Caroline Diorio, MD, FRCPC, FAAP

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Caroline Diorio, MD, FRCPC, FAAP, is an attending physician with the Cancer Center at Children's Hospital of Philadelphia.

Locations: Main Hospital
Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

Education and Training

Medical School

MD - University of Toronto, Toronto, Ontario


Pediatrics - McMaster University, Hamilton, Ontario


Hematology/Oncology - Children’s Hospital of Philadelphia, Philadelphia, PA
Clinical Practice Guideline - Pediatric Oncology Group of Ontario and Sick Kids Hospital, Toronto, Ontario

Graduate Degree

MS in Translational Research - University of Pennsylvania, Philadelphia, PA

Titles and Academic Titles

Attending physician

Assistant professor, Perelman School of Medicine at the University of Pennsylvania 

Departments and Services




Diorio C, Afanasiev M, Salena K, Marjerrison S. ‘A world of competing sorrows’: a mixed methods analysis of media reports of children with cancer abandoning conventional treatment. PLoS One. 2018 Dec 21;13(12):e0209738. doi: 10.1371/journal.pone.0209738. eCollection 2018.

Diorio C & Nowaczyk M. Half as Sad: A Plea for Narrative Medicine in Residency Training. Pediatrics. 2019 Jan;143(1). pii: e20183109. doi: 10.1542/peds.2018-3109. Epub 2018 Dec 6.

Diorio C, Robinson PD, Ammann RA, Castagnola E, Erikson K, Esbenshade A, Fisher BT, Haeusler G, Kuczynski S, Lehrnbecher T, Phillips R, Cabral S, Dupuis L, Sung L. Guideline for the Management of Clostridium Difficile Infection in Children and Adolescents with Cancer and Pediatric Hematopoietic Stem Cell Transplantation Recipients. J Clin Oncol. 2018 Sep 14: JCO1800407.

Diorio, C, Lin, M, Ginn E & Ladas, EJ. Psychosocial Determinants of Physical Activity and Dietary Behaviors in Adolescents and Young Adults with Cancer and Survivors. Pediatr Blood Cancer. 2018 May 24:e27243.

Radossi AL, Taromina K, Marjerrison S, Diorio C, Similio R, Njuguna F, Afungcwhi GM, Ladas EJ. A systematic review of integrative clinical trials for supportive care in pediatric oncology: a report from the International Society of Pediatric Oncology, T&CM collaborative. Support Care Cancer. 2018 Feb;26(2):375-391.


Diorio, C, Salena, K, Ladas, EJ, Lam, CG, Afungcwhi, GM, Njuguna, F, & Marjerrison, S. Traditional and complementary medicine used with curative intent in childhood cancer: A systematic review. Pediatric Blood & Cancer. 2017 Sep;64(9).


Diorio C, Lam C., Ladas E., Njuguna F., Mbah G., Taromina K.M., & Marjerrison S. Global prevalence of traditional and complementary medicine in pediatric cancer: systematic review. Journal of Global Oncology (2016): JGO-2016.

Diorio C, Celis Ekstrand A, Hesser T, O’Sullivan C, Lee M, Schechter T, Sung L. Development of an individualized yoga intervention to address fatigue in hospitalized children undergoing intensive chemotherapy. Integr Cancer Ther 2016; 15(3): 279-84. 


Diorio C, Schechter T, Lee M, O’Sullivan C, Hesser T, Tomlinson D, Piscione J, Armstrong C, Tomlinson G, Sung L. A pilot study to evaluate the feasibility of individualized yoga for inpatient children receiving intensive chemotherapy. BMC Complement Altern Med 2015; 15:2.


Tomlinson D*, Diorio C*, Beyenne J, Sung L. The effect of exercise on cancer-related fatigue: a meta-analysis. Am J Phys Med Rehabil. 2014 Aug;93(8):675-86.


