Primary Sclerosing Cholangitis

What is primary sclerosing cholangitis?

Bile ducts serve as passageways to drain bile from the liver. In primary sclerosing cholangitis (PSC) inflammation causes the bile ducts to become too narrow and eventually they are blocked completely.

The cause of the inflammation is unknown and there is currently no cure for PSC.

At The Children's Hospital of Philadelphia, children with PSC are managed by hepatologists and gastroenterologists in the Biesecker Pediatric Liver Center and the Division of Gastroenterology (GI), Hepatology and Nutrition.