962-74 (2003)

2002

Byl NN, Nagarajan SS, Merzenich MM, Roberts T, McKenzie A. Correlation of clinical neuromusculoskeletal and central somatosensory performance: variability in controls and patients with severe and mild focal hand dystonia. Neural Plast 9(3):177-203 (2002)

Roberts HC, Roberts TPL, Lee TY, Dillon WP, Dynamic, contrast-enhanced CT in human brain tumors: quantitative assessment of blood volume, blood flow, and microvascular permeability, AJNR Am J Neuroradiol, 23: 828-832 (2002)

Roberts TPL, Tran Q, Ferrari P, Berger M. Increased Somatosensory Neuromagnetic Fields ipsilateral to lesions in neurosurgical patients, Neuroreport, 13:699-702 (2002)

Gossmann A, Helbich TH, Kuriyama N, Ostrowitzki S, Roberts TP, Shames DM, van Bruggen N, Wendland MF, Israel MA, Brasch RC. Dynamic contrast-enhanced magnetic resonance imaging as a surrogate marker of tumor response to anti-angiogenic therapy in a xenograft model of glioblastoma multiforme. J Magn Reson Imaging. 2002; 15(3):233-40.

Inouchi M, Kubota M, Ferrari P, Roberts TPL. Neuromagnetic auditory cortex responses to duration and pitch changes in tones:  cross-linguistic comparisons of human subjects in directions of acoustic changes. Neurosci Lett, 2002; 331: 138-141

Roberts TP, Helbich TH, Ley S, Turetschek K, Wendland MF, Shames DM, Brasch RC. Utility (or not) of Gd-DTPA-based dynamic MRI for breast cancer diagnosis and grading. Acad Radiol. 2002;9 Suppl 1:S261-5.

van Dijke CF, Mann JS, Rosenau W, Wendland MF, Roberts TP, Roberts HC, Demsar F, Brasch RC. Comparison of MR contrast-enhancing properties of albumin-(biotin)10-(gadopentetate)25, a macromolecular MR blood pool contrast agent, and its microscopic distribution. Acad Radiol. 2002;9 Suppl 1:S257-60.

Roberts HC, Roberts TP, Ley S, Dillon WP, Brasch RC. Quantitative estimation of microvascular permeability in human brain tumors: correlation of dynamic Gd-DTPA-enhanced MR imaging with histopathologic grading. Acad Radiol. 2002;9 Suppl 1:S151-5.

Helbich TH, Roberts TP, Rollins MD, Shames DM, Turetschek K, Hopf HW, Muhler M, Hunt TK, Brasch RC. Noninvasive assessment of wound-healing angiogenesis with contrast-enhanced MRI. Acad Radiol. 2002;9 Suppl 1:S145-7.

Turetschek K, Huber S, Helbich T, Floyd E, Tarlo KS, Roberts TP, Shames DM, Wendland MF, Brasch RC. Dynamic MRI enhanced with albumin-(Gd-DTPA)30 or ultrasmall superparamagnetic iron oxide particles (NC100150 injection) for the measurement of microvessel permeability in experimental breast tumors. Acad Radiol. 2002;9 Suppl 1:S112-4.

Tada T, Wendland M, Watson N, Kuriyama N, Kuriyama H, Roberts T, Burns M, Weiss W, Israel MA. A head holder for magnetic resonance imaging that allows the stereotaxic alignment of spontaneously occurring intracranial mouse tumors. J Neurosci Methods. 2002;116(1):1-7.

Roberts HC, Roberts TP, Lee TY, Dillon WP. Dynamic, Contrast-Enhanced CT of Human Brain Tumors: Quantitative Assessment of Blood Volume, Blood Flow, and Microvascular Permeability: Report of Two Cases. AJNR Am J Neuroradiol. 2002; 23(5):828-32.

Gage NM, Roberts TP, Hickok G. Hemispheric asymmetries in auditory evoked neuromagnetic fields in response to place of articulation contrasts. Cog. Brain Res. 2002: 14: 303-306

Inouchi M, Kubota M, Roberts TPL. Magnetoencephalography evidence of semantic violations in auditory sentence comprehension by native speakers of Japanese. Neurosci Lett. 2002; 331:133-6

Vates GE, Lawton MT, Wilson CB, McDermott MW, Halbach VV, Roberts TP, Rowley HA. Magnetic source imaging demonstrates altered cortical distribution of function in patients with arteriovenous malformations. Neurosurgery. 2002; 51(3):614-27.

Turetschek K, Preda A, Floyd E, Shames DM, Novikov V, Roberts TP, Wood JM, Fu Y, Carter WO, Brasch RC. MRI monitoring of tumor response to a novel VEGF tyrosine kinase inhibitor in an experimental breast cancer model. Acad Radiol. 2002 9 Suppl 2:S519-20.

Roberts TPL, Turetschek K, Preda A, Novikov V, Moeglich M, Shames DM, Brasch RC, Weinmann HJ. Tumor microvascular changes to anti-angiogenic treatment assessed by MR contrast media of different molecular weights. Acad Radiol. 2002;9 Suppl 2:S511-3

Jiang Y, Zhao JJ, Tang H, Wendland MF, Roberts TP, Lauffer RB, Genant HK. MRI of antigen-induced arthritis in rabbits: improved contrast and disease characterization with the blood pool agent MS-325. Acad Radiol. 2002;9 Suppl 2:S480.

Roberts HC, Roberts TP, Lee TY, Dillon WP. Dynamic contrast-enhanced computed tomography (CT) for quantitative estimation of microvascular permeability in human brain tumors. Acad Radiol. 2002 Aug;9 Suppl 2:S364-7.

