Dr. Osterhoudt is an attending physician in the Division of Emergency Medicine and the medical director of the Poison Control Center at The Children's Hospital of Philadelphia (CHOP), and is professor of Pediatrics at The Children's Hospital of Philadelphia and the University of Pennsylvania School of Medicine. Dr. Osterhoudt is an Associate Fellow for the Center for Injury Prevention and Research at CHOP, and is an Associate Scholar in the Center for Global Health and a faculty member in the Community Outreach and Education Core of the Center of Excellence in Environmental Toxicology at Penn. He has co-authored over 100 journal articles and textbook chapters, and serves on the editorial boards of Pediatric Emergency Care and Clinical Toxicology.
Dr. Osterhoudt is recognized for teaching excellence and was awarded the David Cornfeld Bedside Teaching Award by The Children's Hospital of Philadelphia in 2005, the Scott Mackler Award for Excellence in Teaching by the University of Pennsylvania in 2008, and the ACMT Award for Significant Contributions to the Educational Pursuits of Medical Toxicology by the American College of Medical Toxicology in 2009. In 2016, Dr. Osterhoudt was recognized as an Alan R. Cohen Master Clinician at CHOP, and was inducted into Penn Medicine’s Academy of Master Clinicians in 2020. He has served nationally on the Board of Directors of the American College of Medical Toxicology, as the American Board of Pediatrics' representative to the medical toxicology sub-board, and on the Executive Committee of the Council on Environmental Health of the American Academy of Pediatrics. He is currently a member of the Executive Committee of the AAP’s Council on Injury, Violence, and Poisoning Prevention.
Dr. Osterhoudt's academic interests include the clinical epidemiology and risk assessment of pediatric poisoning exposures, and methemoglobinemia disorders during infancy.
Education and Training
MD - State University of New York at Buffalo School of Medicine, NY
Pediatrics - The Children's Hospital of Philadelphia, Philadelphia, PA
Pediatrics - The Children's Hospital of Philadelphia, Philadelphia, PA
Pediatric Emergency Medicine - The Children's Hospital of Philadelphia, Philadelphia, PA
Research Fellow, Clinical Toxicology - The Children's Hospital of Philadelphia, Philadelphia, PA
Medical ToxicologyPediatric Emergency Medicine – American Board of PediatricsPediatrics – American Board of Pediatrics
MS in Clinical Epidemiology - University of Pennsylvania, Philadelphia, PA
Titles and Academic Titles
Medical Director, The Poison Control Center
Director, Section of Clinical Toxicology
Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania
Turner C, Powell MA, Finalle RR, Westmoreland K, Osterhoudt KC, Paulino RC, Lowenthal ED. Talking trash: perspectives on community environmental health in the Dominican Republic. PLoS One 2021; 16: e024843.
Miller SW, Osterhoudt KC, Korenoski AS, Patel K, Vaiyapuri S. Exotic snakebites reported to Pennsylvania poison control centers: Lessons learned on the demographics, clinical effects, and treatment of these cases. Toxins 2020; 12: 755.
Gaw CE, Lim CG, Korenoski AS, Osterhoudt KC. Beverage ethanol exposures among infants reported to United States Poison Centers. Clin Toxicol 2020; 59: 619-627.
Gaw C, Osterhoudt KC. Ethanol intoxication of young children. Pediatr Emerg Care 2019; 35: 722-732.
Coughlin K, Flibotte J, Cahill AM, Osterhoudt K, Hedrick H, Vrecenak J. Methemoglobinemia in an infant after sclerotherapy with high dose doxycycline. Pediatrics 2019; 143: e20181642.
Henretig FM, Calello DP, Burns MM, O’Donnell KA, Osterhoudt KC. Predictable, preventable and deadly: Epidemic carbon monoxide poisoning after storms. AmerJPubHealth 2018; 108: 1320-1321.
