Marissa A. Brunetti, MD
Areas of expertise: Extracorporeal life support, Simulation education
Locations: Main Building
About Marissa A. Brunetti, MD
Titles
Attending Intensivist
Co-Director, Extracorporeal Life Support Fellowship
Director of Simulation, Cardiac Center
Associate Professor of Clinical Anesthesiology, Critical Care Medicine, and Pediatrics, University of Pennsylvania Perelman School of Medicine
Certifications
Pediatrics – American Board of Pediatrics
Pediatric Critical Care Medicine – American Board of Pediatrics
Pediatric Cardiology – American Board of Pediatrics
Pediatric Advanced Life Support (PALS)
Advanced Cardiovascular Life Support (ACLS)
Awards and Honors
2002, graduated Magna Cum Laude from Jefferson Medical College
2000, 2nd place presentation in student abstract competition, “The Presence of Stroke Risk Factors”, Society of Teachers of Family Medicine Conference
2000, Pathology Program for Advanced Study
2000, Association of Pathology Chairs Pathology Honor Society
2000, Hobart Armory Hare Honor Society
1999-2000, President, Jefferson Pediatric Society
1998-2002, Daughters of the American Revolution Medical Scholarship
1998, graduated Cum Laude from University of Scranton
1998, Biology Honor Society, University of Scranton
1998, Philosophy Honor Society, University of Scranton
Leadership and Memberships
2023-present, PediECMO Network
2017-present, Extracorporeal Life Support Organization
2008-present, Pediatric Cardiac Intensive Care Society
- 2025-present, Alliance for Women’s Empowerment Special Interest Group, Co-chair
- 2025-present, Diversity, Equity, and Inclusion Committee
2006-present, Society of Critical Care Medicine
2002-present, American Academy of Pediatrics
- 2018-present, Critical Care Medicine Quality Committee
Editorial and Academic Positions
Academic and Institutional Committees
2023-present, CHOP CICU Equity, Diversity, and Inclusion Committee
2023-present, Scholarship Oversight Committee, Pediatric Critical Care Medicine Fellowship Program
2022-present, PediECMO Committee
2021-present, Pediatric Cardiac Critical Care Consortium
- 2021-present, Equity, Diversity, and Inclusion Committee
- 2021-present, Quality Improvement Work Group, Co-chair
2016-present, ECMO Operations Committee
Research Interests
ECMO
Critical cardiac disease
Disparities
Database research
Outcomes research
Education & training
Medical Degree
MD - Jefferson Medical College, Philadelphia, PA
Residency
Pediatrics - Johns Hopkins Hospital, Baltimore, MD
Fellowship
Pediatric Critical Care Medicine - Johns Hopkins Hospital, Baltimore, MD
Pediatric Cardiology - Johns Hopkins Hospital, Baltimore, MD
Publications
Publications
2025
Perry T, Cooper DS, Sweberg T, Jacobs ML, Jacobs JP, Huang B, Chen, C, Thiagarajan RR, Brunetti MA, Lasa JJ, Cheung E, Subramanyan RK, Adachi I, Ashfaq A, Maeda K, Zafar F, Morales DL. Post-cardiotomy extracorporeal membrane oxygenation in children: a report from the Society of Thoracic Surgeons Congenital Heart Surgery Database. Annals of Thoracic Surgery Ann Thorac Surg 2025; 119:413-422.
Perry T, Jacobs ML, Jacobs JP, Sweberg T, Huang B, Chen C, Cooper DS, Thiagarajan RR, Brunetti MA, Lasa JL, Cheung EW, Kumar SR, Adachi I, Ashfaq A, Maeda K, Zafar F, Morales DL. Children Supported with Extracorporeal Membrane Oxygenation Before Cardiac Surgery: Stabilizing the Unstable. A Report from the STS-CHSD. Ann Thorac Surg July 2025 online ahead of print.
2024
Hummel K, Raymond T, Gist KM, Yurasek G, Winder M, Brunetti MA. Current state of quality improvement research across cardiac intensive care units: a Pediatric Cardiac Intensive Care Society (PCICS) survey. Cardiology of the Young 2024; 34:2641-2644.
Brunetti MA, Gaynor JW, Zhang W, Bush LR, Banerjee M, Pasquali SK, Gaies M.
Hospital variation in post-operative cardiac ECMO use and relationship to post-operative mortality. Cardiology of the Young 2024; 34:2543-2550. Top 10 PICU article of 2024 by Pub Med/NLM/NCBI.
