Hilary Whitworth, MD

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Hilary Whitworth, MD, is an attending physician with the Division of Hematology at Children's Hospital of Philadelphia.

Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

Education and Training

Medical School

MD - Emory University School of Medicine, Atlanta, GA

Residency

Pediatrics - Children’s Hospital of Philadelphia, Philadelphia, PA

Fellowship

Pediatric Hematology and Oncology - Children’s Hospital of Philadelphia, Philadelphia, PA

Board Certification

Pediatrics – American Board of Pediatrics

Titles and Academic Titles

Attending Physician

Departments and Services

Publications

Papers

2022

Roe AH, McAllister A, Kete C, Pishko A, Whitworth H, Schreiber CA, Sayani FA. Sex as an independent risk factor for venous thromboembolism in sickle cell disease: A cross-sectional study. J Women's Health (Larchmt). 2022 Jun 8. doi: 10.1089/jwh.2022.0046. Epub ahead of print. PMID: 35675680.

Dain AS, Raffini L, Whitworth H. Thrombotic events in critically ill children with COVID-19 or MIS-C. Curr Opin Pediatr. 2022;34(3):261-267. PMID: 35634699

Whitworth H, Raffini L. Practical Considerations for Use of Direct Oral Anticoagulants in Children. Front Pediatr. 2022 Apr 1;10:860369. PMID: 35433559; PMCID: PMC9010784

Clark HH, Ballester L, Whitworth H, Raffini L, Witmer C. Prevention of Recurrent Thrombotic Events in Children with Central Venous Catheter-Associated Venous Thrombosis. Blood. 2022 Jan 20;139(3):452-460. PMID: 34727184

Strong A, March ME, Cardinale CJ, Kim SE, Merves J, Whitworth H, Raffini L, Larosa C, Copelovitch L, Hou C, Slater D, Vaccaro C, Watson D, Zackai EH, Billheimer J, Hakonarson H. A novel MBTPS2 variant associated with BRESHECK syndrome impairs sterol-regulated transcription and the endoplasmic reticulum stress response. Am J Med Genet A. 2022 Feb;188(2):463-472. PMID: 34655156

2021

Clark HH, Ballester L, Whitworth HB, Raffini L, Witmer C. Prevention of Recurrent Thrombotic Events in Children with Central Venous Catheter-Associated Venous Thrombosis. Blood. 2021 Nov 2:blood.2021013453. doi: 10.1182/blood.2021013453. Epub ahead of print. PMID: 34727184.

Strong A, March ME, Cardinale CJ, Kim SE, Merves J, Whitworth H, Raffini L, Larosa C, Copelovitch L, Hou C, Slater D, Vaccaro C, Watson D, Zackai EH, Billheimer J, Hakonarson H. A novel MBTPS2 variant associated with BRESHECK syndrome impairs sterol-regulated transcription and the endoplasmic reticulum stress response. Am J Med Genet A. 2021 Oct 15. doi: 10.1002/ajmg.a.62537. Epub ahead of print. PMID: 34655156.

Whitworth HB, Sartain SE, Kumar R, Armstrong K, Ballester L, Betensky M, Cohen C, Diaz R, Diorio C, Goldenberg NA, Jaffray J, Keegan J, Malone K, Randolph A, Rifkin-Zenenberg S, Leung WS, Sochet AA, Srivaths L, Zia A, Raffini L. Rate of thrombosis in children and adolescents hospitalized with COVID-19 or MIS-C. Blood. 2021;138(2):190-198. doi:10.1182/blood.2020010218. PMID: 33895804; PMCID: PMC8079262.

Neese JM, Yum S, Matesanz S, Raffini LJ, Whitworth HB, Loomes KM, Mayer OH, Alcamo AM. Intracranial hemorrhage secondary to vitamin K deficiency in X-linked myotubular myopathy. Neuromuscul Disord. 2021 Jul;31(7):651-655. doi: 10.1016/j.nmd.2021.04.009. Epub 2021 May 11. PMID: 34120822.

