Serena Wu, MD, FACOG

female silhouette icon
Serena Wu, MD, FACOG, is a maternal-fetal medicine specialist in the Richard D. Wood Jr. Center for Fetal Diagnosis & Treatment at Children's Hospital of Philadelphia.

Areas of Expertise: Maternal outcomes after fetal interventions, Obstetrical management of pregnancies impacted with birth defects, Prenatal diagnosis and fetal therapy, Perinatal palliative care, Pregnancy and perinatal loss, Maternal outcomes and the "fourth trimester", Ethical decision making, counseling and informed consent surrounding therapies and perinatal care of the maternal-fetal dyad
Locations: Main Hospital
Appointments and Referrals (800-IN UTERO): 800-468-8376

Education and Training

Medical School

MD - Warren Alpert Medical School of Brown University, Providence, RI


Obstetrics and Gynecology - University of Chicago, Chicago, IL


Fetal Therapy and Biology Research Fellowship - Children’s Hospital of Philadelphia, Philadelphia, PA
Maternal-Fetal Medicine - University of Chicago, Chicago, IL
Clinical Research Training Program & Essentials of Patient-Oriented Research - University of Chicago, Chicago, IL

Board Certification

Maternal-Fetal Medicine – American Board of Obstetrics and Gynecology
Nuchal Translucency Quality Review (NTQR)
Obstetrics and Gynecology – American Board of Obstetrics and Gynecology

Titles and Academic Titles

Maternal-Fetal Medicine Specialist

Assistant Professor of Clinical Obstetrics and Gynecology in Surgery

Departments and Services




Macedonia C, Sullenberger R, Wu S, etc. “Cell-Free DNA: 10 Things Every Health Care Provider Should Know. The Journal of Lancaster General Hospital, Lancaster General Hospital. Summer 2016: Vol 11, No 2.


Huberty JL, Coleman J, Rolfsmeyer K, Wu S. “A qualitative study exploring women's beliefs about physical activity after stillbirth.” BMC Pregnancy Childbirth. 2014 Jan 17;14:26.


French VA, Davis JS, Sayles HS, Wu S. “Contraception and Fertility Awareness Among Women With Solid Organ Transplants.” Obstet Gynecol 2012:122(4);809-14

Seet EL, Kay H, Wu S, Terplan M. “Placenta accreta: depth of invasion and neonatal outcomes.” J Matern Fetal Neonatal Med. 2012 Oct;25(10):2042-5.


Wu S. “Never an Ordinary Day: Struggles of a Perinatologist”. Atrium, Northwestern University Bioethics Journal 2009: Issue 7:26-27.

Wu S and Johnson MP. “Fetal Lower Urinary Tract Obstruction.” Clin Perinatol 2009:Jun;36(2):377-90.


Wu S and Stephenson MD. “Obstetrical Antiphospholipid Syndrome.” Sem Reprod Med 2006:24(1);40-53.


Wu S, Kocherginsky M, Hibbard J. “Abnormal Placentation: Twenty Year Analysis.” Amer J Obstet Gynecol 2005:192(5);1458-1461.

Awards and Honors

2017, Outstanding Advanced Practice Provider/Physician Team, Penn Medicine/Lancaster General Health
2007, T32 NIH Training Program in Fetal Biology and Therapy
2004, First Place, Chicago Gynecological Society Resident paper competition. Abnormal Placentation: Where are we now? Analysis of the last twenty years.
1993, Rhode Island Collegiate Women Athlete of the Year
1992, Brown University Summer Research Fellowship Award
1989, Gilbane Scholar-Athlete Scholarship

Leadership and Memberships

Memberships in Professional Organizations

American College of Obstetricians and Gynecologists, Fellow
PA Medical Society
Society of Maternal-Fetal Medicine


Share of Lancaster, Board of Directors