Cellular Therapy and Transplant Section News

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Researchers Publish Final Results of Key Clinical Trial for Gene Therapy for Sickle Cell Disease

Apr 24, 2024

In a landmark study, an international consortium led by researchers at CHOP published the final results of a key clinical trial of the gene therapy CASGEVY for the treatment of sickle cell disease.

CHOP Treats 500th CAR T Patient

Jul 17, 2023

CHOP has treated its 500th patient with CAR T-cell immunotherapy, a “living drug” that harnesses the power of a patient’s own immune system to fight cancer.

CHOP Will Be Provider in Independence Blue Cross’s Gene Therapy Network

Jan 26, 2023

CHOP will be a provider in Independence Blue Cross’s new Advanced Network for Gene-Based Therapeutics, effective March 1, 2023.

CHOP Researchers Develop Tool that Reduces Errors in Stem Cell Transplant Reporting

Jan 23, 2023

CHOP researchers have developed a custom-built application to automate determination of engraftment, a key outcome after hematopoietic stem cell transplant.

Two CHOP Researchers Named 2022 STAT Wunderkinds

Dec 1, 2022

Two researchers from Children’s Hospital of Philadelphia (CHOP) were recently selected by the health and science news outlet STAT as 2022 Wunderkinds, an award that celebrates the next generation of scientific superstars who are making significant contributions to biomedical research.

CHOP Study Finds CAR T-Cell Therapy Improves Survival Regardless of Socioeconomic Status

Nov 10, 2022

Researchers from Children’s Hospital of Philadelphia (CHOP) have found that economically disadvantaged children treated with CAR T-cell therapy for relapsed/refractory acute lymphoblastic leukemia (ALL) fair just as well as children from more socioeconomically advantaged backgrounds.

FDA Approves First Potentially Curative Gene Therapy for Beta Thalassemia

Aug 24, 2022

A leading study site for nearly a decade, CHOP will be part of a network of treatment centers in the country offering the therapy to patients who require regular blood transfusions.

First Approved CAR T-Cell Therapy Shows Continued Benefits Five Years Later

Jun 16, 2022

New data on show CAR T-cell therapy leads to durable remission and long-term survival in children and young adults with relapsed or refractory B-ALL.

New Data Show Benefits of CRISPR-edited Gene Therapy for Blood Disorders in a Larger Patient Group with Longer-Term Follow-Up

Jun 14, 2022

A group of researchers that includes CHOP presented new data on CRISPR-edited gene therapy for blood disorders at an international meeting.

Penn Medicine and Children’s Hospital of Philadelphia Announce Partnership with Costa Rica for CAR T Cell Therapy

May 23, 2022

International collaboration aims to ensure more equitable access to transformative personalized cancer therapy.

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