Jacquelyn Crane, MD

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Jacquelyn Crane, MD, is a pediatric hematologist and oncologist with the Cancer Center at Children's Hospital of Philadelphia.

Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

Education and Training

Medical School

MD - Tufts University School of Medicine, Boston, MA


Pediatrics - University of California Los Angeles, Los Angeles, CA


Pediatric Hematology Oncology - University of California Los Angeles, Los Angeles, CA (Chief Fellow)

Board Certification

Pediatric Hematology-Oncology – American Board of Pediatrics
Pediatrics – American Board of Pediatrics

Titles and Academic Titles

Pediatric Hematologist and Oncologist

Assistant Professor, Perelman School of Medicine at the University of Pennsylvania

Departments and Services




Crane JN, Xue W, Qumseya A, Gao Z, Arndt CAS, Donaldson SS, Harrison DJ, Hawkins DS, Linardic CM, Mascarenhas L, Meyer WH, Rodeberg DA, Rudzinski ER, Shulkin BL, Walterhouse DO, Venkatramani R, Weiss AR: Clinical group and modified TNM stage for rhabdomyosarcoma: A review from the Children's Oncology Group.  Pediatr Blood Cancer Page: e29644, Mar 2022 Notes: Epub ahead of print.

Crane JN, Donaldson SS, Spunt SL, Riniker SM: Comment on: Metastatic rhabdomyosarcoma: Evidence of the impact of radiotherapy on survival. A retrospective single-center experience. Pediatr Blood Cancer Page: e30111, Dec 2022 Notes: Epub ahead of print.


CraneJN, Chang VY, Yong W, Salamon N, Lee H for UCLA Clinical Genomics Center, Kianmahd J, Naghmeh D, Martinez-Agosto JA, Davidson TB: A case report of a novel germline GNAS mutation in medulloblastoma. Pediatr Blood Cancer 67(3): e28103, Mar 2020.

Polverari G, Ceci F, Passera R, Crane J, Du L, Li G, Fanti S, Bemthal N, Eilber FC, Allen-Auerbach M, Czemin J, Calais J, Federman N: [18F]FDG PET /CT for evaluating early response to neoadjuvant chemotherapy in pediatric patients with sarcoma: a prospective single-center trial. EJNMMI Research 10(1): 122, Oct 2020 Notes: *Participated in data analysis and manuscript preparation.


Strobel KL, Crane JN, Bradford KM, Naeini Y, May WA, and Vivian Y Chang: Burkitt Like Lymphoma as the First Presentation of Adenomatous Polyposis Coli. Cancer Gen.  239: 33-35, Nov 2019 Notes: *Participated in conducting literature review, interpretation of the data, and authored discussion section of manuscript.


Yu D, Mathews CA, Scharf JM, Neale BM, Davis LK, Gamazon ER, Derks EM, Evans P, Edlund CK, Crane J, et al: Cross-Disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD. Am J Psychiatry 172(1): 82-93, Jan 2015.


Scharf JM, Yu D, Mathews CA, Neale BM, Stewart SE, Fagerness JA, Evans P, Gamazon E, Edlund CK, Service SK, Tikhomirov A, Osiecki L, Illmann C, Pluzhnikov A, Konkashbaev A, Davis LK, Han B, Crane J, et al. : Genome wide association study of Tourette's syndrome. Mol Psychiatry 18(6): 721-728, Jun 2013.

Stewart SE+, Mayerfeld c+ , Arnold PD+, Crane J, O'Dushlaine C, Fagerness JA, Yu D, Scharf JM, Chan E, Kassam F, Moya PR, Wendland JR, Delorme R, Richter MA, Kennedy JL, Veenstra-VanderWeele J, Samuels J, Greenberg BD, McCracken JT, Knowles JA, Fyer AJ, Rauch SL, Riddle MA, Grados MA, Bienvenu OJ, Cullen B, Wang Y, Shugart YY, Piacentini J, Rasmussen S, Nestadt G, Murphy DL, Jenike MA, Cook EH, Pauls DL, Hanna GL, Mathews CA: Meta-Analysis of Association between Obsessive-Compulsive Disorder and the 3' Region of Neuronal Glutamate Transporter SLCIAI. Am J Med Genet B Neuropsychiatr Genet.  162(4): 367-379, Jun 2013 Notes: + co-first authors.

Stewart SE, Yu D, Scharf JM, Neale BM, Fagerness JA, Mathews CA, Arnold PD, Evans PD, Gamazon ER, Davis LK, Osiecki L, McGrath L, Haddad S, Crane J, et al. : Genome- wide association study of obsessive compulsive disorder. Mol Psychiatry 18(7): 788-798, Jul 2013.


