Driving Directions to CHOP’s Philadelphia Campus

Travel Advisories

Please allow for extra travel time to your appointments due to traffic congestion caused by multiple construction projects around CHOP and the Hospital of the University of Pennsylvania, including the partial closure of the Wood Garage.

The main entrance to Children's Hospital of Philadelphia is located at 3401 Civic Center Blvd., Philadelphia, PA 19104.

This page offers detailed driving directions to the Main Hospital and the rest of our Philadelphia Campus. 

For more transportation information, please see our parking informationpublic transportation options and and maps of our Philadelphia Campus.

From Northeastern Areas

From I-95 South, follow Exit 22 for I-676 West (also known as the Vine Street Expressway). Follow I-676 to exit for I-76 East, International Airport. Follow I-76 East to exit 346A for South Street. Stay in the right lane, then turn right onto South Street. At the next light, turn left onto Convention Avenue. At the second light, bear right and continue on Convention Avenue. At the next light, you are directly across the street from the entrance to CHOP's Main Hospital Parking A. For appointments at the Main Hospital, Buerger Center, Wood Center or Seashore House, make a left onto Civic Center Boulevard. At the second traffic light, turn right at Driveway C for the Main Hospital, Wood Center and Seashore House, or turn left at Driveway B for the Buerger Center. 

From the West

Take the Pennsylvania Turnpike to Exit 326 (old exit 24), Valley Forge. Take I-76 East to exit 346A for South Street. Stay in the right lane, then turn right onto South Street. At the next light, turn left onto Convention Avenue. At the second light, bear right and continue on Convention Avenue. At the next light, you are directly across the street from the entrance to CHOP's Main Hospital Parking A. For appointments at the Main Hospital, Buerger Center, Wood Center or Seashore House, make a left onto Civic Center Boulevard. At the second traffic light, turn right at Driveway C for the Main Hospital, Wood Center and Seashore House, or turn left at Driveway B for the Buerger Center. 

From the North

Take I-476 South to Exit 20 (old exit 25A), Mid-County. After toll, continue south on I-476 to Exit 16A for I-76 East, Schuylkill Expressway-Philadelphia. Follow I-76 East to exit 346A for South Street. Stay in the right lane, then turn right onto South Street. At the next light, turn left onto Convention Avenue. At the second light, bear right and continue on Convention Avenue. At the next light, you are directly across the street from the entrance to CHOP's Main Hospital Parking A. For appointments at the Main Hospital, Buerger Center, Wood Center or Seashore House, make a left onto Civic Center Boulevard. At the second traffic light, turn right at Driveway C for the Main Hospital, Wood Center and Seashore House, or turn left at Driveway B for the Buerger Center. 

From the South

Take I-95 North to Exit 13, I-76 West - Valley Forge. Merge right to exit for Center City. Cross the bridge and turn left at the light to I-76 West. Take exit 346A for South Street. Stay in the left lane and turn left onto South Street. At the next light, turn left onto Convention Avenue. At the second light, bear right and continue on Convention Avenue. At the next light, you are directly across the street from the entrance to CHOP's Main Hospital Parking A. For appointments at the Main Hospital, Buerger Center, Wood Center or Seashore House, make a left onto Civic Center Boulevard. At the second traffic light, turn right at Driveway C for the Main Hospital, Wood Center and Seashore House, or turn left at Driveway B for the Buerger Center. 

From New Jersey

Take the New Jersey Turnpike to Exit 3, then the Black Horse Pike (Rte. 168 North) for one mile to I-295 South. Go one mile to Exit 26, I-76 West to the Walt Whitman Bridge. Cross the Bridge onto I-76 West (Schuylkill Expressway) to exit 346A for South Street. Stay in the left lane and turn left onto South Street. At the next light, turn left onto Convention Avenue. At the second light, bear right and continue on Convention Avenue. At the next light, you are directly across the street from the entrance to CHOP's Main Hospital Parking A. For appointments at the Main Hospital, Buerger Center, Wood Center or Seashore House, make a left onto Civic Center Boulevard. At the second traffic light, turn right at Driveway C for the Main Hospital, Wood Center and Seashore House, or turn left at Driveway B for the Buerger Center. 

Alternate route from New Jersey and points East

Take the Benjamin Franklin Bridge to 676 West (Vine St. Expressway). Follow I-676 to exit for I-76 East, International Airport. Take I-76 East to exit 346A for South Street. Stay in the right lane, then turn right onto South Street. At the next light, turn left onto Convention Avenue. At the second light, bear right and continue on Convention Avenue. At the next light, you are directly across the street from the entrance to CHOP's Main Hospital Parking A. For appointments at the Main Hospital, Buerger Center, Wood Center or Seashore House, make a left onto Civic Center Boulevard. At the second traffic light, turn right at Driveway C for the Main Hospital, Wood Center and Seashore House, or turn left at Driveway B for the Buerger Center. 

From Montgomery County

Take I-76 East to exit 346A for South Street. Stay in the right lane, then turn right onto South Street. At the next light, turn left onto Convention Avenue. At the second light, bear right and continue on Convention Avenue. At the next light, you are directly across the street from the entrance to CHOP's Main Hospital Parking A. For appointments at the Main Hospital, Buerger Center, Wood Center or Seashore House, make a left onto Civic Center Boulevard. At the second traffic light, turn right at Driveway C for the Main Hospital, Wood Center and Seashore House, or turn left for the Buerger Center. 

From West Philadelphia

Travel east on Chestnut or Spruce Street to 34th St. Turn right onto 34th St., which becomes Civic Center Boulevard. Continue on Civic Center Boulevard as it curves right around the Hospital. After the curve, at the second traffic light, turn right at Driveway C for appointments at the Main Hospital, Wood Center and Seashore House, or turn left at Driveway B for the Buerger Center. 

From Center City

Travel west on Market or Walnut Street to 34th St. Turn left at 34th Street, which becomes Civic Center Boulevard. Continue on Civic Center Boulevard as it curves right around the Hospital. After the curve, at the second traffic light, turn right at Driveway C for appointments at the Main Hospital, Wood Center and Seashore House, or turn left at Driveway B for the Buerger Center. 

From Northeast Philadelphia

Take Roosevelt Boulevard to I-76 East. Take I-76 East to exit 346A for South Street. Stay in the right lane, then turn right onto South Street. At the next light, turn left onto Convention Avenue. At the second light, bear right and continue on Convention Avenue. At the next light, you are directly across the street from the entrance to CHOP's Main Hospital Parking A. For appointments at the Main Hospital, Buerger Center, Wood Center or Seashore House, make a left onto Civic Center Boulevard. At the second traffic light, turn right at Driveway C for the Main Hospital, Wood Center and Seashore House, or turn left at Driveway B for the Buerger Center. 


Next Steps

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