Laura M. Mercer-Rosa, MD, MSCE
About Laura M. Mercer-Rosa, MD, MSCE
As a pediatric cardiologist, Laura Mercer-Rosa, MD, MSCE, focuses on providing the best possible care for her own patients at CHOP. As a clinical epidemiologist, she expands her scope, studying the outcomes of treatments for hundreds of children at hospitals far and wide.
In both cases, it’s all about making lives better for children with heart disease.
Dr. Mercer is interested in congenital heart disease, particularly tetralogy of Fallot, a complex condition involving four distinct defects of the heart and nearby blood vessels.
“Tetralogy of Fallot is a disease that requires surgery and lifelong follow up,” says Dr. Mercer-Rosa,“ and I appreciate being able to see how patients recover from surgery and to have the opportunity to follow them as they grow up.”
Cases of tetralogy of Fallot vary a great deal in severity and in configuration, and CHOP’s Cardiac Center is adept at diagnosing and treating each case individually. Dr. Mercer-Rosa’s work as an echocardiographer produces images that allow her and her colleagues to discern the specific contours of each patient’s heart.
“I am happy to see that we are personalizing the care for children with congenital heart defects,” says Dr. Mercer-Rosa. “There is really no one-type-fits-all surgical repair, and we are understanding more and more the differences that exist from patient to patient. The better we understand these differences, the more optimal care we will be able to provide.”
Dr. Mercer-Rosa is an active researcher, with scores of publications. A particular focus is outcomes in tetralogy of Fallot, both early and late. She also has an active research interest in right ventricular function in different disease processes.
As patients or research subjects, the kids come first for Dr. Mercer-Rosa. “I want families to know (and feel) that we care deeply about them and that we strive to provide them with the best possible care,” she says.
Titles
Attending Cardiologist
Associate Professor in Pediatrics, Perelman School of Medicine at the University of Pennsylvania
Certifications
Pediatric Cardiology – American Board of Pediatrics
Pediatrics – American Board of Pediatrics
Awards and Honors
2019, Women in White Coats Heroes Award, Women in White Coats Project
2016, Faculty Honor Roll, Children's Hospital of Philadelphia
2006, Ann Newman Award, Division of Cardiology, The Children's Hospital of Philadelphia
2005, Arturo Avally Award for the Resident of the Year, Miami Children's Hospital
2005, Agostin Castellanos Award for the Resident of the Year, Miami Children's Hospital
2003, Best Intern Award from the Emergency Medicine Division at Miami Children's Hospital
Leadership and Memberships
Memberships in Professional Organizations
2005-present, American Society of Echocardiography
- 2017-present, Task Force for Pediatric Transesophageal Guidelines Writing Committee
2005-present, American Heart Association
Editorial and Academic Positions
Editorial Positions
2019-present, International Editorial Board, Arquivos Brasileiros de Cardiologia: Imagem Cardiovascular
2019-present, Reviewer, Acta Anaesthesiologica Scandinavica
2018-present, Reviewer, Perfusion
2018-present, External Reviewer, Appropriate Use Criteria (AUC) manuscript on Multimodality Imaging During the Follow-Up Care of Patients with Congenital Heart Disease, Journal of the American College of Cardiology
2017-present, Reviewer, Circulation
2017-present, Reviewer, Circulation Cardiovascular Imaging
2015-present, Reviewer, American Heart Journal
2014-present, Reviewer, European Heart Journal Cardiovascular Imaging
2013-present, Reviewer, Journal for Thoracic and Cardiovascular Surgery
2013-present, Reviewer, Journal of the American Society of Echocardiography
Academic and Institutional Committees
2020-present, Additional Ventures Innovation Fund Grant Proposal, Children's Hospital of Philadelphia Cardiac Center and Research Institute
2020-present, Additional Ventures Innovation Fund proposal, Children's Hospital of Philadelphia Research Institute
2020-present, Reviewer, Junior Investigator Pilot Grant Program, University of Pennsylvania Institute for Translational Therapeutics, Center for Human Phenomic Science, 2020 Grant Cycle
2019-present, Reviewer, Pennsylvania Pediatric Medical Device Consortium Grant
2019-present, Search Committee, Cardiac Center Research Director
2019-present, Cardiac Center Faculty Scientist Search Committee
2019-present, Assistant Chair, Scholarship Oversight Committee, Division of Cardiology