2023
Ortmann L, Reeder RW, Raymond TT, Brunetti MA, Himebauch A, Bhakta R, Kempka J, di Bari S, Lasa JJ. Epinephrine dosing strategies during pediatric extracorporeal cardiopulmonary resuscitation reveal novel impacts on survival: A multicenter study utilizing time-stamped epinephrine dosing records. Resuscitation 2023; 188: Online ahead of print.
Brunetti MA, Griffis HM, O’Bryne ML, Glatz AC, Huang J, Schumacher KR, Bailly DK, Domnina Y, Lasa JL, Moga MA, Zaccagni H, Simsic JM, Gaynor JW. Racial and ethnic variation in ECMO utilization and outcomes in pediatric cardiac ICU patients: a multicenter cohort study from the Pediatric Cardiac Critical Care Consortium registry. JACC Advances 2023;2:100634
2020
10. Esangbedo ID, Brunetti MA, Campbell FM, Lasa JJ. Pediatric extracorporeal cardiopulmonary resuscitation: a systematic review. Pediatr Crit Care Med 2020;21:e934-e943.
2019
Noje C, Bembea MM, Nelson McMillan KL, Brunetti MA, Bernier ML, Costabile PM, Klein BL, Duval-Arnould J, Hunt EA, Shaffner DH: A national survey on interhospital transport of children in cardiac arrest. Peds Crit Care Med 20(1): e30-e36, January 2019.
2018
Smith AH, Anand V, Banerjee M, Bates KE, Brunetti MA, Cooper DS, Lehrich J, Mistry KP, Pasquali SK, Shin AY, Tabbutt S, Gaies M: Variation in case-mix adjusted unplanned pediatric cardiac ICU readmission rates. Crit Care Med 46(12): e1175-e1182, December 2018.
Brunetti MA, Gaynor JW, Retzloff LB, Lehrich JL, Banerjee M, Amula V, Bailly D, Klugman D, Koch J, Lasa J, Pasquali SK, Gaies M: Characteristics, Risk Factors & Outcomes of Extracorporeal Membrane Oxygenation use in Pediatric Cardiac Intensive Care Units. Peds Crit Care Med 19(6): 544-552, June 2018.
Easley RB, Marino BS, Jennings J, Cassedy AE, Kibler KK, Brady KM, Andropoulos DB, Brunetti M, Hogue CW, Heitmiller ES, Lee JK, Spaeth J, Everett AD.: Impaired cerebral autoregulation and elevation in plasma glial fibrillary acidic proteinlevel during cardiopulmonary bypass surgery for CHD. Cardiol Young 28(1): 55-65, Jan 2018.
2015
Johnson JT, Sleeper LA, Chen S, Ohye RG, Gaies MG, Williams IA, Sachdeva, Pruetz JD, Tatum GH, Thacker D, Brunetti MA, Frommelt MA, Jacobs JP, Kirsh JA, Lambert LM, Newburger JW, Pemberton VL, Zyblewski SC, Divanovic AA, Pinto NM for the Pediatric Heart Network Investigators: Associations Between Day of Admission and Day of Surgery on Outcome and Resource Utilization in Infants with Hypoplastic Left Heart Syndrome Undergoing Stage I Palliation From the Single Ventricle Reconstruction Trial. American Journal of Cardiology 116(8): 1263-1269, 2015.
Brunetti MA, Glatz AC, McCardle K, Mott AR, Ravishankar C, Gaynor JW: Risk factors for unplanned readmission of patients to the pediatric cardiac intensive care unit. World Journal for Pediatric and Congenital Heart Surgery 6(4): 597-603, 2015.
2013
Brunetti MA, Jennings JM, Easley RB, Bembea M, Brown A, Heitmiller E, Schwartz JM, Brady KM, Vricella LA, Everett AD: Glial fibrillary acidic protein in children with congenital heart disease undergoing cardiopulmonary bypass. Cardiology in the Young 24(4): 623-631, 2013.2
2011
Brunetti MA, Mahesh M, Nabaweesi R, Locke P, Ziegfeld S, Brown R: Diagnostic radiation exposure in pediatric trauma patients. Journal of Trauma 70(2): E24-E28, 2011.
2010
Brunetti MA, Ringel R, Owada C, Coulson J, Jennings J, Hoyer M, Everett A: Percutaneous closure of patent ductus arteriosus: a multi-institutional registry comparing multiple devices. Catheterization and Cardiovascular Interventions 76(5): 696-702, 2010.
