Amanda J. Shillingford, MD, FACC

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Amanda J. Shillingford, MD, FACC, is an attending physician in the Cardiac Center at Children's Hospital of Philadelphia and the Medical Director of the Fetal Heart Program Annex at CHOP’s Bryn Mawr Specialty Care Center.

Areas of Expertise: Fetal cardiology, Fetal echocardiography, General echocardiography, Transesophageal echocardiography, General pediatric cardiology, Care of complex congenital heart disease
Locations: Main Hospital; Pediatric Cardiologists in Brandywine Valley, PA

Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

Education and Training

Medical School

MD - College of Physicians & Surgeons of Columbia University, New York, NY


Pediatrics - Children’s Hospital of Philadelphia, Philadelphia, PA


Pediatric Cardiology - Children’s Hospital of Philadelphia, Philadelphia, PA
Pediatric Echocardiography and Fetal Cardiology - Children’s Hospital of Philadelphia, Philadelphia, PA (Senior Fellow)p

Board Certification

Pediatric Cardiology – American Board of Pediatrics
Pediatrics – American Board of Pediatrics

Titles and Academic Titles

Attending Physician

Medical Director, Fetal Outreach

Medical Director, Fetal Heart Program Annex at CHOP’s Bryn Mawr Specialty Care Center

Associate Professor of Clinical Pediatrics, Perelman School of Medicine at the University of Pennsylvania

Departments and Services




Colette Gramszlo,PhD, Allison Karpyn, PhD, Abigail C. Demianczyk,PhD, Amanda Shillingford, MD, Erin Riegel, MBA, Anne E. Kazak, PhD, ABPP, Erica Sood, PhD: Parent Perspectives on Family-Based Psychosocial Interventions for Congenital Heart Disease. The Journal of Pediatrics 216: 51-57, January  2020.

Goldberg DJ, Zak V, Goldstein BH, Schumacher KR, Rhodes J, Penny DJ, Petit CJ, Ginde S, Menon SC, Kim SH, Kim GB, Nowlen TT, DiMaria MV, Frischhertz BP, Wagner JB, McHugh KE, McCrindle BW, Shillingford AJ, et al.; : Pediatric Heart Network Investigators. Results of the FUEL Trial. Circulation 141(8): 641-651, February 2020.


Miller TA, Zak V, Shrader P, Ravishankar C, Pemberton VL, Newburger JW, Shillingford AJ, Dagincourt N, Cnota JF, Lambert LM, Sananes R, Richmond ME, Hsu DT, Miller SG, Zyblewski SC, Williams RV; Pediatric Heart Network Investigators. Growth Asymmetry, Head Circumference, and Neurodevelopmental Outcomes in Infants with Single Ventricles. .J Pediatr. 2016 Jan;168:220-5. Epub 2015 Oct 17

Loomba RS, Geddes G, Shillingford AJ, Hehir DA. Practice variability in management of infectious issues in heterotaxy: A survey of pediatric cardiologists. Congenit Heart Dis. 2017 May;12(3):332-339

Margossian R, Zak V, Shillingford AJ, Hlavacek AM, Cnota JF, Puchalski MD, Levine JC, McCrindle BW, Cohen MS, Altmann K, Barker PC, Hsu DT, Colan SD; Pediatric Heart Network Investigators. The Effect of the Superior Cavopulmonary Anastomosis on Ventricular Remodeling in Infants with Single Ventricle. J Am Soc Echocardiogr. 2017 Jul;30(7):699-707

Plymale JM, Frommelt PC, Nugent M, Simpson P, Tweddell JS, Shillingford AJ. The Infant with Aortic Arch Hypoplasia and Small Left Heart Structures: Echocardiographic Indices of Mitral and Aortic Hypoplasia Predicting Successful Biventricular Repair.  Pediatr Cardiol. 2017 Aug;38(6):1296-1304

Callahan C, Saudek D, Shillingford A, Creighton S, Hill Garick, Johnson W, Tweddell JS, Mitchell ME, Woods RK.  Single-stage repair of coarctation of the aorta and ventricular septal defect: a comparison of surgical strategies and resource utilization.  World J Pediatr Congenit Heart Surg 2017; 8(5): 559-563.

Tsuda T, Shillingford AJ, Vetter J, Kandula V, Jain B, Temple J.  Transient ischemic attack and ischemic stroke in Danon disease with formation of left ventricular apical thrombus despite normal systolic function.  Case Rep Pediatr. 2017;2017


Marino BS, Goldberg DJ, Dorfman AL, King E, Kalkwarf H, Zemele B, Smith M, Pratt J, Fogel MA, Shillingford AJ, et al.  Abnormalities in Serum Biomarkers Correlate with Lower Cardiac Index in the Fontan Population. Accepted for Publication. Cardiology in the Young Jan. 12 2016.