2017-present, Assistant Program Director, T32 training program, Division of Cardiology
2017-present, Steering Committee, Cardiology T32 program
2017-present, Scholarship Oversight Committee, Division of Neonatology
2016-present, Elizabeth Blackwell Society, University of Pennsylvania
2016-present, Cardiac Center Strategic Plan Steering Committee
2016-present, Cardiology Fellowship Program Selection Committee
2016-present, Advisory Committee, Cardiac Center Clinical Research Core
2016-present, Cardiac Center Strategic Plan Research Working Group
2016-present, Scholarship Oversight Committee, Division of Pediatric Rheumatology, University of Pennsylvania Perelman School of Medicine
2016-present, ACGME Fellowship Committee, Division of Pediatric Cardiology
2016-present, T32 Internal Advisory Committee
2015-present, Reviewer, The Cardiac Center Grant Program
2015-present, Reviewer, The Center for Pediatric Clinical Effectiveness Pilot Grant
2015-present, Alliance for Minority Physicians, University of Pennsylvania
2014-present, Cardiac Center Scientific Committee, Division of Cardiology
2013-present, Interview Committee, Perelman School of Medicine, University of Pennsylvania Medical School
2013-present, Scholarship Oversight Committee, Division of Pediatric Cardiology
Education & training
Graduate Degree
MSCE - University of Pennsylvania, Philadelphia, PA
Medical Degree
MD - Universidade Federal do Parana, Brazil
Residency
Pediatrics - Hospital de Clinicas, Curitiba, Brazil
Pediatrics - Miami Children's Hospital, Miami, FL
Fellowship
Pediatric Cardiology - Instituto do Coracao, Sao Paulo, Brazil
Pediatric Cardiology - The Children's Hospital of Philadelphia, Philadelphia, PA
Echocardiography - The Children's Hospital of Philadelphia, Philadelphia, PA
Publications
Publications
2021
Edelson JB, Rossano JW, Griffis H, Quarshie WO, Ravishankar C, O'Connor MJ, Mascio CE, Mercer-Rosa L, Glatz AC, Lin KY.: Resource Use and Outcomes of Pediatric Congenital Heart Disease Admissions: 2003 to 2016. J Am Heart Assoc 10(4): e018286, Feb 16 2021.
Favilla E, Faerber JA, Hampton LE, Tam V, DeCost G, Ravishankar C, Gaynor JW, Burnham A, Licht DJ, Mercer-Rosa L. : Early Evaluation and the Effect of Socioeconomic Factors on Neurodevelopment in Infants with Tetralogy of Fallot. Pediatr Cardiol Feb 2021 Notes: Epub ahead of print.
Himebauch AS, Wong W, Wang Y, McGowan FX, Berg RA, Mascio CE, Kilbaugh TJ, Lin KY, Goldfarb SB, Kawut SM, Mercer-Rosa L, Yehya N.: Preoperative echocardiographic parameters predict primary graft dysfunction following pediatric lung transplantation. Pediatr Transplant 25(2): e13858, Mar 2021.
2020
Chang, J. C., Xiao, R., Meyers, K. E., Mercer-Rosa, L., Natarajan, S. S., Weiss, P. F., Knight, A. M. : Nocturnal blood pressure dipping as a marker of endothelial function and subclinical atherosclerosis in pediatric-onset systemic lupus erythematosus. Arthritis research & therapy 22(1): 129, June 2020.
Lianza AC, Rodrigues ACT, Mercer-Rosa L, Vieira MLC, de Oliveira WAA, AfonsoTR, Nomura CH, da Silva JP, da Silva LDF, Szarf G, Tavares GMP, Fischer CH, MorhySS. : Right Ventricular Systolic Function After the Cone Procedure for Ebstein'sAnomaly: Comparison Between Echocardiography and Cardiac Magnetic Resonance. Pediatr Cardiol. 41(5): 985-995, Jun 2020.
Wu KY, Jensen EA, White AM, Wang Y, Biko DM, Nilan K, Fraga MV, Mercer-Rosa L,Zhang H, Kirpalani H: Characterization of Disease Phenotype in Very Preterm Infants with Severe Bronchopulmonary Dysplasia. Am J Respir Crit Care Med 201(11): 1398-1406, Jun 1 2020.
Bhatt SM, O'Byrne M, McBride M, Paridon SM, Goldmuntz E, Mercer-Rosa L: Chronotropic Response and Pulmonary Function are Associated with Exercise Performance in Children and Adolescents with Repaired Tetralogy of Fallot Independent of Cardiac Function. Congenital Heart Disease 15(2): 101-115, July 2020.
Joyce C. Chang, Rui Xiao, Andrea M. Knight, Stephen E. Kimmel, Laura Mercer-Rosa,Pamela F. Weiss: A Population-based Study of Risk Factors for Heart Failure in Pediatric and Adult-onsetSystemic Lupus Erythematosus. Seminars in Arthritis and Rheumatism 50(4): 527-533, Aug 2020.
O'Byrne ML, DeCost G, Katcoff H, Savla JJ, Chang J, Goldmuntz E, Groeneveld PW, Rossano JW, Faerber JA, Mercer-Rosa L.: Resource Utilization in the First 2 Years Following Operative Correction for Tetralogy of Fallot: Study Using Data From the Optum's De-Identified Clinformatics Data Mart Insurance Claims Database. J Am Heart Assoc 9(15): e016581, Aug 4 2020.
