Benjamin A. Fensterheim, MD, PhD
About Benjamin A. Fensterheim
Titles
Fellow
Awards and Honors
2018, Editor-in-Chief's Pick, The Journal of Immunology
2018, Manuscript featured on the cover of The Journal of Immunology
2018, Senior Talk, Vanderbilt MSTP Retreat
2015, 2017 - Travel Award, Annual Conference on Shock
2015, VICTR VR15742 Research Grant, Vanderbilt University
Leadership and Memberships
Memberships in Professional Organizations
Alpha Omega Alpha (Member of AOA)
American Academy of Pediatrics
Shock Society
American Physician Scientists Association
Education & training
Graduate Degree
PhD in Microbiology and Immunology - Vanderbilt University School of Medicine, Nashville, TN
Medical Degree
MD - Vanderbilt University School of Medicine, Nashville, TN
Residency
Pediatrics - Children's Hospital of Philadelphia, Philadelphia, PA
Fellowship
Neonatology - Children's Hospital of Philadelphia, Philadelphia, PA
Publications
Publications
2020
Sucre J.M.S., Vickers K.C., Jetter C.S., Cutrone A., Ransom M., Anderson Z., Sheng Q., Plosa E.J., Benjamin J.T., Fensterheim B.A., Ambalavanan N., Millis B., Lee E., Zijlstra A., Blackwell T.S., Guttentag S.H.. Activated Wnt signaling after hyperoxia injury to the developing lung is mediated by mesenchymal expression of Wnt5A. American Journal of Respiratory and Critical Care Medicine. 2020, May; 201(10): 1249 - 1262. Cited in PubMed; PMID: 32023086.
2019
Hernandez A., Luan L., Stothers C.L., Patil N.K., Fults J.B., Fensterheim B.A., Guo Y., Wang J., Sherwood E.R., Bohannon J.K.. Phosphorylated Hexa-Acyl Dissaccharides Augment Host Resistance Against Common Nosocomial Pathogens. Critical Care Medicine. 2019, Nov; 47(11): e930-e938. Cited in PubMed; PMID: 31567352.
2018
Fensterheim B.A., Young J.D., Luan L., Kleinbard R.R., Stothers C.L., Patil N.K., McAtee-Pereira A.G., Guo Y., Trenary I., Fults J.B., Hernandez A., Williams D.L., Sherwood E.R., Bohannon J.K. The TLR4 agonist Monophosphoryl Lipid A Drives Broad Resistance to Infection via Dynamic Reprogramming of Macrophage Metabolism. The Journal of Immunology. 2018, Jun; 200(11): 3777-3789. Cited in PubMed; PMID: 29686054.
Stothers C.L., Luan L., Fensterheim B.A., Bohannon J.K.. Hypoxia-Inducible Factor-1alpha Regulation of Myeloid Cells. Journal of Molecular Medicine. 2018, Dec; 96(12): 1293-1306. Cited in PubMed; PMID: 30386909.
2017
Fensterheim B.A., Guo Y., Sherwood E.R., Bohannon J.K. The Cytokine Response to Lipopolysaccharide Does NotPredict the Host Response to Infection. The Journal of Immunology. 2017, Mar; 198(8): 3264-3273. Cited in PubMed; PMID: 28275139.
Guo Y., Luan L., Patil N.K., Wang J., Bohannon J.K., Rabacal W., Fensterheim B.A., Hernandez A., Sherwood E.R. IL-15 Enables Septic Shock by Maintaining NK Cell Integrity and Function. The Journal of Immunology. 2017, Feb; 198(3): 1320-1333. Cited in PubMed; PMID: 28031340.
Luan L., Patil N.K., Guo Y., Hernandez A., Bohannon J.K., Fensterheim B.A., Wang J., Xu Y., Enkhbaatar P., Stark R., Sherwood E.R. Comparative Transcriptome Profiles of Human Blood in Response to the Toll-like Receptor 4 Ligands Lipopolysaccharide and Monophosphoryl Lipid A. Scientific Reports. 2017, Jan; 7(0): 40050. Cited in PubMed; PMID: 28053314.
2016
Hernandez A., Bohannon J.K., Luan L., Fensterheim B.A., Guo Y., Patil N.K., McAdams C., Wang J., Sherwood E.R. The role of MyD88- and TRIF-dependent signaling in monophosphoryl lipid A-induced expansion and recruitment of innate immunocytes. Journal of Leukocyte Biology. 2016, Dec; 100(6): 1311-1322. Cited in PubMed; PMID: 27354411.
Nyhoff L.E., Barron B., Johnson E.M., Bonami R.H., Maseda D., Fensterheim B.A., Han W., Blackwell T.S., Crofford L., Kendall P.L. Bruton's Tyrosine Kinase Deficiency Inhibits Autoimmune Arthritis in Mice but Fails to Block Immune Complex-Mediated Inflammatory Arthritis. Arthritis & Rheumatology. 2016, Aug; 68(8): 1856-1868. Cited in PubMed; PMID: 26945549.
Patil N.K., Luan L., Bohannon J.K., Guo Y., Hernandez A., Fensterheim B.A., Sherwood E.R. IL-15 Superagonist Expands mCD8+ T, NK and NKT Cells after Burn Injury but Fails to Improve Outcome during Burn Wound Infection. PLoS One. 2016, Feb; 11(2): e0148452. Cited in PubMed; PMID: 26859674.
2015
Bohannon J.K., Luan L., Hernandez A., Afzal A., Guo Y., Patil N.K., Fensterheim B.A., Sherwood E.R. Role of G-CSF in monophosphoryl lipid A-mediated augmentation of neutrophil functions after burn injury. Journal of Leukocyte Biology. 2015, Nov; 99(4): 629-640. Cited in PubMed; PMID: 26538529.
Guo Y., Luan L., Rabacal W., Bohannon J.K., Fensterheim B.A., Hernandez A., Sherwood E.R. IL-15 Superagonist-mediated Immunotoxicity: Role of NK Cells and Interferon-gamma. The Journal of Immunology. 2015, Sep; 195(5): 2353-2364. Cited in PubMed; PMID: 26216888.
Stark R., Koch S.R., Hyehun C., Fensterheim B.A., Lamb F.S., Sherwood E.R. Endothelial cell tolerance to lipopolysaccharide challenge is induced by Monophosphoryl lipid A. Clinical Science. 2015, Dec; 130(6): 451-461. Cited in PubMed; PMID: 26669797.
2011
Gittis A.H., Leventhal D.K., Fensterheim B.A., Pettibone J.R., Berke J.D., Kreitzer A.C. Selective inhibition of striatal fast-spiking interneurons causes dyskinesias. The Journal of Neuroscience. 2011, Nov; 31(44): 15727-15731. Cited in PubMed; PMID: 22049415.