2019

Doshi, BS, Rogers, RS, Whitworth, HB, Stabnick, EA, Britton, J, Butler, RB, Obstfeld, AE, Witmer, CM. Utility of repeat testing in the evaluation for von Willebrand disease in pediatric patients. J Thromb Haemost. 2019; 17: 1838– 1847. PMID: 31350816

Ta HQ, Whitworth H, Yin Y, Conaway M, Frierson H, Campbell MJ, Raj G, Gioeli D. Discovery of a novel long noncoding RNA overlapping the LCK gene that regulates prostate cancer cell growth. Mol Cancer. 2019;18(113):1-15. PMID: 31253147

2018

Candy V, Whitworth H, Grabell J, Thibeault L, Harpell L, Bowman M, Good D, Hopman WM, Sidonio RF, James PD. A decreased and less sustained desmopressin response in hemophilia A carriers contributes to bleeding. Blood Advances. 2018; 2(20), 2629-2636. PMID: 30327371

2012

Whitworth H, Bhadel S, Ivey M, Conaway M, Spencer A, Hernan R, Holemon H, Gioeli D. Identification of kinases regulating prostate cancer cell growth using an RNAi phenotypic screen. PLoS ONE. 2012;7(6):e38950. PMID: 22761715

Posters and Presentations

2022

Whitworth, H, Hubbard R, Leonard CE, Witmer C, Raffini L. “High rate of recurrent thrombosis in children with unprovoked venous thromboembolism” Oral presentation at the International Society on Thrombosis and Haemostasis Congress; London, England, U.K. July 2022.

Whitworth, H, Hubbard R, Leonard CE, Witmer C, Raffini L. “Rate of recurrent venous thromboembolism in infants with unprovoked venous thromboembolism” Poster presentation at the International Society on Thrombosis and Haemostasis Congress; London, England, U.K. July 2022.

2021

Whitworth, H “Coagulopathy in children with COVID: When to start anticoagulation” Invited lecture to the Al-Qassimi Women’s and Children’s Hospital International Pediatric Conference; Sharjah, United Arab Emirates (October 2021)

Whitworth, H “Thrombosis in children and adolescents hospitalized with SARS-CoV-2 related illness” Children’s Hospital of Philadelphia Department of Pediatrics Grand Rounds; Philadelphia, PA (June 2021)

Whitworth, H “Thrombosis in children and adolescents hospitalized with SARS-CoV-2 related illness” Oral presentation at Children’s Hospital of Philadelphia Division of Hematology Research Seminar; Philadelphia, PA (April 2021)

2018

Doshi BS, Rogers RS, Whitworth H, Stabnick E, Britton J, Butler R, Witmer CM. “Utility of Repeat Testing in the Evaluation for von Willebrand Disease in Pediatric Patients” Oral presentation by Dr. Doshi at the American Society of Hematology 60th Annual Meeting and Exposition; San Diego, CA (December 2018)

Invited Lectures

2021

Whitworth, H “Coagulopathy in children with COVID: When to start anticoagulation” Invited speaker to the Al-Qassimi Women’s and Children’s Hospital International Pediatric Conference; Sharjah, United Arab Emirates (October 2021)

 

Awards and Honors

2022, International Society of Thrombosis and Haemostasis Early Career Travel Award
2020, NIH/NHLBI T32 Training Grant in Hemostasis and Thrombosis, University of Pennsylvania/Children’s Hospital of Philadelphia
2020, Hematology Fellows Consortium
2016, Cum Laude, Emory University School of Medicine
2015, Alpha Omega Alpha Honor Medical Society
2012, Segal AmeriCorps Education Award
2011, University of Virginia Distinguished Majors Program, Awarded a degree with High Distinction
2011, Harrison Undergraduate Research Award, University of Virginia

Leadership and Memberships

Memberships in Professional Organizations

2021-present, American Society of Pediatric Hematology/Oncology
2020-present, American Society of Hematology
2020-present, Hemostasis and Thrombosis Research Society
2020-present, International Society on Thrombosis and Haemostasis
 - 2020-present, Pediatric/Neonatal Thrombosis and Hemostasis subcommittee
2019-present, Children’s Oncology Group