Campbell MJ, Quartermain MD, Cohen MS, Faerber J, Okunowo O, Wang Y, Capone V, DiFrancesco J, Mercer-Rosa L, Goldberg DJ.: Longitudinal changes in echocardiographic measures of ventricular function after Fontan operation. Echocardiography 37: 1443-1448, Sep 2020.
D'Souza R, Wang Y, Calderon-Anyosa RJC, Montero AE, Banerjee MM, Ekhomu O,Matsubara D, Mercer-Rosa L, Agger P, Sato T, Banerjee A. : Decreased right ventricular longitudinal strain in children with hypoplastic left heart syndrome during staged repair and follow-up: does it have implications in clinically stable patients? Int J Cardiovasc Imaging. 36(9): 1667-1677, Sep 2020.
Ho DY, Katcoff H, Griffis HM, Mercer-Rosa L, Fuller SM, Cohen MS. : Left Valvar Morphology is Associated with Late Regurgitation in Atrioventricular CanalDefect. Ann Thorac Surg 110(3): 969-978, Sep 2020.
Avitabile CM, Wang Y, Zhang X, Griffis H, Saavedra S, Adams S, Herkert L, Frank DB, Quartermain MD, Rintoul NE, Hedrick HL, Mercer-Rosa L.: Right Ventricular Strain, Brain Natriuretic Peptide, and Mortality in Congenital Diaphragmatic Hernia. Ann Am Thorac Soc 17: 1431-1439, Nov 2020.
Chang JC, Wang Y, Xiao R, Fedec A, Meyers KE, Tinker C, Natarajan SS, Knight AM, Weiss PF, Mercer-Rosa L.: Echocardiographic strain analysis reflects impaired ventricular function in youth with pediatric-onset systemic lupus erythematosus. Echocardiography 37: 2082-2090, Dec 2020.
2019
Bhatt SM, Elci OU, Wang Y, Goldmuntz E, McBride M, Paridon S, Mercer-Rosa L.: Determinants of exercise performance in children and adolescents with repaired tetralogy of Fallot using stress echocardiography. Pediatr Cardiol 40(1): 71-78, Jan 2019.
Bhatt SM, Wang Y, Elci OU, Goldmuntz E, McBride M, Paridon S, Mercer-Rosa L.: Right ventricular contractile reserve is impaired in children and adolescents with repaired tetralogy of Fallot; an exercise strain imaging study. J Am Soc Echocardiogr 32(1): 135-144, Jan 2019.
Mercer-Rosa L, Zhang X, Tanel RE, Rychik J, Fogel MA, Paridon SM, Goldmuntz E.: Perioperative factors influence the long-term outcomes of children and adolescents with repaired tetralogy of Fallot. Pediatr Cardiol 40(1): 71-78, Jan 2019.
Frommelt P, Hu C, Trachtenberg F, Baffa J, Boruta J, Chowdhury S, Cnota J, Dragulescu A, Levine J, Lu J, Mercer-Rosa L, Miller T, Shah A, Stapleton G, Stelter J, Slesnick T, Wong P, Newburger J (For the PHN Investigators) : Impact of Initial Shunt Type on Echocardiographic Indices in Children After Single Right Ventricle Palliations. Circ Cardiovasc Imaging 12(2): e007865, Feb 2019.
White BR, Katcoff H, Faerber JA, Lin KY, Rossano JW, Mercer-Rosa L, O'Connor MJ: Echocardiographic Assessment of Right Ventricular Function in Clinically Well Pediatric Heart Transplant Patients with Comparison to Normal Controls. J Am Soc Echocardiogr 4(32): 537-544, Apr 2019.
Avitabile CM, Ansems S, Wang Y, Fraga MV, Kirpalani HM, Zhang H. Mercer-Rosa L. Jensen EA : Accuracy of brain natriuretic peptide for diagnosing pulmonary hypertension in severe bronchopulmonary dysplasia. Neonatology 16(1): 1-7, May 2019.
Gardner MM, Mercer-Rosa L, Faerber J, DiLorenzo MP, Bates KA, Stagg A, Natarajan SS, Szwast A, Fuller S, Mascio CE, Fleck D, Torowicz DL, Giglia TM, Rome JJ, Ravishankar C: Association of a Home Monitoring Program with Interstage and Stage 2 Outcomes. J Am Heart Assoc. 8(10): e010783, May 2019.
Nguyen AV, Lasso A, Nam HH, Faerber J, Aly AH, Pouch AM, Scanlan AB, McGowan FX, Mercer-Rosa L, Cohen MS, Simpson J, Fichtinger G, Jolley MA.: Dynamic Three-Dimensional Geometry of the Tricuspid Valve Annulus in Hypoplastic Left Heart Syndrome with a Fontan Circulation. J Am Soc Echocardiogr 32(5): 655-666, May 2019.
