Background

Dr. Foglia performs clinical research related to neonatal resuscitation and respiratory management. Her research aims to characterize the epidemiology of neonatal resuscitation, to improve monitoring and clinical performance during resuscitation, and to identify interventions to prevent mortality and long-term morbidity in high-risk infants.

Dr. Foglia is the Director of Neonatal Resuscitation and Simulation at the Hospital of the University of Pennsylvania, and she facilitates simulation-based resuscitation training for the pediatric residents. She is a hospital-based Neonatal Resuscitation Program (NRP) instructor, and she is a member of the American Heart Association Get With the Guidelines- Resuscitation Pediatric Taskforce.

Education and Training

Medical School

MD - Washington University School of Medicine, St. Louis, MO

Internship

Pediatrics - The Children's Hospital of Philadelphia, Philadelphia, PA

Residency

Pediatrics - The Children's Hospital of Philadelphia, Philadelphia, PA

Fellowship

Neonatology - The Children's Hospital of Philadelphia, Philadelphia, PA

Board Certification

Neonatal-Perinatal Medicine
Pediatrics

Graduate Degree

MS in Clinical Epidemiology (MSCE) - University of Pennsylvania, Philadelphia, PA
MA in Biology - Washington University School of Medicine, St. Louis, MO

Titles and Academic Titles

Attending Neonatologist

Assistant Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania

Departments and Services

Research Interests

Delivery room management
Neonatal resuscitation epidemiology
Respiratory management of preterm infants
Intubation safety and education

Publications

Papers

2019

Foglia EE, Ades A, Hedrick HL, Rintoul N, Munson DA, Moldenhauer J, Gebb J, Serletti B, Chaudhary A, Weinberg DD, Napolitano N, Fraga MV, Ratcliffe SJ. Initiating resuscitation before umbilical cord clamping in infants with congenital diaphragmatic hernia: a pilot feasibility trial. Arch Dis Child Fetal Neonatal Ed. 2019 Aug 28. pii: fetalneonatal-2019-317477. doi: 10.1136/archdischild-2019-317477. [Epub ahead of print]

Umoren RA, Sawyer TL, Ades A, DeMeo S, Foglia EE, Glass K, Gray MM, Barry J, Johnston L, Jung P, Kim JH, Krick J, Moussa A, Mulvey C, Nadkarni V, Napolitano N, Quek BH, Singh N, Zenge JP, Shults J, Nishisaki A; National Emergency Airway Registry for Neonates (NEAR4NEOS) Investigators. Team Stress and Adverse Events during Neonatal Tracheal Intubations: A Report from NEAR4NEOS. Am J Perinatol. 2019 Jul 31. doi: 10.1055/s-0039-1693698. [Epub ahead of print]

Root L, van Zanten HA, den Boer MC, Foglia EE, Witlox RSGM, Te Pas AB. Improving Guideline Compliance and Documentation Through Auditing Neonatal Resuscitation. Front Pediatr. 2019 Jul 16;7:294. doi: 10.3389/fped.2019.00294. eCollection 2019.

Foglia EE, Carper B, Gantz M, DeMauro SB, Lakshminrusimha S, Walsh M, Schmidt B; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Association between Policy Changes for Oxygen Saturation Alarm Settings and Neonatal Morbidity and Mortality in Infants Born Very Preterm. J Pediatr. 2019 Jun;209:17-22.e2. doi: 10.1016/j.jpeds.2019.01.048. Epub 2019 Apr 5.

Dekker J, van Kaam AH, Roehr CC, Flemmer AW, Foglia EE, Hooper SB, Te Pas AB. Stimulating and maintaining spontaneous breathing during transition of preterm infants. Pediatr Res. 2019 Jun 19. doi: 10.1038/s41390-019-0468-7. [Epub ahead of print] Review.

den Boer MC, Houtlosser M, Foglia EE, Davis PG, van Kaam AH, Kamlin COF, Schmölzer GM, de Vries MC, Te Pas AB. Deferred consent for the enrolment of neonates in delivery room studies: strengthening the approach. Arch Dis Child Fetal Neonatal Ed. 2019 May 9. pii: fetalneonatal-2018-316461. doi: 10.1136/archdischild-2018-316461. [Epub ahead of print] No abstract available.