Abstracts (includes Posters and Scientific Presentations)
2026
Nitsche LJ, Mak A, Aronowitz D, Keesari R, Baxelbaum K, Mavroudis CD, Anton-Martin P, Brunetti MA, Mahle M, Burnham N, Elias M, Kilbaugh T, Kozyak B, O’Connor M, O’Byrne ML, Ravishankar C, Chen JM, Fuller SM, Gaynor JW. Impact of Repeat Extracorporeal Membrane Oxygenation on Intermediate-term Survival. Poster presentation, Society of Thoracic Surgeons Annual Meeting, February 2026.
2025
Brunetti MA, Shah M, Alexander P, Asija R, Kirsch R, Moga MA, Peddy SB, Rhodes L, Purkey N, Naim M. Gender disparity in pay and promotion in pediatric cardiac critical care. Poster presentation, CHOP Cardiology Conference, February 2025.
Cardoso Cavalcante R, Brunetti M, Vellore S, Hsiung J, Sanderlin R, Anton-Martin P. ECMO discontinuation due to resource limitation: An ELSO Registry Study. Oral presentation, Society of Critical Care Medicine, February 2025.
Payne J, Ortiz P, Foppert L, Fuentes J, Said T, Stegmann T, Flores L, Muralidharan B, Parrish B, Greberman M, Poliziani G, Campisi G, Madrid P, Anton-Martin P, Bilello M, Moran S, Hehir D, Naim MY, Brunetti MA. PROJECT C.L.E.A.R.: Communication and Language Equity through Access to Resources, the CICU Language Optimization Quality Initiative. Poster presentation, CHOP Health Equity Conference, April 2025.
Payne J, Ortiz P, Foppert L, Fuentes J, Said T, Stegmann T, Flores L, Muralidharan B, Parrish B, Greberman M, Poliziani G, Campisi G, Madrid P, Anton-Martin P, Bilello M, Moran S, Hehir D, Brunetti MA, Naim MY. PROJECT C.L.E.A.R.: Communication and Language Equity through Access to Resources, the CICU Language Optimization Quality Initiative. Oral abstract, CHOP Quality and Safety Conference, May 2025. Fourth place abstract presentation.
Cardoso Calvacante R, Brunetti M, Baxelbaum K, Gaynor JW, Thiagarajan R, Jolley MA, Anton-Martin P. A contemporary perspective of postoperative ECMO outcomes in patients after Fontan anastomosis: An ELSO Registry Analysis. Oral presentation, Extracorporeal Life Support Organization Annual Conference, September 2025.
Cardoso Cavalcante R, Brunetti M, Vellore S, Hsiung J, Sanderlin R, Anton-Martin P. ECMO discontinuation due to resource limitation in neonatal and pediatric cardiac patients: An ELSO Registry Study. Oral presentation, Extracorporeal Life Support Organization Annual Conference, September 2025.
Mahmood H, Himebauch AS, Anton-Martin P, Baxelbaum K, Gaynor JW, Rintoul N, Brunetti MA. Neuromonitoring practices in pediatric extracorporeal membrane oxygenation patients: a survey of North American centers. Oral presentation, Extracorporeal Life Support Organization Annual Conference, September 2025.
Payne J, Ortiz P, Foppert L, Fuentes J, Said T, Stegmann T, Flores L, Muralidharan B, Parrish B, Greberman M, Poliziani G, Campisi G, Madrid P, Anton-Martin P, Bilello M, Moran S, Hehir D, Brunetti MA, Naim MY. PROJECT C.L.E.A.R.: Communication and Language Equity through Access to Resources, the CICU Language Optimization Quality Initiative. Poster presentation, Pediatric Cardiac Intensive Care Society, October 2025.
Cardoso Calvacante R, Brunetti M, Baxelbaum K, Gaynor JW, Thiagarajan R, Jolley MA, Anton-Martin P. A contemporary perspective of postoperative ECMO outcomes in patients after superior cavopulmonary anastomosis: An ELSO Registry Analysis. Poster presentation, Pediatric Cardiac Intensive Care Society Annual Meeting, October 2025.