Chang JC, White BR, Elias MD, Xiao R, Knight A, Weiss PA, Mercer-Rosa L: Echocardiographic Assessment of Diastolic Function in Children with Incident Systemic Lupus Erythematosus. Pediatric Cardiology 40(5): 1017-1025, Jun 2019.
Narayan HK, Putt ME, Kosaraju N, Paz A, Bhatt S, Plappert T, Mercer-Rosa L, Armenian SH, Desai AV, Womer RB, Ky B.: Dexrazoxane preferentially mitigates doxorubicin cardiotoxicity in female children with sarcoma. Open Heart 6(1): e001025, Jun 2019.
Ansems S, Kirpalani H, Mercer-Rosa L, Wang Y, Hopper R, Fraga MV, Jensen E: Patent Ductus Arteriosus and the Effects of its late Closure in Preterm Infants With Severe Bronchopulmonary Dysplasia. Neonatology Page: doi: 10.1159, Jul 2019 Notes: Epub ahead of print.
Gaulton JS, Mercer-Rosa LM, Glatz AC, Jensen EA, Capone V, Scott C, Appel SM, Stoller JZ, Fraga MV.: Relationship between pulmonary artery acceleration time and pulmonary artery pressures in infants. Echocardiography 36(8): 1524-1531, Aug 2019.
Thanh Hoang; Paulo Henrique Manso; Sharon Edman; Laura Mercer-Rosa; Laura Mitchell; Anshuman Sewda; Michael Swartz; Mark Fogel; A.J. Agopian; Elizabeth Goldmuntz: Genetic Variants of HIF1α are associated with Right Ventricular Fibrotic Load in Repaired Tetralogy of Fallot Patients J Cardiovasc Magn Reson 21(1): 51, Aug 2019.
Savla JJ, Faerber JA, Huang YV, Zaoutis T, Goldmuntz E, Kawut SM, Mercer-Rosa L.: 2-Year Outcomes After Complete or Staged Procedure for Tetralogy of Fallot in Neonates. J Am Coll Cardiol 74(12): 1570-1579, Sep 24 2019.
Bailey J, Elci OU, Mascio CE, Mercer-Rosa L, Goldmuntz E: Staged versus Complete Repair in the Symptomatic Neonate with Tetralogy of Fallot. Annals of Thoracic Surgery November 2019 Notes: ePub ahead of print.
Butto A, Mercer-Rosa L, Teng C, Daymont C, Edelson J, Faerber J, Mejia E,Ravishankar C, Cohen MS: Longitudinal growth in patients with single ventriclecardiac disease receiving tube-assisted feeds. Congenit Heart Dis 14(6): 1058-1065, Nov 2019.
Morgan RW, Topjian AA, Wang Y, Atkin NJ, Kilbaugh TJ, McGowan FX, Berg RA, Mercer-Rosa L, Sutton RM, Himebauch AS.: Prevalence and Outcomes of Pediatric In-Hospital Cardiac Arrest Associated With Pulmonary Hypertension. Pediatr Crit Care Med Page: doi: 10.1097, Nov 5 2019 Notes: Epub ahead of print.
Allen KY, Jones S, Jackson T, DeCost G, Stephens P, Hanna BD, Cohen MS, Smith-Whitley K, Mercer-Rosa L, Natarajan SS.: Echocardiographic Screening of Cardiovascular Status in Pediatric Sickle Cell Disease. Pediatr Cardiol(8), 1670-1678, Dec 2019.
Himebauch AS, Yehya N, Wang Y, McGowan FX, Mercer-Rosa L: New or Persistent Right Ventricular Systolic Dysfunction is Associated with Worse Outcomes in Pediatric Acute Respiratory Distress Syndrome. Pediatr Crit Care Med. Dec 2019 Notes: Epub ahead of print.
2018
Hopper RK, Wang Y, DeMatteo V, Santo A, Kawut SM, Elci OU, Hanna BD, Mercer-Rosa L.: Right ventricular function mirrors clinical improvement with use of prostacyclin analogues in pediatric pulmonary hypertension. Pulm Circ 8(2): doi: 10.1177, Apr-Jun 2018.
DiLorenzo MP, Goldmuntz E, Nicolson SC, Fogel MA, Mercer-Rosa L.: Early postoperative remodelling following repair of tetralogy of Fallot utilising unsedated cardiac magnetic resonance: a pilot study. Cardiol Young 28(5): 697-701, May 2018.
Mercer-Rosa L, Elci OU, DeCost G, Woyciechowski M, Edman SM, Ravishankar C, Mascio CE, Kawut SM, Goldmuntz E.: Predictors of length of hospital stay after complete repair for tetralogy of Fallot: a prospective cohort study. J Am Heart Assoc 7(11): doi: 10.1161, May 2018.
Nawaytou HM, Mercer-Rosa L, Channing A, Cohen MS: Intraoperative transesophageal echocardiographic predictors of recurrent left ventricular outflow tract obstruction in children undergoing subaortic stenosis resection. Echocardiography 35(5): 678-684, May 2018.
