Maria A. Kowalska, PhD Maria A. Kowalska, PhD, is a member of the research faculty in the Division of Hematology at The Children's Hospital of Philadelphia. Locations: Main Campus Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467) Education and Training FellowshipPostdoctoral Fellow - Thrombosis Research Center, Temple University School of Medicine, Philadelphia, PA Undergraduate DegreeBS in Physics - University of Lodz, Lodz, Poland Graduate DegreePhD in Biochemistry - University of Lodz, Lodz, Poland MS in Biophysics - University of Lodz, Lodz, Poland Titles and Academic Titles Senior Scientist Departments and Services Division of Hematology Publications Papers2016 Stasiak M, Boncela J, Perreau C, Karamanou K, Chatron-Colliet A, Proult I, Przygodzka P, Chakravarti S, Maquart F-X, Kowalska MA, Wegrowski Y and Brézillon S. Lumican inhibits SNAIL-induced melanoma cell migration specifically by blocking MMP-14 activity. PLOS One March 1 2016. PLoS One 11(3):e0150226. doi: 10.1371/journal.pone.0150226, 2016. Fuentes RE, Zaitsev S, Ahn HS, Hayes V, Kowalska M, Lambert MP, Wang Y, Siegel DL, Bougie DW, Aster RH, Myers DD, Stepanova V, Cines DB, Muzykantov VR, Poncz M. A chimeric platelet-targeted urokinase prodrug selectively blocks new thrombus formation. J Clin Invest. 126(2):483-94, 2016. 2015 Lambert MP, Meng R, Xiao L, Harper DC, Marks MS, Kowalska MA, Poncz M. Intramedullary megakaryocytes internalize released platelet factor 4 and store it in alpha granules. J Thromb Haemost. 13:1888-99. 2015. Meng R, Wu J, Harper DC, Wang Y, Kowalska MA, Abrams CS, Brass LF, Poncz M, Stalker TJ, Marks MS. Defective release of alpha granule and lysosome contents from platelets in mouse Hermasky-Pudlak syndrome models. Blood 125:1623-32, 2015.. 2014 Skewis LR, Lebedeva T, Papkov V, Thayer EC, Massefski W, Cuker A, Nagaswami C, Litvinov RI, Kowalska MA, Rauova L, Poncz M, Weisel JW, Lowery TJ, Cines DB.,T2 Magnetic Resonance: A Diagnostic Platform for Studying Integrated Hemostasis in Whole Blood—Proof of Concept. Clinical Chemistry. 60: 1174-82, 2014 . Shi G, Field DJ, Ko K, Ture S, Srivastava K, Levy S, Kowalska MA, Poncz M, Fowell DJ, and Morrell CN. Platelet factor 4 limits Th17 differentiation and cardiac allograft rejection. J Clin Invest. 124: 543-552, 2014. Kowalska MA, Zhao G, Zhai L, David G, Krishnaswamy S, Poncz M. Modulation of protein C activation by histones, platelet factor 4 and heparinoids: New insights into activated protein C formation. Arterioscler Thromb Vasc Biol. 34:120-126, 2014. BooksChapters Fukami MH, Holmsen H, Kowalska MA, Niewiarowski S: Platelet Secretion. Chapter 32. In Haemostasis and Thrombosis: Basic principles and Clinical Practice. 4th edition. Edited by RW. Colman, J. Hirsh, VJ Marder, AW Clowes, JN George. Lippincott Williams & Wilkins, 2000. Posters and PresentationsLectures by Invitation 2016 Kowalska MA. Seminar at the University of Reims, Champagne Ardenne, Laboratoire de Biochimie Médicale et de Biologie Moléculaire; 2016 May; Reims, France. Awards and Honors 2009-201, Grant-in-Aid from American Heart Association “Platelet Factor 4 in Thrombosis: Intersection of Physiology and Pathology” 2007-2009, Grant-in-Aid from American Heart Association “The role of platelet-specific chemokines in inflammation” 2002-2005, Grant-in-Aid from American Heart Association “Defining the biology of PF4” Editorial and Academic Positions Editorial Positions Reviewer Blood Journal of Thrombosis and Haemostasis Thrombosis and Haemostasis Leadership and Memberships Memberships in Professional Organizations American Society of Hematology American Heart Association International Society on Thrombosis and Haemostasis Patient Experience Ratings About the Patient Experience Rating System The Patient Experience Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question. Responses are measured on a scale of 1 to 5 with 5 being the best score. The comments are submitted by patients and families and reflect their views and opinions. The comments are not endorsed by and do not reflect the views of Children’s Hospital of Philadelphia.