Michael J. Fisher, MD

Michael J. Fisher, MD

Michael J. Fisher, MD, is Chief of the Section of Neuro-Oncology, Director of the Neuro-Oncology Fellowship Program and Director of the Neurofibromatosis Program at Children's Hospital of Philadelphia. He has a special interest in brain tumors and neurofibromatosis.

Areas of Expertise: Neurofibromatosis (NF) and NF-related tumors, Optic pathway gliomas, Low-grade gliomas, Plexiform neurofibromas, Pediatric brain tumors, Atypical teratoid rhabdoid tumor, Medulloblastoma
Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

Education and Training

Medical School

MD - Harvard Medical School, Cambridge, MA

Internship

Pediatrics - Children's Hospital Boston, MA

Residency

Pediatrics - Children's Hospital Boston, MA

Fellowship

Hematology/Oncology - The Children's Hospital of Philadelphia, Philadelphia, PA
Neuro-Oncology - The Children's Hospital of Philadelphia, Philadelphia, PA

Board Certification

American Board of Pediatrics
American Board of Pediatrics/Pediatric Hematology-Oncology

Undergraduate Degree

BA in Psychology - Amherst College, Amherst, MA

Titles and Academic Titles

Attending Physician

Chief, Section of Neuro-Oncology

Director, Neuro-Oncology Fellowship Program

Director, Neurofibromatosis Program

Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania

Conditions Treated

Departments and Services

Publications

Papers

2015

Green D, Merchant TE, Billups CA, Stokes DC, Broniscer A, Bartels U, Chintagumpala M, Hassall TE, Gururangan S, McCowage GB, Heath JA, Cohn RJ, Fisher MJ,  A, Robinson GW, Gajjar A. Pulmonary Function after Treatment for Embryonal Brain Tumors on SJMB03 that Included Craniospinal Irradiation. Int J Radiat Oncol Biol Phys. 2015 Sep 1;93(1):47-53.

de Blank PMK, Fisher MJ, Lu L, Leisenring WM, Ness KK, Sklar CA, Stovall M, Vukadinovich C, Robison LL, Armstrong GT, Krull KR. The Impact of Vision Loss Among Survivors of Childhood Central Nervous System Astroglial Tumors.  Cancer. 2016 Mar 1;122(5):730-9.

Hobbie W, Ogle S, Reilly M, Barakat L, Lucas M, Ginsberg JP, Fisher MJ,  Volpe EM, Hardie T, Deatrick JA. Adolescent and Young Adult Survivors of Childhood Brain Tumors: Life after Treatment in their Own Words. Cancer Nurs. 2016 Mar-Apr;39(2):134-43.

Xu H, Robinson GW, Huang J, Yew-Suang Lim J, Zhang H, Bass JK, Broniscer A, Chintagumpala M, Bartels U, Gururangan S, Hassall T, Fisher M, Cohn R, Yamashita T, Teitz T, Zuo J, Onar-Thomas A, Gajjar A, Stewart CF, Yang JJ.  Common Variants in ACYP2 Influence Susceptibility to Cisplatin-induced Hearing Loss. Nat Genet. 2015 Mar;47(3):263-6.

Emoto C, Fukuda T, Mizuno T, Cox S, Schniedewind B, Christians U, Widemann BC, Fisher MJ, Weiss B, Perentesis J, Vinks AA. Age-dependent Changes in Sirolimus Metabolite Formation in Patients with Neurofibromatosis Type 1. Ther Drug Monit. 2015 Jun;37(3):395-9.

Weiss B, Widemann BC, Wolters P, Dombi E, Vinks  A, Cantor A, Perentesis J, Schorry E, Ullrich N, Gutmann DH, Tonsgard J, Viskochil D, Korf B, Packer RJ, Fisher MJ. Sirolimus for Progressive Neurofibromatosis Type 1-Associated Plexiform Neurofibromas: A Neurofibromatosis Clinical Trials Consortium Phase II Study. Neuro-Oncology, 17(4):596-603, 2015.

Packer RJ, Rood BR, Fisher MJ, Kilburn L, Hwang E, LaFond D, Smith C, Pouissant T, Goldman S, Lullo R, Banerjee A, Kun L, Boyett J, Onar-Thomas A, Wu S, Fouladi M. Phase I and Pharmacokinetic Trial of PTC299 in Pediatric Patients with Refractory or Recurrent Central Nervous System Tumors: a PBTC Study. J Neurooncol. 2015 Jan;121(1):217-24.

