Alan R. Cohen, MD

Medical School

MD - University of Pennsylvania School of Medicine, Philadelphia, PA

Internship

The Children's Hospital of Philadelphia, Philadelphia, PA

Residency

The Children's Hospital of Philadelphia, Philadelphia, PA (Chief Resident)

Fellowship

Hematology-Oncology - The Children's Hospital of Philadelphia, Philadelphia, PA

Board Certification

Hematology/Oncology
Pediatrics

Papers

2018

Vichinsky E, Cohen A, Thompson AA, Giardina PJ, Lal A, Paley C, Cheng WY, McCormick N, Sasane M, Qiu Y, Kwiatkowski JL: Epidemiologic and clinical characteristics of thalassemia intermedia in the United States. Pediatr Blood Cancer. 2018 Jul;65(7):e27067. doi: 10.1002/pbc.27067. Epub 2018 Apr 10.

Zielonka B, Cohen A, Skith-Whitley K, Doshi BS. Iliopsoas Hematoma in a Patient with Sickle Cell Disease. Pediatr Blood Cancer. 2018 Jul;65(7):e27040. doi: 10.1002/pbc.27040. Epub 2018 Mar 12.

2017

Taher AT, Saliba AN, Kuo KH, Giardina PJ, Cohen AR, Neufeld EJ, Aydinok Y, Kwiatkowski JL, Chapin JC, Kramer W, Jeglinski BI, Pietropaulo K, Berk G Viprakasit V. Safety and pharmacokinetics of the oral iron chelator SP-420 in β-thalassemia. Am J Hematol 92:1356-1361, 2017.

2016

Wood JC, Cohen AR, Pressel SL, Aygun B, Imran H, Luchtman-Jones L, Thompson AA, Fuh B, Schultz WH, Davis BR, and Ware RE. Organ iron accumulation in chronically transfused children with sickle cell anemia: baseline results from the TWiTCH trial. Br J Haematol 172:122-130, 2016.

2015

Ware RE, Davis BR, Schultz WH, Brown, RC, Aygun B, Sarnaik SA, Odame I, Fuh B, George A, Owen W, Luchtman-Jones L, Rogers ZR, Hilliard L, Gauger C, Piccone CM, Lee MT, Kwiatkowski JL, Jackson S, Miller ST, Roberts CW, Heeney MM, Kalfa TA, Nelson SC, Imran H, Nottage KA, Alvarez OA, Rhodes M, Thompson AA, Rothman J, Helton KJ, Roberts D, Coleman J, Bonner MJ, Kutlar A, Patel N, Wood JC, Piller L, Wei P, Luden J, Mortier NA, Stuber S, Luban NLC, Cohen AR, Pressel SL, and Adams RJ. TCD with transfusions changing to hydroxyurea (TWiTCH): hydroxyurea therapy as an alternative to transfusions for primary stroke prevention in children with sickle cell anemia. Lancet 387:661-670, 2015.

Wood JC, Pressel S, Rogers ZR, Odame I, Kwiatkowski JL, Lee MT, Owen WC, Cohen AR, St Pierre T, Heeney MM, Schultz WH, Davis BR and Ware RE. Liver iron concentration measurements by MRI in chronically transfused children with sickle cell anemia: baseline results from the TWiTCH trial. Am J Hematol 90: 806-810, 2015.

Aygun B, Mortier NA, Kesler K, Lockhart A, Schultz WH, Cohen AR, Alvarez O, Rogers ZR, Kwiatkowski JL, Miller ST, Sylvestre P, Iyer R, Lane PA, Ware RE; Stroke With Transfusions Changing to Hydroxyurea (SWiTCH) Trial Investigators. Therapeutic phlebotomy is safe in children with sickle cell anaemia and can be effective treatment for transfusional iron overload.  Br J Haematol 169:262-266, 2015.

2014

Vichinsky E, Neumayr L, Trimble S, Giardina PJ, Cohen AR, Coates T, Boudreaux J, Neufeld EJ, Kenney K, Grant A, Thompson AA, CDC Thalassemia Investigators. Transfusion complications in thalassemia patients: a report from the Centers for Disease Control and Prevention. Transfusion 54:972-981, 2014.

2013

Pennell DJ, Udelson JE, Arai AE, Bozkurt B, Cohen AR, Galanello R, Hoffman TM, Kiernan MS, Lerakis S, Piga A, Porter JB, Walker JM, Wood J; American Heart Association Committee on Heart Failure and Transplantation of the Council on Clinical Cardiology and Council on Cardiovascular Radiology and Imaging.  Cardiovascular Function and Treatment in Beta-Thalassemia Major: A Consensus Statement. Circulation 128:281-308, 2013.

