Sabrina Gmuca, MD, MSCE

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Sabrina Gmuca, MD, MSCE, is Director of The Center for Amplified Musculoskeletal Pain Syndrome and attending rheumatologist in the Division of Rheumatology at Children's Hospital of Philadelphia.

Areas of Expertise: Rheumatology, Amplified Musculoskeletal Pain Syndrome
Locations: Main Hospital

Appointments and Referrals: 1-800-TRY-CHOP (1-800-879-2467)

Education and Training

Medical School

MD - State University of New York Downstate, Brooklyn, NY


Pediatrics - New York University, New York, NY


Pediatrics - New York University, New York, NY


Pediatric Rheumatology - Children's Hospital of Philadelphia, Philadelphia, PA

Board Certification

American Board of Pediatrics
Pediatric Rheumatology

Graduate Degree

MS in Clinical Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, PA

Titles and Academic Titles

Attending Physician

Director, Center for Amplified Musculoskeletal Pain Syndrome

Assistant Professor, Perelman School of Medicine at the University of Pennsylvania

Departments and Services




Gmuca S, Yu J, Weiss PF, Treat JR, Sherry DD: Erythema Ab Igne in an adolescent with chronic pain: An alarming cutaneous eruption from heat exposure. Pediatr Emerg Care 36(4): e236-e238, April 2020.

Sherry DD, Sonagra M, Gmuca S: The Spectrum of Pediatric Amplified Musculoskeletal Pain Syndrome. Pediatric Rheumatology 2020 Notes: in press.


Gmuca S, Hardy DI, Narula S, Stoll S, Harris J, Zhao Y, Xiao R, Weiss PF, Waldman AT, Gerber JS: Validation of claims-based diagnoses of adult and pediatric neuromyelitis optica spectrum disorder and variations in diagnostic evaluation and treatment initiation. Mult Scler Relat Disord 1(37): 101488, November 2019.

Gmuca S, Xiao R, Sherry DD. Patient-proxy agreement on health-related quality of life in juvenile fibromyalgia syndrome. Pediatric Rheumatol Online J. 2019 May 9;17(1):21. doi: 10.1186/s12969-019-0320-y. PMCID: PMC 6507148

Gmuca S, Xiao R, Urquhart A, Weiss PF, Gillham JE, Ginsburg KR, Sherry DD and Gerber JS. The Role of Patient and Parental Resilience in Adolescents with Chronic Musculoskeletal Pain. J Pediatr. April. 2019. pii: S0022-3476(19)30293-8. doi: 10.1016/j.jpeds.2019.03.006.


Kushner CJ, Tarazi M, Gaffney RG, Feng R, Ardalan K, Brandling-Bennett HA, Castelo-Soccio L, Chang JC, Chiu YE, Gmuca S et al. Evaluation of the reliability and validity of the Cutaneous Lupus Erythematosus Disease Area and Severity Index (CLASI) in pediatric cutaneous lupus among pediatric dermatologists and rheumatologists. Br J Dermatol. Jul. 2018.

Gmuca S, Xiao R, Weiss PF, Sherry DD, Knight AK, Gerber JS. Opioid Prescribing and Polypharmacy in Children with Chronic Musculoskeletal Pain. Pain Med. 2018 Jun. doi: 10.1093/pm/pny116.

Gmuca S, Xiao R, Weiss PF, Waldman AT, Gerber JS. Use of rituximab and risk of re-hospitalization for children with neuromyelitis optica spectrum disorder. Multiple Sclerosis and Demyelinating Disorders. 2018;3(1):3.

Gmuca S, Yu J, Weiss PF, Treat JR, Sherry DD. Erythema Ab Igne in an Adolescent with Chronic Pain: An Alarming Cutaneous Eruption from Heat Exposure. Pediatr Emerg Care. Mar 12, 2018.  doi: 10.1097/PEC.0000000000001460


Gmuca S, Sherry DD. Fibromyalgia: Treating Pain in the Juvenile Patient. Paediatr Drugs. 2017 Aug; 19(4):325-338. PMCID: PMC5656276

Gmuca S, Lieberman SM, Mehta J. Neuromyelitis Optica Spectrum Disorder and Sjögren Syndrome: More Common Than Previously Thought? J Rheumatol. 2017; 44(6):959-60.

Gmuca S, Xiao R, Brandon TG, Pagnini I, Wright TB, Beukelman T, Morgan EM, Weiss PF. Multicenter inception cohort of enthesitis-related arthritis: variation in disease characteristics and treatment approaches. Arthritis Res Ther. 2017; 19:84.


Gmuca S, Boos MD, Treece A, et al. Degos disease mimicking primary vasculitis of the CNS. Neurol Neuroimmunol Neuroinflammation 2016 3: e206. PMCID: PMC4747475.


Gmuca S, Weiss PF. Pediatric Rheumatology: Evaluation and Treatment of Childhood Enthesitis-Related Arthritis. Curr Treat Options in Rheum. 2015 Sep 29:1-15. PMCID: PMC4725597.

Williamson KA, Gmuca S, Rosman EC, Thomas P. Infective Endocarditis and Aortic Valve Abscess in an Infant. Pediatr Emerg Care. 2015 Sep; 31(9):654-5. PMCID: 26335231.

Gmuca S, Weiss PF. Juvenile Spondyloarthritis. Curr Opin Rheumatol 2015. Jul; 27(4):364-72. PMCID: PMC4486266.


Gmuca S, Pouppirt N, Gold-von Simson G. Piperacillin-Tazobactam Toxicity Questions the Need for Pediatric Adverse Event Profiling. Pediatr Endocrinol Rev. 2017 Jun;14(Suppl 2):454-461.