Warrington NM, Sun T, Luo J, McKinstry RC, Parkin PC, Ganzhorn S, Spoljaric D, Albers AC, Merkelson A, Stewart DR, Stevenson DA, Viskochil D, Druley TE, Forys JT, Reilly KM, Fisher MJ, Tabori U, Allen JC, Schiffman JD, Gutmann DH, Rubin JB.  The Cyclic AMP Pathway is a Sex-Specific Modifier of Glioma Risk in Type 1 Neurofibromatosis Patents.  Cancer Research, 75(1):16-21, 2015.

Plotkin SR, Albers A, Babovic-Vuksanovic D, Blakeley JO, Breakefield X, Dunn C , Fisher MJ, Giovannini M, Gutmann D, Kalamarides M, McClatchey A, Messiaen L, Morrison H, Parkinson D, Stemmer-Rachamimov AO, Van Raamsdonk C, Riccardi VM, Rosser T, Schindeler A, Smith MJ, Stevenson DA, Ullrich N, van der Vaart T, Weiss B, Widemann B, Zhu Y, Bakker A, Lloyd AC.  Update from the 2013 International Neurofibromatosis Conference. American Journal of Medical Genetics, 164A(12):2969-78, 2014.

2014

Karajannis MA, Legault G, Fisher MJ, Milla SS, Cohen KJ, Wisoff JH, Harter DH, Goldberg JD, Hochman T, Merkelson A, Bloom MC, Sievert AJ, Resnick AC, Dhall G, Jones DTW, Korshunov A, Pfister SM, Eberhart CG, Zagzag D, Allen JC.  Phase II Study of Sorafenib in Children with Recurrent or Progressive Low-Grade Astrocytomas.  Neuro-Oncology, 16(10):1408-16, 2014.

Betensky M, Witmer C, Fisher MJ, Nance S, Weiss MJ, Sesok-Pizzini DA.  Immune Hemolytic Anemia with Drug-Induced Antibodies to Carboplatin and Vincristine in a Pediatric Patient with an Optic Pathway Glioma.  Transfusion, 54(11):2901-5, 2014.

Deatrick JA, Hobbie W, Ogle S, Fisher MJ, Barakat L, Hardie T, Reilly M, Li Y, Ginsberg JP.  Competence in Caregivers of Adolescent and Young Adult Childhood Brain Tumor Survivors.  Health Psychology, 33(10):1103-12, 2014.

Fisher MJ, Loguidice M, Gutmann DH, Listernick R, Ferner RE, Ullrich NJ, Packer RJ, Tabori U, Hoffman RO, Ardern-Holmes SL, Hummel TR, Hargrave DR, Bouffet E, Charrow J, Bilaniuk LT, Balcer LJ, D'Agostino McGowan L, Liu GT.  Gender as a Disease Modifier in Neurofibromatosis Type 1 Optic Pathway Glioma.  Annals of Neurology, 75(5):799-800, 2014.

Delgado J, Jaramillo D, Ho-Fung V, Fisher MJ, Anupindi SA.  MRI features of plexiform neurofibromas involving the liver and pancreas in children with Neurofibromatosis Type 1.  Clinical Radiology, 69(6):e280-284, 2014.

de Blank P, Cole K, Kersun L, Green A, Wilkes JJ, Belasco J, Bagatell R, Bailey LC, Fisher MJ.  FDG-PET in two cases of neurofibromatosis type 1 and atypical malignancies. Current Oncology, 21(2):e345-348, 2014.

Gurney JG, Bass JK, Onar-Thomas A, Huang J, Chintagumpala M, Bouffet E, Hassall T, Gururangan S, Heath J, Kellie S, Cohn R, Fisher MJ, Pai-Panandikar A, Merchant TE, Srinivasan A, Wetmore C, Qaddoumi I, Stewart CF, Armstrong GT, Broniscer A, Gajjar A. Evaluation of amifostine for protection against cisplatin-induced serious hearing loss in children treated for average risk or high risk medulloblastoma. Neuro-Oncology, 16(6):848-855, 2014.

