Alanna Strong, MD, PhD Alanna Strong, MD, PhD, is fellow in the Division of Human Genetics at Children's Hospital of Philadelphia. Locations: Main Campus Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467) Education and Training Medical SchoolMD - Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA ResidencyPediatrics - St. Christopher’s Hospital for Children, Philadelphia, PA FellowshipHuman Genetics - Children's Hospital of Philadelphia, PA Titles and Academic Titles Fellow, Human Genetics Fellowship Program Departments and Services Division of Human Genetics Publications Papers2017 Strong A, Musunuru K. (2017) Genome editing in cardiovascular diseases. Nat Rev Cardiol. 14(1): 11-20. 2016 Strong A, Musunuru K. (2016) The (pro)renin receptor and LDL clearance: an old player joins a new game. Circ. Res.117: 187-9. 2015 Patel KM, Strong A, Tohyama J, Jin X, Morales CR, Billheimer J, Millar JS, Kruth H, Rader DJ. (2015) Macrophage sortilin promotes LDL uptake, foam cell formation, and atherosclerosis. Circ. Res. 116: 789-796 2014 Strong A, Patel K, Rader DJ. (2014) Sortilin and lipoprotein metabolism: making sense out of complexity. Curr. Opin. Lipidol. 25:350-7. Bearden D, Strong A, Ehnot J, DiGiovine M, Dlugos D, Goldberg EM. (2014) Targeted treatment of migrating partial seizures of infancy with quinidine. Ann. Neurol. 76:457-61. Ding Q, Strong A, Patel KM, Ng SL, Gosis BS, Regan SN, Cowan CA, Rader DJ, Musunuru K. (2014) Permanent alteration of PCSK9 with in vivo CRISPR-Cas9 genome editing. Circ. Res. 115:488-92. 2012 Strong A, Ding Q, Edmondson AC, Millar JS, Sachs KV, Li X, Kumaravel A, Wang MY, Ai D, Guo L, Alexander ET, Nguyen D, Lund-Katz S, Phillips MC, Morales CR, Tall AR, Kathiresan S, Fisher EA, Musunuru K, Rader DJ. (2012) Hepatic sortilin regulates both apolipoprotein B secretion and LDL catabolism. J. Clin. Invest. 122: 2807-16. Strong A, Rader DJ (2012) Sortilin as a regulator of lipoprotein metabolism. Curr. Atheroscler. Rep. 14: 211-8. Ai D, Baez JM, Jiang H, Conlon DM, Hernandez-Ono A, Frank-Kamenetsky M, Milstein S, Fitzgerald K, Murphy AJ, Woo CW, Strong A, Ginsberg HN, Tabas I, Rader DJ, Tall AR. (2012) Activation of ER stress and mTORC1 suppresses hepatic sortilin-1 levels in obese mice. J. Clin. Invest. 122:1667-87. 2010 Musunuru K*, Strong A , Frank-Kamenetsky M, Lee NE, Ahfeldt T, Sachs KV, Li X, Li H, Kuperwasser N, Ruda VM, Pirruccello JP, Muchmore B, Prokunina-Olsson L, Hall JL, Schadt EE, Morales CR, Lund-Katz S, Phillips MC, Wong J, Cantley W, Racie T, Ejebe KG, Orho-Melander M, Melander O, Koteliansky V, Fitzgerald K, Krauss RM, Cowan CA, Kathiresan S, Rader DJ. (2010) From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus. Nature 466: 714-9. Strong A, Rader DJ. (2010) Clinical Implications of Lipid Genetics for Cardiovascular Disease. Current Cardiovascular Risk Rep. 4:461-8. Awards and Honors Saint Christopher’s Hospital For Children SEEDS Service Award Junior Investigator Award for Women, ATVB 2012 Scientific Sessions Edward Holmes Award in Bench Research – Dept. of Medicine, University of Pennsylvania Trainee Award in Predoctoral-Translational Research, American Society of Human Genetics Fellow, American Heart Association (AHA) Pre-doctoral Fellowship - Great Rivers Affiliate Summa cum laude with University Honors, University of Pennsylvania American Heart Association Grant National Institutes of Health T32 Grant Leadership and Memberships Memberships in Professional Organizations American Heart Association American Society of Human Genetics Patient Experience Ratings About the Patient Experience Rating System The Patient Experience Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question. Responses are measured on a scale of 1 to 5 with 5 being the best score. The comments are submitted by patients and families and reflect their views and opinions. The comments are not endorsed by and do not reflect the views of Children’s Hospital of Philadelphia.