Marissa A. Brunetti, MD

female silhouette icon
Marissa A. Brunetti, MD, is a cardiac intensivist with the Division of Cardiac Critical Care Medicine at Children's Hospital of Philadelphia.

Locations: Main Hospital
Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

Education and Training

Medical School

MD - Jefferson Medical College, Philadelphia, PA


Pediatrics - Johns Hopkins Hospital, Baltimore, MD


Pediatric Critical Care Medicine - Johns Hopkins Hospital, Baltimore, MD
Pediatric Cardiology - Johns Hopkins Hospital, Baltimore, MD

Board Certification

Pediatric Cardiology – American Board of Pediatrics
Pediatric Critical Care Medicine – American Board of Pediatrics
Pediatrics – American Board of Pediatrics

Titles and Academic Titles

Associate Director of Simulation, Cardiac Center

Cardiac Intensivist

Assistant Professor of Clinical Anesthesiology and Critical Care, Perelman School of Medicine at the University of Pennsylvania

Departments and Services




Noje C, Bembea MM, Nelson McMillan KL, Brunetti MA, Bernier ML, Costabile PM, Klein BL, Duval-Arnould J, Hunt EA, Shaffner DH: A national survey on interhospital transport of children in cardiac arrest. Peds Crit Care Med 20(1): e30-e36, January 2019.


Smith AH, Anand V, Banerjee M, Bates KE, Brunetti MA, Cooper DS, Lehrich J, Mistry KP, Pasquali SK, Shin AY, Tabbutt S, Gaies M: Variation in case-mix adjusted unplanned pediatric cardiac ICU readmission rates. Crit Care Med 46(12): e1175-e1182, December 2018.

Brunetti MA, Gaynor JW, Retzloff LB, Lehrich JL, Banerjee M, Amula V, Bailly D, Klugman D, Koch J, Lasa J, Pasquali SK, Gaies M: Characteristics, Risk Factors & Outcomes of Extracorporeal Membrane Oxygenation use in Pediatric Cardiac Intensive Care Units. Peds Crit Care Med 19(6): 544-552, June 2018.

Easley RB, Marino BS, Jennings J, Cassedy AE, Kibler KK, Brady KM, Andropoulos DB, Brunetti M, Hogue CW, Heitmiller ES, Lee JK, Spaeth J, Everett AD.: Impaired cerebral autoregulation and elevation in plasma glial fibrillary acidic proteinlevel during cardiopulmonary bypass surgery for CHD. Cardiol Young 28(1): 55-65, Jan 2018.


Johnson JT, Sleeper LA, Chen S, Ohye RG, Gaies MG, Williams IA, Sachdeva, Pruetz JD, Tatum GH, Thacker D, Brunetti MA, Frommelt MA, Jacobs JP, Kirsh JA, Lambert LM, Newburger JW, Pemberton VL, Zyblewski SC, Divanovic AA, Pinto NM for the Pediatric Heart Network Investigators: Associations Between Day of Admission and Day of Surgery on Outcome and Resource Utilization in Infants with Hypoplastic Left Heart Syndrome Undergoing Stage I Palliation From the Single Ventricle Reconstruction Trial. American Journal of Cardiology  116(8): 1263-1269, 2015.

Brunetti MA, Glatz AC, McCardle K, Mott AR, Ravishankar C, Gaynor JW: Risk factors for unplanned readmission of patients to the pediatric cardiac intensive care unit. World Journal for Pediatric and Congenital Heart Surgery 6(4): 597-603, 2015.


Brunetti MA, Jennings JM, Easley RB, Bembea M, Brown A, Heitmiller E, Schwartz JM, Brady KM, Vricella LA, Everett AD: Glial fibrillary acidic protein in children with congenital heart disease undergoing cardiopulmonary bypass. Cardiology in the Young 24(4): 623-631, 2013.2


Brunetti MA, Mahesh M, Nabaweesi R, Locke P, Ziegfeld S, Brown R: Diagnostic radiation exposure in pediatric trauma patients. Journal of Trauma 70(2): E24-E28, 2011.


Brunetti MA, Ringel R, Owada C, Coulson J, Jennings J, Hoyer M, Everett A: Percutaneous closure of patent ductus arteriosus: a multi-institutional registry comparing multiple devices. Catheterization and Cardiovascular Interventions  76(5): 696-702, 2010.




Wild KT, Gray BW, Brunetti M, Connelly JT, Rintoul N. : Extracorporeal Life Support: Neonatal respiratory and cardiac disease.   Extracorporeal Circulation in Theory and Practice. Tschaut RJ. (eds.). Pabst Science Publishers, Lengerich, Germany, Page: 619-627, 2020.