Daldrup-Link HE, Kaiser A, Link TM, Settles M, Helbich T, Werner M, Roberts TP, Rummeny EJ. Comparison between gadopentetate and feruglose (Clariscan)-enhanced MR-mammography: preliminary clinical experience. Acad Radiol. 2002;9 Suppl 2:S343-7.

Brasch RC, Gossmann A, Helbich TH, Kuriyama N, Roberts TP, Shames DM, van Bruggen N, Wendland MF, Israel MA.  Can a small-molecular gadolinium contrast agent be applied successfully with dynamic MRI to quantitatively define brain tumor microvascular responses to angiogenesis inhibition? Acad Radiol. 2002;9 Supp 2:S326-7.

Weiss WA, Israel M, Cobbs C, Holland E, James CD, Louis DN, Marks C, McClatchey AI, Roberts T, Van Dyke T, Wetmore C, Chiu IM, Giovannini M, Guha A, Higgins RJ, Marino S, Radovanovic I, Reilly K, Aldape K. Neuropathology of genetically engineered mice: consensus report and recommendations from an international forum. Oncogene 2002; 21: 7453-7463

Wilson MW, LaBerge JM, Kerlan RK, Martin AJ, Weber OM, Roberts T, Vitalich C, Higgins CB, Gordon RL. MR portal venography: preliminary results of fast acquisition without contrast material or breath holding. Acad Radiol 2002; 9: 1179-1184

Roberts TPL, Hassenzahl W, Hetts S, Arenson RL. Remote control of catheter tip deflection: An opportunity for interventional MRI. Magn Reson Med. 2002; 48(6):1091-5.

2001

Szymanksi MD, Perry DW, Roberts TPL, Gage NM, Rowley HA, Walker J, Berger MS. Magnetic source imaging of late-evoked field responses to vowels: toward an assessment of hemispheric dominance for language J. Neurosurg. 94:445-453 (2001)

Disbrow E, Roberts T, Poeppel D, Krubitzer L. Evidence for interhemispheric processing of inputs from the hands in human S2 and PV. J Neurophysiol. 85(5):2236-44 (2001)

Roberts HC, Roberts TPL, Bollen AW, Ley S, Brasch RC, Dillon WP. Correlation of microvascular permeability derived from dynamic contrast-enhanced MR imaging with histologic grade and tumor labeling index: a study in human brain tumors. Acad Radiol. 8(5):384-91 (2001)

Turetschek K, Floyd E, Shames DM, Roberts TPL, Preda A, Novikov V, Corot C, Carter WO, Brasch RC. Assessment of a rapid clearance blood pool MR contrast medium (P792) for assays of microvascular characteristics in experimental breast tumors with correlations to histopathology. Magn Reson Med. 45(5):880-6 (2001)

Turetschek K, Roberts TPL, Floyd E, Preda A, Novikov V, Shames DM, Carter WO, Brasch RC, Tumor microvascular characterization using ultrasmall superparamagnetic iron oxide (USPIO) particles in an experimental breast cancer model. J Magn Reson Imag 13(6):882-8. (2001)

Roberts HC, Roberts TPL, Dillon, WP. CT perfusion: “off and running” or “up and coming” ?, AJNR Am J Neuroradiol 22:1018-1019 (2001)

Roberts HC, Roberts TPL, Smith WS, Lee TJ, Fischbein NJ, Dillon WP. Multisection dynamic CT perfusion for acute cerebral ischemia: the "toggling-table" technique. AJNR Am J Neuroradiol 22(6):1077-80 (2001)

Prayer D, Barkovich AJ, Kirschner DA, Prayer LM, Roberts TPL, Kucharczyk J, Moseley ME. Visualization of non-structural changes in early white matter development by diffusion-weighted MR imaging: evidence supporting premyelination anisotropy. AJNR Am J Neuroradiol. 22:1572-1576 (2001)

Schiffbauer H, Ferrari P, Rowley HA, Berger MS, Roberts TPL, Functional Activity within Brain Tumors: A Magnetic Source Imaging Study. Neurosurgery. 49:1313-1321 (2001)

Turetschek K, Huber S, Floyd E, Helbich T, Roberts TP, Shames DM, Tarlo KS, Wendland MF, Brasch RC. MR Imaging Characterization of Microvessels in Experimental Breast Tumors by Using a Particulate Contrast Agent with Histopathologic Correlation. Radiology 218(2):562-569 (2001)

2000

Helbich T, Roberts TPL, Gossmann A, Wendland MF, Shames DM, Adachi M, Yang S, Huber S, Daldrup H, Brasch RC, "Quantitative gadopentetate-enhanced MR imaging of breast tumors: testing of different analytic methods", Magn.Reson.Med. 44(6):915-24 (2000)

Roberts TPL, A. Martin, Dillon WP, R.L. Arenson and C.B. Higgins Integrating X-ray angiography and MRI for endovascular interventions, MedicaMundi 44:2-9 (2000)

Stufflebeam S, Poeppel D, Roberts TPL Temporal encoding in auditory evoked neuromagnetic fields: stochastic resonance, Neuroreport, 11(18):4081-5 (2000)

Derugin N, Wendland M, Muramatsu K, Roberts TPL, Gregory G, Ferriero DM, Vexler ZS. Evolution of brain injury after transient middle cerebral artery occlusion in neonatal rat brain. Stroke, 31(7):1752-1761 (2000)

