David H. Jang, MD, MSc

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David H. Jang, MD, MSc, is a medical toxicologist in the Poison Control Center at Children's Hospital of Philadelphia.

Locations: Main Campus
Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

Education and Training

Medical School

MD - Tufts University School of Medicine, Boston, MA

Residency

Emergency Medicine - University of Pittsburgh Medical Center, Pittsburgh, PA

Fellowship

Medical Toxicology - New York University/New York City, Poison Control Center, New York, NY

Board Certification

Emergency Medicine
Medical Toxicology

Graduate Degree

MSc in Clinical Investigation - New York University School of Medicine/Clinical and Translational Science Institute, New York, NY

Titles and Academic Titles

Medical Toxicologist

Departments and Services

Publications

Papers

2016

Jang DH, Greenwood J, Spyres MB, et al. Bench to Bedside: Measurement of Mitochondrial Respiration in Emergency Medicine. J Intensive Care Med. 2016 Jul 21.

Jang DH, Shofer FS, Weiss SL, et al. Impairment of Mitochondrial Respiration Following Ex-vivo Cyanide Exposure in Peripheral Blood Mononuclear Cells. Clin Tox. 2016 Feb 5:1-5. 26846815.

2015

Jang DH, Lampe J, Becker LB. The Potential Application of Mitochondrial Medicine in Toxicologic Poisoning. J Med Toxicol. 2015 Jun;11(2):201-7. PMID: 25907836.

2014

Jang DH, Donovan SP, Bania TC, et al. Efficacy of Methylene Blue in an Experimental Model of Calcium Channel Blocker Induced Shock.  Ann Emerg Med. Oct 23th 2014. PMID: 25441767.

Jang DH, Spyres MB, Fox L, et al. Toxin-Induced Cardiovascular Failure. Emerg Med Clin North Am. 2014 Feb;32(1):79-102. PMID: 24275170.

2013

Jang DH, Donovan SP, Bania TC, et al. The novel development of an experimental model of dihydropyridine calcium channel blocker poisoning using intravenous amlodipine. Int J Cardiovasc Res. 2013;Mar 29;2(2). PMID: 24416727.

Jang DH, Nelson LS, Hoffman RS. Methylene blue for distributive shock: A potential new use of an old antidote. J Med Toxicol. 2013;Sep;9(3):242-9. PMID: 23580172.

Jang DH, Nelson LS, Hoffman RS. Response to Methylene Blue Does Not Have to Be Considered Only as Rescue Therapy for Distributive Shock. J Med Toxicol. 2013 Dec;9(4):427. PMID: 24081615.

2012

Jang DH, Spyres MB, Nelson LS, et al.  An 11-year retrospective comparison of dihydropyridines and non-dihydropyridine calcium channel blockers-Meeting Abstract. Clin Tox. 2012;50(7):640-640.

Jang DH, Hoffman RS, Nelson LS. A case of near-fatal flecainide overdose in a neonate successfully treated with sodium bicarbonate. Jour of Emerg Med. 2012 Sep 12. PMID: 22981658.

Kim HK, Shawn LK, Nelson LS, Jang DH. Articles you may have missed. J Med Toxicol. 2012;8(1):83-85. PMID: 159833.

2011

Jang DH, Weaver MD, Pizon AF. In Vitro Study of N-acetylcysteine on Coagulation Factors in Plasma Samples from Healthy Subjects. J Med Toxicol. 2011. Jun 26. PMID: 22733602.

Jang DH, Rusinayk D. Impact factor Editorial.  J Med Toxicol. 2011;7(4):256-8. PMID: 21826571.

Jang DH, Hoffman RS. Heavy metal chelation in neurotoxic exposures. Neurol Clin. 2011;29(3):607-22. PMID: 21803213.

Parikh A, Jang DH, Howland MA, et al. Response to “Effect of Deferasirox on Iron Absorption in a Randomized, Placebo-Controlled, Crossover Study in a Human Model of Acute Supratherapeutic Iron Ingestion.” Ann Emerg Med.  2011;58:219-20. PMID: 21782558.

