A collaborative team of researchers from Children’s Hospital of Philadelphia (CHOP) found that hematopoietic stem cell transplantation is a highly effective method for treating patients with monogenic inflammatory bowel disease (IBD), a more severe form of the illness usually affecting younger patients.

Doctors Amanda Muir and Kate Hamilton share a common interest in using patient-derived organoids to study pediatric gastrointestinal (GI) diseases. In 2019, they established the Gastrointestinal Epithelium Modeling Program, a collaborative effort dedicated to accelerating discovery and innovation in the search for cures and prevention strategies for these diseases.

The 2024 Gut Cell Atlas (GCA) Convening highlighted the most recent research advances into understanding the biology of Crohn’s disease. Drs. Kate Hamilton and Tatiana Karakasheva represent the Children’s Hospital of Philadelphia Research Institute in this initiative, which aims to build a detailed catalog the cell types composing human small and large intestines, further our understanding of Crohn's disease, and identify pathways towards curative therapy and ultimately, prevention.

CHOP’s new Chief of the Division of Gastroenterology, Hepatology and Nutrition shares her vision for the department’s future.

Recently Children’s Hospital of Philadelphia (CHOP) hosted its annual Walk for Hope benefiting the Center for Pediatric Inflammatory Bowel Disease (IBD) at CHOP, raising more than $247,000 and sparking hope for a cure to IBD.

Children’s Hospital of Philadelphia (CHOP) has appointed Binita M. Kamath, MB BChir as Chief of the Division of Gastroenterology, Hepatology and Nutrition. Dr. Kamath has served for the last fifteen years as an attending physician in the Department of Gastroenterology, Hepatology and Nutrition at the Hospital for Sick Children (SickKids) in Ontario, Canada. She has been the interim Division Head at SickKids for the last 2 years.

The Esophageal and Airway Treatment Program at CHOP specializes in treating children with airway and esophageal conditions.  

The Martha Escoll Lubeck Feeding and Swallowing Center provides interdisciplinary care for children with a host of feeding and swallowing disorders. 

Amit A. Shah, MD, MSHP, shares why he choose to work with children with liver disease and what makes CHOP’s Pediatric Liver Center stand out. 

Gastroenterologists at CHOP are on a mission to unravel the mysteries of the microbiome and harness its potential to treat diseases.