2024
Perry T, Cooper DS, Zafar F, Huang B, Chen C, Thiagarajan R, Brunetti MA, Lasa JJ, Sweberg T, Jacobs ML, Jacobs JP, Cheung E, Subramanyan RK, Adachi I, Ashfaq A, Maeda K, Morales DL. Outcomes in children with congenital heart disease who undergo post-cardiotomy extracorporeal membrane oxygenation: a report from the Society of Thoracic Surgeons National Database. Oral abstract, Society of Thoracic Surgeons Annual Meeting, January 2024.
Stormes B, Brunetti MA, Parrish BT, Lindell RB, Himebauch A, Fitzgerald J. Outcomes of Pediatric Cardiac ICU Patients with Intracranial Hemorrhage on ECMO. Oral abstract, Society of Critical Care Medicine Congress, January 2024
Cardoso Cavalcante R, Brunetti M, Vellore S, Hsiung J, Sanderlin R, Anton-Martin P. ECMO discontinuation due to resource limitation in neonatal and pediatric cardiac patients: An ELSO Registry Study. Poster presentation, Pediatric Cardiac Intensive Care Society Congress, November 2024
2023
Finnegan LM, Ade A, Rintoul N, Brunetti MA, Srinivasan L. Applying the Sepsis Risk Score to Asymptomatic Neonates with Complex Congenital Anomalies. Pediatric Academic Societies, April 2023
Plummer S, Brunetti M, DiMaria K, Diaz I, Fernandes B, Figueroa M, Hills B, Jacobs J, Kipps A, Kulkarni A, Nawathe P, Patel S, Tjeong YL, Welke K, Chan T. The Joint Equity, Diversity, and Inclusion Committee: a unique collaboration between collaboratives to mitigate disparities in pediatric cardiology. Poster presentation, World Congress of Pediatric Cardiology and Cardiac Surgery, August 2023
Hummel K, Gist K, Raymond TT, Brunetti MA. Quality improvement research across pediatric cardiac centers: a survey from the PCICS QI-S Committee. Poster presentation, World Congress of Pediatric Cardiology and Cardiac Surgery, August 2023.
Lectures by Invitation
2025
Brunetti M. CHOP ECMO course, July 2025
2024
Brunetti M. CHOP ECMO course, July 2024
Brunetti M. CHOP PICU Fellow Simulation Boot Camp, July 2024
Brunetti M. Gender Disparity in Pay and Promotion in Pediatric Cardiac Critical Care, Pediatric Cardiac Intensive Care Society Annual Meeting, November 2024
2023
Brunetti M. CHOP ECMO course, July 2023
Brunetti M. CHOP PICU Fellow Simulation Boot Camp, July 2023
Editorials, Reviews, Chapters
2022
Brunetti MA, Mascio CE, O’Connor MJ. ECMO as Bridge to Pediatric Heart Transplantation. Editor Maybauer MO. Extracorporeal Membrane Oxygenation: An Interdisciplinary Problem Based Learning Approach. Oxford University Press 2022
2021
Peer reviewer, National NICU Neonatology Curriculum. Editors Glass K and Zenge J. 2021
Payton KSE, Brunetti MA. Antibiotic Stewardship in Pediatrics. Advances in Pediatrics 2021
2020
Wild KT, Gray BW, Brunetti M, Connelly JT, Rintoul N. : Extracorporeal Life Support: Neonatal respiratory and cardiac disease. Extracorporeal Circulation in Theory and Practice. Tschaut RJ. (eds.). Pabst Science Publishers, Lengerich, Germany, Page: 619-627, 2020.
Brunetti MA, Mascio CE, O'Connor MJ. : ECMO as a Bridge to Heart Transplant. Extracorporeal Membrane Oxygenation: An Interdisciplinary Problem Based Learning Approach. Maybauer MO (eds.). Oxford University Press, 2020.
2014
Schwartz JM, Brunetti MA. Cyanotic Heart Defects. Editor Perretta J. Neonatal and Pediatric Respiratory Care: a Patient Case Method, 1st edition. Philadelphia, PA: F.A. Davis, 2014.
Peddy SB, Brunetti MA, Schwartz JM. Management of the Pediatric Cardiac Surgical Patient. Editors Yuh DD, Vricella LA. Johns Hopkins Manual of Cardiothoracic Surgery, 2nd edition. New York, NY: McGraw Hill, 2014: 973-982.
2005
Brunetti M, Cohen J. Hematology. Editors Shilkofksi N, Robertson J. Harriet Lane Handbook, 17th edition. Philadelphia, PA: Elsevier Mosby, 2005: 335-361.