Baron R, Baron Y, Disbrow E, Roberts TPL. Activation of the somatosensory cortex during A-fiber mediated hyperalgesia -an MSI study, Brain Res., 871(1):75-82 (2000)

Roberts TPL, Disbrow E, Roberts HC, Rowley HA, Quantification and reproducibility of cortical extent of activation with fMRI and MEG, AJNR Am. J. Neuroradiol. 21:1377-1387 (2000)

Roberts HC, Roberts TPL, Brasch RC, Dillon WP, Quantitative Estimation of Microvascular Permeability in Human Brain Tumors: Correlation with Histopathological Grade, AJNR Am. J. Neuroradiol, 21(5): 891-899 (2000)

Roberts TPL, Ferrari P, Stufflebeam S., Poeppel D, Latency of the auditory evoked neuromagnetic field components – Stimulus dependence and insights towards perception, J. Clin. Neurophysiol. 17(2):114-129 (2000)

Helbich T, Gossmann A, Mareski PA, Radüchel B, Roberts TPL, Shames DM, Mühler M, Turetschek K, Brasch RC. A new polysaccharide macromolecular contrast agent for MR imaging: biodistribution and imaging characteristics. J Mag Reson Imag 11: 694-701 (2000)

Roberts TPL, Chuang N, Roberts HC, Neuroimaging: do we really need new contrast agents for MRI?, Eur. J. Radiol., 34:166-178 (2000)

Gage N, Roberts TPL, Temporal Integration: Reflections in the M100 of the auditory Evoked Field, Neuroreport, 11(12):2723-2726 (2000)

Fischbein NJ, Roberts TPL, Dillon WP, Bleed or stroke? Diffusion measurements in intracranial hematomas. AJNR Am J Neuroradiol 21(7):1179-80 (2000)

Disbrow EA, Slutsky D, Roberts TPL, Krubitzer LA, Functional MRI at 1.5 Tesla: A comparison of the blood oxygenation level-dependent signal and electrophysiology. Proc Natl Acad Sci U S A 97(17):9718-23 (2000)

Gossmann A, Helbich T, S. Mesiano, Shames DM, M.F. Wendland, T.P. L. Roberts, N. Ferrara, R.B. Jaffe, Brasch RC. Magnetic resonance imaging in ovarian cancer demonstrating altered microvascular permeability following inhibition of vascular endothelial growth factor. J.Ob.Gyn. 183(4):956-63 (2000)

Le TH, Patel S, Roberts TPL. Functional MRI of Human Auditory Cortex Using Block and Event-Related Designs. Magn Reson Med, 45:254-260 (2001)

Phillips C, Marantz A, Poeppel D, Yellin E, McGinnis M, Roberts TPL, Rowley HA, "Auditory Cortex Accesses Phonological Categories: An MEG Mismatch Study", J. Cogn. Neurosci., 12: 1038-1055 (2000)

Roberts TPL, Ferrari P, Perry D, Rowley HA, Berger MS, Presurgical Mapping with Magnetic Source Imaging: Comparisons with Intra-Operative Findings. Brain Tumor Pathology, 17:57-64 (2000)

Disbrow E, Roberts TPL, Krubitzer L, "The somatotopic organization of areas in the lateral sulcus in homo sapiens", J. Comp Neurol, 418:1-21 (2000)

Bremerich J, Roberts TPL, Reddy G, Wendland MF, Wyttenbach R, Arheden H, Shafaghi N, Higgins CB, Saeed M, "Three-dimensional MR imaging of pulmonary vessels and parenchyma with NC100150 Injection (Clariscan TM), J.Magn.Reson. Imaging, 11: 622-628 (2000)

1999

Baron R, Baron Y, Disbrow E, Roberts TPL, Brain processing of capsaicin-induced secondary hyperalgesia: a functional MRI study. Neurology, 53(3):548-57 (1999)

Disbrow E, Roberts TPL, Slutsky D, Krubitzer L, The use of fMRI for determining the topographic organization of cortical fields in human and non-human primates. Brain Res. 829: 167-173 (1999)

VanDijke CF, Peterfy CG, Brasch RC, Lang O, Roberts TPL, Shames D, Kneeland JB, Lu Y, Mann JS, Kapila S, Genant HK, MR imaging of the arthritic rabbit knee joint using albumin-(GdDTPA)30 with correlation to histopathology, Mag Res Imag 17: 237-245 (1999)

Dillon WP, Roberts TPL, "Limitation of fMRI: Caveat", Am. J. Neuroradiol. , 20: 536 (1999)

Wittlinger T, Voigtlander T, Roberts H, Kreitner KF, Roberts T, Nixdorff U, Oelert H, Thelen M, Meyer J. Diagnosis of an intramyocardial hematoma via MRI after a traumatic myocardial infarct. Zeitschrift Fur Kardiologie, 88(2):147-153 (1999).

