Kathryn E. Hamilton, PhD
Areas of expertise: Gastrointestinal Basic/Translational Research
About Kathryn E. Hamilton, PhD
Titles
Scientist
Associate Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania
Awards and Honors
2024, American Gastroenterological Association Young Investigator Award
2024, Elected Member, Society for Pediatric Research
2024, Young Investigator Award, American Gastroenterological Association
2022, American Physiological Society Gastrointestinal and Liver Section New Investigator Award
2022, Award for Excellence in Mentoring Research Trainees, Children's Hospital of Philadelphia
2022, New Investigator Award, American Physiological Society Gastrointestinal and Liver Section
2019, Participant, Dr. Edward S. Cooper Leadership Development Program, University of Pennsylvania Perelman School of Medicine
2018, American Gastroenterological Association (AGA) Research Institute Research Policy Committee, Awards Panel Sub-Committee (nomination-based appointment)
2018-2020, American Gastroenterological Association (AGA) Institute Council Nominating Committee Member (elected position)
2016, American Gastroenterological Association (AGA) Women’s Leadership Conference, Dallas, TX
2016, Women's Leadership Conference, American Gastroenterological Association, Dallas, TX
2015, American Society for Investigative Pathology (ASIP) Research Travel Award, Experimental Biology Meeting, Boston, MA
2014, American Physiological Society GI & Liver Section Takeda Travel Award, Experimental Biology Meeting, San Diego, CA
2014, American Gastroenterological Association/American Association for the Study of Liver Diseases Academic Skills Workshop, San Diego, CA
2012, American Gastroenterological Association Research Foundation Horizon Pharma Fellow Abstract Prize Recipient, Freston Conference, Chicago, IL
2010, University of North Carolina Graduate Education Advancement Board Impact Award, Chapel Hill, NC
2009, American Physiological Society GI & Liver Section Research Recognition Award, Experimental Biology Meeting, New Orleans, LA
2009, American Physiological Society GI & Liver Section Graduate Student Poster Competition Award, Experimental Biology Meeting, New Orleans, LA
Leadership and Memberships
Leadership
2015- present Faculty, Institute for Translational Medicine and Therapeutics (ITMAT), University of Pennsylvania School of Medicine
2017- present Faculty, Institute for Regenerative Medicine (IRM), University of Pennsylvania School of Medicine
2019- present Co-Director, Gastrointestinal Epithelial Modeling Program, Children's Hospital of Philadelphia
2020- present Co-Leader, Intestinal Biology Theme, NIH/NIDDK P30 Center for Molecular Studies in Digestive and Liver Diseases, University of Pennsylvania Perelman School of Medicine
2025- present Assistant Director, Recruitment and Admissions, University of Pennsylvania Perelman School of Medicine Office of Research Trainee Affairs
Memberships
2009-Present American Physiological Society
- Member, 2009-present
- Member, Programming Committee, Gastrointestinal & Liver Section, 2017-present
- Elected Member, Steering Committee, Gastrointestinal & Liver Section, 2021-2024
- Co-Chair, Programming Committee, Gastrointestinal & Liver Section, 2024-present
- Member, Physiology Summit Leadership Committee, 2024-present
2012-Present American Gastroenterological Association
- Member, 2012-present
- Member, Council Abstract Review Committee, Molecular Mechanisms of Growth and Development of the GI Tract, Liver and Pancreas, 2017-present
- Elected Member, Institute Council Nominating Committee, 2018-2020
- Member, Study Section, Foundation Research Awards Panel, 2018-2024
- Abstract Reviewer, Digestive Diseases Week, Foundation Research Awards Panel, 2018-2024