Ozawa Y, Aades A. Foglia E. DeMeo S, Barry J, Sawyer T, Singh N, Glass K, Jung P, Quek B, Johnston L, Kim J, Napolitano N, Shults J, Nadkarni V, Nishisaki A for the Near4NEOS Investigators. Premedication with neuromuscular blockade and sedation during neonatal intubation is associated with fewer adverse events. J Perinatol. 2019 Apr 2. doi: 10.1038/s41372-019-0367-0. [Epub ahead of print]

Kirpalani H, Ratcliffe SJ, Keszler M, Davis PG, Foglia EE, Te Pas A, SAIL Site Investigators, et al. Effect of Sustained Inflations vs Intermittent Positive Pressure Ventilation on Bronchopulmonary Dysplasia or Death Among Extremely Preterm Infants: The SAIL Randomized Clinical Trial. JAMA. 2019 Mar 26;321(12):1165-1175. doi: 10.1001/jama.2019.1660. PMID: 30912836

Sawyer T, Foglia EE. Resuscitation Quality Metrics for the Newly Born. Am J Perinatol. 2019 Mar 1. doi: 10.1055/s-0039-1681098. [Epub ahead of print]

Sawyer T, Foglia EE, Ades A, Moussa A, Napolitano N, Glass K, Johnston L, Jung P, Singh N, Quek BH, Barry J, Zenge J, DeMeo SD, Brei B, Krick J, Kim JH, Nadkarni V, Nishisaki A. Incidence, impact and indicators of difficult intubations in the neonatal intensive care unit: a report from the National Emergency Airway Registry for Neonates. Arch Dis Child Fetal Neonatal Ed. 2019 Feb 22;. PMID: 30796059

Sawyer T, Foglia E, Ades A, Moussa A, Napolitano N, Glass K, Johnston L, Jung P, Singh N, Quek B, Nadkarni V, Nishisaki A for the NEAR4NEOS investigators. Incidence and Indicators of Difficult Intubations in the NICU. Arch Dis Child Fetal Neonatal Ed. Feb. 2019.

2018

Foglia EE, Ades A, Sawyer T, Glass KM, Singh N, Jung P, Quek BH, Johnston LC, Barry J, Zenge J, Moussa A, Kim JH, DeMeo SD, Napolitano N, Nadkarni V, Nishisaki A; NEAR4NEOS Investigators. Neonatal Intubation Practice and Outcomes: An International Registry Study. Pediatrics. 2018 Dec 11. pii: e20180902. [Epub ahead of print]

den Boer MC, Houtlosser M, Foglia EE, Tan RNGB, Engberts DP, Te Pas AB. Benefits of recording and reviewing neonatal resuscitation: the providers' perspective. Arch Dis Child Fetal Neonatal Ed. 2018 Dec 1. pii: fetalneonatal-2018-315648. [Epub ahead of print]

Fishman CE, Weinberg DD, Murray A, Foglia EE. Accuracy of real-time delivery room resuscitation documentation. Arch Dis Child Fetal Neonatal Ed. 2018 Nov 24. pii: fetalneonatal-2018-315723. doi: 10.1136/archdischild-2018-315723. [Epub ahead of print] PMID: 30472661

Sillers L, Handley SC, James JR, Foglia EE. Pulseless Electrical Activity Complicating Neonatal Resuscitation. Neonatology. 2018 Oct 23;115(2):95-98. doi: 10.1159/000493357. [Epub ahead of print]

Bonafide CP, Localio AR, Ferro DF, Orenstein EW, Jamison DT, Lavanchy C, Foglia EE. Accuracy of Pulse Oximetry-Based Home Baby Monitors. JAMA. 2018 Aug 21;320(7):717-719. doi: 10.1001/jama.2018.9018.