Szymanski MD, Rowley HA, Roberts TPL. A hemisperically asymmetrical MEG response to vowels, Neuroreport, 10(12): 2481-2486 (1999)

Nagarajan S, Mahncke H, Salz T, Tallal P, Roberts T, Merzenich MM. Cortical auditory signal processing in poor readers, Proc Natl Acad Sci USA 96: 6483-6488 (1999)

Stiskal M, Demsar F, Mühler A, Schwickert HC, Roberts TPL, Szolar D, Fischer H, Brasch RC. Contrast-enhanced MR imaging of two superparamagnetic RES-contrast agents: functional assessment of experimental radiation-induced liver injury. JMRI 10:52-56 (1999)

Eberle B, Weiler N, Markstaller K, Surkau R, Kauczor HU, Schreiber W, Roberts TPL, Heinrichs W, Otten EW, Thelen M, "Analysis of regional intrapulmonary O2 concentrations by magnetic resonance imaging of inhaled hyperpolarized 3-Helium", J. Appl. Physiol. 87(6):2043-52 (1999)

Okuhata Y, Brasch RC, Pham CD, Daldrup H, Wendland MF, Shames DM, Roberts TPL, "Tumor blood volume assays using contrast-enhanced MRI: regional heterogeneity and post-mortem artifacts", JMRI, 9: 685-690 (1999)

Gossmann A, Okuhata Y, Shames DM, Helbich T, Roberts TPL, Wendland MF, Huber S, Brasch RC, "Prostate cancer tumor grade differentiation by dynamic contrast-enhanced MR imaging: comparison of macromolecular and small-molecular contrast media", Radiology 213:265-272 (1999)

Roberts HC, Saeed M, Roberts TPL, Mühler A, Brasch RC, "MR Imaging of acute myocardial ischemia: comparing a new macromolecular contrast agent, GdDTPA-24-Cascade-Polymer, with GdDTPA, JMRI, 9: 204-208 (1999)

1998

Gage N, Poeppel D, Roberts TPL, Hickok G, "Auditory evoked M100 reflects onset acoustics of speech sounds", Brain Res. 814: 236-239(1998)

Wittlinger T, Voigtländer T, Roberts H, Kreitner KF, Roberts TPL et al.: Acute coronary artery perforation after percutaneous transluminal angioplasty with shunt in the right ventricle. Zeitschrift für Kardiologie 87 :553-559 (1998)

Demsar F, Shames DM, Roberts TPL, Stiskal M, Roberts H, et al.: Kinetics of MRI contrast agents with a size ranging between Gd-DTPA and albumin-Gd-DTPA: Use of cascade-Gd-DTPA-24 polymer. Electro- and magnetobiology 17: 283-297: (1998)

Kalden P, Kreitner KF, Voigtländer T, Roberts H, Roberts TPL, Krummenauer F, Becker D, Wittlinger T, Meyer J, Thelen M: Flußquantifizierung von intrakardialen Shuntvolumina unter Verwendung der MR-Phasenkontrast-Technik in Atemanhaltephase. Fortschr. Röntgenstr. 169: 378-382 (1998)

Roberts TPL, "Information encoding in temporal aspects of electromagnetic fields consequent to human cortical neuronal activation ", J. Biochem Bioenergetics, 47: 265-271 (1998)

Roberts TPL, Poeppel D, Rowley HA, "Magnetoencephalography And Functional MRI : A Quantitative Study Of Speech Perception ", Proc. IEEE Eng. Med & Biol. Soc., 20(4): 2120-2123 (1998)

Kauczor HU, Surkau R, Roberts TPL, "MRI using Hyperpolarized Noble Gases", European Radiology, 8: 820-827 (1998)

Roberts HC, Saeed M, Roberts TPL, Brasch RC, "MR Imaging of acute myocardial ischemia and reperfused myocardiual inmfarction: comparing a new macromolecular contrast agent, GdDTPA-24-Cascade-Polymer, with GdDTPA", Acad Radiol., 5(1) : S31-33 (1998)

Roberts TPL, Roberts HC, Brasch RC, "Optimizing imaging techniques to reduce errors in microvascular quantitation with macromolecular contrast agents", Acad Radiol., 5(1): S133-136 (1998)

Roberts TPL, Ferrari P, Poeppel D, "Latency of Evoked Neuromagnetic M100 Reflects Perceptual and Acoustic Stimulus Attributes", Neuroreport, 9: 3265-3269 (1998)

Roberts TPL, "Information encoding in the temporal characteristics of auditory evoked neuromagnetic fields", SPIE, 3337:210-219 (1998)

Stufflebeam SM, Poeppel D, Rowley HA, Roberts TPL, "Encoding of stimulus frequency and intensity in the M100 latency near hearing threshold", Neuroreport, 9:91-95 (1998)

Ostrowitzki S, Fick J, Roberts TPL, Brasch RC, "Comparison of GdDTPA with Albumin-GdDTPA30 for the microvascular characterization of 9L-Glioma in the rat", JMRI, 8: 799-806 (1998)

Pham CD, Roberts TPL, van Bruggen N, Melnyk O, Mann J, Ferrara N, Cohen RL, Brasch RC "Magnetic resonance imaging detects suppression of tumor vascular permeability after administration of antibody to vascular endothelial growth factor", Cancer Invest, 1998;16(4):225-30

Roberts TPL, Poeppel D, Rowley HA, "Magnetoencephalography and Magnetic Source Imaging", Neuropsychiatry, Neuropsychology and Behavioral Neurology, 11(2): 49-64 (1998)

1997

Daldrup H, Roberts TPL, Mühler A, Gossmann A, Roberts HC, Wendland M, Rosenau W, Brasch RC, "Makromolekulare Kontrastmittel für die MR-Mammographie: Ein neuer Ansatz für die Charakterisierung von Mamma-Tumoren", Der Radiologe, 37:733-740 (1997)

Poeppel D, Roberts TPL, "Effects of Vowel Pitch and Task Demands on Latency and Amplitude of the Auditory Evoked M100", Brain and Cognition. 32 (2) : 156-158 (1996)

Roberts TPL "Physiologic Measurements by Contrast Enhanced MRI : Expectations and Limitations", JMRI, 7(1):82-90 (1997)

