Areas of Expertise:
Thalassemias, Sickle cell disease, Anemia, Iron deficiency anemia, Transfusional iron overload, General pediatric hematology
Locations:
Main Campus
MD - Columbia University College of Physicians and Surgeons, New York, NY
Pediatrics - Johns Hopkins University Hospital, Baltimore, MD
Pediatrics - Johns Hopkins University Hospital, Baltimore, MD
Pediatric Hematology/Oncology - The Children's Hospital of Philadelphia, Philadelphia, PA
Pediatric Hematology/Oncology
Director, Thalassemia Program
Attending Physician
Associate Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania
Stanley HM, Friedman D, Webb J, Kwiatkowski, JL. Transfusional Iron Overload in a Cohort of Children with Sickle Cell Disease: Impact of Magnetic Resonance Imaging, Transfusion Method, and Chelation. Pediatr Blood Cancer. 2016 Apr 21. doi: 10.1002/pbc.26017. [Epub ahead of print]. Read the abstract.
Nabavizadeh SA, Vossough A, Ichord RN, Kwiatkowski J, Pukenas BA, Smith MJ, Storm PB, Zager EL, Hurst RW. Intracranial Aneurysms in sickle cell anemia: clinical and imaging findings. J Neurointerv Surg. 2016 Apr;8(4):434-40. doi: 10.1136/neurintsurg-2014-011572. Epub 2015 Mar 19. Read the abstract.
Luchtman-Jones L, Pressel S, Hilliard L, Brown RC, Kwiatkowski JL, Davis BR, Ware RE. Effects of hydroxyurea treatment for patients with hemoglobin SC disease. Am J Hematol. 2016 Feb;91(2):238-42. doi: 10.1002/ajh.24255. Read the abstract.
Ware RE, Davis BR…Kwiatkowski JL, Jackson S…Pressel S, Adams RJ. Hydroxycarbamide versus chronic transfusion for maintenance of transcranial Doppler flow velocities in children with sickle cell anaemia-TCD with Transfusions Changing to Hydroxyurea (TWiTCH): a multicenter, open-label, phase 3, non-inferiority trial. Lancet. 2016 Feb 13;387(10019):661-70. doi: 10.1016/S0140-6736(15)01041-7. Epub 2015 Dec 6. Read the abstract.
Wood JC, Pressel S, Rogers ZR, Odame I, Kwiatkowski JL, Lee MT, Owen WC, Cohen AR, St. Pierre T, Heeney MM, Schultz WH, Davis BR, Ware RE for the TWiTCH Investigators. Liver iron concentration measurements by MRI in chronically transfused children with sickle cell anemia: baseline results from the TWiTCH trial. Am J Hematol. 2015 Sep;90(9):806-10. doi: 10.1002/ajh.24089. Read the abstract.
Morris CR, Kim HY, Klings ES, Wood J, Porter JB, Trachtenberg F, Sweeters N, Olivieri NF, Kwiatkowski JL, Virzi L, Hassell K, Taher A, Neufeld EJ, Thompson AA, Larkin S, Suh JH, Vichinsky EP, Kuypers FA for the Thalassemia Clinical Research Network. Dysregulated arginine metabolism and cardiopulmonary dysfunction in patients with thalassemia. Br J Haematol. 2015 Jun;169(6):887-98. doi: 10.1111/bjh.13452. Epub 2015 Apr 24. Read the abstract.
