Most Recent Articles
Two Generations. Two Buildings. Always Expert Care: Parkes Family HI Story
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Two generations of the Parkes family have come to Children’s Hospital of Philadelphia for treatment for hyperinsulinism (HI). They’ve seen and experienced breakthroughs in HI care firsthand.
Trailblazing HI Treatments Begin at CHOP
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Leaders of the HI Center at CHOP remember two decades of advancements in care for children with HI.
Missing or Medicated Pancreas Means Missing Key Enzymes
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Children with congenital hyperinsulinism (HI) may be at risk for exocrine pancreatic insufficiency, which affects the ability of the pancreas to function properly.
CHOP’s HI Team Leading Research Nationally
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Our HI team has been busy continuing to pave the way to improve the diagnosis, treatment and outcomes for children with hyperinsulinism through discovery and innovation.
The Ups and Downs of Living with HI
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Patients share their experiences of growing up with HI during the 2016 Congenital Hyperinsulinism Family Conference in Philadelphia.
Dr. Stanley’s Pioneering Career Recognized
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Charles A. Stanley, MD, received the Judson J. Van Wyk Prize, the most prestigious award given by the Pediatric Endocrine Society.
CHOP Article Highlights Three Novel Cases of HNF HI
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Read a brief description about three novel cases of HI caused by mutations in the MODY (maturity-onset diabetes of youth) genes, HNF1A and HNF4A. Two of the cases are the first to report HNF1A mutations as a cause of congenital HI.
HI Center Founder Charles Stanley, MD, Receives Lifetime Achievement Award
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Charles Stanley, MD, the founding director of the Congenital Hyperinsulinism Center at CHOP, was presented with a lifetime achievement award by Congenital Hyperinsulinism International (CHI) at the Sugar Soiree in New York City in November.
Near-total Pancreatectomy Means Eventual Diabetes
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CHOP researchers, led by endocrinologists Katherine Lord, MD, and Diva D. De León-Crutchlow, MD, MSCE, studied the outcomes of 121 patients who had undergone a pancreatectomy. They found that 36 percent later developed diabetes.
Sometimes, HI Can Fade Away
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At 4 years old, Leila is proof that in some children hyperinsulinism (HI) is transient: She outgrew it.