Mercer-Rosa L, Elci OU, Pinto NM, Tanel RE, Goldmuntz E.: 22q11.2 deletion status and perioperative outcomes for tetralogy of Fallot with pulmonary atresia and multiple aortopulmonary collateral vessels. Pediatr Cardiol 39(5): 906-910, Jun 2018.
Chang JC, Knight AM, Xiao R, Mercer-Rosa L, Weiss PF: Use of echocardiography at diagnosis and detection of acute cardiac disease in youth with systemic lupus erythematosus. Lupus 27(8): 1348-1357, Jul 2018.
DiLorenzo MP, Elci OU, Wang Y, Banerjee A, Sato T, Ky B, Goldmuntz E, Mercer-Rosa L.: Longitudinal changes in right ventricular function in tetralogy of Fallot in the initial years after surgical repair. J Am Soc Echocardiogr 31(7): 816-821, Jul 2018.
DiLorenzo MP, Santo A, Faerber JA, Rome JJ, Zhang H, Mercer-Rosa L, Hopper RK: Pulmonary vein stenosis: outcomes in children with congenital heart disease and prematurity. Semin Thorac Cardiovasc Surg Page: doi: 10.1053, Sept 2018.
DiLorenzo M, Hwang WT, Goldmuntz E, Ky B, Mercer-Rosa L.: Diastolic dysfunction in tetralogy of Fallot: comparison of echocardiography with catheterization. Echocardiography 35(10): 1641-1648, Oct 2018.
Edelson JB, Rossano JW, Griffis H, Dai D, Faeber J, Ravishankar C, Mascio CE, Mercer-Rosa LM, Glatz AC, Lin KY.: Emergency department visits by children with congenital heart disease. J Am Coll Cardiol. 72(15): 1817-1825, Oct 2018.
Mercer-Rosa L, Fogel MA, Paridon SM, Rychik J, Yang W, Goldmuntz E: Revisiting the end-diastolic forward flow (restrictive physiology) in tetralogy of Fallot: an exercise, echocardiographic, and magnetic resonance study. JACC Cardiovasc Imaging 11(10): 1547-1548, Oct 2018.
Chang JC, Xiao R, Mercer-Rosa L, Knight AM, Weiss PF: Child-onset systemic lupus erythematosus is associated with a higher incidence of myopericardia manifestations compared to adult-onset disease. Lupus 27(13): 2146-2154, Nov 2018 Notes: Epub ahead of print.
Himebauch AS, Yehya N, Wang Y, Conlon T, Kilbaugh TJ, McGowan FX, Mercer-Rosa L.: Early right ventricular systolic dysfunction and pulmonary hypertension are associated with worse outcomes in pediatric acute respiratory distress syndrome. Crit Care Med 46(11): e1055-e1062, Nov 2018.
Savla JJ, Fisher BT, Faerber JA, Huang YV, Mercer-Rosa L.: Complete versus staged repair for neonates with Tetralogy of Fallot: establishment and validation of a cohort of 2235 patients using detailed surgery sequence review of health care administrative data. Med Care 56(11): e76-e82, Nov 2018.
2017
Anwar S, Harris MA, Whitehead KK, Keller MS, Goldmuntz E, Fogel MA, Mercer-Rosa L: The impact of the right ventricular outflow tract patch on right ventricular strain in tetralogy of Fallot. A comparison with valvar pulmonary stenosis utilizing cardiac magnetic resonance. Pediatr Cardiol 38(3): 617-623, Mar 2017.
Bhat M, Mercer-Rosa L, Fogel MA, Harris MA, Paridon S, McBride MG, Shults J, Zhang X, Goldmuntz E: Longitudinal changes in adolescents with TOF: implications for care. Eur Heart J Cardiovasc Imaging 18(3): 356-363, Mar 2017 Notes: Co-first author.
Goldmuntz E, Cassedy A, Mercer-Rosa L, Fogel MA, Paridon SM, Marino BS.: Exercise performance and 22q11.2 deletion status affect qualityof life in Tetralogy of Fallot. Journal of Pediatrics 189: 162-168, October 2017.
Bhatt SM, Goldmuntz E, Cassedy A, Marino BS, Mercer-Rosa L: Quality of life is diminished in patients with tetralogy of Fallot with mild residual disease: a comparison of tetralogy of Fallot and isolated valvar pulmonary stenosis. Pediatr Cardiol 38(8): 1645-1653, December 2017.
2016
Patel JK, Loomes KM, Goldberg DJ, Mercer-Rosa L, Dodds K, Rychik J: Early impact of Fontan operation on enteric protein loss. Ann Thorac Surg 101(3): 1025, Mar 2016.
Friedberg MK, Margossian R, Lu M, Mercer-Rosa L, Henderson HT, Nutting A, Friedman K, Molina KM, Altmann K, Canter C, Sleeper LA, Colan SD: Systolic-diastolic functional coupling in healthy children and in those with dilated cardiomyopathy. J Appl Physiol 120(11): 1301-18, June 2016.
