Lubica Rauova, MD, PhD

Papers

2016

Khandelwal S, Lee GM, Hester CG, Poncz M, McKenzie S, Sachais BS, Rauova L, Kelsoe G, Cines DB, Frank M, Arepally GM: The antigenic complex in HIT binds to B-cells via complement and complement receptor 2 (CD21). Blood July 2016 Notes: epub ahead of print.

Tutwiler V, Madeeva D, Ahn HS, Andrianova I, Hayes V, Zheng XL, Cines DB, McKenzie SE, Poncz M and Rauova L: Platelet transactivation by monocytes promotes the prothrombotic state in heparin-induced thrombocytopenia. Blood 127(4): 464, Feb 2016.

Parker ZF, Rux AH, Riblett AM, Lee FH, Rauova L, Cines DB, Poncz M, Sachais BS, Doms RW.: Platelet-Factor 4 (PF4) inhibits and enhances HIV-1 infection in a concentration-dependent manner by modulating viral attachment. AIDS Res Hum Retroviruses Feb 2016 Notes: Epub ahead of print.

2015

Zhou J, Wu Y, Wang L, Rauova L,Hayes VM, Poncz M, and Essex DW: The second CGHC motif of protein disulfide isomerase mediates thrombosis. Journal of Clinical Investigation 25(12): 4391, Nov 2015.

Cai Z, Yarovoi SV, Zhu Z, Rauova L, Hayes V, Lebedeva T, Liu Q, Poncz M, Arepally G, Cines DB, Greene MI: Atomic description of the immune complex involved in heparin-induced thrombocytopenia. Nature Communications 6(8277): 9277, Sep 2015.

Joglekar M, Khandelwal S, Cines DB, Poncz M, Rauova L, Arepally GM.: Heparin enhances uptake of platelet factor 4/heparin complexes by monocytes and macrophages. J Thromb Haemost. 13(8): 1416-27, Aug 2015.

2014

Zhou J, Wu Y, Wang L, Rauova L, Hayes VM, Poncz M, Essex DW.: The disulfide isomerase ERp57 is required for fibrin deposition in vivo. J Thromb Haemost 12(11): 1890-1897, Nov 2014.

Skewis LR, Lebedeva T, Papkov V, Thayer EC, Massefski W, Cuker A, Nagaswami C, Litvinov RI, Kowalska MA, Rauova L, Poncz M, Weisel JW, Lowery TJ, Cines DB: T2 Magnetic Resonance: A Diagnostic Platform for Studying Integrated Hemostasis in Whole Blood-Proof of Concept. Clin Chem 60(9): 1174-82, September 2014.

Cuker A, Rauova L, Bolgiano D, Matthai WH Jr, Poncz M, Konkle BA.: Atherosclerosis is not a risk factor for anti-platelet factor 4/heparin antibody formation after cardiopulmonary bypass surgery. Thromb Haemost 111(6): 1191-3, Jun 2014.

Cines DB, Lebedeva T, Nagaswami C, Hayes V, Massefski W, Litvinov RI, Rauova L, Lowery TJ, Weisel JW.: Clot contraction: compression of erythrocytes into tightly packed polyhedra and redistribution of platelets and fibrin. Blood 123(10): 1596-1603, Mar 2014.

Books

Chapters

2012

Rauova L, Arepally GM, Cines DB, Poncz M: Cellular and molecular immunopathogenesis of heparin induced thrombocytopenia.  Heparin Induced Thrombocytopenia 5th Ed. Theodore E Warkentin and Andreas Greinacher (eds.). Informa Healthcare, Page: 230-251, Oct 2012.

Arepally GM, Sachais BS , Cines DB , Poncz M , Rauova L, McKenzie SM: : Murine models of heparin-induced thrombocytopenia.  Heparin Induced Thrombocytopenia 5th Ed. Theodore E Warkentin and Andreas Greinacher (eds.). Informa Healthcare, Page: 252-71, Oct 2012.

2002

Gilburd B, Rauova L, Nesher Y, Shoenfeld Y. : Evaluation study on a new anti-ß2-glycoprotein I screening EIA.  Autoantigens and Autoantibodies: Diagnostic Tools and Clues to Understanding Autoimmunity.   K. Conrad, R.-L. Humbel, M. Meurer, Y. Shoenfeld, E. M. Tan.  (eds.). Pabst Science Publishers, 2002.

2001

Rauova L, Chapman J, and Shoenfeld Y: Brain vasculitis and antiphospholipid syndrome. Brain Disease: Therapeutic Strategies and Repair. Oded Abramsky, D Alastair S Compston, Ariel Miller, Gerard Said  (eds.). Taylor & Francis, A Martin Dunitz Book, Page: 193, 2001.

