Reviewed by Shobha S. Natarajan, MD
What is aortic regurgitation?
When the heart squeezes, the heart’s lower left chamber (or left ventricle) contracts, pushing blood out into the aorta, the main artery that carries blood to the body. The aortic valve is located between the left ventricle and the aorta and prevents blood from leaking back into the ventricle.
Aortic regurgitation, also known as aortic valve regurgitation or aortic valve insufficiency, occurs when the aortic valve doesn't completely close and allows some blood to leak back into the heart. Aortic regurgitation is classified as trivial, mild, moderate or severe.
Aortic regurgitation symptoms
Aortic valve regurgitation usually doesn't cause symptoms in infants or children. As a child grows, however, abnormal signs and symptoms may appear, including fatigue or a heart murmur (an extra heart sound heard when a doctor listens to the child’s heart with a stethoscope). In rare cases, a leaky aortic valve may cause chest pain, fainting or arrhythmias.
Testing and diagnosis for aortic regurgitation
If your child’s pediatrician detects a heart murmur, you may be referred to the the Cardiac Center at Children’s Hospital of Philadelphia (CHOP). Diagnosing aortic regurgitation may require some or all of these tests:
- Pulse oximetry: a noninvasive way to monitor the oxygen content of the blood
- Chest X-ray
- Echocardiogram (also called "echo" or cardiac ultrasound): ultrasound waves create an image of the heart and can show the size, shape and movement of the heart's valves and chambers as well as the flow of blood through the heart
- Electrocardiogram (ECG): a record of the electrical activity of the heart
- Exercise stress test
- Cardiac MRI: a three-dimensional image that shows the heart's abnormalities
- Cardiac catheterization: a thin tube is inserted into the heart through a vein and/or artery in the leg which takes measurements throughout the heart
Treatments for aortic regurgitation
In cases of trivial or mild aortic regurgitation, treatment may not be necessary. Your child’s cardiologist will monitor your child and may prescribe medication if the regurgitation is moderate or severe. For more severe cases of aortic regurgitation, one of the following treatment options may be needed.
Just like each child is different, so is each heart. Valve repair and replacement is highly individualized, depending on your child’s age and unique anatomy. Your care team will use the most advanced imaging technology to carefully review your child’s heart and make the best possible treatment plan to meet their needs. Learn more about some of the valve repair and replacement procedures that are commonly performed in the Cardiac Center at CHOP.
Valvuloplasty
In severe cases of aortic regurgitation, a surgeon may need to repair or replace the leaky aortic valve. Depending on your child’s age and unique anatomy, your surgeon may repair the valve or improve its function with a procedure called a valvuloplasty.
Artificial valve surgery
Another option to treat aortic regurgitation includes the use of a mechanical (artificial) valve as a replacement valve. If your child receives a mechanical valve, they may need to stay on blood-thinning medicines for the rest of their life to lower the risk of developing blood clots.
Ross Procedure
A third option is the Ross Procedure, an operation in which the aortic valve is replaced with the patient's own pulmonary valve. During the procedure, the pulmonary valve is replaced with a pulmonary valve from a donated organ. This procedure allows the patient's own pulmonary valve (now in the aortic position) to grow with the child. Blood thinners are not required.
Outlook for aortic regurgitation
Due to the enormous strides in medicine and technology in recent years, most children with heart conditions today go on to lead healthy, productive lives as adults.
Follow-up care
Through 18 years
Children with aortic regurgitation require regular checkups with a pediatric cardiologist. Some children must remain on medication and limit physical activity. At CHOP, our pediatric cardiologists follow patients until they are young adults and coordinate care with primary care physicians.
Into adulthood
Aortic regurgitation can cause health problems in adults. It is very important that adults with this condition are monitored by a cardiologist regularly for the rest of their lives. CHOP’s Cardiac Center can help with the transition to an adult cardiologist.
The Philadelphia Adult Congenital Heart Center, a joint program of CHOP and Penn Medicine, meets the unique needs of adults who were born with heart defects.
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