Sherry DD, Gmuca S. : Somatic Symptom Disorder and the Physician's Role. JAMA Pediatr May 2020.

Muhly W, Man J, Gmuca S: Pain management in pediatric orthopedics. In Lovell and Winter's Pediatric Orthopaedics, 8e. Weinstein SL and Flynn JM, Lippincott Williams & Williams (eds.). 2020.


Gmuca S, Weiss PF, Waldman A. Sarcoid with optic nerve presentation. In: Waubant E, Lotze T (eds.). Pediatric Demyelinating Diseases of the Central Nervous System and Their Mimics: A case-based clinical guide. Springer, 2017

Posters and Presentations


Gmuca S, Sonagra M, Xiao R, Thomas NH, Miller KS, Young JF, Weiss PF, Sherry DD, Gerber JS: Patient-Proxy Agreement on Mental Health and Neuropsychological Symptoms Among Youth with Juvenile Fibromyalgia Syndrome [abstract]. Arthritis Rheumatol 72(suppl 4), May 2020 Notes: oral abstract cancelled due to COVID-19.

Greenberg B, Sonagra M, Priestley D, Pianucci L, Gmuca S: Disordered Eating Among Youth with Chronic Musculoskeletal Pain: The Experience of a Pediatric Rheumatology Pain Clinic. Association for Psychological Science, Chicago, IL. May 2020 Notes: e-abstract due to COVID-19.

Gmuca S, Sonagra M, Xiao R, Thomas NH, Miller KS, Young JF, Weiss PF, Sherry DD, Gerber JS: Suicidality in Juvenile Fibromyalgia Syndrome: Risk and Resilience. International Association for the Study of Pain World Congress on Pain, Amsterdam, Netherlands 2020 Notes: e-poster due to COVID-19 and meeting rescheduled for 2021


Gmuca S, Sonagra M, Xiao PhD, Miller KS, Thomas NH, Weiss PF, Sherry DD, Gerber JS: Subjective and objective dyscognition in adolescents with juvenile fibromyalgia syndrome. Poster presentation, American College of Rheumatology Conference, Atlanta GA. November 2019.


Gmuca S, Urquhart A, Weiss PF, Gerber JS, Sherry DD (2018). The Role of Patient and Parental Resilience in Amplified Musculoskeletal Pain Syndrome. Poster presented at: American College of Rheumatology Conference, Chicago IL.

Gmuca S, Urquhart A, Sherry DD (2018). Patient-Proxy Agreement on Health-Related Quality of life in Juvenile Fibromyalgia Syndrome. Poster presented at: American College of Rheumatology Conference, Chicago IL.


Gmuca S, Tress JL, Mosby J, Richardson LP, Sherry DD (2017). Presenting Manifestations of Amplified Musculoskeletal Pain Syndromes in Males versus Females. Poster presented at: CHOP Research Poster Day, Philadelphia, PA; PRSYM, Houston, TX; and RRW, St. Louis Mo.

Gmuca S, Waldman AT, Weiss PF, Gerber JS (2017). Use of Rituximab and Risk of Re-hospitalization for Children with Neuromyelitis Optica Spectrum Disorder. Poster presented at: CHOP Research Poster Day, Philadelphia PA and PRSYM, Houston TX.

Gmuca S, Xiao R, Knight A, Sherry DD, Weiss PF, Gerber JS (2017). Curbing the Opioid Epidemic: Predictors of Opioid Use in Juvenile Fibromyalgia Syndrome. Annual American College of Rheumatology Conference, San Diego, CA.


Gmuca S, Xiao R, Gerber JS, Weiss PF (2016). Neuromyelitis Optica: Patient Characteristics and Treatment Patterns Among Rheumatologists versus Non-Rheumatologists. Poster presented at: Annual College of Rheumatology Conference, Washington DC.

Lectures by Invitation


Gmuca S. “Amplified Musculoskeletal Pain Syndrome.” Reading Hospital Pediatric Grand Rounds, Reading, PA. 2019.


Gmuca S. "Overview of Pediatric Rheumatology Lecture," Cooper Medical School of Rowan University, Camden NJ

Awards and Honors

2020 Rheumatology Research Foundation Investigator Award
2019, Rheumatology Research Foundation K Bridge Award
2018, Thrasher Early Career Award
2017, Distinguished Research Trainee Award (Physician Fellow Category), Children's Hospital of Philadelphia
2016, American College of Rheumatology FIT (Fellows in Training) Annual Meeting Scholarship
2016, Children’s Hospital of Philadelphia Research Poster Day: Patient-Oriented Research Award
2016, Rheumatology Research Foundation: Pediatric Research Award
2015, American College of Rheumatology FIT (Fellows in Training) Annual Meeting Scholarship
2013, PGY-2 of the Year Award

Leadership and Memberships

2020-present, Vice Chair of the Early Investigator Committee, Childhood Arthritis and Research Alliance (CARRA)

2019-present, International Association for the Study of Pain (IASP), Pain in Childhood Special Interest Group (Member)

2019-present, Pain in Child Health Global Research Training (Faculty Member)

2019-present, Society of Pediatric Psychology, Pediatric Pain Special Interest Group (Member)

2017-present, AMIGO (The ACR/CARRA Rheumatology Mentoring Interest Group For Pediatric Rheumatologists) (Member)

2015-present, Childhood Arthritis & Rheumatology Research Alliance (CARRA)

2014-present, American College of Rheumatology