Yael P. Mossé, MD , an attending physician at Children's Hospital of Philadelphia’s (CHOP) Cancer Center, was recently profiled by the Conquer Cancer Foundation of the American Society of Clinical Oncology. Mossé has received Conquer Cancer grants that have fueled her research into the cause of and treatment for neuroblastoma.
Mossé has investigated the genetics of neuroblastoma patients. In 2003, as a fellow at CHOP, she was granted a Conquer Cancer Young Investigator Award to explore her idea for one year. A Conquer Cancer Career Development Award followed in 2004, providing three more years of research funding.
Mossé discovered mutations of a gene called ALK that tells the human body how to make certain proteins. She has been conducting clinical trials for a drugs developed specifically to turn off the ALK gene. Additionally, she is working on anticipating and preventing resistance to the current therapy.