Spengler F, Roberts TPL, Poeppel D, Byl N, Rowley HA, Merzenich M. "MSI of cortical plasticity induced by somatosensory training", Neurosci Lett, 232:151-154 (1997)

Poeppel D, Phillips C, Yellin E, Rowley HA, Roberts TPL, Marantz A, "Processing of vowels in supratemporal cortex", Neurosci Lett, 221: 145-148 (1997)

Knowlton R, Roberts TPL, Wong STC, Aminoff MJ, Laxer KD, Rowley HA, "Relationship of magnetoencephalographic spike sources and localization of epileptogenic substrates", Ann Neurol, 42:622-631 (1997)

Hickok G, Poeppel D, Clark K, Buxton R, Rowley HA, Roberts TPL, "Visual and somatosensory mapping in a congenitally deaf subject: MEG and fMRI investigations of cross-modality plasticity", Human Brain Mapping, 5:437-444 (1997)

Kauczor HU, Ebert M, Kreitner KF, Grossmann T, Nilgens H, Hofmann D, Surkau R, Roberts TPL, Otten E, Thelen M, The helium-3 MRI of pulmonary ventilation: the initial clinical applications", Fortschr. Roentgen, 166(3):192-198(1997)

Brasch RC, Pham C, Shames D, Roberts TPL, VanDijke CF, vanBruggen N, Mann J, Ostrowitski S, Melnyp O, "Assessing tumor angiogenesis using macromolecular contrast media", JMRI, 7(1): 68-74 (1997)

Roberts TPL, Rowley HA, "Mapping of the Sensorimotor Cortex: Functional MR and Magnetic Source Imaging", Am J Neurorad, 18:871-880 (1997)

Demsar F, Roberts TPL, Schwickert HC, Shames DM, vanDijke CF, Mann JS, Saeed M, Brasch RC, A MRI spatial mapping technique for microvascular permeability and tissue blood volume based on macromolecular contrast agent distribution, Magn.Reson.Med., 37: 236-242 (1997)

Prayer D, Roberts TPL, Barkovich AJ, Prayer L, Kucharczyk J, Moseley M, Arieff A, "Diffusion weighted MRI of rat brain myelination following treatment with gonadal hormones", Neuroradiology , 39:320-325 (1997)

Roberts HC, Saeed M, Roberts TPL, Mühler A, Shames DM, Stiskal M, Demsar F, Brasch RC, "Comparison of albumin-GdDTPA30 and GdDTPA-24-cascade polymer for quantification of normal and abnormal microvascular permeability, JMRI, 7(2): 331-338 (1997)

Vexler ZS, Roberts TPL, Bollen AW, Derugin N, Arieff A, "Reperfusion ischemic injury: induction of apoptotic cell death depends on the degree of hypoperfusion", J Clin Invest, 99:1-7 (1997)

1996

Demsar F, VanDijke CF, Kirk BA, Kapila S, Peterfy CG, Roberts TPL, Shames DM, Tomazic S, Mann J, Brasch RC, "Mapping abnormal synovial vascular permeability in temporomandibular joint arthritis in the rabbit using MRI", Br. J. Rheumatol. 35(3): 23-25 (1996)

Demsar F, Roberts TPL, Schwickert HC, Shames DM, Mann J, Tomazic S, Brasch RC, "MRI mapping of microvascular permeability and tissue blood volume", Eur. J. Physiol. 431:R263-4 (1996)

McDonald A, Roberts TPL, Rowley HA, Pogrel MA, "Noninvasive somatosensory monitoring of the injured inferior alveolar nerve using magnetic source imaging", J.Oral Maxillofacial Surg., 54(9):1068-1072 (1996)

Siedenberg R, Goodin DS, Aminoff MJ, Rowley HA, Roberts TPL, "Localizing dipoles: the correlation coefficient and the goodness of fit in source localization of noise recorded with magnetoencephalography", Brain Topogr, 9: 95-100 (1996)

Poeppel D, Yellin E, Phillips C, Roberts TPL, Rowley HA, Wexler K, Marantz A, "Hemispheric symmetry and asymmetry of the auditory evoked M100 neuromagnetic field elicited by speech sounds", Cogn. Brain Res. : 231-242 (1996)

Szolar D, Saeed M, Wendland MF, Sakuma H, Roberts TPL, Stiskal M, Derugin N, Higgins CB, "MR Imaging Characterization of Postischemic Myocardial Dysfunction ("Stunned Myocardium") : Relationship between Functional and Perfusion Abnormalities" JMRI , 6: 615-624 (1996)

Schmidt HC, Brasch RC, Roberts TPL, Shames DM, vanDijke CF, Stiskal M, Mann JS, Mühler A, Demsar F, Time and dose dependency of radiation-induced changes in tumor microvascular characteristics using contrast-enhanced MRI: impact on delivery of chemotherapy, Acad Radiol, 3:S347-348 (1996)

Brasch RC, Schwickert HC, Roberts TPL, Shames DM, vanDijke CF, Mann JS, Demsar F, "Definition of peritumoral vessels with contrast enhanced magnetic resonance imaging", Acad Radiol, 3: S464-465 (1996)

Roberts TPL, Brasch RC, Schwickert HC, Shames DM, vanDijke CF, Stiskal M, Mann JS, Mühler A, Demsar F, Quantification of tissue gadolinium concentration using MRI: comparison of ultra short TI inversion recovery (ULSTIR) echo planar and dynamic 3D-SPGR approaches with in-vitro measurements, Acad Radiol, 3: S282-285 (1996)

