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CHOP Biobank: Unlocking the Secrets to Childhood Health and Disease
Imagine a world where we can identify disease markers specific to pediatric illnesses; find patterns between medical history, cellular findings, and diseases; and develop new treatments and diagnostic tools. That's the potential power of the Children's Hospital of Philadelphia Biobank.

Children’s Hospital of Philadelphia Researchers Secure Funding to Explore Progesterone Therapy Response Mechanisms in Fetuses with Hypoplastic Left Heart Syndrome (HLHS)
A research team in the Cardiac Center at Children’s Hospital of Philadelphia (CHOP) in collaboration with Boston Children’s Hospital and the Perelman School of Medicine at the University of Pennsylvania was awarded a $660,000 grant over three years by Additional Ventures through its Single Ventricle Research Fund to accelerate research and develop therapies for fetuses with hypoplastic left heart syndrome (HLHS).
Gregory Davis Named Chair of CHOP’s Board of Trustees
Gregory Davis, President and Chief Investment Officer of The Vanguard Group, has been named Chair of CHOP’s Board of Trustees, effective July 1, 2025.
Jason Armstrong Joins CHOP’s Board of Trustees
Jason Armstrong, Chief Financial Officer for Comcast Corporation, has joined CHOP’s Board of Trustees, effective July 1, 2025.
Children’s Hospital of Philadelphia Researchers Find Children with IBD Have Hidden Risk to Bone Health
A new study from researchers at Children’s Hospital of Philadelphia (CHOP) found that children and young adults living with inflammatory bowel disease (IBD may face a hidden threat – weakened bones. Researchers showed that a significant number of young patients with IBD have low bone mineral density (BMD), putting them at a higher risk for fractures and long-term bone complications.
"Just the Vax" Trivia Corner
What was the first vaccine to prevent a known cause of cancer? Find out.
Feature Article: 9,000 Reasons for Routine Childhood Hepatitis B Vaccination
Find out why the birth dose hepatitis B vaccine recommendation is important and see how many other countries also recommend this approach for protecting their citizens from hepatitis B.
Vaccine News & Notes — July 2025
Find info about thimerosal in influenza vaccines and get an update on the U.S. measles outbreaks.
New Tool Developed by Children’s Hospital of Philadelphia Researchers Decodes Complex DNA Methylation
Researchers in the Center for Computational and Genomic Medicine at Children’s Hospital of Philadelphia (CHOP) developed a new tool called the Methylation Screening Array (MSA) to better understand how changes in DNA methylation-mediated regulation of genes, rather than changes in the genes themselves, affect complex human traits like aging and disease risk. This is the first data set to dissect the two forms of DNA methylation---5-methylcytosine and 5-hydroxymethylcytosine---to associate characteristics such as cell composition, gene regulatory mechanism, and epigenetic age in diverse human cell lines and tissues.

ChristianaCare and Children's Hospital of Philadelphia Agree to Join Forces, Expand Access to World-Class Pediatric Care in Delaware
ChristianaCare and Children’s Hospital of Philadelphia announce a new strategic affiliation to expand access to world-class pediatric care in Delaware and surrounding communities.