Crane J, Fagerness J, Osiecki L, Gunnell B, Stewart SE, Pauls DL, ScharfJM; : Tourette Syndrome International Consortium for Genetics (TSAICG). Family-based genetic association study ofDLGAP3 in Tourette Syndrome. Am J Med Genet B Neuropsychiatr Genet 156(1): 108-114, Jan 2011.

Sampaio AS, Fagerness J, Crane J, Leboyer M, Delorme R, Pauls DL, Stewart SE: Association Between Polymorphisms in GRIK2 Gene and Obsessive-Compulsive Disorder: A Family-Based Study. CNS Neurosci Ther 17(3): 141-157, Jun 2011.


Crane J, Crane FG: Optimal nonverbal communications strategies physicians should engage in to promote positive clinical outcomes. Health Mark Q 27(3): 262-274, Jul 2010.


Quarantini LC, Miranda-Scippa A, Batista-Neves S, Powell VB, Abreu N, Abreu KC, Moura I, Crane J, Sampaio AS, Netto LR, Deoliveira IR, Parana R, Bressan RA, Lacerda AL.: A neuropsychological study comparing patients infected with HCV- and HBV without psychiatric comorbidities. J Med Virol 81(7): 1184-1188, Jul 2009.

Crane JN: Religion and cancer: examining the possible connections. J Psychosoc Oncol 27(4): 469-486, 2009.

Posters and Presentations

Invited Lectures


Trial concept for Relapsed Rhabdomyosarcoma, Soft Tissue Sarcoma Committee Meeting during the Spring Meeting of the Children's Oncology Group, Atlanta, GA. Mar 2023.


Federman N, Kaneva K, Crane J, Chang, V, Singh AS, Bemthal NM, Yanagawa J, Ashok A, Mauer E. The genomic and immune landscape of osteosarcoma. Abstract and poster presentation at the 2022 annual meeting of the Connective Tissue Oncology Society; Vancouver, CA. Nov 2022.

Federman N, Crane J, Gonzales A, Arias R, Baroudi M, Singh A. A phase 1 dose- escalation /expansion clinical trial of mocetinostat in combination with vinorelbine in adolescents and young adults with refractory and/or recurrent rhabdomyosarcoma: Interim results. Abstract and poster presentation at the 2022 annual meeting of the American Society of Clinical Oncology; Chicago, IL. June 2022.


Crane J, Graham D, Mona C, Nelson S, Samiei A, Dawson D, Dry S, Crompton J, Benz M, CzerninJ, Eilber F, GraeberT, Calais J, Federman N. Fibroblast activation protein alpha expression in sarcomas. Abstract and poster presentation at the 2021 annual meeting of the Connective Tissue Oncology Society; virtual conference. Nov 2021.

Clinical Group and TNM Staging Systems for Rhabdomyosarcoma, Remote Presentation, Soft Tissue Sarcoma Committee Meeting during the Fall Meeting of the Children's Oncology Group, virtual. Sept 2021.

Rhabdomyosarcoma: The evolution of the Clinical Group and TNM Staging Systems and proposals for change, Remote Presentation, Soft Tissue Sarcoma Committee Meeting during the Spring Meeting of the Children's Oncology Group, virtual. Mar 2021.


Crane J, Federman N, Graeber T. Working to the bone: osteosarcoma genomics across the temporospatial disease trajectory. Selected oral presentation at the 7th Annual University of California Los Angeles Children's Discovery & Innovation Institute Symposium; Los Angeles, CA. May 2020.

Crane J, Federman N, Graeber T. Transcriptomics of primary and metastatic osteosarcoma. Poster presented at the University of California Los Angeles Children's Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research 16th Annual Stem Cell Symposium; Los Angeles, CA. Feb 2020.

Awards and Honors

2022, Bertil Glader Award for Outstanding Teaching and Mentoring, Stanford University School of Medicine Pediatric Hematology Oncology Fellowship Program
2019, Awardee, Medical Educators Institute, American Society of Hematology
2017, Alice Litman Moss Award, University of California Los Angeles Pediatric Residency Program
2014, Class award for best bedside manner, Tufts University School of Medicine
2012, Honoree of the one hundred award, Massachusetts General Hospital Cancer Center

Editorial and Academic Positions

Editorial Positions

2020-present, Ad Hoc Reviewer, Journal of Pediatric Hematology Oncology

Leadership and Memberships

Memberships in Professional Organizations

2022-present, American Society of Clinical Oncology
2020-present, Connective Tissue Oncology Society (CTOS)
2018-present, Children's Oncology Group (COG)
2018-present, American Society of Pediatric Hematology/Oncology (ASPHO)