Weiss B, Widemann BC, Wolters P, Dombi E, Vinks  AA, Cantor A, Korf  B, Perentesis J, Gutmann DH, Schorry E, Packer R, Fisher MJ.  Sirolimus for non-Progressive NF1-Associated Plexiform Neurofibromas: An NF Clinical Trials Consortium Phase II Study.  Pediatric Blood & Cancer, 61:982–986, 2014.

Bass JK, Huang J, Onar-Thomas A, Chang KW, Bhagat SP, Chintagumpala M, Bartels U, Gururangan S, Hassall T, Heath JA, McCowage G, Cohn RJ, Fisher MJ, Robinson G, Broniscer A, Gajjar A, Gurney JG.  Concordance between the Chang and the International Society of Pediatric Oncology (SIOP) ototoxicity grading scales in patients treated with cisplatin for medulloblastoma.  Pediatric Blood & Cancer, 61:601–605, 2014.

Widemann B, Acosta M, Ammoun S, Belzberg A, Bernards A, Blakeley J, Bretscher A, Cichowski K, Clapp W, Dombi E, Evans GD, Ferner R, Fernandez-Valle C, Fisher MJ, Giovanini M, Gutmann D, Hanemann O, Hennigan R, Huson S, Ingram D, Kissil J, Korf B, Legius E, Packer RJ, McClatchey A, McCormick F, North K, Pehrsson M, Plotkin S, Ramesh V, Ratner N, Schirmer S, Sherman L, Shorry E, Stevenson D, Stewart D, Ullrich N, Annette C. Bakker AC, Helen Morrison H. CTF meeting 2012: Translation of the basic understanding of the biology and genetics of NF1, NF2, and Schwannomatosis towards the development of effective therapies.  Am J Med Genet A, 164A(3):563-578, 2014.

2013

Widemann BC, Blakeley JO, Dombi E, Fisher MJ, Hanemann CO, Walsh KS, Wolters PL, Plotkin SR.  Future Directions for the REiNS International Consortium.  Neurology, 81(Suppl 1):S41–S44, 2013.

Dombi E, Ardern-Holmes SL, Babovic-Vuksanovic D, Barker FG, Connor S, Evans DG, Fisher MJ, Goutagny S, Harris GJ, Jaramillo D, Karajannis MA, Korf BR, Mautner V, Plotkin SR, Poussaint TY, Robertson K, Shih C-S, Widemann BC, for the REiNS International Collaboration.  Recommendations for Imaging Tumor Response in Neurofibromatosis Clinical Trials.  Neurology, 81(Suppl 1):S33–S40, 2013.

Fisher MJ, Avery RA, Allen JC, Ardern-Holmes SL, Bilaniuk LT, Ferner RE, Gutmann DH, Listernick R, Martin S, Ullrich NJ, Liu GT, for the REiNS International Collaboration.  Functional outcome measures for NF1-Associated Optic Pathway Glioma Clinical Trials.  Neurology, 81(Suppl 1):S15–S24, 2013.

Plotkin SR, Blakeley JO, Dombi E, Fisher MJ, Hanemann CO, Walsh KS, Wolters PL, Widemann BC.  Achieving Consensus for Clinical Trials: the Response Evaluation in Neurofibromatosis and Schwannomatosis (REiNS) International Collaboration.  Neurology, 81(Suppl 1):S1–S5, 2013.

Scott JR, Courter JD, Saldaña SN, Widemann BC, Fisher M, Weiss B, Perentesis J, Vinks AA.  Population Pharmacokinetics of Sirolimus in Pediatric Patients With Neurofibromatosis Type 1.  Ther Drug Monit, 35(3):332-337, 2013.

de Blank PMK, Berman JI, Liu GT, Roberts TPL, Fisher MJ.  Fractional Anisotropy of the Optic Radiations is Associated with Visual Acuity Loss in Optic Pathway Gliomas of Neurofibromatosis Type 1.  Neuro-Oncology, 15(8):1088-1095, 2013.

Liu GT, Katowitz JA, Rorke-Adams LB, Fisher MJ.  Optic Pathway Gliomas: Neoplasms, not Hamartomas.  JAMA Ophthalmology, 131(5):646-650, 2013.