Pouppirt NR, Nassar R, Napolitano N, Nawab U, Nishisaki A, Nadkarni V, Ades A, Foglia EE. Association Between Video Laryngoscopy and Adverse Tracheal Intubation-Associated Events in the Neonatal Intensive Care Unit. J Pediatr. 2018 Jul 3. pii: S0022-3476(18)30759-5. doi: 10.1016/j.jpeds.2018.05.046. [Epub ahead of print]

Jensen EA, Foglia EE, Dysart KC, Simmons RA, Aghai ZH, Cook A, Greenspan JS, DeMauro SB. Adverse effects of small for gestational age differ by gestational week among very preterm infants. Arch Dis Child Fetal Neonatal Ed. 2018 May 5. pii: fetalneonatal-2017-314171. doi: 10.1136/archdischild-2017-314171. [Epub ahead of print]

Pouppirt NR, Foglia EE, Ades A. A video is worth a thousand words: innovative uses of videolaryngoscopy. Arch Dis Child Fetal Neonatal Ed. 2018 May 4. pii: fetalneonatal-2017-314288. doi: 10.1136/archdischild-2017-314288. [Epub ahead of print] No abstract available.

Foglia EE, Te Pas AB. Effective ventilation: The most critical intervention for successful delivery room resuscitation. Semin Fetal Neonatal Med. 2018 Apr 17. pii: S1744-165X(18)30065-9. doi: 10.1016/j.siny.2018.04.001. [Epub ahead of print] Review.

Huberts TJP, Foglia EE, Narayen IC, van Vonderen JJ, Hooper SB, Te Pas AB. The Breathing Effort of Very Preterm Infants at Birth. J Pediatr. 2018 Jan 12. pii: S0022-3476(17)31501-9. doi: 10.1016/j.jpeds.2017.11.008. [Epub ahead of print]. PMID: 29336795

den Boer MC, Houtlosser M, van Zanten HA, Foglia EE, Engberts DP, Te Pas AB. Ethical dilemmas of recording and reviewing neonatal resuscitation. Arch Dis Child Fetal Neonatal Ed. 2018 Jan 20. pii: fetalneonatal-2017-314191. doi: 10.1136/archdischild-2017-314191. [Epub ahead of print] Review. PMID: 29353257

2017

Jensen EA, Foglia EE, Dysart KC, Aghai ZH, Cook A, Greenspan JS, DeMauro SB. Car Seat Tolerance Screening in the Neonaal Intensive Care Unit: Failure Rates, Risk Factors, and Adverse Outcomes. J Pediatr. 2017 Dec 18. pii: S0022-3476(17)31503-2. doi: 10.1016/j.jpeds.2017.11.010. [Epub ahead of print]

Foglia EE, Jensen EA, Kirpalani H. State of the Art Review: Delivery room interventions to prevent bronchopulmonary dysplasia in extremely preterm infants. J Perinatol. 2017 Nov;37(11):1171-1179. doi: 10.1038/jp.2017.74. Epub 2017 Jun 1.

Niles DE, Cines C, Insley E, Foglia EE, Elci OU, Skåre C, Olasveengen T, Ades A, Posencheg M, Nadkarni VM, Kramer-Johansen J. Incidence and characteristics of positive pressure ventilation delivered to newborns in a US tertiary academic hospital. Resuscitation. 2017 Apr 11. pii: S0300-9572(17)30135-1. [Epub ahead of print]

Sawyer T, Foglia EE, Hatch LD, Moussa A, Ades A, Johnston L, Nishisaki A. Improving neonatal intubation safety: A journey of a thousand miles. J Neonatal Perinatal Med. 2017 Apr 8. [Epub ahead of print]

Flannery DD, Foglia EE. The contributions of red blood cell transfusion and severe anemia in necrotizing enterocolitis: causes or confounders? J Perinatol. 2017 Mar 23. [Epub ahead of print]

Foglia EE, Owen LS, Keszler M, Davis PG, Kirpalani H. Obtaining informed consent for delivery room research: the investigators' perspective. Arch Dis Child Fetal Neonatal Ed. 2017 Jan;102(1):F90-F91. doi: 10.1136/archdischild-2016-310934. Epub 2016 Aug 11.