Kowalski JM, Kopec KT, Lavelle J, Osterhoudt KC. A novel agent for management of agitated delirium: a case series of ketamine utilization in the pediatric emergency department. Pediatr Emerg Care 2017; 33: e58-e62.
Hendel G, Trella J, Osterhoudt KC. Rising cost of antidotes in the US: Cost comparison of 2010 to 2015. Clin Toxicol 2017; 55: 360-363.
Corwin DJ, Topjian A, Banwell BL, Osterhoudt K. Adverse events associated with a largedose of lipid emulsion for suspected local anesthetic toxicity. Clin Toxicol 2017; 55: 603-607.
Osterhoudt KC, Hernandez R, Bassett RA. Succimer / CaNa2EDTA combination therapy for non-encephalopathic children with blood lead concentration > 100 mcg/dL: a report of five cases. J Med Toxicol 2021; 17: 98.
Osterhoudt KC, Demarco M, Nolan J, Singh B, Shaw LM, Lockman JL. Critical illness from an exploratory ingestion of a “homeopathic” remedy mailed from Pakistan: caffeine / yohimbine poisoning of a young child. J Med Toxicol 2021; 17: 145-146.
Bouchelle Z, Lim D, Polsky T, Osterhoudt K. Qualitative tricyclic antidepressant (TCA) serum testing in an urban children’s hospital has sad value. Clin Toxicol 2020; 58: 1195.
Gray H, Obilom C, Smollin C, Camarena-Michel A, Calello D, Osterhoudt K. Phencyclidine (PCP) exposure cases among young children reported to five U.S. statewide poison control center systems, 2009-2018. Clin Toxicol 2020; 58: 1195-1196.
Dewey A, Korenoski A, Osterhoudt K. Marijuana exposures of young children in Pennsylvania and Delaware as reported to Pennsylvania Poison Centers, July 2014-June 2019. Clin Toxicol 2020; 58: 1196.
Angirekula V, Fitzpatrick D, Schneider A, Schatzman A, Trella J, Osterhoudt K. Near-syncope, vomiting, hypertension, and metabolic acidosis after IV iron sucrose self-administration with serum iron levels. Clin Toxicol 2020; 58: 1197.
Osterhoudt K, Singh B, Teng C, Mercado O, Scribano P, Henretig F. Diagnosis of pediatric fentanyl poisoning confounded by suboptimal urine drug screening and by medical fentanyl administration. Clin Toxicol 2020; 58: 1196-1197.
Gray H, Osterhoudt KC. Phencyclidine (PCP) exposures among young children reported to U.S. poison control centers: 2009-2018. Pediatric Academic Societies 2020, Philadelphia, PA.
Gaw C, Osterhoudt KC. Ethanol exposures among infants reported to United States poison control centers. Pediatric Academic Societies 2020, Philadelphia, PA.
Longo L, McQueen J, Fox M, Nguyen TT, Block T, Osterhoudt KC. Utility of four smartphone applications in the identification of poisonous plants. J Med Toxicol 2020; 16: 150.
Rood J, White BF, Thomas AR, Ronan J, Fitzgerald J, Osterhoudt KC. Prolonged obtundation and choreoathetosis following pediatric exploratory phencyclidine (PCP) ingestion with serum concentration measurement. J Med Toxicol 2020; 16: 167.
Miller SW, Korenoski A, Gereg I, Osterhoudt KC. Global snake envenomations in our own backyard: exotic venomous snakebites in Pennsylvania reported to PA poison centers. J Med Toxicol 2020; 16: 160.
O’Malley H, Schneider A, Nham Q, Trella J, Bassett R, Osterhoudt KC. Opioid urine drug screening capabilities of hospital emergency departments in Delaware and Eastern Pennsylvania – 2019. J Med Toxicol 2020; 16: 142.
Sing J, Tang PH, Nham Q, Lynch M, Trella J, Osterhoudt KC. E-cigarette and vaping-associated lung injury (EVALI) in Pennsylvania and Delaware as reported to Pennsylvania Poison Centers – 2019. J Med Toxicol 2020; 16: 149.
