![Jonathan J. Edwards, MD](/sites/default/files/styles/crop_and_center_300x375/public/providers-new-edwards-jonathan.jpg?itok=YBog1vCS)
Jonathan J. Edwards, MD
Areas of expertise: Molecular mechanisms of right ventricular failure and remodeling, Familial cardiomyopathy
About Jonathan J. Edwards, MD
Jonathan Edwards, MD is an attending physician in the Division of Cardiology, Section of Pediatric Heart Failure and Transplantation. He has special clinical and research interests in the genetic and molecular causes of right ventricular heart failure and cardiomyopathy. Dr. Edwards sees infants and children of all ages in the Cardiomyopathy Genetics clinic, including screening for familial forms of cardiomyopathy.
Dr. Edwards research focuses primarily on the deciphering the molecular mechanisms of right ventricular failure, which is critical given the prevalence of right ventricular failure in children and adolescents with congenital heart defects and the lack of proven medical therapies. This work integrates translational and basic science models, and has been supported through numerous funding sources, including from the National Heart, Lung, and Blood Institute and foundational and industry sponsored grants. Dr. Edwards has also investigated genetic causes of congenital heart disease, immunologic desensitization for patients listed for transplant, and outcomes of patients supported with ventricular assist devices.
Titles
Attending Physician
Awards and Honors
2016, Kurt Hirschhorn Clinician-Scientist Award, Icahn School of Medicine at Mount Sinai
2016, House Office Research Award, Society for Pediatric Research
2011, Sarnoff Cardiovascular Research Foundation, Research Fellow
2009 Student Research Program, American Pediatrics Society/Society for Pediatrics Research
2008, Summa Cum Laude, East Carolina University
2008, Robert H Wright Alumni Leadership Award, East Carolina University
2007, Gerhard W Kalmus Scholarship, East Carolina University
2007, ACS Undergraduate Analytical Chemistry Award, East Carolina University
2007, Dr. Keith and Susan Holmes Scholastic Award, East Carolina University
Leadership and Memberships
2018–present, International Society for Heart and Lung Transplantation
2016–present, American College of Cardiology
2011–present, American Heart Association
Editorial and Academic Positions
2020-present, Clinical Genetics, Reviewer
2019-present, Archives of Disease in Childhood, Reviewer
Education & training
Medical Degree
MD - Wake Forest School of Medicine of Wake Forest Baptist Medical Center, Winston-Salem, NC
Residency
Pediatrics (Physician Scientist Research Residency) - Icahn School of Medicine at Mount Sinai, New York, NY
Fellowship
Pediatric Cardiology - Children's Hospital of Philadelphia, Philadelphia, PA
Pediatric Heart Failure and Transplantation - Children's Hospital of Philadelphia, Philadelphia, PA
Publications
Books
Book chapters
Edwards J, Lin K, Rossano J. Diagnosis, Evaluation, and Management of Pediatric Heart Failure. Pediatric Cardiology: Fetal, Pediatric and Adult Congenital Cardiology (First Edition). Pahl E. and Abdulla R. (eds.) Elsevier [In Press]
Grants
Active
1K08HL159311-01 NIH/NHLBI Edwards, Jonathan (PI)
Defining the Role of ROR2 in Right Ventricular Failure Pathogenesis
Role: Principal Investigator
Completed
5T32 HL007915 NIH/NHLBI Levy, R and Rossano, J (PI)
Training in Molecular Therapeutics for Pediatric Cardiology
Role: Research Trainee
CHD Coalition (PI) Edwards, J
Investigating differential gene expression associated with right ventricular remodeling
Role: Principal Investigator
ENTELLIGENCE Young Investigator Award Program (PI) Edwards, J
Investigating altered right ventricular myocardial gene expression and biomarkers patterns associated with adaptive and pathologic remodeling in diverse human models
Role: Principal Investigator
Matthew’s Heart of Hope (PI) Edwards, J
WNT the Right Ventricle’s Had Enough
Role: Principal Investigator