Education and Training

Medical School

MD - University of Kansas Medical Center, Kansas City, KS


Pediatrician Scientist Development and Training Program - Texas Children’s Hospital, Baylor College of Medicine, Houston, TX


Pediatric Gastroenterology and Hepatology - Children's Hospital of Philadelphia, Philadelphia, PA

Board Certification

Pediatrics – American Board of Pediatrics

Graduate Degree

PhD in Anatomy and Cell Biology - University of Kansas Medical Center, Kansas City, KS and Stowers Institute for Medical Research, Kansas City, MO

Titles and Academic Titles

Pediatric Gastroenterologist

Instructor, Perelman School of Medicine at the University of Pennsylvania

Departments and Services




Lee, C., Chatty, P, Tjaden, N. A woman with pancreatic-insufficient cystic fibrosis and abdominal pain. Gut (submitted March 7, 2022).


Butler Tjaden, N.E., Chiou, E., Pillai, N., Schady, D.A., Chumpitazi, B. Gastrointestinal dysmotility is a significant feature in two siblings with a novel ITPR1 missense variant identified by whole exome sequencing. ACG Case Rep J 2021; Oct 26;8(10):e00676. doi: 10.14309/crj.0000000000000676. PMID: 34722792; PMCID: PMC8549690.


Butler Tjaden, N.E., Barton, K.M., Van Buren, L.K., Fishman, D.S.  Multiple congenital esophageal stenoses in a 15-month-old child.  Journal of Pediatric Gastroenterology and Nutrition. September 2020 - Volume 71 - Issue 3 - p e97 doi: 10.1097/MPG.0000000000002766.


Lenti, E., Farinello, D., Yokoyama, K.K., Penkov, D., Castagnaro, L., Lavorgna, G., Wuputra, K., Sandell, L.L., Butler Tjaden, N.E., Bernassola, F., Caridi, N., De Antoni, A., Wagner, M., Kozinc, K., Niederreither, K., Blasi, F., Pasini, D., Majdic, G., Tonon, G., Trainor, P.A., Brendolan, A. 2016. Transcription factor TLX1 controls retinoic acid signaling to ensure spleen development. Journal of Clinical Investigation 126 (7), 2452-64.


Aoto, K., Sandell, L.L., Butler Tjaden, N.E., Yuen, K.C., Watt, K., Black, B.L., Durnin, M., Trainor, P.A., 2015. Mef2c-F10N enhancer driven beta-galactosidase (LacZ) and Cre recombinase mice facilitate analyses of gene function and lineage fate in neural crest cells. Developmental Biology 402, 3-16.


Sandell, L.L., Butler Tjaden, N.E., Barlow, A., Trainor, P.A., 2014. Cochleovestibular nerve development is integrated with migratory neural crest cells. Developmental Biology 385, 200-210.


Billings, S.E., Pierzchalski, K., Butler Tjaden, N.E., Pang, X.-Y., Trainor, P.A., Kane, M.A., Moise, A.R., 2013. The retinaldehyde reductase DHRS3 is essential for preventing the formation of excess retinoic acid during embryonic development. FASEB J 27, 4877-4889.

Butler Tjaden, N.E., Trainor, P.A., 2013. The developmental etiology and pathogenesis of Hirschsprung disease. Transl Res 162, 1-15.




Butler Tjaden, N.E., Tjaden Jr, B.L.: Chapter 58: Hernias. Netter's Pediatrics, 2nd Edition. Rebecca Tenney Soeiro, MD, MSEd and Erin Pete Devon, MD (eds.). Elsevier, Page: 344-48, 2022.

Posters and Presentations

Invited Lectures


Pediatric Constipation, Family Medicine Grand Rounds, Hospital at the University of Pennsylvania, PA. Apr 2023.

Awards and Honors

2023, American Neurogastroenterology and Motility Young Investigator Recipient
2022-2023, CHOP Laboratory-Based Research Poster Award
2020, Pediatric Research Symposium Cover Art Competition
2017, 1st place Southwest Society of Developmental Biology BioArt Competition
2016, Institutional Winner, Capitol Graduate Research Summit
2016, Paul B. Freeburg Award in Cell Biology
2015, University of Kansas Medical Center (KUMC) Graduate Studies Award
2015, 1st place KUMC Student Research Forum Oral Presentation
2015-2016, Featured Image in “Cravings” Exhibit at the London Science Museum
2014,“Best of Little Brain Big Brain” Oral Presentation (Guangzhou, China)
2014, 1st place KUMC Student Research Forum Poster Session Award
2007, Undergraduate Research Opportunities Program (UROP) Poster Award

Editorial and Academic Positions

Editorial Positions

2021-present, Ad hoc reviewer, Journal of Pediatric Gastroenterology and Nutrition (JPGN)

Leadership and Memberships

Memberships in Professional Organizations


2014-present, Little Brain Big Brain


2022-present, North American Society For Pediatric Gastroenterology, Hepatology & Nutrition
 - 2022-present, Research Committee
2021-present, American Gastroenterological Association (AGA)
2020-present, American Neurogastroenterology and Motility Society (ANMS)
2018-present, Society for Developmental Biology (SDB)
2017-present, American Academy of Pediatrics (AAP)