Block RW, Dreyer, BP, Cohen AR, Stapleton FB, Furth SL, Bucciarelli RL.  An agenda for children for the 113 Congress: Recommendations from the Pediatric Academic Societies.  Pediatrics 131:109-119, 2013.

2012

Marx A, Shaw K, Taylor A, Cohen A.  Department of Pediatrics Chair’s Initiatives: Promoting innovation and improvement through collaboration, accountability, and faculty development.  J Pediatr 161:377-378, 2012.

Kwiatkowski JL, Kim HY, Thompson AA, Quinn CT, Mueller BU, Odame I, Giardina PJ, Vichinsky EP, Boudreaux JM, Cohen AR, Porter JB, Coates T, Olivieri NF, Neufeld EJ; Thalassemia Clinical Research Network.  Chelation use and iron burden in North America and British thalassemia patients: a report from the Thalassemia Longitudinal Cohort. Blood 119:2746-2753, 2012.

Kwiatkowski JL, Cohen AR, Garro J, Alvarez O, Nagasubramanian R, Sarnaik S, Thompson A, Woods GM, Scultz W, Mortier N, Lane P, Mueller B, Yovetich N, Ware RE; for the SWiTCH Study Investigators. Transfusional iron overload in children with sickle cell anemia on chronic transfusion therapy for secondary stroke prevention. Am J Hematol  87:221-223, 2012.

2011

Neunert C, Lim W, Crowther M, Cohen A, Solberg, Jr., L, Crowther MA.  The American Society of Hematology 2011 evidence-based practice guidelines for immune thrombocytopenia. Blood 117:4190-4207, 2011.

Cappellini MD, Bejaoui M, Agaoglu L, Canatan D, Capra M, Cohen A, Drelichman G, Economou M, Fattoum S, Kattamis A, Kilinc Y, Perrotta S, Pga A, Porter JB, Griffel L, Dong V, Clark J, Aydinok Y.  Iron chelation with deferasirox in adult and pediatric patients with thalassemia major: efficacy and safety during 5 years’ follow-up. Blood 118:884-893, 2011.

2010

Kirk P, Anderson LJ, Roughton M, Tanner MA, Lam WW, Au WY, Chu WC, Chan G, Galanello R, Matta G, Fogel M, Cohen AR, Tan RS, Chen K, Ng I, Lai A, Fucharoen S, Laothamata J, Chuncharunee S, Jongjirasiri S, Firmin DC, Smith GC, Pennell DJ. International reproducibility of single breathhold T2* MR for cardiac and liver iron assessment among five thalassemia centers. J Magn Reson Imaging 32:315-319, 2010.

2008

He T, Kirk P, Firmin DN, Lam WM, Chu WC, Au WY, Chan GC, Tan RS, Ng I, Biceroglu S, Aydinok Y, Fogel MA, Cohen AR, Pennell DJ. Multi-center transferability of a breath-hold T2 technique for myocardial iron assessment. J Cardiovasc Magn Reson. 10:11, 2008.

Cohen AR, Glimm E, Porter JB.  Effect of transfusional iron intake on response to chelation therapy in ß-thalassemia major. Blood 111:583-587, 2008.

2007

Song R, Cohen AR, Song HK.  Improved transverse relaxation rate measurement techniques for the assessment of hepatic and myocardial iron content.  J Magn Reson Imaging 26: 208-214, 2007.

Manco-Johnson, MJ, Abshire TC, Shapiro AD, Riske B, Hacker MR, Kilcoyne R,       Ingram JD, Manco-Johnson ML, Funk S, Jacobson L, Valentino LA, Hoots WK, Buchanan GR, DiMichele D, Recht M, Brown D, Leissinger C, Bleak S,      Cohen A, Mathew P, Matsunaga A, Medeiros D, Nugent D, Thomas GA, Thompson AA, McRedmond K, Soucie JM, Austin H, Evatt BL.  Prophylaxis versus episodic treatment to prevent joint disease in boys with severe hemophilia.  NEJM 357:535-544, 2007.

2006

Cappellini MD, Cohen A, Piga A, Bejaoui M, Perrotta S, Agaoglu L, Aydinok Y, Kattarnis A, Yurdanur K, Porter J, Capra M, Galanello R, Fattoum S, Drelichman G, Magnano C, Verissimo M, Athanassiou-Metaxa M, Giardina P, Kourakli-Symeonidis A, Janka-Schaub G, Coates T, Vermylen C, Olivieri N, Thuret I, Opitz H, Ressayre-Djaffer C, Marks P, Alberti D.  A Phase 3 study of deferasirox (ICL670), a once-daily oral iron chelator, in patients with β-thalassemia. Blood 107:3455-3462, 2006.