Kranick SM, Campen CJ, Kasner SE, Kessler SK, Zimmerman RA, Lustig RA, Phillips PC, Beslow LA, Ichord R, Fisher MJ.  Headache as a Risk Factor for Neurovascular Events in Pediatric Brain Tumor Patients. Neurology, 80(16):1452-1456, 2013.

Hwang EI, Jakacki RI, Fisher MJ, Kilburn LB, Horn M, Vezina G, Rood BR, Packer RJ.  Long-term efficacy and toxicity of bevacizumab-based therapy in children with recurrent low-grade gliomas.  Pediatric Blood & Cancer, 60(5):776-782, 2013.

Abstracts

2013

Paltin I, Minturn J, Fisher M, Barakat L.  Prospective case study of two 2 year olds with posterior fossa ependymoma treated with proton radiation therapy. Annual meeting of the American Academy of Clinical Neuropsychology, Chicago, IL, June 2013.

Green DM, Merchant TE, Billups CA,  Stokes DC, Broniscer A, Srinivasan A, Chintagumpala M, Hassall TE, Bouffet E, Gururangan S, Kellie SJ, Ashley DM, Cohn RJ, Fisher MJ, Gajjar AJ. Pulmonary function after treatment for embryonal brain tumors on SJMB03 that included craniospinal irradiation.  49th Annual Meeting of the American Society of Clinical Oncology, Chicago, IL.  Journal of Clinical Oncology, 31(15Suppl): May 2013.

Chi S, Cohen K, Fisher M, Biegel J, Bowers D, Fangusaro J, Manley P, Janss A, Zimmerman MA; Kieran M.  Long Term Outcomes from a Phase II Study of Multi-Agent Intrathecal and Systemic Chemotherapy with Age- and Risk-Adapted Radiation Therapy for Children with Newly Diagnosed CNS Atypical Teratoid/Rhabdoid Tumor (DFCI #02-294).  2nd Annual Pediatric Neuro-Oncology Basic and Translational Research Conference, Fort Lauderdale, FL May 2013 (Neuro-Oncology 15(suppl 1):i36, 2013).

Books

Chapters

2013

Fisher MJ, Balamuth NJ, Rheingold SR.  Oncologic Diseases.  In: Litman RS, ed. Basics of Pediatric Anesthesia.  Philadelphia: Elsevier Mosby, 2013, p.47-54.

de Blank PMK, Liu GT, Fisher MJ.  Outcome Measures for Optic Pathway Gliomas.  In: Karajannis MA, Allen JC, eds.  Neurofibromatosis Type 1: Symptoms, Treatment and Prognosis.  Hauppauge: Nova Science Publishers, Inc., 2013, p.75-100.

2012

McLaughlin EJ, Fisher MJ, Sutton LN, Storm PB.  Brain Tumors.  In: Grosfeld, O’Neil, Fonkalsrud, Coran, eds.  Pediatric Surgery, 7th ed. Philadelphia: Elsevier Saunders, 2012, p.591-604.

Fisher MJ.  Brain tumors.  In: Schwartz MW, ed.  The 5-Minute Pediatric Consult, 6th ed. Philadelphia: Lippincott William & Wilkins, 2012, p.120-121.

2011

Fisher MJ, Rheingold SR. Oncologic Emergencies.  In: Pizzo PA, Poplack DG, eds. Principles and Practice of Pediatric Oncology, 6th ed. Philadelphia: Lippincott Williams & Wilkins, 2011, p.1125-1151.

2008

Fisher MJ, Minturn J, Armstrong G, Phillips PC. Brain tumors. In: Brodeur GM, Manno CS, editors. Requisites in pediatrics: hematology and oncology. Philadelphia: Elsevier Mosby; 2008.

Fisher MJ. Brain tumors. In: Schwartz MW, editor. The 5-minute pediatric consult. 5th ed. Philadelphia: Lippincott William & Wilkins; 2008. p. 120-21.

2006

Fisher MJ, Phillips PC. PET imaging of brain tumors. In: Charron M, editor. Practical pediatric PET imaging. New York: Springer Science + Business Media, Inc.; 2006. p. 175-219.

2005

Fisher MJ. Brain tumors. In: Schwartz MW, editor. The 5-minute pediatric consult. 4th ed. Philadelphia: Lippincott William & Wilkins; 2005. p. 194-95.