Demsar F, Roberts TPL, Schwickert HC, vanDijke CF, Shames DM, Peterfy C, Kapila SD, Brasch RC, MRI mapping of tissue permeability and blood volume based on contrast enhancement using a blood pool agent, Acad Radiol, 3: S344-346 (1996)

Siedenberg R, Goodin DS, Aminoff MJ, Rowley HA, Roberts TPL, "Comparison of late components in simultaneously recorded event-related electrical potentials and event-related magnetic fields", EEG & Clin.Neurophysiol., 99: 191-197 (1996)

Vexler VS, Roberts TPL, Rosenau W, "Diffusion-Weighted Magnetic Resonance Imaging Of Acute Tubular Necrosis In A Rat Model", Renal Failure 18(1):41-57.(1996)

Schwickert HC, Stiskal M, Roberts TPL, vanDijke CF, Mann J, Mühler A, Shames DM, Demsar F, Brasch RC, "Contrast-enhanced MRI Assessment of Tumor Capillary Permeability: The Effect of Pre-irradiation on the Tumor Delivery of Chemotherapy", Radiology, 198: 893-898 (1996)

Miller AD, Rowley HA, Roberts TPL, Kucharczyk J. Human cortical activity during vestibular- and drug-induced nausea detected using MSI. In: New Directions in Vestibular Research, Highstein SM, Cohen B, Buttner-Ennever JA (eds), Annals of the New York Academy of Sciences 781;670-672 (1996)

Stiskal M, Schwickert HC, Demsar F, Roberts TPL, Szolar D, Weissleder R, Brasch RC, "Contrast-enhancement in experimental radiation-induced liver injury: comparison of hepatocellular and reticuloendothelial particulate contrast agents", JMRI, 6:286-290, (1996)

VanDijke CF, Brasch RC, Roberts TPL, Weidner N, Mathur A, Shames DM, Mann JS, Demsar F, Lang P, Schwickert HC, "Correlation of MRI microvascular characterizations using a blood pool contrast medium and histologic capillary densities in a mammary carcinoma model", Radiology, 198: 813-818 (1996)

Roberts TPL, Poeppel D, "Latency of auditory evoked M100 as a function of tone frequency", Neuro Report, 7: 1138-1140 (1996)

Roberts TPL, Vexler ZS, Vexler V, Derugin N, Kucharczyk J, "Sensitivity of High-Speed 'Perfusion' MRI to Mild Cerebral Ischemia", Eur Radiol, 6: 645-649 (1996)

1995

Roberts TPL, Zusman E, Barbaro N, McDermott M, Rowley HA, "Correlation of Functional Magnetic Source Imaging with Intra-operative Cortical Stimulation in Neurosurgical Patients", J.Image Guided Surgery, 1(6):339-347 (1995)

* Wimberger D, Roberts TPL, Barkovich AJ, Prayer L, Moseley ME, Kucharczyk J, "MRI Detection of White Matter Maturation before Myelination", J Comp Assist Tomogr, 19(1), 28-33 (1995)

Arieff AI, Kozniewska E, Roberts TPL, Vexler ZS, Ayus JC, Kucharczyk J, "Brain Damage in Experimental Metabolic Encephalopathy is a Function of Age and Gender", Am.J.Physiol. 37:R1143-R1152 (1995)

Kozniewska E, Roberts TPL, Oseka M, Vexler ZS, Kucharczyk J, Arieff AI, "Hormonal Dependence of the Effect of Chronic Hyponatremia on Cerebral Perfusion and Oxygen Utilization in the Rat", Circulation Res., 76:551-558 (1995)

Kozniewska E, Roberts TPL, Tsuura M, Mintorovitch J, Moseley ME, Kucharczyk J, "NG-Nitro-L-Arginine Delays the Development of Brain Injury during Focal Ischemia in the Rat", Stroke, 26:282-288 (1995)

Roberts TPL, Vexler ZS, Derugin N, Kozniewska E, Kucharczyk J, Emmett C, "MRI Evaluation of a Putative Cerebroprotective Agent, Recombinant Human Basic Fibroblast Growth Factor, rhbFGF", Brain Res., 699; 51-61 (1995)

Genain CP, Roberts TPL, Davis RL, Nguyen MH, Uccelli A, Faulds D, Hoffman K, Timmel GB, Li Y, Ferrante R, Joshi N, Hedgpeth J, Hauser S, "Prevention of Autoimmune Demyelination in Non-Human Primates by a Type IV Phosphodiesterase Inhibitor", Proc Nat Acad Sci USA, 92:3601-3605 (1995)

Roberts TPL, "Medical magnetic source imaging", IEEE Wescon, 679-683, (1995)

Schwickert HC, Roberts TPL, Shames D, van Dijke CF, Disston A, Mühler A, Mann JS, Brasch RC, "Quantification of Liver Blood Volume: Comparison of ULSTIR-EPI, a Fast Inversion Recovery Echo Planar Approach with Dynamic 3D-SPGR", Magn.Reson.Med., 34:845-852 (1995)

Schwickert HC, Roberts TPL, Mühler A, Stiskal M, Demsar F, Brasch RC, "Angiographic Properties of Gd-DTPA-24-Cascade Polymer - A New Macromolecular MR Contrast Agent", Eur J Radiol, 20:144-150 (1995)

Schwickert HC, Stiskal M, vanDijke CF, Roberts TPL, Mann JS, Demsar F, Brasch RC, "Tumor Angiography using High Resolution 3D MRI: Comparison of Gd-DTPA and a Macromolecular Blood Pool Contrast Agent", Acad Radiol, 2(10): 851-858 (1995)

