CHOP hosts the 7th Annual Immune Dysregulation Symposium on April 30 for clinicians and researchers who care for patients with complex, multi-organ immune diseases.

Hemophagocytic lymphohistiocytosis (HLH) and macrophage activation syndrome (MAS) are overlapping hyperinflammatory syndromes that involve disorganization and malfunction of the immune system, leading to widespread inflammation and organ damage. The conditions can progress rapidly, making early identification and management key for preventing organ failure and death.

Breaking Through with Madeline Bell’s “Where We Are Now” series highlights CHOP doctors and researchers who are working to bring an end to the COVID-19 pandemic.

Findings could discover how disease-causing variations lead to a variety of autoimmune disorders.

A 4-year-old boy presented to the emergency room reporting 2 weeks of right knee pain, swelling, and limping.