John Flibotte, MD John Flibotte, MD, is an attending neonatologist in the Division of Neonatology and Co-medical Director of the Neonatal Neurocritical Care Program at Children's Hospital of Philadelphia. Areas of Expertise: Infant brain injury, Neonatal neurocritical care, Neuroimaging Locations: Main Campus; CHOP Newborn Care at the Hospital of the University of Pennsylvania Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467) Background I am a neonatologist with longstanding interest in the neurosciences. I am continuing my research development under the mentorship of Robert G. Kalb, MD, using C. elegans (a worm) to model hypoxic injury in developing animals. The relationship between evolving oxygen-sensing ability and hypoxic injury is not well studied. Currently, we are using the worm to begin to address this question and investigate whether intercellular signaling events influence whole animal survival and neural injury. My ultimate goal is to leverage this information towards the development of neuroprotective therapies for brain-injured infants. Education and Training Medical SchoolMD - Harvard Medical School, Boston, MA InternshipPediatrics - The Children's Hospital of Philadelphia, Philadelphia, PA ResidencyPediatrics - The Children's Hospital of Philadelphia, Philadelphia, PA FellowshipNeonatology - The Children's Hospital of Philadelphia, Philadelphia, PA Additional TrainingNeonatology Research Fellow - The Children's Hospital of Philadelphia, Philadelphia, PA Board CertificationNeonatal-Perinatal MedicinePediatrics Titles and Academic Titles Co-medical Director, Neonatal Neurocritical Care ProgramAttending NeonatologistAssistant Professor of Clinical Pediatrics, Perelman School of Medicine at the University of Pennsylvania Departments and Services Division of Neonatology Center for Fetal Diagnosis and TreatmentNeonatal Neurocritical Care ProgramNewborn/Infant Intensive Care Unit (N/IICU) Research Interests Oxygen sensing and molecular response to hypoxia Mechanisms of neuronal injury after hypoxia Neural development after hypoxic injury Model organisms Publications Papers2013 Flibotte JJ, Lee GE, Buser GL, et al. (2013) “Infertility, In Vitro Fertilization, and Emerging Congenital Tuberculosis.” J. Perinatology, 33: 565-568. Abstracts2014 Flibotte J, Kalb RG: Neural oxygen sensing and neuropeptide signaling influence survival after anoxia in C. elegans. Vancouver, Canada, 5/6/2014. [poster presentation] Pediatric Academic Societies/Asian Society for Pediatric Research Annual Meeting 2014. 2012 Flibotte J & Kalb RG (2012) “Oxygen Sensing Neurons and Selective Neuronal Vulnerability in C. elegans.” Perinatal and Developmental Symposium, Aspen, CO, 6/8/2012. [platform presentation] Flibotte J, Lee GE, Buser G, Sen S, Chandra S, Baorto EP, Feja KN, Tolan RW, McSherry GD, Nolan SM, Zhang H (2012) “Congenital Tuberculosis in Five Neonates Conceived by In Vitro Fertilization.” Pediatric Academic Societies Annual Meeting, Boston, MA, 4/28-5/1/2012. [poster presentation] Flibotte J, Lee GE, Buser G, Sen S, Chandra S, Baorto EP, Feja KN, Tolan RW, McSherry GD, Nolan SM, Zhang H (2012) “Congenital Tuberculosis in Five Neonates Conceived by In Vitro Fertilization.” Eastern Society for Pediatric Research Annual Meeting, Philadelphia, PA, 3/30-4/1/2012. [poster presentation] 2011 Lee GE, Flibotte J, Buser G, Nolan S, Zhang H, Baorto EP, McSherry GD, Feja KN, Tolan RW (2011) “Congenital Tuberculosis Following In Vitro Fertilization: Case Series of Five Indian Infants from New Jersey.” Infectious Diseases Society of America Annual Meeting, Boston, MA, 10/20-10/23/2011. BooksFlibotte J (2011). Gastrointestinal disorders. In T Florin and S Ludwig (Eds.), Netter’s Pediatrics (pp. 652-657). Oxford: Elsevier. Editorial and Academic Positions Academic and institutional committees 2012-present, Fellow representative. Trainees and Early Career Neonatologists, American Academy of Pediatrics 2011-present, Resident Lecture Committee 2011-2013, Neonatology-Perinatology Fellowship Improvement Committee