Bhat M, Goldmuntz E, Fogel MA, Rychik J, Mercer-Rosa L: Longitudinal validation of the diastolic to systolic time-velocity integral ratio as a doppler-derived measure of pulmonary regurgitation in patients with repaired tetralogy of Fallot. Pediatric Cardiology 38(2): 240-246, Nov 2016.
Goldberg DJ, French B4, Szwast AL, McBride MG, Paridon SM, Rychik J, Mercer-Rosa L.: Tricuspid annular plane systolic excursion correlates with exercise capacity in a cohort of patients with hypoplastic left heart syndrome after Fontan operation. Echocardiography 33(12): 1897-1902, Dec 2016.
2015
O'Byrne ML, Glatz AC, Mercer-Rosa L, Gillespie MJ, Dori Y, Goldmuntz E, Kawut S, Rome JJ: Trends in pulmonary valve replacement in children and adults with tetralogy of Fallot. Am J Cardiol 115(1): 118-24, Jan 2015.
Mercer-Rosa L, Paridon SM, Fogel MA, Rychik J, Tanel RE, Zhao H, Zhang X, Yang W, Shults J, Goldmuntz E: 22q11.2 Deletion status and disease burden in children and adolescents with tetralogy of Fallot. Circ: Cardiovas Genet 8(1): 74-81, Feb 2015.
Avitabile CM, Mercer-Rosa L, Ravishankar C, Rome JJ, Gaynor JW, Spray TL, Cohen MS: Experience with biventricular intervention for neonates with mitral valve abnormalities in the setting of critical left-side heart obstruction. Ann Thorac Surg 99(3): 877-83, Mar 2015.
Mercer-Rosa L, Ingall E, Zhang X, McBride M, Kawut S, Fogel M, Paridon S, Goldmuntz E: The impact of pulmonary insufficiency on the right ventricle: a comparison of isolated valvar pulmonary stenosis and tetralogy of Fallot. Pediatr Cardiol 36(4): 796-801, Apr 2015.
Shariat M, Mertens L, Seed M, Grosse-Wortmann L, Golding F, Mercer-Rosa L, Harris M, Whitehead KK, Li C, Fogel MA, Yoo S : Utility of feed-and-sleep cardiovascular magnetic resonance in young infants with complex cardiovascular disease. Pediatr Cardiol 36(4): 809-12, Apr 2015.
2014
O'Byrne ML, Mercer-Rosa L, Zhao H, Zhang X, Yang W, Tanel RE, Marino BS, Cassedy A, Fogel MA, Rychik J, Paridon S, Goldmuntz E: Morbidity in children and adolescents after surgical correction of interrupted aortic arch. Pediatr Cardiol 35(3): 386-92, Mar 2014.
Avitabile CM, Whitehead K, Fogel M, Mercer-Rosa L: Tricuspid annular plane systolic excursion does not correlate with right ventricular ejection fraction in patients with hypoplastic left heart syndrome after Fontan palliation. Pediatr Cardiol 35(7): 1253-8, Oct 2014.
O'Byrne ML, Yang W, Mercer-Rosa L, Parnell AS, Oster ME, Levenbrown Y, Tanel RE, Goldmuntz E: 22q11.2 Deletion syndrome is associated with increased perioperative events and more complicated postoperative course in infants undergoing infant operative correction of truncus arteriosus communis or interrupted aortic arch. J Thorac Cardiovasc Surg 148(4): 1597-605, Oct 2014.
2013
Pediatric Cardiac Genomics Consortium, Gelb B, Brueckner M, Chung W, Goldmuntz E, Kaltman J, Kaski JP, Kim R, Kline J, Mercer-Rosa L, Porter G, Roberts A, Rosenberg E, Seiden H, Seidman C, Sleeper L, Tennstedt S, Kaltman J, Schramm C, Burns K, Pearson G, Rosenberg E: The congenital heart disease genetic network study: rationale, design, and early results. Circ Res 112(4): 698-706, Feb 2013.
O'Byrne ML, Mercer-Rosa L, Ingall E, McBride MG, Paridon S, Goldmuntz E: Habitual exercise correlates with exercise performance in patients with conotruncal abnormalities. Pediatr Cardiol 34(4): 853-60, Apr 2013.
O'Byrne ML, Mercer-Rosa L, Zhao H, Zhang X, Yang W, Cassedy A, Fogel MA, Rychik J, Tanel RE, Marino BS, Paridon S, Goldmuntz E: Morbidity in children and adolescents after surgical correction of truncus ateriosus communis. Am Heart J 166(3): 512-8, Sep 2013.
Mercer-Rosa L, Pinto N, Yang W, Tanel R, Goldmuntz E: 22q11.2 Deletion syndrome is associated with perioperative outcome in tetralogy of Fallot. J Thorac Cardiovasc Surg 146(4): 868-73, Oct 2013.
