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Assessing Optically Pumped Magnetoencephalography (MEG)

Assessing Optically Pumped Magnetoencephalography (MEG)

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This study is now recruiting. Learn more about enrolling here.

Description

The goal for this study is to compare performance between a conventional helium based “Cryo_MEG” (magnetoencephalography) system and an investigational optically pumped (‘OP_MEG’) MEG system using brain recordings from typically developing adults. MEG (magnetoencephalography) is a safe, non-invasive brain imaging method used in many forms of research as well as clinical care. MEG is measured by safely wearing a helmet filled with MEG sensors. During the MEG scan, you will be asked to look at a screen, listen to some tones, and push a button. OPM (Optically Pumped Magnetometry), is a brain imaging method that is also worn as a helmet and acquires MEG recording data but differs from conventional “cryo-MEG” because OPM sensors can be positioned closer to the head. This may present an opportunity for better measurement of underlying brain activity.

Eligibility and criteria


IRB Number:
22-020407
Eligible age range:
10 years - 45 years
Clinical trial phase:
Phase I
Official title:
A Wearable High-Density MEG system with uOP_MEGs

What to expect

The study will involve one visit to The Children’s Hospital of Philadelphia. During the visit, participants will undergo a cryo-MEG scan as well as an OP_MEG scan, where four experiments will be performed on each of the two MEG modalities for a total of 1.5 hours. This is followed by a brain MRI scan as the final part of the visit. 
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