Weiss S, Cueto-Vilorio V, Barolia D, Ahmed A, Mohiuddin K, Simpson S, Walsh S, Osterhoudt K. Analysis of 10 years of intentional lurasidone overdoses using national poison center data. Clin Toxicol 2019; 57: 986-987.
Bassett R, Black C, Henretig F, Trella J, Osterhoudt K. Total bilirubin: not a total waste of time in naproxen toxicity. Clin Toxicol 2019; 57: 881.
Dela Cruz M, Bodenstab H, Vearrier D, Osterhoudt K. Review of recommendations for use of intravenous sodium bicarbonate to treat salicylate poisoning. Clin Toxicol 2019; 57: 889.
McCabe K, Polsky TG, Osterhoudt KC. Challenges in the implementation of a urine immunoassay for buprenorphine at a children’s hospital. J Med Toxicol 2019; 15: 54.
Abbadessa MK. Henretig FM, Osterhoudt KC. “Partial-thickness skin burn of a 2 year-old boy’s neck from contact with an undissolved single-use laundry detergent sac adherent to clothing after laundering.” J Med Toxicol 2019; 15: 99.
Dela Cruz, M, Vearrier D, Behrman A, Hofman M, Osterhoudt K. Occupationaldermal exposure to alpha-amanitin: alarm, and disparity, in safety data sheets. J Med Toxicol 2019; 15: 102.
Osterhoudt KC. “How Physicians and Healthcare Providers Play a Role in Lead Poisoning Prevention”. Lead Safe Allegheny / Women for a Healthy Environment, Pittsburgh, PA (Virtual). Oct 2021.
Osterhoudt KC. “Childhood Lead Poisoning: Sources and Mitigation”. PA AAP Lead Testing Echo, Harrisburg, PA (Virtual). Oct 2021.
Osterhoudt KC. “Blood Lead Reference Value & How to Interpret Results”. PA AAP Lead Testing Echo, Harrisburg, PA (Virtual). Aug 2021.
Osterhoudt KC. “Of Plagues and Poisons: Pediatric Poisoning During0 a Pandemic”. Cohen Children’s Medical Center PEM Symposium, New York, NY (Virtual). May 2021.
Osterhoudt KC. “Psychostimulant Drugs: The Poison Center’s Perspective”. 2020 Pennsylvania Psychostimulant Symposium. PA Department of Drug and Alcohol Programs, Harrisburg, PA (Virtual). Nov 2020.
Osterhoudt KC. “Pediatric Toxicology: Epidemiology, Evaluation & Management”. World Congress of Emergency Medicine, Mexico City, Mexico (Virtual). Nov 2020.
Osterhoudt KC. “The Highs (and Lows) of Synthetic Cannabinoids”, “Hot Topic: Neonatal Fever”, “Eye Captain! Evaluation of Traumatic Eye Injuries”, “Toxicology Jeopardy”, Symposia Medicus’ 20th Annual Fall Conference on Emergency Medicine. Grand Cayman, Cayman Islands. Nov 2019.
Osterhoudt KC. “Keeping the ED Afloat in a Sea of Functional Pain”. Intensive Course in Pediatric Emergency Medicine. Children’s Hospital of Philadelphia, Philadelphia, PA. Nov 2019.
Osterhoudt KC. “Toddlers and Up: Unintentional Exposure, Prevention, Treatment”. AAP National Conference and Exhibition: Peds21 Program, New Orleans, LA. Oct 2019.
Osterhoudt KC. “Fat Chance of Survival: Intravenous Lipid Emulsion for Oral Cardiovascular Toxicant Poisoning”. Bruce K. Fehr Memorial Lecture, Children’s Hospital Minnesota, Minneapolis, MN. Sept 2019.
