Research News from CHOP


Children’s Hospital of Philadelphia Features Innovative Concussion Research at the UAE’s Ministry of Health and Prevention’s Arab Health 2021 Conference
As part of a longstanding partnership with the United Arab Emirates (UAE) Ministry of Health and Prevention (MOHAP), CHOP showcased innovative diagnostic tools to assess head trauma in real time as an athlete is competing and experiencing injury in the MOHAP booth at the annual Arab Health Exhibition and Congress.

Cell Phone Use While Driving May Be Tied to Other Risky Road Behaviors in Young Adults
Pattern of risky driving practices associated with impulsivity, including speeding and running red lights.
CHOP Researchers Use Big Data to Assess Seizure Burden and Improve Outcomes in Pediatric Epilepsy Patients
CHOP is the only center to capture standardized clinical data from ongoing patient care.

CHOP Researchers Develop Proof-of-Concept Treatment that Elevates Both Adult and Fetal Hemoglobin
CHOP researchers have developed a proof-of-concept treatment for blood disorders like sickle cell disease that elevates both fetal and adult hemoglobin.
CHOP Researchers Create Search Engine Linking Diseases and Observable Traits
The new search engine, called PhenCards, can help researchers, clinicians, and genetic counselors make more informed clinical decisions.
Researchers Show How Mitochondrial Function Influences Schizophrenia Status in Patients with Genetic Disorder
New findings set stage for future targeted therapies for patients with 22q11.2 deletion syndrome, who are 25 times more likely to develop schizophrenia.
Researchers Discover New Genetic Variants Responsible for Neurodevelopmental Disorders
A dozen patients have clinical features linked to the genetic variants, and preclinical models reveal more about how they affect normal function.
Researchers Find Association Between Financial Strain Due to COVID-19 and Depression
CHOP researchers found a link between depressive symptoms and pandemic-related income loss and financial strain, independent of anxiety.
Applying New Framework Improves Big Data Analysis for Pediatric and Adult Epilepsies
When applying new terminology to existing data through computational methods, researchers increased the number of descriptive terms five-fold, improving diagnostic capabilities.

CHOP Researchers Discover New Disease that Prevents Formation of Antibodies
CHOP researchers discovered a new condition, which they named PU.MA, and treated a patient with a bone marrow donation from the patient’s older brother.