Vogiatzi MG, Macklin EA, Fung EB, Vichinsky E, Olivieri N, Kwiatkowski J, Cohen A, Neufeld E, Giardina PJ.  Prevalence of fractures among the thalassemia syndromes in North America.  Bone 38:571-575, 2006.

Borgna-Pignatti C, Ventola M. Friedman D, Cohen AR, Origa R, Galanello, R, Lindeman R, Francis S, Reverberi R, Volpato S.  Seasonal variation of pre-transfusion hemoglobin levels in patients with thalassemia major.  Blood 107:355-357, 2006.

2005

Armanios M, Chen JL, Chang, YC, Brodsky RA, Hawkins A, Griffin CA, Eshleman JR, Cohen AR, Chakravarti A, Hamosh A, Greider CW.  Haploinsufficiency of telomerase reverse transcriptase leads to anticipation in autosomal dominant dyskeratosis congenita.  Proc Natl Acad Sci USA 102:15960-15964, 2005.

Wang ZJ, Lian L, Chen Q, Zhao H, Asakura T, Cohen AR.  1/T2 and magnetic susceptibility measurements in a gerbil cardiac iron overload model.  Radiology 234:749-755, 2005.

2004

Chu Z, Cohen AR, Muthupillai R, Chung T, Wang ZJ.  MRI measurement of hepatic magnetic susceptibility — phantom validation.  Magnetic Resonance in Medicine 52:1318-1327, 2004.

Chou ST, Shah SS, Hodinka RL, Cohen AR. Positive heterophile antibody test and massive splenomegaly in an adolescent with previously unsuspected Gaucher disease.  Pediatr Emerg Care 20:181-184, 2004.

Cunningham MJ, Macklin EA, Neufeld EJ, Cohen AR, Thalassemia Clinical Research Network. Complications of beta-thalassemia major in North America.   Blood 104:34-39, 2004.

2003

Cohen AR, Galanello R, Piga A, DeSanctis V, Tricta F. Safety and effectiveness of long-term therapy with the oral iron chelator deferiprone. Blood 102:1583-1587, 2003.

Patterson M, Walker L, Chui DHK, Cohen AR, Waye JS.  Identification of a new β-thalassemia nonsense mutation [Codon 59 (AAG→ TAG)].  Hemoglobin 27:201-203, 2003.

Hoffbrand AV, Cohen A, Hershko C. Role of deferiprone in chelation therapy for transfusional iron overload: Blood 102:17-24, 2003.

2002

Wanless IR, Sweeney G, Dhillon AP, Guido M, Piga A, Galanello R, Gamberini MR, Schwartz E, Cohen AR.  Lack of progressive hepatic fibrosis during long-term  therapy with deferiprone in subjects with transfusion-dependent beta-thalassemia.  Blood 100:1566-1569, 2002.

Goedert JJ, Eyster ME, Lederman MM, Mandalaki T, de Moerloose P, White GC, Angiolillo A, Luban NLC, Sherman KE, Manco-Johnson M, Preiss L, Leissinger C, Kessler CM, Cohen AR, DiMichele D, Hilgartner MW, Aledort LM, Kroner BL, Rosenberg PS, Hatzakis A.  End-stage liver disease in persons with hemophilia and transfusion-associated infections.  Blood 100:1584-1589, 2002. 

Wang ZJ, Haselgrove JC, Martin MB, Hubbard AM, Li S, Loomes K, Moore JR, Zhao H, Cohen AR. Evaluation of iron overload by single voxel MRS measurement of liver T2. JMRI 15:395-400, 2002.

2001

Kulkarni R, Aledort LM, Berntorp E, Brackman HH, Brown D, Cohen AR, Ewing NP, Gringeri A, Gruppo R, Hoots K, Leissenger C, Peerlinck K, Poon M, Wong W. Therapeutic choices for patients with hemophilia and high-titer inhibitors. Am J Hematol 67:240-246, 2001.

Vesley S, Buchanan GR, Adix L, George JN, Cohen AR, Blanchette VS, Kuhne T.  Self- reported initial management of childhood idiopathic thrombocytopenic purpura: Results of a survey of members of the American Society of Pediatric Hematology/Oncology.  J Pediatr Hematol/Oncol 25:130-133, 2001.