Belmont AP, Nossair F, Brambilla D, Friedman M, Boswinkel J, Bradford AB, and Kwiatkowski JL. Safety of deep sedation in young children with sickle cell disease: a retrospective cohort study. J Pediatr. 2015 May;166(5):1226-32. doi: 10.1016/j.jpeds.2015.01.054. Read the abstract
Tubman VN, Fung EB, Vogiatzi M, Thompson AA, Rogers ZR, Neufeld EJ, Kwiatkowski JL, for the Thalassemia Clinical Research Network. Guidelines for the Standard Monitoring of Patients with Thalassemia: Report of the Thalassemia Longitudinal Cohort. J Pediatr Hematol Oncol. 2015 Apr;37(3):e162-9. doi: 10.1097/MPH.0000000000000307. Read the abstract
Aygun B, Mortier NA, Kesler K, Lockhart A, Schultz WH, Cohen Ar, Alvarez O, Rogers ZR, Kwiatkowski JL, Miller ST, Sylvestre P, Iyer R, Lane PA, Ware RE and the Stroke with Transfusions Changing to Hydroxyurea Trial Investigators. Therapeutic phlebotomy is safe in children with sickle cell anemia and can be effective treatment for transfusional iron overload. Br J Haematol. 2015 Apr;169(2):262-6. doi: 10.1111/bjh.13280. Epub 2015 Jan 22. Read the abstract.
King AA, Rodeghier MJ, Panepinto JA, Strouse JJ, Casella JF, Quinn C, Dowling M…Kwiatkowski JL, Howard TH… DeBaun MR. Silent cerebral infarction, income and grade retention among students with sickle cell. Am J Hematol. 2014 Oct;89(10):E188-92. doi: 10.1002/ajh.23805. Epub 2014 Aug 4. Read the abstract.
DeBaun MR, Gordon M, McKinstry RC, Noetzel MJ…Kwiatkowski JL, King AA, …Casella JF. Controlled trial of transfusions for silent cerebral infarcts in sickle cell anemia. N Engl J Med. 2014 Aug 21;371(8):699-710. doi: 10.1056/NEJMoa1401731. Read the abstract.
Green ST, Martin MB, Haines D, Carson S, Coates T, Oliveros O, Gerstenberger E, Trachtenberg F, Kwiatkowski JL for the Thalassemia Clinical Research Network. Variance of pain prevalence and associated severity during the transfusion cycle of adult thalassemia patients. Br J Haematol. 2014 Sep;166(5):797-800. doi: 10.1111/bjh.12903. Epub 2014 May 8. Read the abstract
Arkuszewski M, Krejza J, Chen R, Ichord R, Kwiatkowski JL, Bilello M, Zimmerman R, Ohene-Frempong K, Melhem ER. Sickle cell anemia: intracranial stenosis and silent cerebral infarcts in children with low risk of stroke. Adv Med Sci. 2014 Mar;59(1):108-13. doi: 10.1016/j.advms.2013.09.001. Epub 2014 Mar 27. Read the abstract.
Kwiatkowski, JL. Thalassemia Minor”and “Beta Thalassemia Major. In: Gulati GL, Filicko-O’Hara J, Krause JR, editors. Case Studies in Hematology and Coagulation. Chicago (IL): American Society for Clinical Pathology Press; 2012.
Kwiatkowski JL. Hemoglobinopathies. In: Lanzkowsky, et al., editors. Manual of Pediatric Hematology and Oncology. 5th ed. London (UK): Elsevier, London; 2011. pp. 200-246.
Kwiatkowski JL, Porter J. Transfusion and Iron Chelation Therapy in Thalassemia and Sickle Cell Disease. In: Steinberg MH, Forget BG, Higgs DR, Weatherall DJ, editors. Disorders of Hemoglobin. 2nd ed. Cambridge University Press; 2009.
Kwiatkowski JL. Iron Deficiency Anemia. In Schwartz, et al., editors. The Five-Minute Pediatric Consult. 5th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2008. pp. 466-7.
Kwiatkowski JL. Microcytic Anemia. In Schwartz, et al., editors. The Five-Minute Pediatric Consult. 5th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2008. pp. 536-7.
Kwiatkowski JL. Aplastic Anemia. In Schwartz, et al., editors. The Five-Minute Pediatric Consult. 5th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2008. pp. 54-5.
Kwiatkowski JL. Thalassemia. In Schwartz, et al., editors. The Five-Minute Pediatric Consult. 5th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2008. pp. 846-7.
