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Children’s Hospital of Philadelphia Successfully Separates Conjoined Twin Boys
After nearly a year at Children’s Hospital of Philadelphia (CHOP), conjoined twins Amari and Javar Ruffin were successfully separated by CHOP surgeons on August 21, 2024.
CHOP Evaluates Strategies in the Pediatric Intensive Care Unit (PICU) to Enhance Communication and Ensure Equitable Participation in Research
In a new retrospective cohort study, researchers at Children’s Hospital of Philadelphia (CHOP) discuss disparities in race and ethnicity when enrolling families to participate in research conducted in its Pediatric Intensive Care Unit (PICU).
New Study Shows AML Ages Immune Cells, Leading to Poor Treatment Response
A new study has found that acute myeloid leukemia (AML) ages and exhausts immune cells, impairing their ability to fight off cancer.
Children’s Hospital of Philadelphia Appoints New Chief of Critical Care Medicine
Robert Sutton, MD, will fulfill leadership role within the Department of Anesthesiology and Critical Care Medicine.
First Approved CAR T-Cell Therapy Shows Continued Benefits Five Years Later
New data on show CAR T-cell therapy leads to durable remission and long-term survival in children and young adults with relapsed or refractory B-ALL.
CHOP Researchers Develop Allogeneic CART for Relapsed or Refractory T-ALL Using Base Editing
CHOP researchers have tested and developed an “off-the-shelf” chimeric antigen receptor T-cell (CART) using base editing.
CHOP Brings Together Experts to Discuss Precision Medicine in Pediatric Cancer Care
More than 250 experts gathered in Philadelphia and virtually to discuss the latest scientific advancements and breakthroughs in pediatric precision medicine oncology.
CHOP-Led Study Finds Bortezomib Improves Survival in Children with Newly Diagnosed T-Cell Lymphoblastic Lymphoma
In a COG trial, CHOP researchers found adding bortezomib to chemotherapy significantly improved overall survival in children and young adults with newly diagnosed T-cell lymphoblastic lymphoma (T-LL).

CHOP Announces Dollar-For-Dollar Matching Gift Campaign, Will Fund New Discoveries to Transform Personalized Pediatric Surgical Care
Inspired by the separation of conjoined twins Addy and Lily Altobelli, an anonymous donor will match up to $2 million.
CHOP/Penn Study Shows CAR-T Cells Remain Active a Decade After Infusion
A new study in Nature has documented the longest persistence of CAR T cell therapy to date.