2004

Fisher MJ, Marino BS, Litman RS. Oncological diseases. In: Litman RS, editor. Pediatric anesthesia: the requisites in anesthesiology. Philadelphia: Elsevier Mosby; 2004. p. 60-7.

2003

Fisher MJ, Kramer DL, Needle M. Brain tumors. In: Schwartz MW, editor. The 5-minute pediatric consult. 3rd ed. Baltimore: Willian and Wilkins; 2003. p. 190-91.

2001

Fisher MJ, Cohen A. Normal red blood cell indices and differential diagnosis of anemia. In: Polin RA, Spitzer A, editors. Fetal and neonatal secrets. Philadelphia: Hanley and Belfus, Inc.; 2001. p. 227-29.

Posters and Presentations

2014

Levin MH, Armstrong GT, Broad JH, Zimmerman R, Bilaniuk LT, Feygin T, Liu GT, Fisher MJ.  Risk of Optic Pathway Glioma Development in Neurofibromatosis Type 1 (NF1) Patients with Optic Nerve Tortuosity or Thickness.  Poster presentation at the 2014 Annual Meeting of the American Academy of Ophthalmology. Chicago, IL, October 2014.

Paltin I, Hill-Kayser CE, Lustig RA, Minturn, JE, Belasco JB, Cole KA, Phillips PC, Waanders AJ, Fisher MJ.  Relative differences in risk for neuropsychological outcomes post proton radiation for infratentorial versus supratentorial pediatric brain tumors. Poster presentation at the 46th Congress of the International Society of Paediatric Oncology, Toronto, Canada, October 2014.

Hollander A, Lustig RA, Tochner Z, Paltin I, Both S, Zhai H, Fisher MJ, Minturn JE, Phillips P, Hill-Kayser CE.  Acute Toxicities and Treatment Outcomes for Pediatric Medulloblastoma Patients Treated with Proton-Based Craniospinal Irradiation.  Poster presentation at the 46th Congress of the International Society of Paediatric Oncology, Toronto, Canada, October 2014.

Hill-Kayser CE, Tochner Z, Fisher MJ, Minturn J, Belasco J, Bagatell R, Balamuth N, Womer R, Reilly A, Phillips P, Lustig RA.  Proton Radiation for Treatment of Children Less Than 18 months of Age.  Poster presentation at the 46th Congress of the International Society of Paediatric Oncology, Toronto, Canada, October 2014.

Green DM, Merchant TE, Billups C, Stokes DC, Broniscer A, Bartels U, Chintagumpala M, Hassall TE, Gururangan S, McCowage GB, Heath JA, Cohn RJ, Fisher MJ, Srinivasan A, Robinson GW, Gajjar A.  Pulmonary Function after Treatment for Embryonal Brain Tumors on SJMB03 that Included Craniospinal Irradiation.  Poster presentation at the 46th Congress of the International Society of Paediatric Oncology, Toronto, Canada, October 2014.

Hollander A, Both S, Zhai H, Lustig RA, Tochner Z, Fisher MJ, Minturn JE, Phillips P, Hill-Kayser CE.  Acute Toxicities and Treatment Outcomes of a Novel Craniospinal Irradiation (CSI) Technique Using Double Scattered Proton Therapy for Medulloblastoma Patients. Poster presentation at the 56th Annual Meeting of the American Society for Therapeutic Radiology and Oncology (ASTRO), San Francisco, CA, September 2014.

Fisher MJ, Widemann BC, Dombi E, Wolters P,  Cantor A, Vinks A, Perentesis J, Ullrich N, Gutmann D, Viskochil D, Tonsgard J, Korf B, Packer R, Weiss B.  Phase 2 Study of the mTOR Inhibitor Sirolimus for Progressive NF1-Associated Plexiform Neurofibromas (PN): A Neurofibromatosis Clinical Trials Consortium Study. Platform presentation at the 16th International Symposium on Pediatric Neuro-Oncology, Singapore. Neuro-Oncol, 16(Suppl 1): i129, July 2014

Fisher MJ, Marcus L, Weiss B, Kim A, Dombi E, Baldwin A, Whitcomb P, Martin S, Gillespie G, Doyle A, Widemann BC.  Selumetinib (AZD6244) hydrogen sulfate, a MEK1/2 inhibitor, in children with neurofibromatosis type 1 (NF1) and inoperable plexiform neurofibromas (PNs):  A Phase I Study.  Platform presentation at the 16th International Symposium on Pediatric Neuro-Oncology, Singapore. Neuro-Oncol, 16(Suppl 1): i129, June 2014.

