J. Wesley Diddle, MD

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J. Wesley Diddle, MD, is an attending physician with the Department of Anesthesiology and Critical Care Medicine at Children's Hospital of Philadelphia.

Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

Education and Training

Medical School

MD - University of Tennessee Health Sciences Center, Memphis, TN

Internship

Pediatrics - Seattle Children’s Hospital, Seattle, WA

Residency

Pediatrics - Seattle Children’s Hospital, Seattle, WA

Fellowship

Pediatric Critical Care Medicine - Children’s Hospital of Pittsburgh, Pittsburgh, PA
Pediatric Cardiology - Boston Children’s Hospital, Boston, MA

Board Certification

Pediatric Cardiology – American Board of Pediatrics
Pediatric Critical Care Medicine – American Board of Pediatrics
Pediatrics – American Board of Pediatrics

Titles and Academic Titles

Attending Physican, Cardiac Critical Care Medicine

Departments and Services

Publications

Papers

2022

Berg R, et al.  Diastolic Blood Pressure Threshold during Pediatric CPR and Survival Outcomes: a Multicenter Validation Study. Crit Care Med.  2022  In Press

Yurasek G, et al.  Interprofessional ECPR Simulations Aimed at Decreasing Actual Cannulation Times: A Longitudinal Study.  Simulation in Healthcare.  2022  In Press

Morgan RW, Wolfe HA, Reeder RW, Alvey JS, Frazier AH, Friess SH, Maa T, McQuillen PS, Meert KL, Nadkarni VM, Sharron MP, Siems A, Yates AR, Ahmed T, Bell MJ, Bishop R, Bochkoris M, Burns C, Carcillo JA, Carpenter TC, Dean JM, Diddle JW, Federman M, Fernandez R, Fink EL, Franzon D, Hall M, Hehir D, Horvat CM, Huard LL, Manga A, Mourani PM, Naim MY, Notterman D, Pollack MM, Sapru A, Schneiter C, Srivastava N, Tabbutt S, Tilford B, Viteri S, Wessel D, Zuppa AF, Berg RA, Sutton RM. The Temporal Association of the COVID-19 Pandemic and Pediatric Cardiopulmonary Resuscitation Quality and Outcomes. Pediatr Crit Care Med. 2022 Sep 2. doi: 10.1097/PCC.0000000000003073. Epub ahead of print. PMID: 36053072.

Fink EL, Kochanek PM, Panigrahy A, Beers SR, Berger RP, Bayir H, Pineda J, Newth C, Topjian AA, Press CA, Maddux AB, Willyerd F, Hunt EA, Siems A, Chung MG, Smith L, Wenger J, Doughty L, Diddle JW, Patregnani J, Piantino J, Walson KH, Balakrishnan B, Meyer MT, Friess S, Maloney D, Rubin P, Haller TL, Treble-Barna A, Wang C, Clark RRSB, Fabio A; Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators. Association of Blood-Based Brain Injury Biomarker Concentrations With Outcomes After Pediatric Cardiac Arrest. JAMA Netw Open. 2022 Sep 1;5(9):e2230518. doi: 10.1001/jamanetworkopen.2022.30518. PMID: 36074465.

Neumayr TM, Alten JA, Bailly DK, Bhat PN, Brandewie KL, Diddle JW, Ghbeis M, Krawczeski CD, Mah KE, Raymond TT, Reichle G, Zang H, Selewski DT; NEPHRON Investigators. Assessment of fluid balance after neonatal cardiac surgery: a description of intake/output vs. weight-based methods. Pediatr Nephrol. 2022 Sep 6. doi: 10.1007/s00467-022-05697-w. Epub ahead of print. PMID: 36066771.