Osterhoudt KC. “Drugs of Abuse”, “Pediatric Considerations in Toxicology”, “Toxicology of Anti-Diabetic and Anti-Convulsant Medications”, “Management of Foreign Body Ingestion”. Romanian Combined EM Residency Course in Toxicology, Targu Mures, Romania. Sept 2019.
Osterhoudt KC. “The Lows of Getting High: Focus on Opioids and Cannabinoids”. Princeton University Health Services Lecture Series, Princeton, NJ. Mar 2019.
Osterhoudt KC. “History of Poison Control in Philadelphia”. AAPCC National Directors’ Meeting, Philadelphia, PA. Feb 2019.
Awards and Honors
2021, ACMT Best Original Research Platform Presentation Award, American College of Medical Toxicology
2021, Academy of Master Clinicians, Perelman School of Medicine at the University of Pennsylvania
2016, Alan R Cohen Master Clinician Award, The Children’s Hospital of Philadelphia
2014, Top Peer Reviewer, Annals of Emergency Medicine
2011, Certificate of Appreciation, Delaware Coalition for Injury Prevention
2009, CHOP Emergency Medicine Faculty Teacher of the Year Award, York Hospital Emergency Medicine Residency Program
2009, ACMT Award for Significant Contributions to the Educational Pursuits of Medical Toxicology, American College of Medical Toxicology
2008, Scott Mackler Award for Excellence in Substance Abuse Teaching, The University of Pennsylvania School of Medicine
2006-2007, 2011, Letter of Commendation for Quality Peer Review, Pharmacoepidemiology and Drug Safety
2005, Class of 1990 David Cornfeld Bedside Teaching Award, The Children’s Hospital of Philadelphia
2004-2008, Top Consultant award, Annals of Emergency Medicine
1999-2009, 2011-2012, Department of Pediatrics, Teaching Honor Roll, The Children's Hospital of Philadelphia
1995-1996, 1998-2004, 2006-2007, The Jean A. Cortner Divisional Teaching Award, The Children’s Hospital of Philadelphia
2001, Best Discussant, 2001 Case Presentation Competition, North American Congress of Clinical Toxicology, Montreal
1997, Commencement Speaker, Westfield Academy and Central School, Westfield, NY
1995, Pediatric Advanced Life Support Excellence Award, National Institute of Emergency Care
1990, Alpha Omega Alpha medical honor society
1989, Research Fellowship, SUNY Buffalo School of Medicine
1988, Dean’s Commendation for Academic Excellence in Research, SUNY Buffalo School of Medicine
1988, Research Fellowship, SUNY Buffalo School of Medicine
1984, Teaching Assistantship, Department of Biology, R.I.T.
1983, Reserve Officers Association of America Memorial Scholarship
1981, Bausch and Lomb Medal in Science
1981, Valedictorian, Westfield Academy and Central School
Editorial and Academic Positions
2021, Ad hoc Reviewer, Toxicology Communications
2020, Ad hoc Reviewer, Journal of Adolescent Health
2015-present, Senior Editorial Board, Clinical Toxicology
2014-present, Associate Editor, Pediatric Emergency Care
2001-present, Reviewer, Clinical Toxicology
2000, 2003-present, Reviewer, Annals of Emergency Medicine
2000, 2003-present, Reviewer, Pediatrics
1994-present, Reviewer, Pediatric Emergency Care
2016-present, Advisory Board, Integrative Medicine Program
2008-present, Therapeutic Standards Committee,
2008-preesent, Adverse Drug Reaction Committee
2008-present, Stakeholder Advisory Board, Community Outreach and Education Core of the Center for Excellence in Environmental Toxicology
Leadership and Memberships
Memberships in Professional Organizations
American Academy of Pediatrics, fellow
- 2021-present, Executive Committee, Council on Injury, Violence, Poison Prev
American College of Medical Toxicology, fellow
- 2013-present, International Tox Section
American Academy of Clinical Toxicology, fellow
American Board of Pediatrics
American Association of Poison Control Centers
Patient Experience Ratings
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