Palbociclib, Irinotecan, and Temozolomide in Ewing Sarcoma

Palbociclib, Irinotecan, and Temozolomide in Ewing Sarcoma

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This study is no longer recruiting.

Description

The purpose of the Phase 2 portion of this study is to evaluate the safety and efficacy of the study drug called palbociclib when given in combination with two other drugs (temozolomide and irinotecan) in patients with Ewing sarcoma and when given in combination with topotecan and cyclophosphamide in patients with neuroblastoma.

Eligibility and criteria
IRB Number:
19-016357
Eligible age range:
2 years - 20 years
Clinical trial phase:
Phase II
Official title:
Phase 1/2 Study to Evaluate Palbociclib (Ibrance) in Combination with Irinotecan and Temozolomide and/or in Combination with Topotecan and Cyclophosphamide in Pediatric Patients with Recurrent or Refractory Solid Tumors (ADVL1921)

Related specialties

Related conditions
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