Hill-Kayser CE, Paltin I, Lustig RA, Fisher MJ, Both S, Belasco JB, Cole KA, Waanders AJ, Phillips PC, Minturn JE.  Proton Radiation for Treatment of Localized Ependymoma in Children.  Poster presentation at the 16th International Symposium on Pediatric Neuro-Oncology, Singapore. Neuro-Oncol, 16(Suppl 1): i118, June 2014.

Hill-Kayser CE, Lustig RA, Minturn JE, Both Stefan, Waanders AJ, Belasco JB, Armstrong C, Phillips PC, Fisher MJ.  Outcomes after Proton Radiotherapy (RT) for Infratentorial Brain Tumors in Infants and Very Young Children.  Poster presentation at the 16th International Symposium on Pediatric Neuro-Oncology, Singapore. Neuro-Oncol, 16(Suppl 1): i118, June 2014.

Fisher MJ, Levin MH, Armstrong GT, Broad JH, Zimmerman R, Bilaniuk LT, Feygin T, Liu GT.  Optic Nerve Tortuosity in Neurofibromatosis Type 1 and Risk of Optic Pathway Glioma Development.  Poster presentation at the 16th International  Symposium on Pediatric Neuro-Oncology, Singapore. Neuro-Oncol, 16(Suppl 1): i62, June 2014.

Paltin I, Hill-Kayser CE, Lustig RA, Fisher MJ, Belasco JB, Phillips PC, Cole KA, Minturn JE.  Neuropsychological functioning after proton radiation therapy for pediatric ependymoma.  Poster presentation at the 12th Annual meeting of the American Academy of Clinical Neuropsychology, New York, NY, June 2014.

Heidary G, Fisher MJ, Liu G, Ferner R, Gutmann D, Listernick R, Loguidice M, Ardern-Holmes S, Avery RA, Hammond C, Hoffman R, Hummel TR, Reginald AR, Ullrich NJ.   Visual Field Outcomes in Pediatric Patients Treated for Neurofibromatosis Type 1- associated Optic Pathway Gliomas: A Multicenter Retrospective Study.  Poster presentation at the 2014 Children’s Tumor Foundation Neurofibromatosis Conference, Washington, DC, June 2014, p.74.

Fisher MJ, Levin MH, Armstrong GT, Broad JH, Zimmerman R, Bilaniuk LT, Feygin T, Liu GT.  Risk of Optic Pathway Glioma Development in Neurofibromatosis Type 1 Patients with Optic Nerve Tortuosity or Thickness.  Poster presentation at the 2014 Children’s Tumor Foundation Neurofibromatosis Conference, Washington, DC, June  2014, p.73. (Award for Top 3 Poster).

Widemann BC, Marcus LJ, Fisher MJ, Weiss BD, Kim A, Dombi E, Baldwin A, Whitcomb P, Martin S, Gillespie A, Doyle A.  Phase I study of the MEK1/2 inhibitor selumetinib (AZD6244) hydrogen sulfate in children and young adults with neurofibromatosis type 1 (NF1) and inoperable plexiform neurofibromas (PNs).  Poster presentation at the 50th Annual Meeting of the American Society of Clinical Oncology, Chicago, IL.  J Clin Oncol, 32(5Suppl): May 2014.

Hill-Kayser CE, Paltin I, Lustig RA, Fisher MJ, Both S, Belasco JB, Cole KA, Waanders AJ, Phillips PC, Minturn JE.  Outcomes after Proton Radiotherapy for Localized Childhood Ependymoma (EP).  Poster presentation at the 50th Annual Meeting of the American Society of Clinical Oncology, Chicago, IL.  J Clin Oncol, 32(5Suppl): May 2014.

Hill-Kayser CE, Lustig RA, Minturn JE, Both S, Waanders AJ, Belasco J, Armstrong C, Phillips P, Fisher MJ.  Proton Radiation for Treatment of Infratentorial Brain Tumors in Infants and Very Young Children.  Poster presentation at the 50th Annual Meeting of the American Society of Clinical Oncology, Chicago, IL.  J Clin Oncol, 32(5Suppl): May 2014.