2000

Rauova L.: [Primary Immunodeficiency Syndromes].  Klinicka reumatologia [Clinical Rheumatology].  Rovensky J. and Pavelka K. (eds.). Osveta Martin  Page: 629-635, 2000 Notes: In Slovak.

Rauova L, Rovensky J: [Immunodeficiency and  Arthritis].  Klinicka reumatologia [Clinical Rheumatology].  Rovesnky J. and Pavelka K. (eds.). Osveta Martin 2000, Page: 635-641, 2000 Notes: In Slovak.

1993

Rovensky J, Pekarek J, Lukac J, Rauova L, Niepel G, Cech K, Blazickova S: Immunoterapeutische Beeinfussung verschiedener  Vaskulitisformen. Erkrankungen  mit Immunpathogenese. Neue Therapiemöglichkeiten.  Metzner, G., Wissler, J. H. (eds.). München, Bern,  Wien, New York, W. Zuckschwerdt Verlag  Page: 89-93, 1993 Notes: In German.

1991

Rauova, L., Pekarek, J. : DLE  in the therapy of juvenile chronic arthritis.  Recent advances in Transfer Factor and Dialyzable Leukocyte Extracts.  Fujisawa T, Saskawa S, Iikkura Y, Komatsu F, Yamaguchi Y. (eds.). Tokyo, Japan: Maruzen Co. Ltd. Page: 323-325, 1991.

Posters and Presentations

2015

Junsong Zhou, Yi Wu, Lu Wang, Lubica Rauova, Vincent M Hayes, Mortimer Poncz, David W Essex: The Second CGHC Motif of Protein Disulfide Isomerase Mediates Thrombosis. Blood (ASH Annual Meeting Abstracts)  126: 3461, December 2015 Notes: Poster Presentation.

Izabella Andrianova, Vincent M Hayes, Daria Madeeva, Rustem I. Litvinov, Douglas B. Cines, Mortimer Poncz, John W. Weisel, Lubica Rauova: Membrane Remodeling By Pathogenic Antibodies Underlies Monocyte Activation in Heparin-Induced Thrombocytopenia. Blood (ASH Annual Meeting Abstracts)  126: 2244, December 2015 Notes: Poster Presentation.

Grace M. Lee, Manali Joglekar, Sanjay Khandelwal, Rui Qi, Lubica Rauova, Gowthami M Arepally: Characterization of Human and Murine Anti-Protamine/Heparin Antibodies. Blood (ASH Annual Meeting Abstracts)  126: 3461, December 2015 Notes: Poster Presentation.

2014

Zheng Cai, Serge V. Yarovoi, Zhiquiang Zhu, Lubica Rauova, Tatiana Lebedeva, Mortimer Poncz, Gowthami M Arepally, Douglas B. Cines, Mark I. Greene: Atomic Level Description of the Immune Complex That Causes Heparin-Induced Thrombocytopenia (HIT). Blood (ASH Annual Meeting Abstracts)  124(21): 465, December 2014 Notes: Oral Presentation.

Yulia V. Skibo, Alia R. Fathullina, Elvira V. Romanova, Lubica Rauova, Rustem I. Litvinov: Anti-Apoptotic Effects of Platelet Factor 4 on Human T-Lymphocytes. Blood (ASH Annual Meeting Abstracts)  Poster Presentation, 124(21): 1418, December 2014 Notes: Poster.

Vincent Hayes, Ian Johnston, Douglas B. Cines, Lubica Rauova, Mortimer Poncz: New Insights into the Prothrombotic State of Heparin-Induced Thrombocytopenia (HIT) Using a Novel Microfluidic System: The Endothelial Lining and "Rolling Barrage" of Activation. Blood (ASH Annual Meeting Abstracts)  124(21): 574, December 2014 Notes: Oral Presentation.

Manali V. Joglekar, Sanjay Khandelwal, Mortimer Poncz, Lubica Rauova, Gowthami M Arepally: Understanding the Underlying Immune Response in HIT: Uptake of PF4/Heparin Complexes By Monocytes & Dendritic Cells. Blood (ASH Annual Meeting Abstracts)  124(21): 4197, December 2014 Notes: Poster Presentation.

Daria Madeeva, Valerie Tutwiler, Douglas B. Cines, Mortimer Poncz, Lubica Rauova: FcγRIIA Mediates the Prothrombotic Role of Monocytes in HIT. Blood (ASH Annual Meeting Abstracts)  124(21): 575, December 2014 Notes: Oral Presentation.