Jang DH, Hoffman RS, Chu J, et al. Fatal outcome of a propoxyphene/acetaminophen (Darvocet) overdose: Should it still be used in the United States? Ann Emerg Med. 2011;57(4):421-422. PMID: 21453827.

Pizon AF, Jang DH, Wang H. The in vitro effect of N-acetylcysteine on prothrombin time in plasma samples from healthy subjects. Acad Emerg Med. 2011;18(4):351-354. PMID: 21496136.

Jang DH, Bruccoleri R, Tolchin B, et al.  Response to "Benefit effect of naloxone in benzodiazepines intoxication: Findings of a preliminary study." Hum Exp Toxicol. 2011;30(4):343. PMID: 21056948.

Jang DH, Nelson LS, Hoffman RS. Methylene blue in the treatment of refractory shock from an amlodipine overdose. Ann Emerg Med. 2011;58(6):565-7. PMID: 21546119.

2010

Jang DH, Truegar NS, Nestor NB, et al. Status epilepticus and wide-complex tachycardia secondary to diphenhydramine overdose. Clin Toxicol (Phila). 2010;48(9):945-948. PMID: 21171853.

Jang DH. Fellows’ Perspective: The impact of a medical toxicology fellowship on the training of future emergency medicine residents. J Med Toxicol. 2010;6(4):371. PMID: 20922513.

Punja M, Jang DH, Hoffman RS. Response to “A multicenter comparison of the safety of oral versus intravenous acetylcysteine for treatment of acetaminophen overdose.” Clin Toxicol. 2010;48(7)768-769. PMID: 20849336.

Jang DH. Fellows’ Perspective: Poison control centers on the chopping block-Will this affect the training of future medical toxicology fellows? J Med Toxicol. 2010;6(3):279-280. PMID: 20556562.

Jang DH, Hoffman RS, Nelson LS. Attempted suicide, by mail order: Abrus precatorius. J Med Toxicol. 2010;6(4):427-30. PMID: 20563676.

Jang DH, Nelson LS, Hoffman RS. Letter to the Editor: Tryptase serum level as a possible indicator of scombroid syndrome. Clin Toxicol. 2010;48(5):474. PMID: 20515401.

Jang DH, Nelson LS, Hoffman RS. Images in Toxicology: Girl with constipation. Clin Toxicol. 2010;48(5):468. PMID: 20614495.

Jang DH, Nelson LS, Hoffman RS. Letter to the editor: Hydroxocobalamin and Sodium Thiosulfate Versus Sodium Nitrite and Sodium Thiosulfate in the Treatment of Acute Cyanide Toxicity in a Swine (Sus scrofa) Model. Ann Emerg Med. 2010;55(6):582. PMID: 20494232.

Jang DH, Rohe JC, Nelson LS, et al. Severe opioid withdrawal due to misuse of new combined morphine and naltrexone product (Embeda). Ann Emerg Med. 2010;55:303-304. PMID: 20171465.

Jang DH, Nelson LS.  Images in Emergency Medicine-Woman with unresponsiveness.  Ann Emerg Med. 2010;56(2):201,207. PMID: 20643271.

2008

Rittenberger J, Kelly E, Jang DH, et al.  Successful outcome utilizing hypothermia after cardiac arrest in pregnancy:  A case report.  Crit Care Med. 2008;36:1354-1356. PMID: 18379264.

Books

2011

Jang DH. Deja Review:  Emergency Medicine, 2nd ed. McGraw-Hill: New York; 2011

2007

Jang DH. Deja Review:  Emergency Medicine, 1st ed. McGraw-Hill: New York; 2007

Chapters

2014

Jang DH. Calcium Channel Blockers. Goldfrank’s Toxicologic Emergencies, 10th Edition. McGraw-Hill Publications. New York; November 2014.

Jang DH. Amphetamines. Goldfrank’s Toxicologic Emergencies, 10th Edition. McGraw-Hill Publications. New York; November 2014.

2011

Jang DH, Nelson LS. Sedative-Hypnotics. Encyclopedia of Intensive Care Medicine. Springer Publication; 2011.