2000

Vesely S, Buchanan GR, Cohen A, Raskob G, George J. Self-reported diagnostic and  management strategies in childhood idiopathic thrombocytopenic purpura:   Results of a survey of practicing pediatric hematology-oncology specialists.    J Pediatr Hematol/Oncol 22:55-61, 2000.

Cohen AR, Galanello R, Piga A, DiPalma A, Vullo C, Tricta F.  Safety profile of the oral  iron chelator deferiprone:  A multi-center study.  Br J Haematol 108:305-312, 2000.

1999

Kwiatkowski JL, West TB, Heidary N, Smith-Whitley K, Cohen AR.  Severe iron deficiency anemia in young children.  J Pediatr 135:514-516, 1999.

1999

Nguyen GT, Carrington M, Beeler JA, Dean M, Aledort LM, Blatt PM, Cohen AR, O’Brien TR. Phenotypic expressions of CCR5-32/32 homozygosity. J Acquir Immune Defic Syndr 22:75-82, 1999.

1998

Cohen A, Galanello R, Piga A, Vullo C, Tricta F.  A multi-center safety trial of the oral iron chelator deferiprone, Ann NY Acad Sci 850:223-226, 1998.

1997

Larson P, Friedman D, Reilly M, Kattamis A, Asakura T, Fortina P, Cohen A, Kim H, Manno C.  The presurgical management of a patient with a high oxygen affinity, unstable hemoglobin variant (Hb Bryn Mawr) with erythrocytapheresis.  Transfusion 37:703-707, 1997.

Nuss R, Stultz J, Ramafedi G, Lloyd Schultz S, Cohen A.  Health care provider and self-assessment of health status and sexual behaviour in HIV-seropositive young men with haemophilia.  Haemophilia 3:270-276, 1997.

Camaschella C. Kattamis A, Petroni D, Roetto A, Sivera P, Sbaiz L, Cohen A, et al.  Different hematological phenotypes caused by the interaction of triplicated globin genes and heterozygous -thalassemia.  Am J Hematol 55:83-88, 1997.

Levine JE, Cohen AR, McQueen M, Martin M, Giardina PJ.  Sensorimotor neurotoxicity associated with high-dose deferoxamine treatment.  Am J Pediatr Hematol/Oncol 19:139-141, 1997.

Kelly KM, Butler, RB, Farace L, Cohen AR, Manno CS.  Superior in vivo response of recombinant factor VIII concentrate in children with hemophilia A.  J Pediatr 130:537-540, 1997.

Kattamis AC, Shankar S, Cohen AR.  Neurologic complications of treatment of childhood acute immune thrombocytopenic purpura with intravenous immunoglobulin G.  J Pediatr 130:281-283, 1997.

Borgna-Pignatti C, Cohen A.  Evaluation of a new method of administration of the iron chelating agent deferoxamine.   J Pediatr 130:86-88, 1997.

1996

Borgna-Pignatti C, Cohen A.  Evaluation of a new method of administration of the iron chelating agent deferoxamine.   J Pediatr 130:86-88, 1997.

Ludlow LB, Schick BP, Budarf ML, Driscoll DA, Zackai EH, Cohen A, Konkle BA.  Identification of a mutation in a GATA binding site of the platelet glycoprotein Ib promoter resulting in the Bernard-Soulier Syndrome.  J Biol Chem 271:22076-22080, 1996.

O’Brien TR, Blattner WA, Waters D, Eyster E, Hilgartner MW, Cohen AR, Luban N, Hatzakis A, Aledort LM, Rosenberg PS, Miley WJ, Kroner BL, Goedert JJ.  Serum HIV-1 RNA levels and time to development of AIDS in the multicenter hemophilia cohort study.  JAMA 276:105-110, 1996.

Pearson HA, Cohen A, Giardina PV, Kazazian HH.  The changing profile of homozygous beta thalassemia.  Pediatrics 97:352-356, 1996.

1995

Cohen AR, Martin MB, Schwartz E.  Hydroxyurea therapy in thalassemia intermedia.  Colloque Inserm 234:193-194, 1995.

Lederman MM, Jackson JB, Kroner BL, White GC, Eyster ME, Aledort LM, Hilgartner MW, Kessler CM, Cohen AR, Kiger KP, Goedert JJ. Human immunodeficiency virus (HIV) Type I infection status and in vitro susceptibility to HIV infection among high-risk HIV-1-seronegative hemophiliacs.  J Infect Dis 172:228-231, 1995.