Kwiatkowski JL. Section Editor. Clinical Management of Patients with Thalassemia. In: Perspectives on the Treatment of Transfusion-Dependent Hematologic Disorders. Health Science Center for Continuing Medical Education; 2005.
Kwiatkowski JL. Iron Deficiency Anemia. In: The Five-Minute Pediatric Consult. 4th Ed. Schwartz, et al., editors. Philadelphia (PA): Lippincott Williams & Wilkins; 2005. pp. 500-501.
Kwiatkowski JL, Shusterman S. Microcytic Anemia. In: The Five-Minute Pediatric Consult. 4th Ed. Schwartz, et al., editors. Philadelphia (PA): Lippincott Williams & Wilkins; 2005. pp. 62-63.
Kwiatkowski JL, Minturn J. Aplastic Anemia. In: The Five-Minute Pediatric Consult. 4th Ed. Schwartz, et al., editors. Philadelphia (PA): Lippincott Williams & Wilkins; 2005. pp. 134-35.
Bickert B, Kwiatkowski JL. Coagulation Disorders. In: Depiro, et al, editors Pharmacotherapy: A Pathophysiologic Approach. 6th ed. McGraw-Hill; 2005. pp. 1833-1854.
Kwiatkowski JL, Ohene-Frempong K. Stroke in sickle cell disease. In: Okpala I, editor. Practical Management of Haemoglobinopathies. Malden (MA): Blackwell Publishing, Ltd.; 2004. pp. 134-144.
Bickert B, Kwiatkowski JL. Coagulation Disorders. In: Depiro JT, et al, editors. Pharmacotherapy: A Pathophysiologic Approach. 5th ed., McGraw-Hill Companies, Inc.; 2002. pp. 1747-1768.
Kwiatkowski JL. Mentoring Lunch for Women, Underrepresented Minorities, and Early Career Investigators. New York Academy of Sciences, Tenth Cooley’s Anemia Symposium; 2015 Oct 20; Chicago, IL.
Kwiatkowski JL. Current Recommendations for Chelation Therapy in Transfusion-Dependent Thalassemia. New York Academy of Sciences, Tenth Cooley’s Anemia Symposium; 2015 Oct 20; Chicago, IL.
Kwiatkowski JL. The Role of Zinc in Thalassaemia. 8th Annual Advanced Sickle Cell And Thalassaemia Course. Guys and St. Thomas NHS Foundation Trust; 2015 Oct 2; London, UK.
Kwiatkowski JL. Optimizing TCD Screening and Treatment Protocols. 8th Annual Advanced Sickle Cell And Thalassaemia Course. Guys and St. Thomas NHS Foundation Trust; 2015 Oct 2; London, UK.
Kwiatkowski JL. Iron Assessment and Chelation Options. Cooley’s Anemia Foundation Patient-Family Conference; 2015 Jun 21; Chicago, IL.
2001, Ethel Brown Foerderer Fund Fellow
1998, Hematology/Oncology Research Competition Award, Managing Cancer Chemotherapy Toxicities; The Philadelphia-Delaware Valley Association of Hematology/Oncology Fellows
1998, Young Investigator Award; American Society of Clinical Oncology: Role of Schwann Cells in Neuroblastoma Differentiation
1997, Selected participant, American Association for Cancer Research Workshop, Molecular Biology in Clinical Oncology; The Given Institute, Aspen, CO
1992, Charles E. Hamilton Prize
1992, Janet M. Glasgow Memorial Achievement Citation for Scholastic Excellence
1991, Alpha Omega Alpha
1987, Phi Beta Kappa
1985, Phi Eta Sigma
2008-present, Member, Fellowship Committee, University of Pennsylvania
2003-present, Member, Committee for the Protection of Human Subjects, University of Pennsylvania
2006-present, Member, Cooley’s Anemia Foundation Medical Advisory Board
CHOP Clinical Trials Research Affinity Group, Advisory committee member
American Society of Hematology
American Society of Pediatric Hematology/Oncology