Cashen K, Reeder RW, Ahmed T, Bell MJ, Berg RA, Burns C, Carcillo JA, Carpenter TC, Dean JM, Diddle JW, Federman M, Fink EL, Frazier AH, Friess SH, Graham K, Hall M, Hehir DA, Horvat CM, Huard LL, Maa T, Manga A, McQuillen PS, Morgan RW, Mourani PM, Nadkarni VM, Naim MY, Notterman D, Palmer CA, Pollack MM, Schneiter C, Sharron MP, Srivastava N, Wessel D, Wolfe HA, Yates AR, Zuppa AF, Sutton RM, Meert KL; Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN) and National Heart Lung and Blood Institute ICU-RESUScitation Project Investigators. Sodium Bicarbonate Use During Pediatric Cardiopulmonary Resuscitation: A Secondary Analysis of the ICU-RESUScitation Project Trial. Pediatr Crit Care Med. 2022 Jul 26. doi: 10.1097/PCC.0000000000003045. Epub ahead of print. PMID: 35880872.

Alten JA, Cooper DS, Klugman D, Raymond TT, Wooten S, Garza J, Clarke-Myers K, Anderson J, Pasquali SK, Absi M, Affolter JT, Bailly DK, Bertrandt RA, Borasino S, Dewan M, Domnina Y, Lane J, McCammond AN, Mueller DM, Olive MK, Ortmann L, Prodhan P, Susaki J, Scahill C, Schroeder LW, Werho DK, Zaccagni H, Zhang W, Banerjee M, Gaies M for the PC4 CAP collaborators (including Diddle JW). Preventing Cardiac Arrest in the Pediatric Cardiac Intensive Care Unit Through Multicenter Collaboration. JAMA Pediatr. 2022 Jul 5.

Sutton RM, Wolfe HA, Reeder RW, Ahmed T, Bishop R, Bochkoris M, Burns C, Diddle JW, Federman M, Fernandez R, Franzon D, Frazier AH, Friess SH, Graham K, Hehir D, Horvat CM, Huard LL, Landis WP, Maa T, Manga A, Morgan RW, Nadkarni VM, Naim MY, Palmer CA, Schneiter C, Sharron MP, Siems A, Srivastava N, Tabbutt S, Tilford B, Viteri S, Berg RA, Bell MJ, Carcillo JA, Carpenter TC, Dean JM, Fink EL, Hall M, McQuillen PS, Meert KL, Mourani PM, Notterman D, Pollack MM, Sapru A, Wessel D, Yates AR, Zuppa AF. Effect of Physiologic Point-of-Care Cardiopulmonary Resuscitation Training on Survival with Favorable Neurological Outcome in Cardiac Arrest in Pediatric ICUs: A Randomized Clinical Trial. JAMA. 2022 Mar 8;327(10):934-945.

Piantino JA, Ruzas CM, Press CA, Subramanian S, Balkrishnan B, Panigraphy A, Pettersson D, Maloney JA, Vossough A, Topjian A, Kirschen MP, Doughty L, Chung MG, Maloney D, Haller T, Fabio A, Fink EL, and the POCCA Investigators (including Diddle JW).  Use of Magnetic Resonance Imaging in Neuroprognostication after Pediatric Cardiac Arrest: Survey of Current Practices. 2022 Jun 20;134:45-51. doi: 10.1016/j.pediatrneurol.2022.06.011.

Riley CM, Diddle JW, Harlow A, Klem K, Patregnani J, Hochberg E, Cheng JJ, Bhattarai S, Hom L, Fortkiewicz JM, Klugman D. Shifting the Paradigm: A Quality Improvement Approach to Proactive Cardiac Arrest Reduction in the Pediatric Cardiac Intensive Care Unit. Pediatr Qual Saf. 2022 Jan 21;7(1):e525.

Bailly D, Alten JA, Gist KM, Mah KE, Kwiatkowski DM, Valentine KM, Diddle JW, Tadphale S, Clark S, Selewski DT, Banerjee M, Reichle G, Lin P, Gaies M, Blinder JJ.  Fluid Accumulation after Neonatal Congenital Cardiac Surgery: Clinical Implications and Outcomes. Ann Thorac Surg. 2022 Mar 1:S0003-4975(22)00285-5.