Loomba, R, Geddes G, Basel D, Benson D, Leuthner S, Hehir D, Ghanayem N, Shillingford AJ. Bacteremia in patients with heterotaxy: a review and implications for management. Congenit Heart Dis. 2016 Dec;11(6):537-547


Loomba RS, Frommelt M, Moe D, Shillingford AJ.  Agenesis of the venous duct: two cases of extrahepatic drainage of the umbilical vein and extrahepatic shunt with review of the literature. Cardiol Young. 2015 Feb; 25(2):208-17.

Landisch R, Abdel-Hafeez A, Massoumi R, Christensen M, Shillingford A, Wagner A Observation versus prophylactic Ladd procedure for asymptomatic intestinal rotational abnormalities in heterotaxy syndrome: A systematic review. J Ped Surg.  2015 Nov 11 50(11) 1971.


Shillingford AJ, Glanzman MM, Ittenbach RF, Clancy RR, Gaynor JW, Wernovsky G.  Inattention, Hyperactivity, and School Performance in a Population of School-Age Children with Complex Congenital Heart Disease.  Pediatrics. 2008 Apr: 121(4):e759-e767.


Shillingford AJ, Ittenbach RF, Marino BS, Rychik J, Clancy RR, Spray TL, Gaynor JW, Wernovsky G. Aortic Morphometry and Microcephaly in Hypoplastic Left Heart Syndrome. Cardiol Young. 2007 Apr; 17(2):189-95.


White SA, Hoeger M, Schweppe JJ, Shillingford A, Shipilov V, Zarutskie J.  Internal loop mutations in the ribosomal protein L30 binding site of the yeast L30 RNA transcript.  RNA. 2004 Mar;10(3):369-77.  



Somya Shankar, BS; Jill J. Savla, MD, MSCE; Amanda J. Shillingford, MD; Christine Falkensammer, MD; Karl Degenhardt, MD, PhD; Shobha Natarajan, MD; Michael Quartermain, MD; Zhiyun Tian, MD; Anita L. Szwast, MD; Jack Rychik, MD: Clinical Characteristics of Absent Ductus Venosus in the Fetus and Associated Postnatal Outcomes Cardiology 2019: Annual Update on Pediatric and Congenital Cardiovascular Disease February 2019.

Bradley S. Marino, MD, MPP, MSCE, Amy Cassedy, PhD, Adam L. Dorfman, MD, Michael Taylor, MD, Mark Fogel, MD, Alvin Chin, MD, Caren Goldberg, MD, David J. Goldberg, MD, Bryan H. Goldstein, MD, David Gremmels, MD, Marshall L Jacobs, MD,  Anitha S. John, MD, PhD, Heidi Kalkwarf, PhD, Eileen King, PhD, David Overman, MD, Christina Phelps, MD, Robert Stewart, MD, Babette Zemel, PhD, Amanda J. Shillingford*, MD, Lazaros Kochilas*, MD, *Co-senior Authors.: Serum Biochemical Biomarkers Predict Lower Cardiac Index in Adolescents and Young Adults with Fontan Circulation.  2019 American Heart Association Scientific Sessions November 2019.


Demianczyk AC, Karpyn A, Ryan J, Shillingford AJ, Kazak AE, Sood E: Parenting a child with congenital heart disease: An examination of coping strategies utilized by mothers and fathers.   14th Annual International Meeting of the Pediatric Cardiac Intensive Care Society, Miami, FL  December 2018.




Kirkpatrick E, Shillingford AJ: Echocardiography in ICU. Pediatric Cardiology, Cardiac Surgery and Intensive Care. DaCruz EM, Ivy DD, Hraska V, Jaggers J (eds.). Springer, 2018 Notes: In press.


Kirkpatrick E, Shillingford AJ, Cohen MS.  Echocardiography in ICU.  In: Da Cruz EM, Ivy DD, Hraska V, Jaggers J, eds.  Pediatric Cardiology, Cardiac Surgery and Intensive Care.  Springer; 2013.  


Shillingford AJ.  Truncus Arteriosus.  In: Rychik J, Tian Z, eds.  Fetal Cardiovascular Imaging.   Elsevier Saunders Publishing; 2012.

Shillingford AJ.  Tetralogy of Fallot with absent pulmonary valve syndrome.  In: Rychik J, Tian Z, eds. Fetal Cardiovascular Imaging.  Elsevier Saunders Publishing; 2012.

