Grant T. Liu, MD

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Grant T. Liu, MD, is a pediatric neuro-ophthalmologist at Children's Hospital of Philadelphia (CHOP) and holds the Raymond G. Perelman Endowed Chair in Pediatric Neuro-Ophthalmology. 

Areas of Expertise: Pediatric optic nerve disorders, Pediatric pseudotumor cerebri, Vision testing in children with neurofibromatosis and optic pathway gliomas, Pediatric neuro-ophthalmology
Locations: Main Campus

Phone: 215-590-2791


Dr. Liu is a Pediatric Neuro-ophthalmologist at Children's Hospital of Philadelphia (CHOP) and holds the Raymond G. Perelman Endowed Chair in Pediatric Neuro-Ophthalmology. His practice bridges the fields of ophthalmology and neurology through diagnosis and management of patients with neurological disorders that affect vision and eye movements. Dr. Liu also treats patients with poorly-defined visual symptoms, many of which remain unresolved despite previous ophthalmic and neurologic evaluations.

Dr. Liu evaluates and treats patients with a wide variety of conditions, including double vision, optic neuritis and other optic nerve problems, pupillary abnormalities, unexplained vision loss, visual field defects, migraine and related visual complaints, optic disc swelling, pseudotumor cerebri syndrome, abnormal eye movements (ophthalmoparesis or nystagmus), and intracranial lesions affecting the visual pathway.

Dr. Liu received his medical degree from the Columbia University College of Physicians and Surgeons in 1988. He completed a medical internship at Columbia Presbyterian Hospital from 1988-1989, and a neurology residency at the Harvard-Longwood Neurology Program (Children's Hospital, Brigham and Women's Hospital, Beth Israel, and Brockton-Westbury VA Hospitals in Boston, MA) from 1989-1992. He then completed a neuro-ophthalmology fellowship at the Bascom Palmer Eye Institute in Miami, FL from 1992-1993.

Dr. Liu began practicing neuro-ophthalmology at the University of Pennsylvania and The Children's Hospital of Philadelphia in 1993. He was the first on-site pediatric neuro-ophthalmologist at CHOP where there are now more than 2,000 pediatric neuro-ophthalmic visits per year. Dr. Liu is a member of the University of Pennsylvania's Division of Neuro-ophthalmology in the Departments of Neurology and Ophthalmology. With five full-time faculty members and active clinical and research components, it is one of the largest neuro-ophthalmology groups in the country.

Dr. Liu is also a Professor of Neurology and Ophthalmology at the University Pennsylvania. He is considered an international expert on pediatric neuro-ophthalmic topics such as pediatric pseudotumor cerebri, vision testing in children with neurofibromatosis and optic pathway gliomas, and pediatric optic nerve disorders.

Philadelphia Magazine has named Dr. Liu a "Top Doc" in neuro-ophthalmology every year since 2001. He was awarded one of Penn's 2013-14 Christian R. and Mary F. Lindback Awards for Distinguished Teaching.

Dr. Liu co-authored the textbook, Neuro-ophthalmology: Diagnosis and Management (2nd edition, Elsevier, 2010); a reviewer in the New England Journal of Medicine called the first edition "probably the best-illustrated, most comprehensive single-volume textbook on neuro-ophthalmology available today." The release of the third edition is planned for Fall 2017.

Education and Training

Medical School

MD - Columbia University College of Physicians and Surgeons, New York, NY


Columbia-Presbyterian Hospital, New York, NY


Harvard-Longwood Neurology Program at Children's Hospital, Boston, MA


Bascom Palmer Eye Institute, Miami, FL

Board Certification

American Board of Psychiatry and Neurology

Titles and Academic Titles


Raymond G. Perelman Endowed Chair in Pediatric Neuro-Ophthalmology

Professor of Neurology, Perelman School of Medicine at the University of Pennsylvania

Conditions Treated

Departments and Services




Jivraj I, SJ, Liu GT. Characteristics and long-term follow-up of isolated vertical nystagmus in infancy. J Pediatr Ophthalmol Strabismus. 2018;55(3):159-163.


de Blank PMK, Fisher MJ, Liu GT, Gutmann DH, Listernick R, Ferner RE, Avery RA. Optic pathway gliomas in neurofibromatosis type 1: an update: surveillance, treatment indications, and biomarkers of vision. J Neuroophthalmol. 2017;37(Suppl 1):S23-S32.

Swanson JW, Aleman TS, Xu W, Ying GS, Pan W, Liu GT, Lang SS, Heuer GG, Storm PB, Bartlett SP, Katowitz WR, Taylor JA. Evaluation of optical coherence tomography to detect elevated intracranial pressure in children. JAMA Ophthalmol. 2017;135(4):320-328.

Sheldon CA, Paley GL, Beres SJ, McCormack SE, Liu GT. Pediatric pseudotumor cerebri syndrome: diagnosis, classification, and underlying pathophysiology. Semin Pediatr Neurol. 2017;24(2):110-115.


Liu AM, Liu JG, Liu GW, Liu GT. "Alice in wonderland" syndrome: presenting and follow-up characteristics. Pediatr Neurol. 2014 Sep;51(3):317-20.

Bisker ER, McClelland CM, Brown LW, Liu GT. The long-term outcomes of ocular tics in a pediatric neuro-ophthalmology practice. J AAPOS. 2014 Feb;18(1):31-5.


Fisher MJ, Avery R, Allen J, Ardern-Holmes A, Bilaniuk L, Ferner R, Gutmann D, Listernick R, Martin S, Ullrich N, Liu GT. Functional outcomes for neurofibromatosis type 1-associated optic pathway glioma clinical trials. Neurology. 2013 Nov 19;81(21 Suppl 1):S15-24.

Friedman DI, Liu GT, Digre KB. Revised diagnostic criteria for the pseudotumor cerebri syndrome in adults and children. Neurology. 2013 Sep 24;81(13):1159-65.

Liu GT, Katowitz JA, Rorke-Adams LB, Fisher MJ.  Optic pathway gliomas: neoplasms, not hamartomas. JAMA Ophthalmol. 2013 May;131(5):646-50.


Fisher MJ, Loguidice M, Liu GT, et al.  Visual outcomes in children with neurofibromatosis type 1-associated optic pathway glioma following chemotherapy: a multicenter retrospective analysis. Neuro Oncol. 2012 Jun;14(6):790-7.