Lang P, Honda G, Roberts TPL, Vahlensieck M, Johnston JO, Rosenau W, Mathur A, Peterfy C, Gooding CA, Genant H, "Musculoskeletal neoplasm: perineoplastic edema versus tumor on dynamic postcontrast MR images with spatial mapping of instantaneous enhancement rates" , Radiology, 197:831-839 (1995)

1994

Vexler ZS, Ayus JC, Roberts TPL, Kucharczyk J, Arieff AI, "Hypoxia Exacerbates Brain Injury Associated with Metabolic Encephalopathy", J. Clin. Invest., 93, 256-264 (1994)

Derugin N, Roberts TPL, "A New and Reproducible Technique for Experimentally Induced Middle Cerebral Artery Stenosis", Microsurgery, 15, 70-72 (1994)

Vexler ZS, Roberts TPL, Kucharczyk J, Arieff A, "Severe Brain Edema Associated with Cumulative Effects of Hyponatremic Encephalopathy and Hypoxic Ischemia", Acta Neurochirurgica Suppl. 60, 246-249, Springer Verlag (1994)

Vexler ZS, Roberts TPL, Derugin N, Kozniewska E, Arieff A, Kucharczyk J, "Mechanisms of the Brain Injury Associated with Partial and Complete Occlusion of the MCA in Cat", Acta Neurochirurgica Suppl. 60, 211-215, Springer Verlag (1994)

Wendland MF, Saeed M, Yu KK, Roberts TPL, Lauerma K, Derugin N, Varadarajan J, Watson AD, Higgins CB, "Inversion Recovery EPI of Bolus Transit in Rat Myocardium using Intravascular and Extravascular Gadolinium-based MR Contrast Media: Dose Effects on Peak Signal Enhancements", Magn.Reson.Med., 32, 319-329 (1994)

Roberts TPL, Kucharczyk J, Cox I, Moseley ME, Prayer L, Dillon WP, Harnish P, "Sprodiamide Injection-Enhanced MR Imaging of Cerebral Perfusion: Phase I Clinical Trial Results", Inv.Rad. 29, S24-26 (1994)

van Bruggen N, Roberts TPL, Cremer JE, "The Application of Magnetic Resonance Imaging to the Study of Cerebral Ischemia", Cerebrovasc. Brain Metab. Rev., 6, 180-210 (1994)

1993

Roberts TPL, Carpenter TA, Hall LD, "A Simple Method for the Construction of 180 Refocusing Pulses for use in MRI", J Magn Reson, B 101, 78-82 (1993)

Roberts TPL, Vexler Z, Derugin N, Moseley ME, Kucharczyk J, "High Speed MR Imaging of Ischemic Brain Injury Following Partial Stenosis of the Middle Cerebral Artery", J.Cereb.Blood Flow Metab., 13, 940-946 (1993)

Kucharczyk J, Roberts TPL, Moseley ME, Watson A, "Applications of Contrast-Enhanced Perfusion-Sensitive MR Imaging in the Diagnosis of Cerebrovascular Disorders", JMRI 3(1), 241-246 (1993)

deCrespigny AJS, Roberts TPL, Kucharczyk J, Moseley ME, "Increased Sensitivity to Magnetic Susceptibility Contrast", Magnetic Resonance in Medicine, 30(1), 135-137 (1993)

Kucharczyk J, Vexler Z., Roberts TPL, Asgari HS, Mintorovitch J, Derugin N, Watson A, Moseley ME, "Echo-planar Perfusion-sensitive Imaging of Acute Cerebral Ischemia", Radiology, 188, 711-717 (1993)

Roberts TPL, Kozniewska E, Kucharczyk J, Arieff AI, "Perfusion Sensitive MRI of Hyponatremic Encephalopathy", in Microcirculatory Stasis in the Brain, Elsevier 377-383 (1993)

Moseley ME, deCrespigny AJS, Roberts TPL, Kozniewska E, Kucharczyk J, "Early Detection of Regional Cerebral Ischemia Using High-Speed MRI", Stroke , 24(12), 160-165 (1993)

1992

Gates ARC, Roberts TPL, Shah NJ, Carpenter TA, Hall LD, "Reduction of Flow Artifacts in Fast Gradient Recalled Echo Imaging by the Use of Prefocused Pulses", J Magn Reson, 96, 222-228 (1992)

Davies ES, Roberts TPL, Carpenter TA, Hall LD, Hall C, "Visualization of Viscous Fingering by Magnetic Resonance Imaging", J Magn Reson, 96, (1992)

Doran SJ, Attard JJ, Roberts TPL, Carpenter TA, Hall LD, "Consideration of Errors in the Acquisition and Processing of Quantitative M.R.I. Relaxation Data", J Magn Reson, 100, 101-122 (1992)

1991

Roberts TPL, Carpenter TA, Hall LD, "Elimination of Steady State Magnetization in Fast Gradient Recalled Echo Imaging by the Use of Prefocused Pulses", J Magn Reson, 91, 204-208 (1991)

Roberts TPL, Carpenter TA, Hall LD, "Multislice Inversion Recovery Determination of T1 using Optimized Pulses", J Magn Reson, 94, 160-164 (1991)

Fordham EJ, Roberts TPL, Carpenter TA, Hall LD, Maitland GC, Hall C, "N.M.R. Imaging of Simulated Voids in Cement Slurries", A.I.Ch.E. Journal, 37(12), 1895-1899 (1991)

Fordham EJ, Roberts TPL, Carpenter TA, Hall LD, Hall C, "Rapid Particle Transport in Porous Media Observed by Prefocused FLASH N.M.R. Imaging", A.I.Ch.E. Journal, 37(12), 1900-1903 (1991)

1990

Roberts TPL, Carpenter TA, Hall LD, "Design and Application of Radiofrequency Pulses by Simulated Annealing", J Magn Reson, 89, 595-604 (1990)

Roberts TPL, de Crespigny AJ, Carpenter TA, Hall LD, "Correction for the Effects of Non-Linearities in RF Transmission Systems", J Magn Reson, 90, 377-381 (1990).

