Scott Gordon, MD, PhD
Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)
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MD - Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA
Pediatrics - The Children’s Hospital of Philadelphia, Philadelphia, PA
Neonatal-Perinatal Medicine - The Children's Hospital of Philadelphia, Philadelphia, PA
Pediatrics – American Board of Pediatrics
PhD in Immunology - Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
Assistant Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania
Gordon SM, Nishiguchi MA, Chase JM, Mani S, Mainigi MA, Behrens EM. IFNs Drive Development of Novel IL-15–Responsive Macrophages. 2020. JImmunol.https://doi.org/10.4049/jimmunol.2000184.
Johannesson, L, Testa, G, Flyckt, R, Farrell R, Quintini C, Wall A, O’Neill K, Tzakis A, Richards EG, Gordon SM, Porrett PM. Guidelines for standardized nomenclature and reporting in uterus transplantation: An opinion from the United States Uterus Transplant Consortium. Am J Transplant. 2020. https://doi.org/10.1111/ajt.15973.
Gordon SM, Srinivasan L, Taylor DM, Master SR, Tremoglie, MA, Hankeova A, Flannery DD, Abbasi S, Fitzgerald JC, Harris MC. Derivation of a metabolic signature associated with bacterial meningitis in infants. 2020. Pediatr Res. 88, 184–191. https://doi.org/10.1038/s41390-020-0816-7
Gordon SM, Srinivasan L and Harris MC. Neonatal Meningitis: Overcoming Challenges in Diagnosis, Prognosis, and Treatment with Omics. 2017. Front. Pediatr. 5:139. https://doi.org/10.3389/fped.2017.00139
Gordon, S.M., Srinivasan, L., and Harris, M.C. (2017). Neonatal Meningitis: Overcoming Challenges in Diagnosis, Prognosis, and Treatment with Omics. Front Pediatr. 5, 139.
Paley Michael A, Gordon Scott M, Bikoff Elizabeth K, Robertson Elizabeth J, Wherry E John, Reiner Steven L: Technical Advance: Fluorescent reporter reveals insights into eomesodermin biology in cytotoxic lymphocytes. Journal of leukocyte biology 93(2): 307-15, Feb 2013.
Gordon Scott M, Chaix Julie, Rupp Levi J, Wu Junmin, Madera Sharline, Sun Joseph C, Lindsten Tullia, Reiner Steven L: The transcription factors T-bet and Eomes control key checkpoints of natural killer cell maturation. Immunity 36(1): 55-67, Jan 2012.
Qui Harry Z, Hagymasi Adam T, Bandyopadhyay Suman, St Rose Marie-Clare, Ramanarasimhaiah Raghunath, Ménoret Antoine, Mittler Robert S, Gordon Scott M, Reiner Steven L, Vella Anthony T, Adler Adam J: CD134 plus CD137 dual costimulation induces Eomesodermin in CD4 T cells to program cytotoxic Th1 differentiation. Journal of immunology (Baltimore, Md. : 1950) 187(7): 3555-64, Oct 2011.
Gordon Scott M, Carty Shannon A, Kim Jiyeon S, Zou Tao, Smith-Garvin Jennifer, Alonzo Eric S, Haimm Ethan, Sant'Angelo Derek B, Koretzky Gary A, Reiner Steven L, Jordan Martha S: Requirements for eomesodermin and promyelocytic leukemia zinc finger in the development of innate-like CD8+ T cells. Journal of immunology (Baltimore, Md. : 1950) 186(8): 4573-8, Apr 2011.
Kinjyo Ichiko, Gordon Scott M, Intlekofer Andrew M, Dowdell Kennichi, Mooney Erin C, Caricchio Roberto, Grupp Stephan A, Teachey David T, Rao V Koneti, Lindsten Tullia, Reiner Steven L: Cutting edge: Lymphoproliferation caused by Fas deficiency is dependent on the transcription factor eomesodermin. Journal of immunology (Baltimore, Md. : 1950) 185(12): 7151-5, Dec 2010.
Banerjee Arnob, Gordon Scott M, Intlekofer Andrew M, Paley Michael A, Mooney Erin C, Lindsten Tulia, Wherry E John, Reiner Steven L: Cutting edge: The transcription factor eomesodermin enables CD8+ T cells to compete for the memory cell niche. Journal of immunology (Baltimore, Md. : 1950) 185(9): 4988-92, Nov 2010.
Intlekofer Andrew M, Banerjee Arnob, Takemoto Naofumi, Gordon Scott M, Dejong Caitlin S, Shin Haina, Hunter Christopher A, Wherry E John, Lindsten Tullia, Reiner Steven L: Anomalous type 17 response to viral infection by CD8+ T cells lacking T-bet and eomesodermin. Science (New York, N.Y.) 321(5887): 408-11, Jul 2008.
Maruyama Rika, Velarde Nathalie V, Klancer Richard, Gordon Scott, Kadandale Pavan, Parry Jean M, Hang Julie S, Rubin Jacob, Stewart-Michaelis Allison, Schweinsberg Peter, Grant Barth D, Piano Fabio, Sugimoto Asako, Singson Andrew: EGG-3 regulates cell-surface and cortex rearrangements during egg activation in Caenorhabditis elegans. Current biology : CB 17(18): 1555-60, Sep 2007.
Kadandale Pavan, Stewart-Michaelis Allison, Gordon Scott, Rubin Jacob, Klancer Richard, Schweinsberg Peter, Grant Barth D, Singson Andrew: The egg surface LDL receptor repeat-containing proteins EGG-1 and EGG-2 are required for fertilization in Caenorhabditis elegans. Current biology : CB 15(24): 2222-9, Dec 2005.
Gordon S. "Development of Novel CD122+ Macrophages Unde the Direction of Type i Interferon", St. Christopher's Hospital for Children, Section of Neonatal Medicine. June 2018.
Gordon S. Analysis of Cerebrospinal Fluid Reveals a Metabolic Signature of Bacterial Meningitis in Infants", Platform Presentation, Eastern Society for Pediatric Research Annual Meeting. Mar 2016.
2019, Fellows’ Basic Research Award, Society for Pediatric Research
2018, Foerderer Award, The Children's Hospital of Philadelphia Research Institute
2018, Marshall Klaus Perinatal Research Award, American Academy of Pediatrics
2014, Resident Research Grant, American Academy of Pediatrics
2012, Mary Ellis Bell Prize, Perelman School of Medicine
2011, Trainee Abstract Award, The American Associations of Immunologists
2016-present, The American Academy of Pediatrics
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