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VOCAL Trial

VOCAL Trial

Contact

If you are interested in participating in the study or want to learn more, please contact: Contact us
This study is now recruiting. Learn more about enrolling here.

Description

This is a study to measure the effectiveness of the medication voclosporin compared to placebo in adolescent patients with active lupus nephritis. Volcosporin is an outpatient, oral medication.

Eligibility and criteria


IRB Number:
23-021424
Eligible age range:
12 years - 18 years
Clinical trial phase:
Phase III
Official title:
A Double-Blind, Placebo-Controlled, Dose Escalation Study to Assess the Efficacy, Safety and Pharmacokinetics of Voclosporin in Adolescents with Lupus Nephritis

What to expect

Along with taking voclosporin, participants will also:
  • Provide blood and urine samples
  • Complete physical exams
  • Complete an ECG (electrocardiogram) 
  • Complete questionnaires and a disease activity assessment
  • Take MMF (mycophenolate mofetil)/oral corticosteroids 
  • Have methylprednisolone administration
  • Some people will take a placebo
  • Have medical record review(s)
Participation will last for 32 weeks and will involve 14 study visits.
Smiling CHOP patient holding shopping bag

We need families like you

Your time and participation make a difference in supporting the work of the Research Institute and children in our community. Learn more about opportunities to participate in our research.

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