Karl Degenhardt, MD, PhD, is an attending cardiologist with the Cardiac Center and Fetal Heart Program at Children's Hospital of Philadelphia.
Despite having many responsibilities, Dr. Degenhardt says that, ultimately, he has two primary jobs. “One is to make an accurate assessment of the patient’s conditions and come up with the best plan for management. The second is to be sure that the patient and family understand what I am thinking and why I am making my recommendations.”
His decision to pursue pediatric cardiology was made at the Mount Sinai School of Medicine, where he completed his MD and PhD. He explains, “I know it sounds nerdy, but for me, the relationship between the anatomy of the heart and its function in the patient’s overall cardiovascular system just had a logical appeal.”
Looking to the future, Dr. Degenhardt talked about the role patient feedback is playing in the evolution of pediatric cardiology. “The population of patients surviving with congenital heart disease is growing exponentially,” he says. “These patients are teaching us what to expect and how to help the next generation.”
Education and Training
MD - Mount Sinai School of Medicine, New York, NY
Pediatrics - Schneider Children’s Hospital, New Hyde Park, NY
Pediatric Cardiology - The Children's Hospital of Philadelphia, Philadelphia, PA
PhD - Mount Sinai School of Medicine, New York, NY
Titles and Academic Titles
Assistant Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania
Departments and Services
Saul D, Degenhardt K, Iyoob SD, Surrey LF, Johnson AM, Johnson MP, Rychik J, Victoria T. Hypoplastic left heart syndrome and the nutmeg lung pattern in utero: a cause and effect relationship or prognostic indicator? Pediatr Radiol. 2016 Apr;46(4):483-9. doi: 10.1007/s00247-015-3514-6. Epub 2015 Dec 21.
Patel MR, Pandya KG, Lau-Cam CA, Singh S, Pino MA, Billack B, et al. Design and synthesis of N-substituted indazole-3-carboxamides as poly(ADP-ribose)polymerase-1 (PARP-1) inhibitors(†). Chem Biol Drug Des. 2012 Apr;79(4):488-96. doi: 10.1111/j.1747-0285.2011.01302.x. Epub 2012 Jan 30. Cited in PubMed; PMID 22177599.
Katz TC, Singh MK, Degenhardt K, Rivera-Feliciano J, Johnson RL, Epstein JA, et al. Distinct compartments of the proepicardial organ give rise to coronary vascular endothelial cells. Dev Cell. 2012 Mar 13;22(3):639-50. Cited in PubMed; PMID 22421048.
Degenhardt K, Wright AC, Horng D, Padmanabhan A, Epstein JA. Rapid 3D phenotyping of cardiovascular development in mouse embryos by micro-CT with iodine staining. Circ Cardiovasc Imaging. 2010 May;3(3):314-22. Epub 2010 Feb 27. Cited in PubMed; PMID 20190279.
Degenhardt KR, Milewski RC, Padmanabhan A, Miller M, Singh MK, Lang D, et al. Distinct enhancers at the Pax3 locus can function redundantly to regulate neural tube and neural crest expressions. Dev Biol. 2010 Mar 15;339(2):519-27. Epub 2010 Jan 4. Cited in PubMed; PMCID: PMC2830354.
Degenhardt K, Singh MK, Massera D, Wang Q, Li J, Lu M, et al. Anomalous pulmonary venous connections result from disruption of sema3D [abstract]. Weinstein Cardiovascular Development Conference; 2011 May 5-7; Cincinnati, OH.
Degenhardt K. Embryology of the cardiovascular system. In: Rychik J, Tian Z, editors. Fetal cardiovascular imaging: a disease based approach. Philadelphia: Elsevier; 2011. p. 10-16.
Patient Experience Ratings
About the Patient Experience Rating System
The Patient Experience Rating is an average of all responses to the care provider related questions shown above from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.
Responses are measured on a scale of 1 to 5 with 5 being the best score.
We are committed to true transparency. However, to ensure the comments are fair and correctly attributed, we review each one before posting to the website. We exclude entire comments that disclose patient's protected health information, are off-topic, or include other confidential or inappropriate content. Comments will appear on provider bios only if providers have a minimum number of comments.
Comments are shared internally for education purposes to ensure that we are doing our very best for the patients and families for whom we are privileged to care.
The comments are submitted by patients and families and reflect their views and opinions. The comments are not endorsed by and do not reflect the views of Children’s Hospital of Philadelphia.