Mercer-Rosa L, Parnell A, Forfia PR, Yang W, Goldmuntz E, Kawut SM: Tricuspid annular plane systolic excursion in the assessment of right ventricular function in children and adolescents after repair of tetralogy of Fallot. J Am Soc Echocardiogr 26(11): 1322-9, Nov 2013.
2012
Mercer-Rosa L, Yang W, Kutty S, Rychik J, Fogel M, Goldmuntz E: Quantifying pulmonary regurgitation and right ventricular function in surgically repaired tetralogy of Fallot: a comparative analysis of echocardiography and magnetic resonance imaging. Circ Cardiovasc Imaging 5(5): 637-43, Sep 2012.
2011
Vetter VL, Dugan N, Guo R, Mercer-Rosa L, Gleason M, Cohen M, Vogel RL and Iyer R: A pilot study of the feasibility of heart screening for sudden cardiac arrest in healthy children. Am Heart J 161(5): 1000-1006, May 2011.
2006
Lopez L, Mercer-Rosa L, Zahn EM, Altman NR, Dubois R, Burke RP: The "hinge-twist" technique for anomalous origin of the left coronary artery. Ann Thorac Surg 82(2): e19-21, Aug 2006.
Mercer-Rosa L, Fedec A, Gruber P, Seliem M: Cor triatriatum sinister with and without left ventricular inflow obstruction: visualization of the entire supravalvular membrane by real-time three-dimensional echocardiography. Impact on clinical management of individual patient. Congenit Heart Dis 1(6): 335-9, Nov 2006.
Mercer-Rosa L, Seliem MA, Fedec A, Rome J, Rychik J, Gaynor JW: Illustration of the additional value of real-time 3-dimensional echocardiography to conventional transthoracic and transesophageal 2-dimensional echocardiography in imaging muscular ventricular septal defects: does this have any impact on individual patient treatment. J Am Soc Echocardiogr 19(12): 1511-9, Dec 2006.
Abstracts (includes Posters and Scientific Presentations)
2019
Ekhomu E, Wang Y, Bhatt S, Banerjee S, Mercer-Rosa L: Changes in Right Atrial Function after Initial Surgical Repair for Tetralogy of Fallot. 22nd Annual Update on Pediatric and Congenital Cardiovascular Disease, Huntington Beach, CA Feb 2019 Notes: Poster presentation.
Yuli Y. Kim, Jennifer Faerber, Katherine Awh, Stephanie Fuller, Lacey Gleason, Emily Ruckdeschel, Courtney Scott, Morgan Venuti, Xuemei Zhang, Rosaline Zhang, Laura Mercer-Rosa: Impact of Age on Poor Reverse Right Ventricular Remodeling after Pulmonary Valve Replacement in Tetralogy of Fallot Scientific Sessions of the American Society of Echocardiography, Portland, Oregon June 2019 Notes: Rapid Fire and Poster Presentation.
Lectures by Invitation
2021
Mercer-Rosa L. "Challenging Imaging in 2021 in Late-Postoperative of Congenital Heart Disease" _Tetralogy of Fallot", International Symposium of Cardiovascular Imaging (DIC 2021), An Imaging Tour Around the World, Brazil, Digital Format Meeting. Mar 2021.
Mercer-Rosa L. "Intraop TOF decisions: There Is Residual_Pulmonic Stenosis - Leave It or Fix It?", Cardiology 2020, 24th Annual Update on Pediatric and Congenital Cardiovascular Disease, Digital Format Meeting. Feb 2021.
2020
Mercer-Rosa L. "Avaliação da Função do Ventrículo Único Através da Multimodalidade de Imagem", 26th Congresso Brasileiro de Cardiologia e Cirurgia Cardiovascular Pediátrica (lecture in Portuguese), Digital Format Meeting, Brazil. Dec 2020.
Mercer-Rosa L. "My Life and Career as a Pediatric Cardiologist", lecture to Solebury School STEM Week, New Hope, PA. Oct 2020.
Mercer-Rosa L. Speaker, "Casos Inusitados em Cardiologia Pediátrica: do Diagnóstico `a Intervenção" (Surprising Cases in Pediatric Cardiology: from Diagnosis to Intervention"), Webinar at the Brazilian Department of Pediatric Cardiology of the Brazilian Society of Cardiology (Departamento de Cardiopatias Congênitas e Cardiologia Pediátrica), São Paulo, Brazil, September 10, 2020. Sept 2020.
Mercer-Rosa L. "Imaging Late After Tetralogy of Fallot Repair", Featured Topics in Tetralogy of Fallot, Joint Meeting Congenital Heart Academy and Saudi Heart Association (Webinar). July 2020.