Diorio C, Tomlinson D, Boydell KM, Regier DA, Ethier MC, Alli A, Alexander S, Gassas A, Taylor J, Kellow C, Mills D, Sung L. Attitudes toward infection prophylaxis in pediatric oncology: a qualitative approach. PLoS One 2012; 7(10):e47815.

Regier DA, Diorio C, Ethier MC, Alli A, Alexander S, Boydell KM, Gassas A, Taylor J, Kellow C, Mills D, Sung L. Discrete choice experiment to evaluate factors that influence preferences for antibiotic prophylaxis in pediatric oncology. PLoS One 2012; 7(10):e47470.  

Gavidia R, Fuentes SL, Vasquez R, Bonilla M, Ethier MC, Diorio C, Caniza M, Howard SC, Sung L. Low socioeconomic status is associated with prolonged times to assessment and treatment, sepsis and infectious death in pediatric fever in el Salvador. PLoS One 2012; 7(8):e43639.

Teuffel O, Cheng S, Ethier MC, Diorio C, Martino J, Mayo C, Wing R, Sung L, Alibhai SM. Health-related quality of life anticipated with different management strategies for febrile neutropenia in adult cancer patients. Support Care Cancer 2012; 20(11):2755-64.


Diorio C, Martino J, Boydell K, Ethier MC, Mayo C, Wing R, Teuffel O, Sung L, Tomlinson D. Parental perspectives on inpatient versus outpatient management of pediatric febrile neutropenia. J Pediatr Oncol Nurs 2011; 28(6):355-62.

Cheng S, Teuffel O, Ethier MC, Diorio C, Martino J, Mayo C, Regier D, Wing R, Alibhai SM, Sung L. Health-related quality of life anticipated with different management strategies for pediatric febrile neutropenia. Br J Cancer 2011; 105(5):606-611.

Bender JL, Radhakrishnan A, Diorio C, Englesakis M, Jadad AR. Can pain be managed through the Internet? A systematic review of randomized controlled trials. Pain 2011; 152(8):1740-1750.


Wang B, Mao YK, Diorio C, Pasyk M, Wu RY, Bienenstock J, Kunze WA. Luminal administration ex vivo of a live Lactobacillus species moderates mouse jejunal motility within minutes. FASEB J 2010; 24(10):4078-4088.

Wang B, Mao YK, Diorio C, Wang L, Huizinga JD, Bienenstock J, Kunze WA. Lactobacillus reuteri ingestion and IK(Ca) channel blockade have similar effects on rat colon motility and myenteric neurones. Neurogastroenterol Motil 2010; 22(1):98-107.

Posters and Presentations


Diorio C, Dupuis L. Chemotherapy-induced Nausea and Vomiting: Understanding Patient and Parent Preference for Home Interventions during ALL Maintenance Therapy. Presented at the Children's Oncology Group (COG) Fall Meeting, Atlanta, Georgia, September 2019.

Awards and Honors

2019, ITMAT Scholarship, University of Pennsylvania
2014, Dr. Carl Witus (3T6) Memorial Prize in Pediatrics , University of Toronto
2013, Class of Medicine 1924 War Service Scholarship, University of Toronto
2012-2013, Dr. Frederick James Colling OBE Memorial Scholarship, University of Toronto
2012, Thomas R. Turrall Memorial Scholarship, University of Toronto
2011-2012, CREMS Scholar, University of Toronto
2008-2010, Millennium Excellence Award Laureate, Wilfrid Laurier University
2006-2010, Dean’s Honour Roll, Wilfrid Laurier University
2009, F. W. Minkler Scholarship, Wilfrid Laurier University
2006, Lieutenant-Governor’s Community Volunteer Award

Editorial and Academic Positions

Editorial Positions

2018-2019, Reviewer, Integrative Cancer Therapy

Leadership and Memberships

Memberships in Professional Organizations


2018-present, Royal College of Physicians of Canada, Fellow
2017-present, International Society of Pediatric Oncology
2010-present, Canadian Medical Association


2018-present, American Board of Pediatrics, Fellow