Foglia EE, Langeveld R, Heimall L, Deveney A, Ades A, Jensen EA, Nadkarni VM: Incidence, characteristics, and survival following cardiopulmonary resuscitation in the quaternary neonatal intensive care unit. Resuscitation. 2017 Jan;110:32-36. doi: 10.1016/j.resuscitation.2016.10.012. Epub 2016 Oct 27.

2016

Foglia EE, Whyte RK, Chaudhary A, Mott A, Chen J, Propert KJ, Schmidt B: The Effect of Skin Pigmentation on the Accuracy of Pulse Oximetry in Infants with Hypoxemia. J Pediatr. 2016 Dec 9. pii: S0022-3476(16)31272-0. doi: 10.1016/j.jpeds.2016.11.043. [Epub ahead of print]

Tramper J, Zhang H, Foglia EE, Dysart KC, Padula MA, Sullivan KV, Jensen EA.: The association between positive tracheal aspirate cultures and adverse pulmonary outcomes in preterm infants with severe bronchopulmonary dysplasia. Am J Perinatol. 2016 Jun 10. [Epub ahead of print]

2015

Foglia EE, DeMauro SB, Dysart K, Kirpalani H. When has enough evidence accumulated to change neonatal practice? Semin Fetal Neonatal Med. 2015 Dec;20(6):424-30. doi: 10.1016/j.siny.2015.09.003. Epub 2015 Oct 4.

Foglia E, Ades A, Napolitano N, Leffelman J, Nadkarni V, Nishisaki A.: Factors associated with adverse events during tracheal intubation in the NICU. Neonatology 108: 23-29, 2015.

Foglia EE, Owen LS, Thio M, Ratcliffe SJ, Lista G, Te Pas A, Hummler H, Nadkarni V, Ades A, Posencheg M, Keszler M, Davis P, Kirpalani H: Sustained Aeration of Infant Lungs (SAIL) trial: study protocol for a randomized controlled trial. Trials 16(1): 601, Dec 2015.

Foglia EE, Nolen TL, DeMauro SB, Das A, Bell EF, Stoll BJ, Schmidt B; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Short-term Outcomes of Infants Enrolled in Randomized Clinical Trials vs Those Eligible but Not Enrolled. JAMA. 2015 Jun 16;313(23):2377-2379. doi: 10.1001/jama.2015.5734. No abstract available. PMID: 26080344

2014

Foglia EE, Kirpalani H, DeMauro SB. Long-Term Respiratory Morbidity in Preterm Infants: Is Noninvasive Support in the Delivery Room the Solution? J Pediatr. 2014 May 16. pii: S0022-3476(14)00347-3. doi: 10.1016/j.jpeds.2014.04.018. [Epub ahead of print] Read the abstract.

2013

Foglia E, Patel J, Niles D, Aasland PH, Nadkarni V, Ades A. Provider Adherence to Neonatal Resuscitation Program Recommendations for Coordinated Neonatal Chest Compressions and Ventilations. Analg Resusc. 2013 Jul 25;SuppI1. PMID: 24199206

Books

Chapters

2018

Foglia EE, Wyckoff MH: Delivery Room Resuscitation of the Newborn Infant. In: Rudolph's Pediatrics 23rd Edition. Kline MW, eds (eds.). McGraw-Hill 2018.