Mercer-Rosa L. "Avaliação por Imagem da Função e das Complicações dos Pacientes Pós Operatório de Fontan" (Imaging Assessment of Function and Complications of Patients after the Fontan Operation), Criança 2020, Curitiba, Brazil. Postponed due to COVID-19 pandemic. May 2020.
Mercer-Rosa L. "Importância do Ecocardiograma em pós-Operatório Imediato de Fontan e o que Valorizar" (Role of Echocardiography in the Early Post-Operative Assessment of the Fontan Operation and What to Assess), Criança 2020, Curitiba, Brazil. Postponed due to COVID-19 pandemic. May 2020.
Mercer-Rosa L. "Sistema Linfático em Pós-Operatório de Fontan - Em que Ponto Estamos?" (The Lymphatic System After the Fontan Operation- Where are we?), Criança 2020, Curitiba, Brazil. Postponed due to COVID-19 pandemic. May 2020.
Mercer-Rosa L. "Avaliação Ecocardiográfica do Coração Univentricular Não Operado" (Echocardiographic Assessment of the Unoperated Single Ventricle Heart), Criança 2020, Curitiba, Brazil. Postponed due to COVID-19 pandemic. May 2020.
Mercer-Rosa L. "Tricuspid Valve Anomalies: Echocardiography", 5th North American Echocardiography Course on Congenital Heart Disease, Stanford University, Palo Alto, CA, Course cancelled due to COVID-19 pandemic. Apr 2020.
Mercer-Rosa L. "RV Function", 5th North American Echocardiography Course on Congenital Heart Disease, Stanford University, Palo Alto, CA, Course cancelled due to COVID-19 pandemic. Apr 2020.
Mercer-Rosa L. "Tricuspid Valve Anomalies: Echocardiography", 5th North American Echocardiography Course on Congenital Heart Disease, Stanford University, Palo Alto, CA, Course cancelled due to COVID-19 pandemic. Apr 2020.
Mercer-Rosa L. "Methods and Techniques for Cardiac Characterization" 23rd Annual Update on Pediatric and Congenital Cardiovascular Disease, Orlando, FL. Feb 2020.
Mercer-Rosa L. "How Should We Use Echocardiography to Assess RV Function?", 23rd Annual Update on Pediatric and Congenital Cardiovascular Disease, Orlando, FL. Feb 2020.
Mercer-Rosa L. Visiting Professor, "The Long and Winding Road to Echocardiographic Characterization of the Right Ventricle", University of Colorado, Denver, Denver, CO. Jan 2020.
2019
Mercer-Rosa L. "How to set up a research program: Challenges, Joys and Frustrations" Faculty Seminar, University of California San Francisco Benioff Children's Hospital, San Francisco, CA. Oct 2019.
Mercer-Rosa L. Visiting Professor, "Tetralogy of Fallot: New Data from an Old Disease: 10 years of Research" Grand Rounds Lecture at "Bridging the Gap: Seminars on Balance and Diversity in Academic Pediatric Cardiology", University of California San Francisco Benioff Children's Hospital, San Francisco, CA. Oct 2019.
Mercer-Rosa L. "How to Choose a Research Project" Fellow Seminar, University of California San Francisco Benioff Children's Hospital, San Francisco, CA. Oct 2019.
Mercer-Rosa L. "Tetralogy of Fallot: post-operative echocardiography", 4th Echocardiography Course on Congenital Heart Disease, The Hospital for Sick Children's Daniels Hollywood Theatre, Toronto, Canada. Apr 2019.
Mercer-Rosa L. "Assessment of right ventricular systolic and diastolic function", 4th Echocardiography Course on Congenital Heart Disease, The Hospital for Sick Children's Daniels Hollywood Theatre, Toronto, Canada. Apr 2019.
Mercer-Rosa L. "What determines outcomes in tetralogy of Fallot?", 4th RV Symposium, The Hospital for Sick Children, Toronto, Canada. Apr 2019.
Mercer-Rosa L. "Evaluation of Right Ventricular Function" 48th Critical Care Congress, San Diego, CA. Feb 2019.
Mercer-Rosa L. "Imaging Characterization of the Failing RV" 22nd Annual Update on Pediatric and Congenital Cardiovascular Disease, Huntington Beach, CA. Feb 2019.
Mercer-Rosa L. "Strain, Synchrony and Other Advanced Tools for Assessing Heart Function Using Echo", 22nd Annual Update on Pediatric and Congenital Cardiovascular Disease, Huntington Beach, CA. Feb 2019.
Editorials, Reviews, Chapters
2018
Tang J, Mercer-Rosa L: Hypoplastic Left Heart Syndrome. The 5-Minute Pediatric Consult, 6th Edition. Schwartz, MW (eds.). 2018.
2008
Mercer-Rosa L, Malreany M. Hypoplastic Left Heart Syndrome. In: The 5-minute Pediatric Consult. Schwartz MW, editor. 5th ed. Philadelphia: Lippincott & Williams; 2008. p 434-435.