Maris JM, Butler RB, Cohen AR.  Loss of detectable antibody to the hepatitis B surface antigen in previously immunized HIV negative hemophiliacs.  J Pediatr 126:269-271, 1995.

1994

Goedert JJ, Cohen AR, Kessler CM, Eichinger S, Seremetis SV, Rabkin CS, Yellin FJ, Rosenberg PS, Aledort LM.  Risks of immune deficiency, AIDS and death by purity of factor VIII concentrate. Lancet 344:791-792, 1994.

Kim HC, Dugan NP, Silber JH, Martin MB, Schwartz E, Ohene-Frempong K, Cohen AR. Erythrocytapheresis therapy for reduction of iron overload in chronically transfused patients with sickle cell disease. Blood 83:1136-1142, 1994.

Olivieri NF, Nathan DG, MacMillan JH, Wayne A, Liu PP, McGee A, Martin M, Koren G, Cohen AR.  Survival in medically treated patients with homozygous beta-thalassemia.  N Engl J Med 331:574-578, 1994.

1993

Eyster ME, Rabkin CS, Cohen AR, Goedert JJ.  Human immunodeficiency virus-related conditions in children and adults with hemophilia: rates, relationship to CD4 counts, and predictive value.  Blood 81:828-834, 1993.

Brittenham GM, Cohen AR, McLaren, CE, Martin MB, Griffith PM, Nienhuis AW, Young NS, Allen CJ, Farrell DE, Harris JW.  Hepatic iron stores and plasma ferritin concentration in patients with sickle cell anemia and thalassemia major.  Am J Hematol 42:81-85, 1993.

1992

Manno CS, Butler RB, Cohen AR.  Low recovery in vivo of highly purified factor VIII.  J Pediatr 121:814-818, 1992.

Rackoff WR, Ohene-Frempong K, Month S, Scott JP, Neahring B, Cohen AR.  Neurologic events after partial exchange transfusion for priapism in sickle cell disease.  J Pediatr 120:882-885, 1992.

Cohen AR, Martin MB, Silber JH, Kim HC, Ohene-Frempong K, Schwartz E.  A modified transfusion program for prevention of stroke in sickle cell disease.  Blood 79:1657-1661, 1992.

Burk CD, Miller L, Handler SD, Cohen AR.  Pre-operative history and coagulation screening in children undergoing tonsillectomy.  Pediatrics 89:691-695, 1992.

Rabkin CS, Hilgartner MW, Cohen AR, Goedert JJ.  Incidence of lymphomas and other cancers in HIV-infected and HIV-uninfected patients with hemophilia.  JAMA 267:1090-94, 1992.

Young TL, Schaffer DB, Cohen AR.  Infantile glaucoma associated with the Diamond-Blackfan syndrome.  J Pediatr Ophthal Strab 29:55-58, 1992.

1991

Cohen A, Martin M, Ohene-Frempong, K.  Increased blood requirements during long-term transfusion therapy in sickle cell disease.  J Pediatr 118:405-407, 1991.

1990

Cohen A, Martin M, Mizanin J, Konkle DF, Schwartz E.  Vision and hearing during deferoxamine therapy.  J Pediatr 117:326-30, 1990.

Spear ML, Spear M, Cohen AR, Pereira GR.  Effect of fat infusions on platelet concentration in premature infants.  J Parenter Enteral Nutr 14(2):165-168, 1990.

1989

Goedert JJ, Kessler CM, Aledort LM, Biggar RJ, Andes WA, White GC, Drummond JE, Vaidya K, Mann DL, Eyster ME, Ragni MV, Lederman MM, Cohen AR, Bray GL, Rosenberg PS, Friedman RM, Hilgartner MW, Blattner WA, Kroner B, Gail MH.  Rates, markers and cofactors of human immunodeficiency virus type I infection and AIDS in subjects with hemophilia.  N Engl J Med 321:1141-1148, 1989.

Cohen AR, Mizanin J, Schwartz E.  Rapid removal of excessive iron with daily, high-dose intravenous chelation therapy.  J Pediatr 115:151-155, 1989.

Manno CS, Cohen AR.  Splenectomy in spherocytosis:  Is it worth the risk?  Am J Pediatr Hematol/Oncol 11:300-303, 1989.

Cohen A, Gayer R, Mizanin J.  Long-term effect of splenectomy on transfusion requirements in thalassemia major.  Am J Hematol 30:254-256, 1989.

1988

Michelson A, Cohen, A.  Incidence and treatment of fractures in thalassemia.  J Ortho Trauma 2:29-32, 1988.