2021

Sasaki J, Rodriguez Z, Alten JA, Rahman AF, Reichle G, Lin P, Banerjee M, Selewski D, Gaies M, Hock KM, Borasino S, Gist KM, and the NEPHRON Collaborative (including Diddle JW).  Epidemiology of Acute Kidney Injury After Cardiac Surgery Without Cardiopulmonary Bypass. Ann Thorac Surg. 2021 Oct 20;S0003-4975(21)01745-8.

Alten JA, Cooper DS, Blinder JJ, Selewski DT, Tabbutt S, Sasaki J, Gaies MG, Bertrandt RA, Smith AH, Reichle G, Gist KM, Banerjee M, Zhang W, Hock KM, Borasino S, and the NEPHRON Collaborative (including Diddle JW). Epidemiology of Acute Kidney Injury after Neonatal Cardiac Surgery: A Report from the Multicenter Neonatal and Pediatric Heart and Renal Outcomes Network.  Crit Care Med. 2021 Oct 1;49(10):e941-e951.

2020

Diddle JW, Riley CM, Hom LA, Klugman D. Open Hearts: Sharing Data to Improve Outcomes in Congenital Heart Disease. Curr Treat Options Peds. 6, 263-273 (2020).

Fink EL, Clark RSB, Panigraphy A, Berger R, Wisnowski J, Bluml S, Maloney D, Rubin P, Haller T, Bayir H, Beers SR, Kochanek PM, Fabio A, and the POCCA Investigators (including Diddle JW).  Personalising Outcomes after Child Cardiac Arrest (POCCA): Design and Recruitment Challenges of a Mulicentre, Observational Study. BMJ Open. 2020 Oct 27;10(10):e039323.

Landis WP, Morgan RW, Reeder RW, Graham K, Siems A, Diddle JW, Pollack MM, Maa T, Fernandez RP, Yates AR, Tilford B, Ahmed T, Meert KL, Schneiter C, Bishop R, Mourani PM, Naim MY, Friess S, Burns C, Manga A, Franzon D, Tabbutt S, McQuillen PS, Horvat C, Bochkoris M, Carcillo JA, Huard L, Federman M, Sapru A, Viteri S, Hehir DA, Notterman DA, Holubkov R, Dean JM, Nadkarni VM, Berg RA, Wolfe HA, Sutton RM; Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN), and the National Heart, Lung, and Blood Institute ICU-RESUScitation Project. Variability in Chest Compression Rate Calculations during Pediatric Cardiopulmonary Resuscitation. Resuscitation. 2020 Feb; 149:127-133.

2018

Reeder RW, Girling A, Wolfe H, Holubkov R, Berg RA, Naim MY, Meert KL, Tilford B, Carcillo JA, Hamilton M, Bochkoris M, Hall M, Maa T, Yates AR, Sapru A, Kelly R, Federman M, Michael Dean J, McQuillen PS, Franzon D, Pollack MM, Siems A, Diddle J, Wessel DL, Mourani PM, Zebuhr C, Bishop R, Friess S, Burns C, Viteri S, Hehir DA, Whitney Coleman R, Jenkins TL, Notterman DA, Tamburro RF, Sutton RM; Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN).  Improving outcomes from pediatric cardiac arrest - the ICU-RESUScitation project: a study protocol for a randomized controlled trial. Trials. 2018 Apr; 19(1):213.

Brown KM, Mudd SS, Hunt EA, Perretta JS, Shilkofski NA, Diddle JW, Yurasek G, Bembea M, Duval-Arnould J, McMillan KN. A Multi-institutional simulation bootcamp for pediatric cardiac critical care nurse practitioners.  Pediatr Crit Care Med. 2018 June;19(6):564-71.