2011

Foglia E, Kim J. Fever of unknown origin. In Florin TA, Ludwig S, (Eds). Netter's Pediatrics. Elsevier, Philadelphia, 2011.

Posters and Presentations

2019

Foglian E, Ades A, Hedrick H, Rintoul N, Munson D, Moldenhauer J, Gebb J, Chaudhary A, Weinberg D, Ratcliffe S: Initiating Resuscitation Before Umbilical Cord Clamping in Infants with Congenital Diaphragmatic Hernia: A Pilot Clinical Trial. Pediatric Academic Societies Annual Meeting, Baltimore MD April 2019 Notes: Poster Symposium.

Foglia EE, te Pas AB, Kirpalani H, Davis PG, Thio M, Hummler H, Lista G, Cavigioli F, Schmölzer G, Ratcliffe SJ: Respiratory Function Measurements of Participants in the Sustained Aeration of Infant Lungs (SAIL) Randomized Trial. Pediatric Academic Societies Annual Meeting, Baltimore MD April 2019 Notes: poster.

Foglia EE, te Pas AB, Kirpalani H, Davis PG, Owen L, van Kaam A, Onland W, Keszler M, Schmolzer G, Hummler H, Lista G, Dani C, Bastrenta P, Localio R, Ratcliffe SJ: Sustained Inflation vs. Intermittent Positive Pressure Ventilation or Continuous Positive Airway Pressure during Neonatal Resuscitation of Preterm Infants: An Updated Meta-analysis. Pediatric Academic Societies Annual Meeting, Baltimore PD April 2019 Notes: Poster.

2017

Foglia EE, Roberts R, Stoller J, Davis P, Haslam R, Schmidt B: Does the efficacy of prophylactic indomethacin depend on the baseline risk of severe intraventricular hemorrhage in extremely low birth weight infants? Pediatric Academic Societies Annual Meeting, San Francisco CA May 2017 Notes: Poster presentation.

Foglia EE, Carper B, Gantz M, Demauro SB, Lakshminrusimha S, Walsh M, Schmidt B: Association between changes in pulse oximetry alarm policies for extremely preterm infants and neonatal mortality or morbidity. Pediatric Academic Societies Annual Meeting, San Francisco CA May 2017 Notes: Poster presentation.

Foglia EE, Ades A, Sawyer TL, Glass K, Singh N, Jung P, Quek BH, Johnson L, Napolitano N, Nadkarni V, Nishisaki A: Landscape of Neonatal Intubation Safety from the International NEAR4NEOS registry. Pediatric Academic Societies Annual Meeting, San Francisco CA May 2017 Notes: Poster presentation.

Invited Lectures

2019

Foglia EE. "Initiating Resuscitation Before Umbilical Cord Clamping in Infants with Congenital Diaphragmatic Hernia: A Pilot Clinical Trial." Poster Presentation. Pediatric Academic Societies (PAS) 2019 Meeting. April 27-30, Baltimore, MD. Invited Lectures 2019

Foglia EE. "Resuscitation on the cord for infants with CDH," Dresden Symposium on Delivery Room Management, Asphyxia, Hypothermia, and Stem Cell Research, Dresden Germany. Mar, 2019.

Foglia EE. "Handle with Care: Monitoring Preterm Infants During Neonatal Transition," Virtua Vorhees Hospital, Vorhees NJ. Feb, 2019.

2018

Foglia EE. "Gaining Clarity During Neonatal Resuscitation", Changing Seasons in Neonatology Conference, Oklahoma City OK. Nov, 2018.

Foglia EE. "Sustained Inflation for Lung Aeration," Annual Symposium on Neonatal Advances: Update on Delivery Room Management, Farmington CT. Oct, 2018.

Foglia EE. "Managing the Team in the Delivery Room", Ipokrates Foundation Clinical Seminar: Evidence-based Cardio-respiratory care of the Newborn Infant, Oxford UK. Sep, 2018.