Schwartz E, Cohen A, Surrey S.  Overview of the beta thalassemias:  Clinical and genetic aspects.  Hemoglobin 12:551-564, 1988.

Cohen A, Seidl-Friedman J.  HemoCue system for hemoglobin measurement: evaluation in anemic and non-anemic children.  Am J Clin Pathol 90:302-305, 1988.

1986

Hoyt R, Scarpa N, Wilmott RW, Cohen A, Schwartz E.  Pulmonary function abnormalities in homozygous beta thalassemia.  J Pediatr 109:452-455, 1986.

1985

Poncz M, Greenberg J, Gill FM, Cohen A. Hematologic changes during acute chest syndrome in sickle cell disease.  Am J Pediatr Hematol Oncol 7:96-99, 1985.

Nelson L, Elfman J, Cohen A.  Management of Ludwig’s angina in a patient with severe hemophilia A with factor VIII inhibitors:  Report of a case.  J Dent Child 52.306-311, 1985.

Cohen A, Mizanin J, Schwartz E.  Treatment of iron overload in Cooley’s anemia.  Ann NY Acad Sci 445:274-281, 1985.

1984

Cohen A, Schmidt JM, Martin M, Barnsley W, Schwartz E.  Clinical trial of young red cell transfusions.  J Pediatr 104:865-868, 1984.

Cohen A, Martin M, Schwartz E.  Depletion of excessive liver iron stores with desferrioxamine.  Br J Haematol 58:369-373, 1984.

1982

Graziano JH, Piomelli S, Seaman C, Wang T, Cohen A, Kelleher JF, Schwartz E. A simple technique for preparation of young red cells for transfusion from ordinary blood units.  Blood 59:865-868, 1982.

1981

Cohen A.  Chelation therapy in the treatment of iron overload.  Drug Ther 6:47-58, 1981.

Cohen A, Martin M, Schwartz E.  Response to long-term deferoxamine therapy in thalassemia.  J Pediatr 99:689-694, 1981.

Cohen A, Cohen I, Schwartz E.  Scurvy and altered iron stores in thalassemia major.  N Engl J Med 304:158-160, 1981.

Cohen A, Trotzky M, Pincus D.  Reassessment of the microcytic anemia of lead poisoning.  Pediatrics 67:904-906, 1981.

Poncz M, Colman N, Herbert V, Schwartz E, Cohen A.  Therapeutic management of congenital folate malabsorption.  J Pediatr 98:76-79, 1981.

1980

Greenberg J, Curtis-Cohen M, Gill FM, Cohen A.  Prolonged reticulocytopenia in autoimmune hemolytic anemia of childhood.  J Pediatr 97:784-786, 1980.

Cohen A, Schwartz E.  Decreasing iron stores during intensive chelation therapy.  Ann NY Acad Sci 344:405-408, 1980.

Cohen A.  Effect of time on hematologic values in prediluted capillary and venous blood.  Am J Clin Pathol 74:306-307, 1980.

Cohen A, Markenson AJ, Schwartz E.  Transfusion requirements and splenectomy in Cooley's anemia.  J Pediatr 97:100-102, 1980.

1979

Cohen A, Schwartz E.  Iron chelation therapy in sickle cell anemia.  Am J Hematol 7:69-76, 1979.

1978

Cohen A, Schwartz E.  Excretion of iron in response to deferoxamine in sickle cell anemia.  J Pediatr 92:659-662, 1978.

Cohen A, Schwartz E.  Iron chelation therapy with deferoxamine in Cooley's anemia.  J Pediatr 92:643-647, 1978.

Abstracts

2016

Wood JC,  St Pierre T, Aygun B, Mortier N, Schultz WH, Piccone CM,, Hankins J, Rogers ZR, Owen W, Odame I, Sarnaik SA, Hilliard L, Cohen AR and Ware RE. Agreement between R2 and R2* liver iron estimates is independent of the type of iron removal therapy: results from the TWiTCH trial. American Society of Hematology Annual Meeting, San Diego, CA, 2016.

Aygun B, Mortier N, Rogers ZR, Owen W, Fuh B, George, A, Kalfa TA, Kwiatkowski J, Lee M, Imran H, Miller ST, Wood JC, Cohen AR, Pressel SL and Ware RE.. Iron unloading by therapeutic phlebotomy in previously transfused children with sickle cell anemia: the TWiTCH Experience. American Society of Hematology Annual Meeting, San Diego, CA, 2016.