2014-Present Crohn's and Colitis Foundation
- Member, 2014-present
- Member (Ad hoc), Research Training Award Committee, 2022-2024
Editorial and Academic Positions
Editorial Positions
2012-Present Peer Reviewer: American Journal of Physiology, Gastrointestinal and Liver Physiology
2012-present Editorial Board Member: American Journal of Physiology, Gastrointestinal and Liver Physiology
2015-Present Peer Reviewer: Molecular Cancer Research
2015-Present Peer Reviewer: Scientific Reports
2016-Present Peer Reviewer: JCI Insights
2017-2018 Section Editor: Basic Science Foundations in Colorectal Cancer, Current Colorectal Cancer Reports
2017-Present Peer Reviewer: Cell and Molecular Gastroenterology and Hepatology
2018-Present Peer Reviewer: Biochemistry Journal
2018-Present Peer Reviewer: Experimental Cell Research
2019-Present Peer Reviewer: Gastroenterology
2023-Present Peer Reviewer: mBio
2023-Present Peer Reviewer: Cell Stem Cell
2024-Present Associate Editor: Cell and Molecular Gastroenterology and Hepatology
Education & training
Undergraduate Degree
BA in Biology with concentration in Biotechnology - Assumption College, Worcester, MA
Graduate Degree
PhD in Cell and Molecular Physiology - University of North Carolina, Chapel Hill, NC
Fellowship
Postdoctoral Fellow - University of Pennsylvania, Philadelphia, PA
Publications
PubMed
Lectures by Invitation
2023
Kathryn E. Hamilton. "IMP-lications for cell plasticity in the regenerating intestine", Oregon Health Sciences University Bench to Bedside Seminar Series, Portland, OR. Oct 2023.
Kathryn E. Hamilton. "A Crohn's disease epithelial stem cell atlas reveals sustained inflammatory progenitor cell states", Helmsley Gut Cell Atlas Annual Convening, New York, NY. Sept 2023.
Kathryn E. Hamilton. "Autophagy as a way to identify intestinal stem cell populations", 2023 Digestive Diseases Week, Research Symposium Invited Presentation, Chicago, IL. May 2023.
Kathryn E. Hamilton. "Implicating autophagy in intestinal tissue plasticity", Lancaster University, United Kingdom, Department of Biomedical and Life Sciences, virtual. Feb 2023.
Kathryn E. Hamilton. "Implicating autophagy in intestinal tissue plasticity", Texas Medical Center/Baylor College of Medicine NIH P30 Digestive Diseases Research Center, Houston, TX. Feb 2023.
Kathryn E. Hamilton. "Implicating autophagy in intestinal tissue plasticity", University of Illinois, Chicago, Department of Medicine, Division of Gastroenterology and Hepatology, virtual. Jan 2023.
2022
Kathryn E. Hamilton. "Using Organoids to Study Pediatric Inflammatory Bowel Disease", 2022 James W. Freston Conference: Gastrointestinal Organoids and Engineered Organ Systems, Research Symposium Invited Presentation, Washington, DC. Oct 2022.
Kathryn E. Hamilton. "Understanding Intestinal Epithelial Stem Cells in Children and Adults with Crohn's Disease", Helmsley Charitable Trust Gut Cell Atlas Annual Convening, Research Symposium Invited Presentation, New York, NY. Sept 2022.
Kathryn E. Hamilton. "Dynamic Regulation of Intestinal Tissue Repair via RNA Binding Protein IMP1/IGF2BP1", Gordon Research Conference: Post-transcriptional Gene Regulation, Invited Presentation, Sunday River, ME. Jul 2022.
Kathryn E. Hamilton. "Understanding durable epithelial changes in pediatric inflammatory bowel disease", 2022 Digestive Diseases Week, Research Forum Invited Presentation, San Diego, CA. May 2022.
Kathryn E. Hamilton. "IMP-lications for post-transcriptional gene regulation in intestinal epithelial homeostasis", Experimental Biology Annual Meeting, Research Symposium Invited Presentation, Philadelphia PA. Apr 2022.
2021
Kathryn E. Hamilton. "IMP-licating RNA binding proteins in intestinal epithelial regeneration", RNA Society's RNA Collaborative Seminar Series, virtual. Dec 2021.