Foglia EE. "When has Enough Evidence Accumulated to Make a Standard of Care?", Ipokrates Foundation Clinical Seminar: Evidence-based Cardio-respiratory Care of the Newborn Infant, Oxford UK. Sep, 2018.

Foglia EE. "Handle With Care: Monitoring Preterm Infants During Neonatal Transition", Pediatric Grand Rounds, Christiana Care Hospital, Newark DE. Aug, 2018.

Foglia EE. "Delivery room intubation: Insight from a neonatal airway registry", Canadian Pediatric Society Annual Meeting, Quebec City Canada. May, 2018.

Foglia EE. "The Dilemma of Informed Consent for Delivery Room Resuscitation Research", Children's Hospital of Philadelphia Neonatology Clinical Research Symposium, Philadelphia PA. May, 2018.

Foglia EE. "Delivery Room Resuscitation Research: Challenges and Opportunities", NRP Resuscitation Club, Canadian Pediatric Society Annual Meeting, Quebec City Canada. May, 2018.

Foglia EE. "To cut and run or take the CHOP route? Resuscitation on the cord for infants with CDH", The Royal Children's Hospital Parkville Neonatal Grand Rounds, Melbourne Australia. Apr, 2018.

2017

Foglia EE. "Neonatal Intubation: View from an International Registry", Hot Topics in Neonatology, Washington DC. Dec, 2017.

Foglia EE. "Delivery Room of the Future", Neonatal Resuscitation Program Current Issues, American Academy of Pediatrics Annual Meeting, Chicago IL. Sep, 2017.

Foglia EE. "Monitor the monitors: Novel methods to identify providers' attention patterns during neonatal resuscitation," 5th International Neonatal Resuscitation Research Workshop, Napa Valley CA. May, 2017.

Foglia EE. "Gaining Objectivity in Neonatal Resuscitation: Lessons Learned through Video Recording," Philadelphia Perinatal Society/Delaware Valley Association of Neonatal Nurses Annual Meeting, Philadelphia PA. Apr, 2017.

Foglia EE. "Delayed Cord Clamping After Birth: Evidence and Recommendations," Grandview Hospital, Sellersville PA. Apr, 2017.

Foglia EE. "Handle with care: Monitoring preterm infants during neonatal resuscitation", Chester County Hospital Optimizing Neonatal Care Lecture Series, West Chester PA. Jan, 2017.

Awards and Honors

2019, CHOP Early Career Honor Roll
2016 & 2018, CHOP Early Career Faculty Honor Roll
2016 & 2018, Loan Repayment Program Recipient, National Institutes of Health
2015, Neonatal Resuscitation Program Young Investigator Award
2015, Society for Pediatric Research Junior Investigator Coaching Program and Travel Award
2014, Patient-Oriented Research Award, The Children's Hospital of Philadelphia Research Poster Day

Editorial and Academic Positions

Academic and Institutional Committees

2017-present, Chair, Neonatal Scientific Review Committee
2016, Director, Neonatal Resuscitation and Simulation, Hospital of the University of Pennsylvania
2015-present, Director, Neonatal resuscitation audiovisual review program, Hospital of the University of Pennsylvania
2014-present, Neonatal Codes Committee, Intensive Care Unit, Hospital of the University of Pennsylvania

Leadership and Memberships

Memberships in Professional Organizations
International

2016-present, European Society of Pediatric Research
2015-present, International Liaison Committee on Resuscitation (ILCOR) Neonatal Delegation (Evidence Review, 2015-2020 cycle)

National

2015-present, Society for Pediatric Research
2014-present, American Heart Association Get with the Guidelines — Resuscitation (Pediatric Research Task Force Member)
2012-present, American Academy of Pediatrics
 - 2019-present, NRP Steering Committee
 - 2012-present, Instructor, Neonatal Resuscitation Program
 - 2006-present, Neonatal Resuscitation Program