2015

Ware WR, Davis BR, Schultz WH, Brown C, Aygun B, Sarnaik SA, Odame I, Fuh B, George A, Owen W, Luchtman-Jones L, Rogers ZR, Hilliard L, Gauger C, Piccone CM, Lee MT, Kwiatkowski J, Jackson S, Miller ST, Roberts CW, Heeney MM, Kalfa TA, Nelson SC, Imran H, Nottage KA, Alvarez OA, Rhodes M, Thompson AA, Rothman J, Helton KJ, Roberts D, Coleman J, Bonner MJ, Kutlar A, Patel N, Wood JC, Piller L, Wei P, Luden J, Mortier NA, Stuber S, Luban NLC, Cohen AR, Pressel SL, and Adams RJ. TCD with transfusions changing to hydroxyurea (TWiTCH): hydroxyurea therapy as an alternative to transfusions for primary stroke prevention in children with sickle cell anemia. American Society of Hematology Annual Meeting (plenary session), Orlando, FL 2015.

Books

2014

Cappellini MD, Cohen A, Porter J, Taher A, Viprikasit V: Guidelines for the Management of Transfusion-Dependent Thalassaemia, 3rd Edition, Thalassaemia International Federation, 2014

Heeney M, Cohen A, editors. Iron Disorders. Hematology-Oncology Clinics of North America, Elsevier Publishing, August 28, 2014

1991

Cohen A, Lange B (guest editors).  Hematology/Oncology Section, Current Opinion in Pediatrics, vol. 3, Current Science, Salem, 1991.

1983

Cohen A, (guest editor).  Perinatal Hematology, Seminars in Perinatology, Grune and Stratton, Inc., New York, 1983.

1980

Sherwood W, Cohen A, editors.  Transfusion Therapy: Fetus, Infant and Child.  Masson Publishing USA, Inc., New York, 1980.

Chapters

2004

Forget B, Cohen AR. Thalassemia Syndromes, in Hoffman R, Benz, Jr. EJ, Shattil SJ, Furie B, Cohen HJ, Silberstein LE, McGlave P, eds, Hematology: Basic Principles and Practice, 4/e.  Church Livingstone, Philadelphia, 2004.

2001

Fisher MJ, Cohen A. Normal red blood cell indices and differential diagnosis of anemia,  Fetal and Neonatal Secrets, Polin RA, Spitzer AR, eds, Hanley and Belfus, Inc., Philadelphia, 2001.

Cohen A, Porter JB. Transfusion therapy, in Disorders of Hemoglobin, Forget BG, Higgs DR, Nagel RL, Steinberg MH, eds, Cambridge University Press, New York, 2001.

2000

Cohen, AR.  Transfusional approaches to the management of iron overload, in Iron Chelators:  New Development Strategies, Badman DG, Bergeron RJ, Brittenham GM, eds, The Saratoga Group, Ponte Vedra Beach, 2000.

Cohen A.  Hematologic emergencies, in Textbook of Pediatric Emergency Medicine, 4th edition,  Fleisher G, Ludwig S, eds, Williams and Wilkins, Baltimore, 2000.

Cohen A.  Pallor, in Textbook of Pediatric Emergency Medicine, 4th edition, Fleisher G, Ludwig eds, Williams and Wilkins, Baltimore, 2000.

Cohen A.  Purpura, in Textbook of Pediatric Emergency Medicine, 4th edition, Fleisher G, Ludwig S, eds, Williams and Wilkins, Baltimore, 2000.

1999

Manno CS, Cohen AR.  Neonatal Anemia:  when to transfuse, in Current Pediatric Therapy 16, Burg FD, Wald ER, Ingelfinger JR, Polin RA, eds, W.B. Saunders Company, Philadelphia, 1999.

Cohen, AR.  Choosing the best strategy to prevent childhood iron deficiency.  JAMA 281:2247-2248, 1999.

1998

Cohen AR, Manno CS.  Transfusion practices in infants receiving assisted ventilation, in Clinics in Perinatology, Volume 25, Number 1, Carin Baniewicz, editor, W.B. Saunders Company, Philadelphia, 1998.

1996

Himelstein B, Cohen A. Hematology, in Pediatric Secrets, 2nd edition, Polin RA and Ditmar MR, eds, Hanley and Belfus, Inc., Philadelphia, 1996.

Cohen AR, Manno CS.  Neonatal anemia, in Intensive Care of the Fetus and Neonate, Spitzer A, ed, Mosby-Yearbook Publishing Company, St. Louis, 1996.

