Center for Precision Medicine for High-Risk Pediatric Cancer
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The Center for Precision Medicine for High-Risk Pediatric Cancer is a single stop for children and young adults whose cancers are very difficult to treat. These cancers:
- Do not have a proven way to be treated
- Do not go away after the usual treatment
- Come back (relapse) after treatment
We have a state-of-the-art laboratory where we study your child’s tumor to find the genetic changes that make the cancer so tough. We learn everything about your child’s cancer journey. Then we take this knowledge and create a very specific treatment strategy for your child.
We know you and your child have already been through a great deal. Our team of experts will be by your side and support your family’s needs every step of the way.
How we serve you
The center offers your child a world-class, one-stop Cancer Precision Medicine Clinic where we bring together specialists in oncology, tumor sequencing, surgery, radiology, pathology and radiation oncology. In partnership with CHOP’s Developmental Therapeutics Program, we conduct clinical trials for new precision therapies supported by these precision diagnostics. Our patients have access to clinical trials that are appropriate for them.
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Advanced Pediatric Thyroid Cancer Therapeutics Clinic -
AYA Oncology Program -
Alex Scott Day Hospital -
Bone and Soft Tissue Tumor Program -
Immunotherapy Program -
Cellular Therapy and Transplant -
Developmental Therapeutics Program -
Leukemia and Lymphoma Program -
Oncology Psychosocial Services Program -
Brain Tumor Program -
Proton Therapy Center -
Surgical Oncology Program -
Pediatric Urologic Oncology -
Refractory Neuroblastoma Program -
Relapsed Leukemia and Lymphoma Program -
Solid Tumor Program -
Very Rare Malignant Tumors Program
Conditions we treat
We treat every type of cancer, including cancers that are very rare.
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Acute lymphoblastic leukemia (ALL) -
Acute myelogenous leukemia (AML) -
Brain tumors -
Central nervous system (CNS) germ cell tumors -
Chondrosarcoma -
Chronic myelogenous leukemia (CML) -
Differentiated thyroid cancer -
Ewing sarcoma -
Hepatoblastoma (liver cancer) -
Hodgkin lymphoma -
Juvenile myelomonocytic leukemia (JMML) -
Medullary thyroid cancer -
Neuroblastoma -
Non-Hodgkin lymphoma -
Osteosarcoma (bone cancer) -
Pediatric leukemias -
Pediatric testicular tumors -
Relapsed or refractory neuroblastoma -
Retinoblastoma (eye cancer) -
Rhabdomyosarcoma -
Skin cancer -
Soft tissue sarcomas -
Wilms tumor (kidney tumor)
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Why choose the Center for Precision Medicine for High-Risk Pediatric Cancer
Our precision medicine team for pediatric cancer has two areas of focus:
- Profiling each patient’s cancer to identify unique vulnerabilities and prognostic or therapeutic markers
- Structuring treatment based on an individual patient's identified risk and genetic targets
![An elementary age girl talking to medical doctor wearing headscarf receiving infusion.](/sites/default/files/styles/landscape_150_3x2_160x107_1x/public/2024-05/Photo-ONC-Team2-2624X1720-v01.jpg?itok=kN37Jdi9)
Meet your team
Your child will be cared for by one of the most accomplished teams of childhood cancer experts in the world. We work together to give your child the highest level of care.
![Smiling CHOP patient holding shopping bag](/sites/default/files/styles/square_100_160x160_1x/public/2024-06/Photo-Foundation-Shop-for-Chop-Become-Partner-Hero-2624x1720-v01.jpg?h=b840d9cf&itok=b_4zmn0L)
Our research
Our physician-scientists are not only experts in delivering treatment but are involved in the development of new ways to treat these diseases more safely, effectively and with fewer side effects. The team members are leaders in international clinical trials for solid tumors, leukemia and brain tumors.
![Father and son smiling together looking at a laptop computer.](/sites/default/files/styles/landscape_150_3x2_160x107_1x/public/2024-03/Photo-Default-PatientResources-Father-Son-Laptop-2624x1720-v01.jpg?itok=yK4m4ZfQ)
Center for Precision Medicine for High-Risk Pediatric Cancer resources
We have created resources to help you find answers to your questions and feel confident with the care you are providing your child at home.
![Medical Professionals conferring together](/sites/default/files/styles/landscape_150_3x2_160x107_1x/public/2024-03/Photo-Default-ProfessionalResources-Physician-Talking-Nurse-Computer-2624x1720-v01.jpg?h=9530173b&itok=rBxSFlL1)
Resources for professionals
Everything you need to support your patient’s health, created and updated by our CHOP community of experts
Give to the Cancer Center
There are many ways to support CHOP's Cancer Center. A gift of any size can help us make life-changing breakthroughs and advance our work for children everywhere.
![Child with cancer in mint green tshirt being held in arms by her mother.](/sites/default/files/styles/landscape_150_3x2_160x107_1x/public/2024-05/Photo-ONC-donate3-2624X1720-v01.jpg?itok=WTDqUCki)