Levin MH, Armstrong GT, Broad JH, Zimmerman R, Bilaniuk LT, Feygin T, Liu GT, Fisher MJ.  Risk of Glioma Development in Subjects with Neurofibromatosis Type 1 without Glioma on Initial MRI.  Poster presentation at the 40th Annual North American Neuro-Ophthalmology Society (NANOS) Meeting, Rio Grande, Puerto Rico, March 2014.

2013

Weiss B, Widemann B, Perentesis J, Vinks S, Packer R, Gutmann D, Wolters P, Viskochil D, Fisher MJ.  A Phase 2 Study of the mTOR Inhibitor Sirolimus in NF1 Related Plexiform Neurofibroma.  Oral presentation at the Connective Tissue Oncology Society (CTOS) 18th Annual Meeting, New York, NY, November 2013.

Betensky M, Fisher MJ, Nance S, Weiss M, Witmer CM, Sesok-Pizzini D. Carboplatin and Vincristine Induced Hemolytic Anemia in a Pediatric Patient with an Optic Pathway Glioma. Platform presentation at the AABB Annual Meeting & CTTXPO 2013, Denver, CO, October 2013.

Karajannis MA, Fisher MJ, Milla SS, Cohen KJ, Legault G, Wisoff JH, Harter DH, Merkelson A, Bloom MC, Dhall G, Jones D, Korshunov A, Pfister S, Eberhart CG, Sievert A, Resnick A, Zagzag D, Allen JC.  Phase II Study of Sorafenib in Children with Sporadic and NF1-related Recurrent/Progressive Low-Grade Astrocytomas.  Poster presentation at the 2013 Children’s Tumor Foundation Neurofibromatosis Conference, Monterey, CA, June 2013, p.85.

de Blank PMK, Berman JI, Liu GT, Roberts TPL, Fisher MJ. Fractional Anisotropy of the Optic Radiations is Associated with Visual Acuity Loss in Optic Pathway Gliomas of Neurofibromatosis Type 1.  Platform presentation at the 2013 Children’s Tumor Foundation Neurofibromatosis Conference, Monterey, CA, June 2013, p.23.

Nguyen-Phuc AY, Khrichenko D, Feygin T, Fisher MJ, Liu GT.  Proptosis in Optic Pathway Gliomas Associated with Neurofibromatosis: Response to Chemotherapy.  Poster Presentation at the American Academy of Neurology 65th Annual Meeting, San Diego, CA, March 2013.  

Invited Lectures

2015

“Agents in Development Targeting the RAS/MAPK Pathway” - 4th International RASopathies Symposium, Seattle, WA, July 2015.

“Optic Pathway Glioma Consortium” - 2015 Children’s Tumor Foundation Neurofibromatosis Conference, Monterey, CA June 2015.

“Low Grade Glioma and Cognition in NF1” – 2015 Children’s Tumor Foundation Neurofibromatosis Conference Educational Symposium, Monterey, CA, June 2015.

“Peripheral Nerve Sheath Tumors in Neurofibromatosis Type 1” – Pediatric Grand Rounds, Rainbow Babies & Children's Hospital, Cleveland, OH, May 2015.

“Everything You Wanted to Know About NF” – Panel Discussion, Children’s Tumor Foundation 2015 NF Forum, Scottsdale, AZ, April 2015.

“Clinical Trials for NF1 and NF2” - Children’s Tumor Foundation 2015 NF Forum, Scottsdale, AZ, April 2015.

2014

“Subacute Methotrexate Neurotoxicity” – Symposium on the Neurological Complications of Brain Tumors, Children’s Hospital of Philadelphia, Philadelphia, PA (Regional conference of medical professionals. ~100 participants), October 2014.

“Plexiform Neurofibromas: Management and Update on Clinical Trials” - 2014 Neurofibromatosis Symposium, Sponsored by the NF Family Association and Children’s Tumor Foundation, Philadelphia, PA.  (Regional Conference. Patient/parent education symposium. >100 participants), June 2014.

“Plexiform Neurofibromas: Management and Update on Clinical Trials” - 2014 Neurofibromatosis Symposium, Sponsored by the NF Family Association and Children’s Tumor Foundation, Philadelphia, PA.  (Regional Conference. Patient/parent education symposium. >100 participants), May 2014.