Brunetti MA, Mascio CE, O'Connor MJ. : ECMO as a Bridge to Heart Transplant.   Extracorporeal Membrane Oxygenation: An Interdisciplinary Problem Based Learning Approach. Maybauer MO  (eds.). Oxford University Press, 2020.


Schwartz JM, Brunetti MA. Cyanotic Heart Defects.  Editor Perretta J.  Neonatal and Pediatric Respiratory Care: a Patient Case Method, 1st edition.  Philadelphia, PA: F.A. Davis, 2014.

Peddy SB, Brunetti MA, Schwartz JM. Management of the Pediatric Cardiac Surgical Patient.  Editors Yuh DD, Vricella LA. Johns Hopkins Manual of Cardiothoracic Surgery, 2nd edition.  New York, NY: McGraw Hill, 2014: 973-982. 


Brunetti M, Cohen J. Hematology.  Editors Shilkofksi N, Robertson J. Harriet Lane Handbook, 17th edition.  Philadelphia, PA: Elsevier Mosby, 2005: 335-361.

Posters and Presentations


Brunetti MA, Gaynor JW, Zhang W, Bush LR, Banerjee M, Pasquali SK, Gaies M. : Hospital variation in post-operative cardiac ECMO use and relationship to cardiac surgical mortality.  Oral poster presentation, Pediatric Cardiac Intensive Care Society International Meeting, London November 2019.

Brunetti MA & Murtaugh C. : Implementation of fever guidelines for patients with central lines in a pediatric cardiac ICU. Oral poster presentation, Pediatric Cardiac Intensive Care Society International Meeting, London November 2019.


Brunetti MA, Murtaugh C: Implementation of Fever Guidelines for Patients with Central Lines in a Pediatric Cardiac Intensive Care Unit. CHOP Quality and Safety Day, Children's Hospital of Philadelphia, Philadelphia, PA May 2018 Notes: Poster Presentation.

Invited Lectures


Brunetti MA. "Fever Guidelines in Pediatric CICU Patients with Central Lines", Society of Critical Care Medicine Pediatric Quality and Safety Committee Webinar. May 2019.

Brunetti MA. "ECMO in the Current Era of the Pediatric CICU", CHOP Cardiology Conference, Huntingdon Beach, CA. Feb 2019.

Brunetti MA. "CLABSI Reduction in the CICU", CHOP Cardiology Conference, Huntingdon Beach, CA. Feb 2019.


Brunetti MA. "Hospital Variation in Post-Operative ECMO Use and Relationship to Cardiac Surgical Mortality", PC4 Research in Progress Webinar,  
Pediatric Cardiac Critical Care Consortium Registry. Dec 2018.

Brunetti MA. "Fever Guidelines in Pediatric CICU Patients with Central Lines", Oral presentation, Top Abstract Session, SCCM Quality Summit, Atlanta, GA. Sept 2018.

Brunetti MA. "Characteristics, Risk Factors and Outcomes of Extracorporeal Membrane Oxygenation Use in the Pediatric Cardiac Intensive Care Unit", Oral presentation, Featured Research, World Federation of Pediatric Intensive & Critical Care Societies, Singapore. June 2018.

Awards and Honors

2002, graduated Magna Cum Laude from Jefferson Medical College
2000, 2nd place presentation in student abstract competition, “The Presence of Stroke Risk Factors”, Society of Teachers of Family Medicine Conference
2000, Pathology Program for Advanced Study
2000, Association of Pathology Chairs Pathology Honor Society
2000, Hobart Armory Hare Honor Society
1999-2000, President, Jefferson Pediatric Society
1998-2002, Daughters of the American Revolution Medical Scholarship
1998, graduated Cum Laude from University of Scranton
1998, Biology Honor Society, University of Scranton
1998, Philosophy Honor Society, University of Scranton

Editorial and Academic Positions

Editorial Positions

2015-present, Ad hoc reviewer, World Journal for Pediatric and Congenital Heart Surgery

Academic and Institutional Committees

2016-present, ECMO Operations Committee
2015-present, CLABSI Prevention Committee
2015-present, Associate Director of Simulation, Cardiac Center
2015-present, Chair, CICU CLABSI Prevention Working Group
2015-present, Infection Prevention and Control Committee

Leadership and Memberships

Memberships in Professional Organizations


2017-present, Extracorporeal Life Support Organization (ELSO)
2008-present, Pediatric Cardiac Intensive Care Society


2006-present, Society of Critical Care Medicine
2002-present, American Academy of Pediatrics
 - 2018-present, AAP/SCCM National Quality Committee