John Flibotte, MD

John Flibotte, MD

John Flibotte, MD, is an attending neonatologist in the Division of Neonatology and Co-medical Director of the Neonatal Neurocritical Care Program at Children's Hospital of Philadelphia.

Areas of Expertise: Infant brain injury, Neonatal neurocritical care, Neuroimaging
Locations: Main Campus; CHOP Newborn Care at the Hospital of the University of Pennsylvania
Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

Background

I am a neonatologist with longstanding interest in the neurosciences. I am continuing my research development under the mentorship of Robert G. Kalb, MD, using C. elegans (a worm) to model hypoxic injury in developing animals.

The relationship between evolving oxygen-sensing ability and hypoxic injury is not well studied. Currently, we are using the worm to begin to address this question and investigate whether intercellular signaling events influence whole animal survival and neural injury.

My ultimate goal is to leverage this information towards the development of neuroprotective therapies for brain-injured infants.

Education and Training

Medical School

MD - Harvard Medical School, Boston, MA

Internship

Pediatrics - The Children's Hospital of Philadelphia, Philadelphia, PA

Residency

Pediatrics - The Children's Hospital of Philadelphia, Philadelphia, PA

Fellowship

Neonatology - The Children's Hospital of Philadelphia, Philadelphia, PA

Additional Training

Neonatology Research Fellow - The Children's Hospital of Philadelphia, Philadelphia, PA

Board Certification

Neonatal-Perinatal Medicine
Pediatrics

Titles and Academic Titles

Co-medical Director, Neonatal Neurocritical Care Program

Attending Neonatologist

Assistant Professor of Clinical Pediatrics, Perelman School of Medicine at the University of Pennsylvania

Departments and Services

Research Interests

Oxygen sensing and molecular response to hypoxia
Mechanisms of neuronal injury after hypoxia
Neural development after hypoxic injury
Model organisms

 

Publications

Papers

2013

Flibotte JJ, Lee GE, Buser GL, et al. (2013) “Infertility, In Vitro Fertilization, and Emerging Congenital Tuberculosis.” J. Perinatology, 33: 565-568.

Abstracts

2014

Flibotte J, Kalb RG: Neural oxygen sensing and neuropeptide signaling influence survival after anoxia in C. elegans. Vancouver, Canada, 5/6/2014. [poster presentation] Pediatric Academic Societies/Asian Society for Pediatric Research Annual Meeting 2014.

2012

Flibotte J & Kalb RG (2012) “Oxygen Sensing Neurons and Selective Neuronal Vulnerability in C. elegans.” Perinatal and Developmental Symposium, Aspen, CO, 6/8/2012. [platform presentation]

Flibotte J, Lee GE, Buser G, Sen S, Chandra S, Baorto EP, Feja KN, Tolan RW, McSherry GD, Nolan SM, Zhang H (2012) “Congenital Tuberculosis in Five Neonates Conceived by In Vitro Fertilization.” Pediatric Academic Societies Annual Meeting, Boston, MA, 4/28-5/1/2012. [poster presentation]

Flibotte J, Lee GE, Buser G, Sen S, Chandra S, Baorto EP, Feja KN, Tolan RW, McSherry GD, Nolan SM, Zhang H (2012) “Congenital Tuberculosis in Five Neonates Conceived by In Vitro Fertilization.” Eastern Society for Pediatric Research Annual Meeting, Philadelphia, PA, 3/30-4/1/2012. [poster presentation]

2011

Lee GE, Flibotte J, Buser G, Nolan S, Zhang H, Baorto EP, McSherry GD, Feja KN, Tolan RW (2011) “Congenital Tuberculosis Following In Vitro Fertilization: Case Series of Five Indian Infants from New Jersey.” Infectious Diseases Society of America Annual Meeting, Boston, MA, 10/20-10/23/2011.

Books

Flibotte J (2011). Gastrointestinal disorders. In T Florin and S Ludwig (Eds.), Netter’s Pediatrics (pp. 652-657). Oxford: Elsevier.

Editorial and Academic Positions

Academic and institutional committees

2012-present, Fellow representative. Trainees and Early Career Neonatologists, American Academy of Pediatrics
2011-present, Resident Lecture Committee
2011-2013, Neonatology-Perinatology Fellowship Improvement Committee