2015

Diddle JW, Almodovar MC, Rajagopal SK, Rycus PT, Thiagarajan RR. Extracorporeal membrane oxygenation for the support of adults with acute myocarditis. Crit Care Med. 2015 May; 43(5): 1016-25.

2010

Maron GM, Clara AW, Diddle JW, Pleites EB, Miller L, MacDonald G, Adderson EE.  Association between nutritional status and severity of dengue infection in children in El Salvador.  Am J Trop Med Hyg. 2010 Feb; 82(2):324-9.

Abstracts

2022

Cashen K, Meert K, Reeder R, Berg R, Cooper K, Diddle JW, Graham K, Horvat C, Kirkpatrick T, Morgan R, Nadkarni V, Page K, Danna Q, Wolfe H, Yates A, Sutton R. Caution for Calcium Use During Pediatric CPR: Do Selected Resuscitation Scenarios Benefit?  SCCM April 2022.

2021

Sutton RM, Wolfe HA, Reeder RW, Ahmed T, Bell M, Bishop R, Bochkoris M, Burns C, Carcillo J, Carpenter T, Dean JM, Diddle JW, Federman M, Fernandez RP, Fink EL, Franzon D, Frazier A, Friess SH, Graham K, Hall M, Hehir D, Horvat C, Huard LL, Landis WP, Maa T, Manga A, McQuillen P, Meert K, Morgan RW, Mourani P, Nadkarni VM, Naim MY, Notterman D, Palmer CA, Pollack M, Sapru A, Schneiter C, Sharron M, Siems A, Tabbutt S, Tilford B, Viteri SD, Wessel DL, Yates AR, Zuppa A, Berg, RA;. A Randomized Trial Of A Physiologic-Directed Point-of-Care Training And Debriefing Intervention For Cardiac Arrest.  AHA Resuscitation Science Symposium November 2021.

Fink E, Kochanek PM, Panigraphy A, Beers SR, Berger RP, Bayir H, Wang C, Pineda, J, Topjian AA, Maddux A, Willyerd F, Hunt EA, Chung MG, Newth C, Smith L, Doughty L, Diddle JW, Piantino J, Hallermeir Walson K, Balakrishnan B, Friess S, Siems A, Clark RM.  Personalizing Outcomes After Child Cardiac Arrest (POCCA): A Preliminary Biomarker Report.  Resuscitation Science Symposium November 2021.

Zinna A, Berg R, Nadkarni V, Wolfe H, Huard L, Diddle JW, Frazier A, Yates A, Naim M, Reeder R, Palmer C, Page K, Morgan R, Sutton R.  Physiologic Support to Initiate Chest Compressions for Nonpulseless Organized Rhythms.  SCCM February 2021.

2020

Merritt A, Herrera G, Diddle JW, Berger J. Bear Watch: Developing a Cardiac ECMO Prediction Tool. ECMO and the Advanced Therapies for Cardiac and Respiratory Failure conference, Keystone, CO, February 2020.

Books

Chapters

2018

Diddle JW, Riley C, Klugman D (2021). ‘It Takes Teamwork: Consideration of Difficult Hospital-Acquired Conditions’, in Shah RK and Godambe SA, (Eds.) Patient Safety and Quality Improvement in Healthcare: A Case-Based Approach. Springer International Publishing, pp 309-318.

Awards and Honors

2005, Distinguished Graduate Award, University of Tennessee
2003, Alpha Omega Alpha, University of Tennessee
2000-2005, Sherrill Merit Scholar, University of Tennessee
1999, Graduated with Distinction, University of Virginia
1999, Echols Scholar, Interdisciplinary Studies, University of Virginia
1995-1999, Alumni Scholar, University of Virginia

Leadership and Memberships

Memberships in Professional Organizations

2013-present, Society of Critical Care Medicine
2012-present, Pediatric Cardiac Intensive Care Society
2010-present, American College of Cardiology
2005-present, American Academy of Pediatrics