“Late Effects” - 2014 Salzburg CHOP Pediatric Hematology & Oncology Seminar, Salzburg, Austria, May 2014.

“Lymphoma” - 2014 Salzburg CHOP Pediatric Hematology & Oncology Seminar, Salzburg, Austria, April 2014.

“Case Presentation: Optic Pathway Glioma” - 2014 Salzburg CHOP Pediatric Hematology & Oncology Seminar, Salzburg, Austria, April 2014.

“Brain Tumors” - 2014 Salzburg CHOP Pediatric Hematology & Oncology Seminar, Salzburg, Austria, April 2014.

2013

“Optic Pathway Gliomas:  The Neuro-Oncology Perspective” – Celebrating 50 Years in Oculoplastic and Orbital Surgery Conference, Philadelphia, PA, October 2013.

“Diagnosis & Management of Orbital-Temporal Plexiform Neurofibromas” – 2013 Orbital-Temporal Plexiform Neurofibroma Conference, Chantilly, VA, September 2013.

“Outcome Measures for NF1 - Associated Optic Pathway Glioma Clinical Trials” - Response Evaluation in Neurofibromatosis and Schwannomatosis (REiNS) Conference, Monterey, CA, June 2013.

“Clinical Trials for NF1 and NF2” - 2013 Neurofibromatosis Symposium, Sponsored by the NF Family Association and Children’s Tumor Foundation, Philadelphia, PA.  (Regional Conference. Patient/parent education symposium. >100 participants), April 2013.

“Plexiform Neurofibroma Clinical Trials” – CTF/NTAP NF Therapeutics Consortium Meeting, Washington, DC, April 2013.

“Optic Pathway Gliomas in NF1: The Importance of Functional Outcomes” – NCI Pediatric Oncology Branch Research Seminar Series, National Institutes of Health, Bethesda, MD, February 2013.

“Optic Pathway Gliomas in NF1: The Importance of Functional Outcomes” – NCI Pediatric Oncology Branch Research Seminar Series, National Institutes of Health, Bethesda, MD, January 2013.

Awards and Honors

2014, Top 3 Poster, Children’s Tumor Foundation Neurofibromatosis Conference

2014, Susan B. Stine Memorial Lectureship in Neurofibromatosis, Nemours/Alfred I. duPont Hospital for Children

1992-1993, Howard Hughes Medical Institute Research Fellow

1989, Sigma Xi, The Scientific Research Society

1989, Phi Beta Kappa

Editorial and Academic Positions

Editorial positions

Reviewer

Cancer Research
International J of Computer Assisted Radiology and Surgery
Journal of Blood Medicine
Journal of Cancer Survivorship: Research and Practice
Journal of Neuro-Ophthalmology
Journal of Neuro-Oncology
Journal of Pediatrics
Journal of Supportive Care in Cancer
Neuro-Oncology
Pediatric Blood & Cancer
Pediatric Emergency Care
Libertas Academica (Peer-reviewed open access journals available on world-wide web)

Academic and Institutional Committees

2011-present, Neuro-Oncology Fellowship Program, chair
2010-present, Proton Therapy Triage Committee
2009-present, Children’s Hospital of Philadelphia Affiliate Clinic of the Children's Tumor Foundation NF Clinic Network, director
2002-present, Data and Safety Monitoring Committee of the Abramson Cancer Center, Clinical Trials Scientific Review and Monitoring Committee, University of Pennsylvania

Leadership and Memberships

Memberships in Professional Organizations

International

Children's Oncology Group

 - 2012-present, CNS Committee

National

American Academy of Pediatrics

American Association for Cancer Research

American Society of Clinical Oncology

American Society of Pediatric Hematology-Oncology

DOD, CDMRP Neurofibromatosis Consortium

 - 2012-present, Steering Committee, deputy chair

 - 2011-present, Neurofibroma Committee, chair

 - 2009-present, Site Evaluation Committee, chair

 - 2009-present, Steering Committee, member

 - 2008-present, Membership Committee

 - 2006-present, Neurofibroma Committee, member

 - 2006-present, Visual Pathway Glioma Committee

Pacific Pediatric Neuro-Oncology Consortium

Pediatric Brain Tumor Consortium

Society for Neuro-Oncology