2010

Jang DH, Nelson LS.  Methylxanthines. The 5 Minute Pediatric Emergency Medicine Consult, 1st ed.  Williams, & Wilkins/Wolters Kluwer Health: New York; 2010

Jang DH, Nelson LS. Anticholinergics. The 5 Minute Pediatric Emergency Medicine Consult, 1st ed.  Williams, & Wilkins/Wolters Kluwer Health: New York; 2010

Jang DH, Nelson LS. Carbon Monoxide/Cyanide. The 5 Minute Pediatric Emergency Medicine Consult, 1st ed. Williams, & Wilkins/Wolters Kluwer Health: New York; 2010 

Posters and Presentations

2016

"Bedside Measurement of Mitochondrial Dysfunction in Circulating Immune Cells in Sepsis." ePoster Presentation:  Society for Academic Emergency Medicine-May 2016 (New Orleans, Louisiana).

"Measurement of Mitochondrial Respiration as a Biomarker in Carbon Monoxide Poisoning.” ePoster Presentation:  Society for Academic Emergency Medicine-May 2016 (New Orleans, Louisiana).

2015

"Introduction to mitochondrial bioenergetics with application to acute toxicologic poisoning." ACMT Symposium North American Congress of Clinical Toxicology-October 2015 (San Francisco, California).

Invited Lectures

2016

Jang DH. Introduction to mitochondrial dysfunction in acute toxicologic poisoning. Multidisciplinary Frontiers Course. University of Pennsylvania School of Medicine. Philadelphia, PA. April 2016.

Jang DH. Clinical Approach in Medical Toxicology Course. Master of Science in Forensics Science. Philadelphia College of Osteopathic Medicine. Philadelphia, PA. April 2016.

Jang DH. Images in Medical Toxicology. Joint CHOP/HUP Grand Rounds. University of Pennsylvania. Philadelphia, PA.  March 2016.

Awards and Honors

2015, Society for Redox Biology and Medicine Research (SFRBM) Mini-Fellowship Grant

2015, Clinical "Rookie" Attending of the Year, University of Pennsylvania Department of EMC

2013, National Institutes of Health Extramural Loan Repayment Program (NIH LRP)

2013, The Regents Physician Loan Forgiveness Award, State of New York

2013, American Academy of Clinical Toxicology Research Award

2012, Clinical Attending of the Year Award: 2011-2012, NYU Emergency Medicine Residency

2012, Clinical and Translational Science Institute (CTSI) Research Fund Award, NYU CTSI

2011, American Academy of Clinical Toxicology Junior Investigator Research Grant

2010, Informa Best Presentation-XXX International Congress of the EAPCCT: Bordeaux, France

2010, Fellows Research Symposium Travel Award, American College of Medical Toxicology

2009, American Academy of Clinical Toxicology Research Award

2009, Peter Safar Award for Excellence in Research in Emergency Medicine, University of Pittsburgh

2009, Pittsburgh Emergency Medicine Foundation Research Grant

2008, Michael P. Spadafora Medical Toxicology Award, ACMT

2007-2008, Pittsburgh Emergency Medicine Foundation Research Grant

2003, Harold Williams Research Fellowship, Tufts University School of Medicine

2001, Magna cum Laude with Departmental Honors, University of Massachusetts-Amherst

2001, Phi Beta Kappa, University of Massachusetts-Amherst

2001, Robert Maxwell Williams Memorial Scholarship for Organic Chemistry

Editorial and Academic Positions

Editorial Positions

2010-present, Editorial Board Member, Journal of Medical Toxicology

Peer Reviewer

Annals of Emergency Medicine
Academic Emergency Medicine
Clinical Toxicology (formerly Journal of Toxicology/Clinical Toxicology)
Journal of Medical Toxicology

Leadership and Memberships

Memberships in Professional Organizations

2015-present, Society for Redox Biology and Medicine
2007-present, The American Academy of Clinical Toxicology
2007-present, The American College of Medical Toxicology
2006-present, Society for Academic Emergency Medicine
2005-present, American College of Emergency Physicians