Shillingford AJ.  Tetralogy of Fallot with pulmonary atresia. In: Rychik J, Tian Z, eds. Fetal Cardiovascular Imaging.  Elsevier Saunders Publishing; 2012.

Shillingford AJ.  Tetralogy of Fallot. In: Rychik J, Tian Z, eds. Fetal Cardiovascular Imaging.  Elsevier Saunders Publishing; 2012.


Shillingford AJ. Wernovsky G. The central nervous system in children and young adults with congenital cardiac disease. In: Anderson R, Baker E, Penny D, Redington A, Rigby M, Wernovsky G, eds.  Paediatric Cardiology, 3rd edition. Elsevier Saunders Publishing; 2010.


Shillingford AJ, Rychik J. Impact of congenital heart disease on the central nervous system in the developing fetus. In: Yagel S, Silverman N, Gembruch, eds. Fetal Cardiology, 2nd edition. Informa Healthcare Publishing; 2009.

Posters and Presentations

Invited Lectures


Shillingford A. "Conotruncal Anomalies: TOF and DORV", 12th Prenatal pregnancy Conference, Philadelphia, PA. June 2020.


Shillingford A. "Early Fetal Cardiac Imaging", 11th Annual Ultrasound in Obstetrics and Gynecology Symposium, Lehigh Valley Hospital, Allentown, PA. Nov 2019.

Shillingford A. "Heart Care Before Birth: Innovative Strategies for Diagnosis and Management of the fetal CV System", 11th Annual Ultrasound in Obstetrics and Gynecology Symposium, Lehigh Valley Hospital, Allentown, PA. Nov 2019.

Shillingford A. "Echocardiography Evaluation: Pulmonary Valve, Aortic Valve, Coronary Arteries", Advanced Congenital Cardiac Morphology Children's Hospital of Philadelphia, Philadelphia, PA. Nov 2019.

Shillingford A. "Fetal Diagnosis and Management of Conotruncal Anomalies I: Tetralogy of Fallot and Double Outlet Right Ventricle", Focus on the Fetus 2019, Children's Hospital of Philadelphia, Philadelphia, PA. Nov 2019.


Shillingford A. Conotruncal Anomalies. The 10th Philadelphia Prenatal Diagnosis: Prenatal Genetics & Ultrasound, Obstetrics/MFM Conference, Philadelphia, PA. June 2018.

Shillingford A. Fetal Cardiology, Prenatal Diagnosis of Congenital Heart Disease: Impact on Outcome. Pediatric Grand Rounds, Nemours/ Alfred I. duPont Hospital for Children, Wilmington, Delaware. June 2018.

Shillingford A. “Twin-to-Twin Transfusion Syndrome for the Cardiologist”, Echo Lab Education Series. April 2018.

Shillingford A. “Heterotaxy Diagnosis in the Fetus”, Fetal Therapy Lecture Series, Delaware Center for Maternal Fetal Medicine. April 2018.

Shillingford A. Wilmington Heart Ball Keynote Lecture: Impact of Advocacy and Research in Pediatric Cardiology. American Heart Association Heart Ball, Wilmington, Delaware. February 2018.

Awards and Honors

2018, Keynote Speaker, Wilmington Heart Ball, American Heart Association Annual Heart Ball
2016, Resident Teaching Recognition, A.I. duPont Hospital for Children
2012 & 2013, Milwaukee’s Top Doctors
2005, First Place, Clinical Research, Children’s Hospital of Philadelphia Fellow Research Poster Day
2004, Young Investigator Award, First Prize Clinical Research, 2004 Scientific Sessions of the American Board of Pediatrics
2004, Ann Newman Fellow in Pediatric Cardiology, Children’s Hospital of Philadelphia
1997, NIH Summer Research Fellowship Recipient, College of Physicians & Surgeons Columbia University
1996, Ann E. Delano Award , Bryn Mawr College
1995, Merck Foundation Research Fellowship Recipient, Bryn Mawr College

Editorial and Academic Positions

Editorial Positions

2016-present, European Journal of Pediatrics; ad hoc reviewer
2014-present, Journal of Ultrasound in Medicine; ad hoc reviewer
2010-present, Pediatric Cardiology; ad hoc reviewer

Academic and Institutional Committees

2020-present, Cardiac Center Faculty Advisory Council
2019-present, Cardiology Liasion, Cardiac Developmental Follow-up Program

Leadership and Memberships

Memberships in Professional Organizations

2019-present, American College of Cardiology, Fellow
2015-present, American Heart Association
2006-present, American Society of Echocardiography
2006-present, National Pediatric Cardiology Quality Improvement Collaborative (Member)
2000-present, American Academy of Pediatrics