Books

Schmidt GL, Roberts TPL. Second language research using magnetoencephalography,” in “Second Language Research”, Eds: Smith MS, Archibold J. Sage (2009)

Functional Neuroimaging, Neuroimaging Clinics of North America, Eds: Kucharcyk J, Roberts TPL, Moseley ME, Orrison W. Saunders 5(2) (1995)

Biomedical Imaging in Experimental Neuroscience, Eds: VanBruggen N, Roberts TPL. CRC Press (2002)

Perfusion, Topics in MRI: Guest Editor: Roberts TPL. Series editor: Atlas, S. LWW Press (2004) 4. “1.5 vs 3T”, Neuroimaging Clinics of North America, ED; Roberts TPL. Saunders (2006)

Chapters

1995

Roberts TPL, Rowley HA, Kucharcyk J "Applications of MSI in Presurgical Mapping", in Neuroimaging Clinics of North America, Eds: Kucharczyk, Roberts, Moseley, Orrison, Saunders (1995) 5(2):251-266.

Posters and Presentations

Invited Lectures

2017

Roberts TPL. ESPR 2017 Meeting, Davos, Switzerland, May 2017.

Roberts TPL. ISACM 2017 Conference, Sendai, Japan, May 2017.

Roberts TPL. IMFAR 2017 Conference, San Francisco, CA, May 2017.

Roberts TPL. ASNR 2017 Conference, Long Beach, CA, April 2017.

Roberts TPL. Mt. Sinai-CHOP Research Day, New York, NY, April 2017.

Roberts TPL. SFARI 2017 Science Meeting, New York, NY, April 2017.

Roberts TPL. Alberta Children’s Hospital Grand Rounds, Calgary, Alberta, Canada, March 2017.

2016

Roberts TPL. Advanced Pediatric Radiology Conference, St. Petersburg, Russia, October 2016.

Roberts TPL. International Symposium Conference on BioMag, Seoul Korea, October 2016.

Roberts TPL. NF Conference, Austin, TX, June 2016.

Roberts TPL. Annual BioMagnetism Meeting, Kanawa, Japan, June 2016.

Roberts TPL. NLM Family Foundation Meeting, Boston, MA, May 2016.

Roberts TPL. ISMRM 2016 Conference, Singapore, China, May 2016.

Roberts TPL. Peking University Lecture, Beijing, China, April 2016.

Roberts TPL. SFARI Annual Meeting, New York, NY, April 2016.

Roberts TPL. ASFNF 2016 Conference, Austin, TX, February 2016.

2015

Roberts TPL. ISACM 2015 Conference, Helsinki, Finland, June 2015.

Roberts TPL. Geisinger Autism Developmental Med. Institute, Lewisburg, PA, June 2015.

Roberts TPL. IMFAR Annual Meeting, Salt Lake City, UT, May 2015.

Roberts TPL. ASNR 53rd Annual Meeting, Chicago, IL, April 2015.

Roberts TPL. 2015 SFARI Annual Meeting, New York, NY, April 2015.

Roberts TPL. ASFNR Annual Meeting, Tuscan, AZ, March 2015.

Roberts TPL. Aachen Winter School Lecturing, Aachen, Germany, January 2015.

Awards and Honors

Honors and Awards

2007, ASNR – elected Senior Member

2005, ASFNR Outstanding Presentation Award (Dydak 1st author)

2005, AAPM Young Investigator Award (Settecase 1st author)

2005, Science Service Award from NAAR for grant proposal “Electrophysiological signatures: an endophenotype for autism”

2002, Canada Research Chair in Neuroimaging

1999, Poster Prize, ECR (Helbich 1st author)

1997, Young Investigator Award, URSI-IEEE Symposium on Electromagnetism in Medicine

1996 Poster prize, 77th Deutscher Röntgenkongress

1995, Editor's Excellence Award for Outstanding Scientific Research, (Journal of Computer Assisted Tomography)

Editorial and Academic Positions

Editorial Positions

2007-present, Guest Associate Editor, Medical Physics

Academic and Institutional Committees

2015-present, Faculty Research Advisory Committee
2012-present, Faculty Conflict of Interest
2012-present, Faculty Compliance Committee
2010-present, Conflict of Interest Committee
2008-present, IIPAC (intellectual property committee)
2005-present, Chair, Radiology Research Committee

Leadership and Memberships

Memberships in Professional Organizations

2005-present, International Society for Advancement of Clinical MEG
 - Member, Founding Executive Steering Committee
 - 2015-2017, Treasurer
2004-present, American Society of Functional Neuroradiology
 - Member, Executive Committee
2000-present, American Society for Neuroradiology
 - 2007-2010, 2015-present, Executive Committee
 - 2000-present, Scientific Program Committee
 - 2009-present, Research Scientist Committee
 - 2015-2016, Program Committee, Executive Committee
1988-present, International Society for Magnetic Resonance in Medicine