Cohen AR, Norris CF, Smith-Whitley K.  Transfusion therapy for sickle cell disease, in New Directions in Pediatric Hematology, Capon SM and Chambers LA, editors, American Association of Blood Banks, Arlington, 1996.

1994

Cohen A.   Iron overload, in The Sickle Hemoglobinopathies: Science and Medicine, Embury SH, Hebbel RP, Narla M, and Steinberg MH, eds, Raven Press, New York, 1994.

1993

Cohen A.  Pallor, in Textbook of Pediatric Emergency Medicine, 3rd edition, Fleisher G, Ludwig eds, Williams and Wilkins, Baltimore, 1993.

Cohen A.  Purpura, in Textbook of Pediatric Emergency Medicine, 3rd edition, Fleisher G, Ludwig S, eds, Williams and Wilkins, Baltimore, 1993.

Cohen A.  Hematologic emergencies, in Textbook of Pediatric Emergency Medicine, 3rd edition,  Fleisher G, Ludwig S, eds, Williams and Wilkins, Baltimore, 1993.

1989

Cohen A.  Hematology, in Pediatric Secrets, Polin RA, Ditmar MF, eds, Hanley & Belfus, Inc., Philadelphia, 1989.

Cohen A, Mizanin J, Schwartz E.  High-dose intravenous chelation therapy with deferoxamine, in Advances And Controversies In Thalassemia Therapy, Buckner CD, Gale RP and Lucarelli G, editors, Alan R. Liss, Inc., New York, 1989.

1987

Cohen A.  Purpura, in Textbook of Pediatric Emergency Care, Fleisher G, and Ludwig S, editors, Williams and Wilkins, Baltimore, 1987.

Cohen A.  Hematologic emergencies, in Textbook of Pediatric Emergency Care, Fleisher G, and Ludwig S, editors, Williams and Wilkins, Baltimore, 1987.

Cohen A.  Transfusion therapy for disorders of hemoglobin, in Pediatric Transfusion Medicine, Luban NLC and Kasprisin DO, editors, CRC Press, Boca Raton, 1987.

Cohen A.  The management of iron overload in the pediatric patient, in Hematology/Oncology Clinics of North America, Oski F, editor, W.B. Saunders Company, Philadelphia, 1987.

Cohen A.  Pallor, in Textbook of Pediatric Emergency Care, Fleisher G, and Ludwig S, editors, Williams and Wilkins, Baltimore, 1987.

1986

Cohen A.  Scurvy, in Conn’s Current Therapy, Rakel RE, editor, W.B. Saunders Company, Philadelphia, 1985, 1986.

1985

Cohen A.  Transfusion therapy for children and adolescents with hemoglobin disorders, in Hemotherapy in Childhood and Adolescence, Luban NLC and Kolins J, editors, American Association of Blood Banks, Arlington, 1985.

1984

Poncz M, Cohen A, Schwartz E.  Thalassemia, in Advances in Pediatrics, Barness L, editor, Yearbook Medical Publishers, Chicago, 1984.

1983

Cohen A, Frasca P, Schwartz E.  Normal liver iron stores after long-term chelation therapy in thalassemia, in Structure and Function of Iron Storage and Transport Proteins, Urushizaki I et al, editors, Elsevier Science Publishers, Amsterdam, 1983.

Cohen A, Martin M, Schwartz E.  Decreased iron loading with young red cell transfusions, in Structure and Function of Iron Storage and Transport Proteins, Urushizaki I et al, editors, Elsevier Science Publishers, Amsterdam, 1983.

Cohen A, Schwartz E.  Thalassemia, in Brenneman’s Practice of Pediatrics, Harper and Row, Inc., Hagerstown, 1989 (revised, 1983).

1980

Cohen A, Schwartz E.  Transfusion in the newborn period, in Transfusion Therapy:  Fetus, Infant and Child, Cohen A, and Sherwood W, editors, Masson Publishing USA, Inc., New York, 1980.

Cohen A, Sherwood W, Busch S.  Transfusion therapy:  hemolytic disease of the newborn, in Transfusion Therapy:  Fetus, Infant and Child, Sherwood W and Cohen A, editors, Masson Publishing USA, Inc., New York, 1980.

1979

Cohen A, Schwartz E.  Iron overload in children with hemoglobinopathies, in Hemoglobinopathies in Children, Schwartz E, editor, Publishing Sciences Group, Inc., Littleton, 1979.

Posters and Presentations

Invited Lectures

2016

Cohen A. “Thalassemia Patients: Are We Transfusing Them Effectively?” Global Iron Summit, Madrid, Spain. March, 2016.