Solid Tumor Program News

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Two CHOP Studies Find Role for ALT in Treatment-Resistant CNS Tumors

Apr 26, 2023

Two recent papers from CHOP cancer researchers have advanced the understanding of treatment-resistant pediatric central nervous system tumors.

Researchers Show Lorlatinib is Safe, Effective for Patients with High-Risk Neuroblastoma

Apr 3, 2023

CHOP researchers have shown that adenovirus proteins use a process called phase separation to coordinate production of viral progeny, which could have broad implications.

CHOP Researchers Show Liquid Biopsies Can Catch Disease Progression Early in High-Risk Neuroblastoma

Nov 14, 2022

CHOP researchers found that a series of “liquid biopsies” could less invasively and more accurately identify tumor changes in patients with high-risk neuroblastoma.

CHOP Researchers Join Global Team to Take on Solid Tumors in Children

Jun 16, 2022

Four CHOP researchers are part of a world-class research team that will receive $25 million to study solid tumors in children, funded by Cancer Grand Challenges.

CHOP Brings Together Experts to Discuss Precision Medicine in Pediatric Cancer Care

Mar 18, 2022

More than 250 experts gathered in Philadelphia and virtually to discuss the latest scientific advancements and breakthroughs in pediatric precision medicine oncology.

CHOP Researchers Refine Experimental Prodrug Treatment of High-Risk Neuroblastoma

Mar 14, 2022

CHOP researchers have shown that linking a tumor-killing prodrug to a macromolecular carrier of the Poloxamer family improves retention of the drug in treatment-resistant neuroblastoma tumors.

CHOP Researchers Develop a New Class of CAR-T Cells that Target Previously Untargetable Cancer Drivers

Nov 3, 2021

CHOP researchers have developed a novel cancer therapy that targets proteins inside cancer cells that are essential for tumor growth and survival but have been historically impossible to reach.

CHOP Cancer Researchers Win 2021 AACR Team Science Award

Apr 9, 2021

The award was presented to the St. Baldrick’s Foundation-Stand Up 2 Cancer Pediatric Cancer Dream Team, co-led by CHOP, at the annual AACR conference.

CHOP Researchers Awarded Crazy 8 Grant from Alex’s Lemonade Stand Foundation

Mar 16, 2021

CHOP researchers will receive funds to discover a new drug that targets MYCN, a transcription factor involved in some pediatric cancers.

Yael Mossé, MD, Featured by the Conquer Cancer Foundation

Dec 7, 2020

The CHOP physician-researcher’s investigation into cause of and treatment for neuroblastoma has been supported by Conquer Cancer grants.

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