Breakthrough Report

An ongoing collection of our most inspiring stories

We saw improvement right away. When I saw the images after her treatment, I gasped.

Making Tools to Deliver Disease Cures

CHOP and its partners built a new clinical manufacturing facility to produce biotechnology tools that deliver cell and gene therapy for difficult-to-treat diseases.

Better Understanding of Autism in Girls

For every four boys diagnosed with autism, only one girl is diagnosed with the condition. CEO Madeline Bell explores the autism gender gap in her Breaking Through podcast.

Digging into Data to Drive Breakthroughs

The new Center for Computational and Genomic Medicine, led by Yi Xing, PhD, will analyze large collections of biological data to make discoveries to improve children’s health.

Tackling Concussion

Lessons learned from the pros and CHOP research will inform future prevention, diagnosis and treatment.

Pioneers in Hyperinsulinism

CHOP has been on the forefront of understanding and treating this rare condition that creates dangerously low blood sugar.

Meet the "Master" Endocrinologist

Michael A. Levine, MD, cited as “world authority on the genetics of parathyroid disease,” was recognized by his peers in the American College of Endocrinology.

Fetal Radiologist Honored for Contributions

Fetal imaging expert Beverly G. Coleman, MD, received the Distinguished Service Award from the Society of Radiologists.

Neurosurgeon Hailed as Healthcare Hero

Phillip (Jay) Storm, MD, who launched the Children’s Brain Tumor Tissue Consortium in 2009, was honored for sparking shared research among institutions worldwide.

CHOP’s Innovation Gains National Recognition

Children’s Hospital was named one of the 20 most innovative pediatric hospitals by Parents magazine, which praised our novel treatment for relapsed leukemia.


A Diagnostic Odyssey

Words can’t capture what it means to see Elijah doing so well.

Treating the Whole Child in One Place

Putting behavioral health services in primary care offices makes it easier for families to get their children the treatment they need.

See Advocacy in Action

Because every child deserves access to healthcare.

New Hospital on the Horizon

CHOP will build a freestanding pediatric hospital in King of Prussia, bringing our world-class inpatient care closer to suburban families.

More Breakthroughs Ahead!

Care for children with chronic lung disease, airway disorders and mitochondrial disease get a boost as Frontier Programs.

Innovative Treatment Replaces Major Surgery

Mac, 17, was able to receive a newly developed finger-sized device to fix a leaky heart valve, saving him from an open-heart surgery.

Honoring a Cutting-edge Cancer Investigator

The National Cancer Institute recognized the career-long dedication of John Maris, MD, to solving the mysteries of neuroblastoma.

Rare Impact on Rare Conditions

Robert Campbell, MD, received a lifetime achievement award for his groundbreaking work helping children with thoracic insufficiency syndrome.

Immunology’s Highest Award

The Immune Deficiency Foundation recognized Kathleen Sullivan, MD, PhD, with the Boyle Scientific Achievement Award.

Gold Medal Career

Vaccine expert Paul Offit, MD, received the 2018 Albert B. Sabin Gold Medal in recognition of his decades of research and advocacy.

Checking in on Formerly Conjoined Twins

Abby and Erin Delaney are thriving months after separation surgery at Children’s Hospital of Philadelphia.

Families Key to Breakthroughs

State-of-the-art new buildings are great, but breakthroughs happen because families are willing to allow their children to participate in research.

PICU’s 50-Year Anniversary

Fifty years ago, CHOP established the nation’s first pediatric intensive care unit for the sickest children. Those six beds are now a 55-bed unit caring for 3,000-plus children a year.

A Big Breakthrough for Our Tiniest Patients

We’ve reimagined how to improve outcomes for babies born too early.

Making Ben Proud

Douglas Wallace, PhD, is considered the founder of mitochondrial genetics. His groundbreaking research at CHOP earned him two prestigious international awards in 2017.

Awe-inspiring Careers

The American Academy of Pediatrics honored three CHOP doctors with lifetime achievement awards in 2017.

Winston Voted into Academy

The accident-prevention research of Flaura Koplin Winston, MD, PhD, has saved countless lives and earned her election to the National Academy of Medicine.

20 Years of Sharing

Orthopaedic surgeon David A. Spiegel, MD, was recognized for his 20-plus years of humanitarian work in underserved regions around the world.

Historic Campaign to Fuel Tomorrow’s Breakthroughs

CHOP’s ambitious fundraising campaign, For Tomorrow’s Breakthroughs, reflects and enables the Hospital’s relentless drive to improve children’s health.